"Biguanides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
| Descriptor ID |
D001645
|
| MeSH Number(s) |
D02.078.370.141
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Biguanides".
Below are MeSH descriptors whose meaning is more specific than "Biguanides".
This graph shows the total number of publications written about "Biguanides" by people in this website by year, and whether "Biguanides" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Biguanides" by people in Profiles.
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Agonist- and antagonist-induced up-regulation of surface 5-HT3 A receptors. Br J Pharmacol. 2015 Aug; 172(16):4066-77.
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Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy. Nat Commun. 2015 Feb 05; 6:6220.
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The AMP-activated protein kinase (AMPK) and cancer: many faces of a metabolic regulator. Cancer Lett. 2015 Jan 28; 356(2 Pt A):165-70.
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Noninsulin glucose-lowering agents for the treatment of patients on dialysis. Nat Rev Nephrol. 2013 Mar; 9(3):147-53.
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National trends in treatment of type 2 diabetes mellitus, 1994-2007. Arch Intern Med. 2008 Oct 27; 168(19):2088-94.
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Intracardiac phenylbiguanide causes excitation of spinal neurons by activation of cardiac sympathetic afferents. Eur J Pharmacol. 1992 May 27; 216(1):119-22.
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Analysis of postinspiratory activity of phrenic motoneurons with chemical and vagal reflexes. J Appl Physiol (1985). 1986 Oct; 61(4):1499-509.
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The effects of hypercapnia and cooling the ventral medullary surface on capsaicin induced respiratory reflexes. Respir Physiol. 1985 Jun; 60(3):377-85.