 Prostatic Intraepithelial Neoplasia
"Prostatic Intraepithelial Neoplasia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer.
| Descriptor ID |
D019048
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| MeSH Number(s) |
C04.557.470.200.240.500
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| Concept/Terms |
Prostatic Intraepithelial Neoplasia- Prostatic Intraepithelial Neoplasia
- Neoplasia, Prostatic Intraepithelial
- Intraepithelial Neoplasia, Prostatic
- Prostatic Intraepithelial Neoplasias
- Prostatic Intraepithelial Neoplasms
- Intraepithelial Neoplasm, Prostatic
- Intraepithelial Neoplasms, Prostatic
- Neoplasm, Prostatic Intraepithelial
- Neoplasms, Prostatic Intraepithelial
- Prostatic Intraepithelial Neoplasm
- Intraepithelial Prostatic Neoplasia
- Intraepithelial Prostatic Neoplasias
- Neoplasia, Intraepithelial Prostatic
- Prostatic Neoplasia, Intraepithelial
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Below are MeSH descriptors whose meaning is more general than "Prostatic Intraepithelial Neoplasia".
Below are MeSH descriptors whose meaning is more specific than "Prostatic Intraepithelial Neoplasia".
This graph shows the total number of publications written about "Prostatic Intraepithelial Neoplasia" by people in this website by year, and whether "Prostatic Intraepithelial Neoplasia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Prostatic Intraepithelial Neoplasia" by people in Profiles.
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Aaron-Brooks LM, Sasaki T, Vickman RE, Wei L, Franco OE, Ji Y, Crawford SE, Hayward SW. Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse. Prostate. 2019 06; 79(9):980-993.
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Brait M, Banerjee M, Maldonado L, Ooki A, Loyo M, Guida E, Izumchenko E, Mangold L, Humphreys E, Rosenbaum E, Partin A, Sidransky D, Hoque MO. Promoter methylation of MCAM, ERa and ERß in serum of early stage prostate cancer patients. Oncotarget. 2017 Feb 28; 8(9):15431-15440.
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Mehta V, Rycyna K, Baesens BM, Barkan GA, Paner GP, Flanigan RC, Wojcik EM, Venkataraman G. Predictors of Gleason Score (GS) upgrading on subsequent prostatectomy: a single Institution study in a cohort of patients with GS 6. Int J Clin Exp Pathol. 2012; 5(6):496-502.
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Rapp DE, Msezane LP, Reynolds WS, Lotan TL, Obara P, O'Connor RC, Taxy JB, Gerber GS, Zagaja GP. Recutting prostate needle core biopsies with high grade prostatic intraepithelial neoplasia increases detection of adenocarcinoma. Can J Urol. 2009 Feb; 16(1):4484-9.
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Posadas EM, Al-Ahmadie H, Robinson VL, Jagadeeswaran R, Otto K, Kasza KE, Tretiakov M, Siddiqui J, Pienta KJ, Stadler WM, Rinker-Schaeffer C, Salgia R. FYN is overexpressed in human prostate cancer. BJU Int. 2009 Jan; 103(2):171-7.
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Lotan TL, Lyon M, Huo D, Taxy JB, Brendler C, Foster BA, Stadler W, Rinker-Schaeffer CW. Up-regulation of MKK4, MKK6 and MKK7 during prostate cancer progression: an important role for SAPK signalling in prostatic neoplasia. J Pathol. 2007 Aug; 212(4):386-94.
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Cibull TL, Jones TD, Li L, Eble JN, Ann Baldridge L, Malott SR, Luo Y, Cheng L. Overexpression of Pim-1 during progression of prostatic adenocarcinoma. J Clin Pathol. 2006 Mar; 59(3):285-8.
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Ashida S, Nakagawa H, Katagiri T, Furihata M, Iiizumi M, Anazawa Y, Tsunoda T, Takata R, Kasahara K, Miki T, Fujioka T, Shuin T, Nakamura Y. Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs. Cancer Res. 2004 Sep 01; 64(17):5963-72.
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Gounari F, Signoretti S, Bronson R, Klein L, Sellers WR, Kum J, Siermann A, Taketo MM, von Boehmer H, Khazaie K. Stabilization of beta-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia. Oncogene. 2002 Jun 13; 21(26):4099-107.
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Alsikafi NF, Brendler CB, Gerber GS, Yang XJ. High-grade prostatic intraepithelial neoplasia with adjacent atypia is associated with a higher incidence of cancer on subsequent needle biopsy than high-grade prostatic intraepithelial neoplasia alone. Urology. 2001 Feb; 57(2):296-300.
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