"gamma Catenin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-functional catenin that is highly homologous to BETA CATENIN. Gamma catenin binds CADHERINS and helps link their cytoplasmic tails to ACTIN in the CYTOSKELETON via ALPHA CATENIN. It is also found in DESMOSOMES where it mediates the link between DESMOSOMAL CADHERINS and DESMOPLAKIN.
| Descriptor ID |
D051185
|
| MeSH Number(s) |
D12.776.091.500 D12.776.220.145.750
|
| Concept/Terms |
gamma Catenin- gamma Catenin
- Catenin, gamma
- Desmoplakin III
- Junctional Plakoglobin
- Plakoglobin, Junctional
- Plakoglobin
- Junction Plakoglobin
- Plakoglobin, Junction
- gamma-Catenin
|
Below are MeSH descriptors whose meaning is more general than "gamma Catenin".
Below are MeSH descriptors whose meaning is more specific than "gamma Catenin".
This graph shows the total number of publications written about "gamma Catenin" by people in this website by year, and whether "gamma Catenin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "gamma Catenin" by people in Profiles.
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Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion. PLoS One. 2012; 7(11):e47842.
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Abnormal immunoreactivity of the E-cadherin/catenin (alpha-, beta-, and gamma-) complex in premalignant and malignant non-melanocytic skin tumours. J Pathol. 2002 Feb; 196(2):154-62.
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Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation. J Biol Chem. 2002 Feb 15; 277(7):5548-55.
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The potential role of abnormal E-cadherin and alpha-, beta- and gamma-catenin immunoreactivity in the determination of the biological behaviour of keratoacanthoma. Br J Dermatol. 2001 Oct; 145(4):582-9.
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Altered gamma-catenin expression correlates with poor survival in patients with bladder cancer. J Urol. 1998 Nov; 160(5):1889-93.
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Posttranslational regulation of plakoglobin expression. Influence of the desmosomal cadherins on plakoglobin metabolic stability. J Biol Chem. 1994 Dec 09; 269(49):31214-23.