"Aldehyde Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that oxidizes an aldehyde in the presence of NAD+ and water to an acid and NADH. This enzyme was formerly classified as EC 1.1.1.70.
| Descriptor ID |
D000444
|
| MeSH Number(s) |
D08.811.682.657.163.249
|
| Concept/Terms |
Aldehyde Dehydrogenase- Aldehyde Dehydrogenase
- Dehydrogenase, Aldehyde
- D-Glucuronolactone Dehydrogenase
- D Glucuronolactone Dehydrogenase
- Dehydrogenase, D-Glucuronolactone
- Aldehyde Dehydrogenase (NAD(+))
- Aldehyde-NAD Oxidoreductase
- Aldehyde NAD Oxidoreductase
|
Below are MeSH descriptors whose meaning is more general than "Aldehyde Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Aldehyde Dehydrogenase".
This graph shows the total number of publications written about "Aldehyde Dehydrogenase" by people in this website by year, and whether "Aldehyde Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 1 | 2 |
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aldehyde Dehydrogenase" by people in Profiles.
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Enhanced Catecholamine Flux and Impaired Carbonyl Metabolism Disrupt Cardiac Mitochondrial Oxidative Phosphorylation in Diabetes Patients. Antioxid Redox Signal. 2021 08 01; 35(4):235-251.
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Aldehyde dehydrogenase 1-positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum. Sci Rep. 2017 07 13; 7(1):5283.
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EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells. Cancer Res. 2016 11 01; 76(21):6396-6409.
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Intragenic deletions of ALDH7A1 in pyridoxine-dependent epilepsy caused by Alu-Alu recombination. Neurology. 2015 Sep 01; 85(9):756-62.
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The sonic hedgehog signaling pathway maintains the cancer stem cell self-renewal of anaplastic thyroid cancer by inducing snail expression. J Clin Endocrinol Metab. 2014 Nov; 99(11):E2178-87.
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Intrapancreatic delivery of human umbilical cord blood aldehyde dehydrogenase-producing cells promotes islet regeneration. Diabetologia. 2012 Jun; 55(6):1755-60.
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Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles. Breast Cancer Res Treat. 2012 Feb; 132(1):175-87.
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Drug focus: Pharmacogenetic studies related to cyclophosphamide-based therapy. Pharmacogenomics. 2009 Dec; 10(12):1897-903.
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Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. Gastroenterology. 2009 Nov; 137(5):1768-75.
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FALDH reverses the deleterious action of oxidative stress induced by lipid peroxidation product 4-hydroxynonenal on insulin signaling in 3T3-L1 adipocytes. Diabetes. 2008 May; 57(5):1216-26.