Enkephalin, Ala(2)-MePhe(4)-Gly(5)-
"Enkephalin, Ala(2)-MePhe(4)-Gly(5)-" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enkephalin analog that selectively binds to the MU OPIOID RECEPTOR. It is used as a model for drug permeability experiments.
| Descriptor ID |
D020875
|
| MeSH Number(s) |
D12.644.400.575.281.075 D12.776.631.650.575.281.075
|
| Concept/Terms |
Enkephalin, Ala(2)-MePhe(4)-Gly(5)-- Enkephalin, Ala(2)-MePhe(4)-Gly(5)-
- 2-Ala-4-MePhe-5-Gly-Enkephalin
- 2 Ala 4 MePhe 5 Gly Enkephalin
- Ala(2)-MePhe(4)-Gly-ol(5) Enkephalin
- DAGO
- DAMGE
- D-Ala2-NMe-Phe4-Gly-ol Enkephalin
- D Ala2 NMe Phe4 Gly ol Enkephalin
- Enkephalin, D-Ala2-NMe-Phe4-Gly-ol
- DAGOL
- Tyr-Ala-Gly-(NMe)Phe-Gly-ol
- Enkephalin, alanyl(2)-methylphenylalanyl(4)-glycine(5)-
- D-Ala(2)-MePhe(4)-Gly-ol(5) Enkephalin
- DAMGO
|
Below are MeSH descriptors whose meaning is more general than "Enkephalin, Ala(2)-MePhe(4)-Gly(5)-".
Below are MeSH descriptors whose meaning is more specific than "Enkephalin, Ala(2)-MePhe(4)-Gly(5)-".
This graph shows the total number of publications written about "Enkephalin, Ala(2)-MePhe(4)-Gly(5)-" by people in this website by year, and whether "Enkephalin, Ala(2)-MePhe(4)-Gly(5)-" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 0 | 3 | 3 |
| 2007 | 0 | 3 | 3 |
| 2009 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Enkephalin, Ala(2)-MePhe(4)-Gly(5)-" by people in Profiles.
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Dynamic Rhythmogenic Network States Drive Differential Opioid Responses in the In Vitro Respiratory Network. J Neurosci. 2021 12 01; 41(48):9919-9931.
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Nicotinic modulation of descending pain control circuitry. Pain. 2017 Oct; 158(10):1938-1950.
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Opioid microinjection into raphe magnus modulates cardiorespiratory function in mice and rats. Am J Physiol Regul Integr Comp Physiol. 2009 Nov; 297(5):R1400-8.
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The effects of daikenchuto (DKT) on propulsive motility in the colon. J Surg Res. 2010 Nov; 164(1):84-90.
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G proteins in rat prefrontal cortex (PFC) are differentially activated as a function of oxygen status and PFC region. J Chem Neuroanat. 2009 Mar; 37(2):112-7.
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Activity of murine raphe magnus cells predicts tachypnea and on-going nociceptive responsiveness. J Neurophysiol. 2007 Dec; 98(6):3121-33.
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Attenuation of vascular permeability by methylnaltrexone: role of mOP-R and S1P3 transactivation. Am J Respir Cell Mol Biol. 2007 Aug; 37(2):222-31.
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Lobeline, a potential pharmacotherapy for drug addiction, binds to mu opioid receptors and diminishes the effects of opioid receptor agonists. Drug Alcohol Depend. 2007 Jul 10; 89(2-3):282-91.
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Hypoxia modulates cholinergic but not opioid activation of G proteins in rat hippocampus. Hippocampus. 2007; 17(10):934-42.
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Raphe magnus neurons help protect reactions to visceral pain from interruption by cutaneous pain. J Neurophysiol. 2006 Dec; 96(6):3423-32.