 Angiostatins
"Angiostatins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS INHIBITORS. Angiostatins contain four KRINGLE DOMAINS which are associated with their potent angiostatic activity.
| Descriptor ID |
D043168
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| MeSH Number(s) |
D08.622.610.500 D12.644.276.100.450.500 D12.776.124.790.223.580.500 D12.776.377.715.182.580.500 D12.776.467.100.450.500 D23.529.100.450.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Angiostatins".
Below are MeSH descriptors whose meaning is more specific than "Angiostatins".
This graph shows the total number of publications written about "Angiostatins" by people in this website by year, and whether "Angiostatins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 4 | 4 | | 2003 | 1 | 2 | 3 | | 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Angiostatins" by people in Profiles.
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Shantha Kumara HM, Tohme ST, Yan X, Nasar A, Senagore AJ, Kalady MF, Hyman N, Kim IY, Whelan RL. Plasma levels of angiostatin and endostatin remain unchanged for the first 3 weeks after colorectal cancer surgery. Surg Endosc. 2011 Jun; 25(6):1939-44.
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Dettin M, Bicciato S, Scarinci C, Cline E, Lingen MW, Di Bello C. Synthetic peptides derived from the angiostatin K4 domain inhibit endothelial cell migration. Chembiochem. 2003 Nov 07; 4(11):1238-42.
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Khodarev NN, Yu J, Labay E, Darga T, Brown CK, Mauceri HJ, Yassari R, Gupta N, Weichselbaum RR. Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells. J Cell Sci. 2003 Mar 15; 116(Pt 6):1013-22.
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Gorski DH, Mauceri HJ, Salloum RM, Halpern A, Seetharam S, Weichselbaum RR. Prolonged treatment with angiostatin reduces metastatic burden during radiation therapy. Cancer Res. 2003 Jan 15; 63(2):308-11.
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Grdina DJ, Kataoka Y, Murley JS, Swedberg K, Lee JY, Hunter N, Weichselbaum RR, Milas L. Antimetastatic effectiveness of amifostine therapy following surgical removal of Sa-NH tumors in mice. Semin Oncol. 2002 Dec; 29(6 Suppl 19):22-8.
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Mauceri HJ, Seetharam S, Beckett MA, Schumm LP, Koons A, Gupta VK, Park JO, Manan A, Lee JY, Montag AG, Kufe DW, Weichselbaum RR. Angiostatin potentiates cyclophosphamide treatment of metastatic disease. Cancer Chemother Pharmacol. 2002 Nov; 50(5):412-8.
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Mauceri HJ, Seetharam S, Beckett MA, Lee JY, Gupta VK, Gately S, Stack MS, Brown CK, Swedberg K, Kufe DW, Weichselbaum RR. Tumor production of angiostatin is enhanced after exposure to TNF-alpha. Int J Cancer. 2002 Feb 01; 97(4):410-5.
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Grdina DJ, Kataoka Y, Murley JS, Hunter N, Weichselbaum RR, Milas L. Inhibition of spontaneous metastases formation by amifostine. Int J Cancer. 2002 Jan 10; 97(2):135-41.
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Gupta N, Nodzenski E, Khodarev NN, Yu J, Khorasani L, Beckett MA, Kufe DW, Weichselbaum RR. Angiostatin effects on endothelial cells mediated by ceramide and RhoA. EMBO Rep. 2001 Jun; 2(6):536-40.
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Hari D, Beckett MA, Sukhatme VP, Dhanabal M, Nodzenski E, Lu H, Mauceri HJ, Kufe DW, Weichselbaum RR. Angiostatin induces mitotic cell death of proliferating endothelial cells. Mol Cell Biol Res Commun. 2000 May; 3(5):277-82.
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