 Calcium Channel Blockers
"Calcium Channel Blockers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of drugs that act by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. Since they are inducers of vascular and other smooth muscle relaxation, they are used in the drug therapy of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms.
| Descriptor ID |
D002121
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| MeSH Number(s) |
D27.505.519.562.249 D27.505.954.411.192
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| Concept/Terms |
Calcium Channel Blockers- Calcium Channel Blockers
- Calcium Antagonists, Exogenous
- Exogenous Calcium Blockaders
- Blockaders, Exogenous Calcium
- Calcium Blockaders, Exogenous
- Calcium Channel Blocking Drugs
- Exogenous Calcium Inhibitors
- Inhibitors, Exogenous Calcium
- Calcium Inhibitors, Exogenous
- Exogenous Calcium Antagonists
- Antagonists, Exogenous Calcium
- Channel Blockers, Calcium
- Blockers, Calcium Channel
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Below are MeSH descriptors whose meaning is more general than "Calcium Channel Blockers".
Below are MeSH descriptors whose meaning is more specific than "Calcium Channel Blockers".
This graph shows the total number of publications written about "Calcium Channel Blockers" by people in this website by year, and whether "Calcium Channel Blockers" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1984 | 2 | 2 | 4 | | 1985 | 3 | 1 | 4 | | 1987 | 0 | 1 | 1 | | 1989 | 1 | 1 | 2 | | 1990 | 3 | 0 | 3 | | 1991 | 4 | 2 | 6 | | 1992 | 0 | 1 | 1 | | 1993 | 1 | 4 | 5 | | 1994 | 1 | 3 | 4 | | 1995 | 2 | 4 | 6 | | 1996 | 8 | 4 | 12 | | 1997 | 7 | 4 | 11 | | 1998 | 4 | 9 | 13 | | 1999 | 6 | 2 | 8 | | 2000 | 3 | 6 | 9 | | 2001 | 5 | 4 | 9 | | 2002 | 3 | 2 | 5 | | 2003 | 3 | 10 | 13 | | 2004 | 5 | 7 | 12 | | 2005 | 4 | 6 | 10 | | 2006 | 3 | 7 | 10 | | 2007 | 3 | 5 | 8 | | 2008 | 2 | 6 | 8 | | 2009 | 1 | 3 | 4 | | 2010 | 3 | 5 | 8 | | 2011 | 3 | 7 | 10 | | 2012 | 0 | 2 | 2 | | 2013 | 5 | 0 | 5 | | 2014 | 1 | 3 | 4 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 4 | 4 | | 2018 | 1 | 3 | 4 | | 2019 | 0 | 1 | 1 | | 2021 | 2 | 0 | 2 | | 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Calcium Channel Blockers" by people in Profiles.
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Goldstein ED, Wolcott Z, Garg G, Navarro K, Delic A, Yaghi S, Sederholm B, Prabhakaran S, Wong KH, McLean K, de Havenon AH. Effect of Antihypertensives by Class on Cerebral Small Vessel Disease: A Post Hoc Analysis of SPRINT-MIND. Stroke. 2022 Aug; 53(8):2435-2440.
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de Havenon A, Petersen N, Wolcott Z, Goldstein E, Delic A, Sheibani N, Anadani M, Sheth KN, Lansberg M, Turan T, Prabhakaran S. Effect of dihydropyridine calcium channel blockers on blood pressure variability in the SPRINT trial: a treatment effects approach. J Hypertens. 2022 03 01; 40(3):462-469.
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Brook RD, Kaciroti N, Bakris G, Dahlöf B, Pitt B, Velazquez E, Weber MA, Jamerson KA. Cardiovascular Benefits of Angiotensin-Converting Enzyme Inhibition Plus Calcium Channel Blockade in Patients Achieving Tight Blood Pressure Control and With Resistant Hypertension. Am J Hypertens. 2021 05 22; 34(5):531-539.
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Choksi TT, Zhang H, Chen T, Malhotra N. Outcomes of Hospitalized COVID-19 Patients Receiving Renin Angiotensin System Blockers and Calcium Channel Blockers. Am J Nephrol. 2021; 52(3):250-260.
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Cunningham PN, Chapman AB. The future of pharmacogenetics in the treatment of hypertension. Pharmacogenomics. 2019 02; 20(3):129-132.
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Brennan MB, Guihan M, Budiman-Mak E, Kang H, Lobo JM, Sutherland BL, Emanuele N, Huang ES, Sohn MW. Increasing SBP variability is associated with an increased risk of developing incident diabetic foot ulcers. J Hypertens. 2018 11; 36(11):2177-2184.
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Omboni S, Kario K, Bakris G, Parati G. Effect of antihypertensive treatment on 24-h blood pressure variability: pooled individual data analysis of ambulatory blood pressure monitoring studies based on olmesartan mono or combination treatment. J Hypertens. 2018 04; 36(4):720-733.
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Oparil S, Acelajado MC, Bakris GL, Berlowitz DR, Cífková R, Dominiczak AF, Grassi G, Jordan J, Poulter NR, Rodgers A, Whelton PK. Hypertension. Nat Rev Dis Primers. 2018 03 22; 4:18014.
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Brook RD, Kaciroti N, Bakris G, Dahlöf B, Pitt B, Velazquez E, Weber M, Zappe DH, Hau T, Jamerson KA. Prior Medications and the Cardiovascular Benefits From Combination Angiotensin-Converting Enzyme Inhibition Plus Calcium Channel Blockade Among High-Risk Hypertensive Patients. J Am Heart Assoc. 2018 01 04; 7(1).
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Magvanjav O, Gong Y, McDonough CW, Chapman AB, Turner ST, Gums JG, Bailey KR, Boerwinkle E, Beitelshees AL, Tanaka T, Kubo M, Pepine CJ, Cooper-DeHoff RM, Johnson JA. Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/ß-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials. J Am Heart Assoc. 2017 Nov 02; 6(11).
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