 Clostridium difficile
"Clostridium difficile" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.
| Descriptor ID |
D016360
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| MeSH Number(s) |
B03.300.390.400.200.250 B03.510.415.400.200.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Clostridium difficile".
Below are MeSH descriptors whose meaning is more specific than "Clostridium difficile".
This graph shows the total number of publications written about "Clostridium difficile" by people in this website by year, and whether "Clostridium difficile" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 2 | 0 | 2 | | 1991 | 2 | 0 | 2 | | 1992 | 4 | 0 | 4 | | 1993 | 2 | 1 | 3 | | 1995 | 2 | 0 | 2 | | 1996 | 2 | 0 | 2 | | 2001 | 2 | 0 | 2 | | 2004 | 2 | 0 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 2 | 2 | 4 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2009 | 3 | 0 | 3 | | 2010 | 3 | 0 | 3 | | 2011 | 9 | 3 | 12 | | 2012 | 6 | 0 | 6 | | 2013 | 14 | 2 | 16 | | 2014 | 9 | 4 | 13 | | 2015 | 11 | 1 | 12 | | 2016 | 10 | 3 | 13 | | 2017 | 6 | 3 | 9 | | 2018 | 8 | 2 | 10 | | 2019 | 5 | 7 | 12 | | 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Clostridium difficile" by people in Profiles.
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Gjonbalaj M, Keith JW, Do MH, Hohl TM, Pamer EG, Becattini S. Antibiotic Degradation by Commensal Microbes Shields Pathogens. Infect Immun. 2020 03 23; 88(4).
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Peterson LR, O'Grady S, Keegan M, Fisher A, Zelencik S, Kufner B, Shah M, Lim R, Schora D, Das S, Singh K. Reduced Clostridioides difficile infection in a pragmatic stepped-wedge initiative using admission surveillance to detect colonization. PLoS One. 2020; 15(3):e0230475.
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Cotter JM, Nicholson MR, Kociolek LK. An Infectious Diseases Perspective on Fecal Microbiota Transplantation for Clostridioides difficile Infection in Children. J Pediatric Infect Dis Soc. 2019 Dec 27; 8(6):580-584.
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Lei DK, Ollech JE, Andersen M, Weisshof R, Zmeter N, Sossenheimer P, Rubin DT. Long-Duration Oral Vancomycin to Treat Clostridioides difficile in Patients With Inflammatory Bowel Disease Is Associated With a Low Rate of Recurrence. Am J Gastroenterol. 2019 12; 114(12):1904-1908.
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Westblade LF, Satlin MJ, Albakry S, Botticelli B, Robertson A, Alston T, Magruder M, Zhang LT, Edusei E, Chan K, Lubetzky M, Dadhania DM, Pamer EG, Suthanthiran M, Lee JR. Gastrointestinal pathogen colonization and the microbiome in asymptomatic kidney transplant recipients. Transpl Infect Dis. 2019 Dec; 21(6):e13167.
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Balaji A, Ozer EA, Kociolek LK. Clostridioides difficile Whole-Genome Sequencing Reveals Limited Within-Host Genetic Diversity in a Pediatric Cohort. J Clin Microbiol. 2019 09; 57(9).
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Ochfeld E, Balmert LC, Patel SJ, Muller WJ, Kociolek LK. Risk factors for Clostridioides (Clostridium) difficile infection following solid organ transplantation in children. Transpl Infect Dis. 2019 Oct; 21(5):e13149.
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Kociolek LK, Davidovics ZH, Kahn SA, Kellermayer R. Response to: Treatment of (Recurrent) Clostridioides difficile Infections in Children and Adults. J Pediatr Gastroenterol Nutr. 2019 08; 69(2):e58-e59.
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Borsky AE, Flores EJ, Berliner E, Chang C, Umscheid CA, Chang SM. Next Steps in Improving Healthcare Value: AHRQ Evidence-based Practice Center Program-Applying the Knowledge to Practice to Data Cycle to Strengthen the Value of Patient Care. J Hosp Med. 2019 05; 14(5):311-314.
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Balaji AB, Sichel JS, Kociolek LK. Lack of false-positive results for Clostridioides difficile toxins A and B using two commercial enzyme immunoassays in pediatric patients. Infect Control Hosp Epidemiol. 2019 07; 40(7):825-826.
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