Leukemia, Large Granular Lymphocytic
"Leukemia, Large Granular Lymphocytic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease.
| Descriptor ID |
D054066
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| MeSH Number(s) |
C04.557.337.428.580.049 C15.604.515.560.575.049 C20.683.515.528.582.049
|
| Concept/Terms |
Leukemia, Large Granular Lymphocytic- Leukemia, Large Granular Lymphocytic
- Aggressive NK Cell Leukemia
- Leukemia, Lymphocytic, Large Granular
- Large Granular Lymphocyte Leukemia
- LGL Leukemia
- LGL Leukemias
- Leukemias, LGL
- Lymphoproliferative Disease of Large Granular Lymphocytes
- Leukemia, LGL
- Aggressive Natural Killer Cell Leukemia
- Lymphoproliferative Disease of Granular Lymphocytes
Leukemia, T-Cell Large Granular Lymphocytic- Leukemia, T-Cell Large Granular Lymphocytic
- Leukemia, T Cell Large Granular Lymphocytic
- T-LGL Leukemia
- Leukemias, T-LGL
- T LGL Leukemia
- T-LGL Leukemias
- T-Cell Large Granular Lymphocyte Leukemia
- T Cell Large Granular Lymphocyte Leukemia
- T-Cell Large Granular Lymphocytic Leukemia
- T Cell Large Granular Lymphocytic Leukemia
- Leukemia, T-LGL
- Leukemia, T LGL
- Large Granular Lymphocytosis
- Granular Lymphocytoses, Large
- Granular Lymphocytosis, Large
- Large Granular Lymphocytoses
- Lymphocytoses, Large Granular
- Lymphocytosis, Large Granular
Leukemia, Natural Killer Cell Large Granular Lymphocytic- Leukemia, Natural Killer Cell Large Granular Lymphocytic
- Natural Killer Cell Large Granular Lymphocytic Leukemia
- Leukemia, NK-LGL
- Leukemia, NK LGL
- NK-Cell Large Granular Lymphocytic Leukemia
- NK Cell Large Granular Lymphocytic Leukemia
- NK-LGL Leukemia
- Leukemias, NK-LGL
- NK LGL Leukemia
- NK-LGL Leukemias
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Below are MeSH descriptors whose meaning is more general than "Leukemia, Large Granular Lymphocytic".
Below are MeSH descriptors whose meaning is more specific than "Leukemia, Large Granular Lymphocytic".
This graph shows the total number of publications written about "Leukemia, Large Granular Lymphocytic" by people in this website by year, and whether "Leukemia, Large Granular Lymphocytic" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukemia, Large Granular Lymphocytic" by people in Profiles.
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STAT3 mutations are frequent in CD30+ T-cell lymphomas and T-cell large granular lymphocytic leukemia. Leukemia. 2013 Nov; 27(11):2244-7.
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Refining the diagnosis of T-cell large granular lymphocytic leukemia by combining distinct patterns of antigen expression with T-cell clonality studies. Leukemia. 2011 Sep; 25(9):1439-43.