 Clostridium difficile
"Clostridium difficile" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.
| Descriptor ID |
D016360
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| MeSH Number(s) |
B03.300.390.400.200.250 B03.510.415.400.200.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Clostridium difficile".
Below are MeSH descriptors whose meaning is more specific than "Clostridium difficile".
This graph shows the total number of publications written about "Clostridium difficile" by people in this website by year, and whether "Clostridium difficile" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 2 | 0 | 2 | | 1991 | 2 | 0 | 2 | | 1992 | 4 | 0 | 4 | | 1993 | 2 | 1 | 3 | | 1995 | 2 | 0 | 2 | | 1996 | 2 | 0 | 2 | | 2001 | 2 | 0 | 2 | | 2004 | 2 | 0 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 2 | 2 | 4 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2009 | 3 | 0 | 3 | | 2010 | 3 | 0 | 3 | | 2011 | 9 | 3 | 12 | | 2012 | 6 | 0 | 6 | | 2013 | 14 | 2 | 16 | | 2014 | 9 | 4 | 13 | | 2015 | 11 | 1 | 12 | | 2016 | 10 | 3 | 13 | | 2017 | 6 | 3 | 9 | | 2018 | 8 | 2 | 10 | | 2019 | 2 | 3 | 5 |
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Below are the most recent publications written about "Clostridium difficile" by people in Profiles.
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Ochfeld E, Balmert LC, Patel SJ, Muller WJ, Kociolek LK. Risk factors for Clostridioides (Clostridium) difficile infection following solid organ transplantation in children. Transpl Infect Dis. 2019 Oct; 21(5):e13149.
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Kociolek LK, Kutty PK, Polgreen PM, Beekmann SE. Healthcare provider diagnostic testing practices for identification of Clostridioides (Clostridium) difficile in children: an Emerging Infections Network survey. Infect Control Hosp Epidemiol. 2019 03; 40(3):276-280.
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Khanna S, Gupta A, Cifu AS. Treatment of Recurrent Clostridium difficile Infection-Reply. JAMA. 2019 02 05; 321(5):513.
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Mullane KM, Winston DJ, Nooka A, Morris MI, Stiff P, Dugan MJ, Holland H, Gregg K, Adachi JA, Pergam SA, Alexander BD, Dubberke ER, Broyde N, Gorbach SL, Sears PS. A Randomized, Placebo-controlled Trial of Fidaxomicin for Prophylaxis of Clostridium difficile-associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation. Clin Infect Dis. 2019 01 07; 68(2):196-203.
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Davidovics ZH, Michail S, Nicholson MR, Kociolek LK, Pai N, Hansen R, Schwerd T, Maspons A, Shamir R, Szajewska H, Thapar N, de Meij T, Mosca A, Vandenplas Y, Kahn SA, Kellermayer R. Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection and Other Conditions in Children: A Joint Position Paper From the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2019 01; 68(1):130-143.
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Gupta A, Cifu AS, Khanna S. Diagnosis and Treatment of Clostridium difficile Infection. JAMA. 2018 Sep 11; 320(10):1031-1032.
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Sandora TJ, Bryant KK, Cantey JB, Elward AM, Yokoe DS, Bartlett AH. SHEA neonatal intensive care unit (NICU) white paper series: Practical approaches to Clostridioides difficile prevention. Infect Control Hosp Epidemiol. 2018 10; 39(10):1149-1153.
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O'Gorman MA, Michaels MG, Kaplan SL, Otley A, Kociolek LK, Hoffenberg EJ, Kim KS, Nachman S, Pfefferkorn MD, Sentongo T, Sullivan JE, Sears P. Safety and Pharmacokinetic Study of Fidaxomicin in Children With Clostridium difficile-Associated Diarrhea: A Phase 2a Multicenter Clinical Trial. J Pediatric Infect Dis Soc. 2018 Aug 17; 7(3):210-218.
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Kociolek LK, Perdue ER, Fawley WN, Wilcox MH, Gerding DN, Johnson S. Correlation between restriction endonuclease analysis and PCR ribotyping for the identification of Clostridioides (Clostridium) difficile clinical strains. Anaerobe. 2018 Dec; 54:1-7.
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Kociolek LK, Gerding DN, Espinosa RO, Patel SJ, Shulman ST, Ozer EA. Clostridium difficile Whole Genome Sequencing Reveals Limited Transmission Among Symptomatic Children: A Single-Center Analysis. Clin Infect Dis. 2018 07 02; 67(2):229-234.
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