Muscular Dystrophies, Limb-Girdle
"Muscular Dystrophies, Limb-Girdle" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogenous group of inherited muscular dystrophy that can be autosomal dominant or autosomal recessive. There are many forms (called LGMDs) involving genes encoding muscle membrane proteins such as the sarcoglycan (SARCOGLYCANS) complex that interacts with DYSTROPHIN. The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the HIPS and SHOULDERS (the pelvic and shoulder girdles).
| Descriptor ID |
D049288
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| MeSH Number(s) |
C05.651.534.500.280 C10.668.491.175.500.149 C16.320.577.280
|
| Concept/Terms |
Muscular Dystrophies, Limb-Girdle- Muscular Dystrophies, Limb-Girdle
- Muscular Dystrophies, Limb Girdle
- Myopathic Limb-Girdle Syndrome
- Muscular Dystrophy, Limb-Girdle
- Muscular Dystrophy, Limb Girdle
- Limb-Girdle Syndrome
- Limb-Girdle Muscular Dystrophies
- Limb Girdle Muscular Dystrophies
- Limb-Girdle Muscular Dystrophy
- Limb Girdle Muscular Dystrophy
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Below are MeSH descriptors whose meaning is more general than "Muscular Dystrophies, Limb-Girdle".
Below are MeSH descriptors whose meaning is more specific than "Muscular Dystrophies, Limb-Girdle".
This graph shows the total number of publications written about "Muscular Dystrophies, Limb-Girdle" by people in this website by year, and whether "Muscular Dystrophies, Limb-Girdle" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Muscular Dystrophies, Limb-Girdle" by people in Profiles.
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Editors' Note: Prospective Natural History Study in 24 Adult Patients With LGMDR12 Over 2 Years of Follow-up: Quantitative MRI and Clinical Outcome Measures. Neurology. 2023 02 14; 100(7):353.
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Effects of Glucocorticoids in Murine Models of Duchenne and Limb-Girdle Muscular Dystrophy. Methods Mol Biol. 2023; 2587:467-478.
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A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping. Dis Model Mech. 2019 11 04; 13(2).
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Intermittent Glucocorticoid Dosing Improves Muscle Repair and Function in Mice with Limb-Girdle Muscular Dystrophy. Am J Pathol. 2017 Nov; 187(11):2520-2535.
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Reengineering a transmembrane protein to treat muscular dystrophy using exon skipping. J Clin Invest. 2015 Nov 02; 125(11):4186-95.
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Muscle hypertrophy induced by myostatin inhibition accelerates degeneration in dysferlinopathy. Hum Mol Genet. 2015 Oct 15; 24(20):5711-9.
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Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. Am J Hum Genet. 2013 Jul 11; 93(1):181-90.
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Eight new mutations and the expanding phenotype variability in muscular dystrophy caused by ANO5. Neurology. 2012 Mar 20; 78(12):897-903.
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Diaphragm displays early and progressive functional deficits in dysferlin-deficient mice. Muscle Nerve. 2010 Jul; 42(1):22-9.
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Dystrophinopathy in girls with limb girdle muscular dystrophy phenotype. J Clin Neuromuscul Dis. 2010 Jun; 11(4):203-8.