Polymerase Chain Reaction
"Polymerase Chain Reaction" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
|Polymerase Chain Reaction
- Polymerase Chain Reaction
- Polymerase Chain Reactions
- Reaction, Polymerase Chain
- Reactions, Polymerase Chain
- Inverse PCR
- PCR, Inverse
- Inverse Polymerase Chain Reaction
- Anchored PCR
- PCR, Anchored
- Anchored Polymerase Chain Reaction
Below are MeSH descriptors whose meaning is more general than "Polymerase Chain Reaction".
Below are MeSH descriptors whose meaning is more specific than "Polymerase Chain Reaction".
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Below are the most recent publications written about "Polymerase Chain Reaction" by people in Profiles.
Serum Cytomegalovirus Polymerase Chain Reaction Test Is a Valuable Negative Predictor of Infection in Acute Severe Ulcerative Colitis. Dig Dis Sci. 2023 Mar; 68(3):897-901.
Ultra-Sensitive Quantification of Protein and mRNA in Single Mammalian Cells with Digital PLA. Methods Mol Biol. 2022; 2386:157-169.
Effectiveness of mRNA Covid-19 Vaccine among U.S. Health Care Personnel. N Engl J Med. 2021 12 16; 385(25):e90.
COVID-19 reinfection: a rapid systematic review of case reports and case series. J Investig Med. 2021 08; 69(6):1253-1255.
Liver transplantation for acute liver failure in a SARS-CoV-2 PCR-positive patient. Am J Transplant. 2021 08; 21(8):2890-2894.
Humoral Immune Response to SARS-CoV-2 in Iceland. N Engl J Med. 2020 10 29; 383(18):1724-1734.
Performance and Utilization of a Laboratory-Developed Nucleic Acid Amplification Test (NAAT) for the Diagnosis of Pulmonary and Extrapulmonary Tuberculosis in a Low-Prevalence Area. Am J Clin Pathol. 2020 06 08; 154(1):115-123.
Detection of Lactate Dehydrogenase Elevating Virus in a Mouse Vivarium Using an Exhaust Air Dust Health Monitoring Program. J Am Assoc Lab Anim Sci. 2020 05 01; 59(3):328-333.
Nucleic Acid-Based Screening of Maternal Serum to Detect Viruses in Women with Labor or PROM. Reprod Sci. 2020 02; 27(2):537-544.
Whom Should We Test for COVID-19? Performance of a Symptom and Risk Factor Questionnaire on COVID-19 Test Results and Patient Outcomes in an Immediate Care Setting. J Prim Care Community Health. 2020 Jan-Dec; 11:2150132720981297.