 Trophoblasts
"Trophoblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cells lining the outside of the BLASTOCYST. After binding to the ENDOMETRIUM, trophoblasts develop into two distinct layers, an inner layer of mononuclear cytotrophoblasts and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblasts, which form the early fetal-maternal interface (PLACENTA).
| Descriptor ID |
D014327
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| MeSH Number(s) |
A11.382.992 A16.254.500.766 A16.710.802
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trophoblasts".
Below are MeSH descriptors whose meaning is more specific than "Trophoblasts".
This graph shows the total number of publications written about "Trophoblasts" by people in this website by year, and whether "Trophoblasts" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1986 | 1 | 0 | 1 | | 1988 | 0 | 1 | 1 | | 1993 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 1 | 2 | 3 | | 2000 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 2 | 3 | | 2013 | 2 | 0 | 2 | | 2016 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Trophoblasts" by people in Profiles.
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Kliman HJ, Quaratella SB, Setaro AC, Siegman EC, Subha ZT, Tal R, Milano KM, Steck TL. Pathway of Maternal Serotonin to the Human Embryo and Fetus. Endocrinology. 2018 04 01; 159(4):1609-1629.
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Nadkarni NA, Rajakumar A, Mokhashi N, Burke SD, Rana S, Salahuddin S, Dang Q, Thadhani R, Krishnan R, Stossel TP, Karumanchi SA. Gelsolin is an endogenous inhibitor of syncytiotrophoblast extracellular vesicle shedding in pregnancy. Pregnancy Hypertens. 2016 Oct; 6(4):333-339.
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Zsengellér ZK, Rajakumar A, Hunter JT, Salahuddin S, Rana S, Stillman IE, Ananth Karumanchi S. Trophoblast mitochondrial function is impaired in preeclampsia and correlates negatively with the expression of soluble fms-like tyrosine kinase 1. Pregnancy Hypertens. 2016 Oct; 6(4):313-319.
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Gandley RE, Althouse A, Jeyabalan A, Bregand-White JM, McGonigal S, Myerski AC, Gallaher M, Powers RW, Hubel CA. Low Soluble Syndecan-1 Precedes Preeclampsia. PLoS One. 2016; 11(6):e0157608.
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Tilburgs T, Crespo ÂC, van der Zwan A, Rybalov B, Raj T, Stranger B, Gardner L, Moffett A, Strominger JL. Human HLA-G+ extravillous trophoblasts: Immune-activating cells that interact with decidual leukocytes. Proc Natl Acad Sci U S A. 2015 Jun 09; 112(23):7219-24.
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Choi HJ, Sanders TA, Tormos KV, Ameri K, Tsai JD, Park AM, Gonzalez J, Rajah AM, Liu X, Quinonez DM, Rinaudo PF, Maltepe E. ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement. PLoS One. 2013; 8(2):e56949.
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Salcedo SP, Chevrier N, Lacerda TL, Ben Amara A, Gerart S, Gorvel VA, de Chastellier C, Blasco JM, Mege JL, Gorvel JP. Pathogenic brucellae replicate in human trophoblasts. J Infect Dis. 2013 Apr; 207(7):1075-83.
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Kshirsagar SK, Alam SM, Jasti S, Hodes H, Nauser T, Gilliam M, Billstrand C, Hunt JS, Petroff MG. Immunomodulatory molecules are released from the first trimester and term placenta via exosomes. Placenta. 2012 Dec; 33(12):982-90.
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Ding D, Scott NM, Thompson EE, Chaiworapongsa T, Torres R, Billstrand C, Murray K, Dexheimer PJ, Ismail M, Kay H, Levy S, Romero R, Lindheimer MD, Nicolae DL, Ober C. Increased protein-coding mutations in the mitochondrial genome of African American women with preeclampsia. Reprod Sci. 2012 Dec; 19(12):1343-51.
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Rajakumar A, Cerdeira AS, Rana S, Zsengeller Z, Edmunds L, Jeyabalan A, Hubel CA, Stillman IE, Parikh SM, Karumanchi SA. Transcriptionally active syncytial aggregates in the maternal circulation may contribute to circulating soluble fms-like tyrosine kinase 1 in preeclampsia. Hypertension. 2012 Feb; 59(2):256-64.
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