 Granulocyte Colony-Stimulating Factor
"Granulocyte Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.
| Descriptor ID |
D016179
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| MeSH Number(s) |
D12.644.276.374.410.240.350 D12.776.395.240.200 D12.776.467.374.410.240.350 D23.529.374.410.240.350
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Granulocyte Colony-Stimulating Factor".
Below are MeSH descriptors whose meaning is more specific than "Granulocyte Colony-Stimulating Factor".
This graph shows the total number of publications written about "Granulocyte Colony-Stimulating Factor" by people in this website by year, and whether "Granulocyte Colony-Stimulating Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1993 | 1 | 0 | 1 | | 1994 | 2 | 1 | 3 | | 1995 | 2 | 5 | 7 | | 1996 | 4 | 4 | 8 | | 1997 | 5 | 7 | 12 | | 1998 | 4 | 7 | 11 | | 1999 | 6 | 1 | 7 | | 2000 | 5 | 3 | 8 | | 2001 | 4 | 5 | 9 | | 2002 | 2 | 1 | 3 | | 2003 | 5 | 2 | 7 | | 2004 | 0 | 3 | 3 | | 2005 | 0 | 3 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 4 | 3 | 7 | | 2009 | 1 | 3 | 4 | | 2010 | 2 | 0 | 2 | | 2011 | 0 | 1 | 1 | | 2014 | 1 | 1 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 2 | 1 | 3 | | 2017 | 2 | 0 | 2 | | 2018 | 1 | 1 | 2 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Granulocyte Colony-Stimulating Factor" by people in Profiles.
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Curigliano G, Banerjee S, Cervantes A, Garassino MC, Garrido P, Girard N, Haanen J, Jordan K, Lordick F, Machiels JP, Michielin O, Peters S, Tabernero J, Douillard JY, Pentheroudakis G. Managing cancer patients during the COVID-19 pandemic: an ESMO multidisciplinary expert consensus. Ann Oncol. 2020 10; 31(10):1320-1335.
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Calip GS, Moran KM, Sweiss KI, Patel PR, Wu Z, Adimadhyam S, Lee TA, Ko NY, Quigley JG, Chiu BC. Myelodysplastic syndrome and acute myeloid leukemia after receipt of granulocyte colony-stimulating factors in older patients with non-Hodgkin lymphoma. Cancer. 2019 04 01; 125(7):1143-1154.
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Nguyen AB, Lourenço L, Chung BB, Imamura T, Rodgers D, Besser SA, Murks C, Riley T, Powers J, Raikhelkar J, Kalantari S, Sarswat N, Jeevanandam V, Kim G, Sayer G, Uriel N. Increase in short-term risk of rejection in heart transplant patients receiving granulocyte colony-stimulating factor. J Heart Lung Transplant. 2018 11; 37(11):1322-1328.
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Singh AD, Parmar S, Patel K, Shah S, Shore T, Gergis U, Mayer S, Phillips A, Hsu JM, Niesvizky R, Mark TM, Pearse R, Rossi A, van Besien K. Granulocyte Colony-Stimulating Factor Use after Autologous Peripheral Blood Stem Cell Transplantation: Comparison of Two Practices. Biol Blood Marrow Transplant. 2018 02; 24(2):288-293.
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Banuelos J, Cao Y, Shin SC, Bochner BS, Avila P, Li S, Jiang X, Lingen MW, Schleimer RP, Lu NZ. Granulocyte colony-stimulating factor blockade enables dexamethasone to inhibit lipopolysaccharide-induced murine lung neutrophils. PLoS One. 2017; 12(5):e0177884.
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Buyuk E, Asemota OA, Merhi Z, Charron MJ, Berger DS, Zapantis A, Jindal SK. Serum and follicular fluid monocyte chemotactic protein-1 levels are elevated in obese women and are associated with poorer clinical pregnancy rate after in vitro fertilization: a pilot study. Fertil Steril. 2017 03; 107(3):632-640.e3.
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Slight-Webb S, Lu R, Ritterhouse LL, Munroe ME, Maecker HT, Fathman CG, Utz PJ, Merrill JT, Guthridge JM, James JA. Autoantibody-Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity. Arthritis Rheumatol. 2016 10; 68(10):2492-502.
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Agiro A, Ma Q, Acheson AK, Wu SJ, Patt DA, Barron JJ, Malin JL, Rosenberg A, Schilsky RL, Lyman GH. Risk of Neutropenia-Related Hospitalization in Patients Who Received Colony-Stimulating Factors With Chemotherapy for Breast Cancer. J Clin Oncol. 2016 11 10; 34(32):3872-3879.
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Rojek K, Nickels E, Neistadt B, Marquez R, Wickrema A, Artz A, van Besien K, Larson RA, Lee MK, Segal JP, King MC, Walsh T, Shimamura A, Keel SB, Churpek JE, Godley LA. Identifying Inherited and Acquired Genetic Factors Involved in Poor Stem Cell Mobilization and Donor-Derived Malignancy. Biol Blood Marrow Transplant. 2016 11; 22(11):2100-2103.
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Nakamura Y, Ishikawa K, Kai Y, Shimada H, Kawano M, Iwasaki T, Tagomori H, Tanata K, Tsumura H, Arakane M, Nishida H, Yokoyama S, Hatano Y, Fujiwara S. Case of malignant melanoma that developed the ability to secrete granulocyte colony-stimulating factor. J Dermatol. 2016 May; 43(5):580-2.
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