 Carbolines
"Carbolines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. These are similar to CARBAZOLES which are benzo-indoles.
| Descriptor ID |
D002243
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| MeSH Number(s) |
D03.383.725.150 D03.438.473.155 D03.494.154
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Carbolines".
Below are MeSH descriptors whose meaning is more specific than "Carbolines".
This graph shows the total number of publications written about "Carbolines" by people in this website by year, and whether "Carbolines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Carbolines" by people in Profiles.
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Papachristos A, Ratain MJ. Lurbinectedin-induced thrombocytopenia: the role of body surface area. Cancer Chemother Pharmacol. 2022 05; 89(5):573-575.
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Jimeno A, Sharma MR, Szyldergemajn S, Gore L, Geary D, Diamond JR, Fernandez Teruel C, Soto Matos-Pita A, Iglesias JL, Cullell-Young M, Ratain MJ. Phase I study of lurbinectedin, a synthetic tetrahydroisoquinoline that inhibits activated transcription, induces DNA single- and double-strand breaks, on a weekly × 2 every-3-week schedule. Invest New Drugs. 2017 08; 35(4):471-477.
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Califano JA, Khan Z, Noonan KA, Rudraraju L, Zhang Z, Wang H, Goodman S, Gourin CG, Ha PK, Fakhry C, Saunders J, Levine M, Tang M, Neuner G, Richmon JD, Blanco R, Agrawal N, Koch WM, Marur S, Weed DT, Serafini P, Borrello I. Tadalafil augments tumor specific immunity in patients with head and neck squamous cell carcinoma. Clin Cancer Res. 2015 Jan 01; 21(1):30-8.
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Elez ME, Tabernero J, Geary D, Macarulla T, Kang SP, Kahatt C, Pita AS, Teruel CF, Siguero M, Cullell-Young M, Szyldergemajn S, Ratain MJ. First-in-human phase I study of Lurbinectedin (PM01183) in patients with advanced solid tumors. Clin Cancer Res. 2014 Apr 15; 20(8):2205-14.
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Soukhova-O'Hare GK, Shah ZA, Lei Z, Nozdrachev AD, Rao CV, Gozal D. Erectile dysfunction in a murine model of sleep apnea. Am J Respir Crit Care Med. 2008 Sep 15; 178(6):644-50.
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Ehrenpreis ED. Irritable bowel syndrome. 10% to 20% of older adults have symptoms consistent with diagnosis. Geriatrics. 2005 Jan; 60(1):25-8.
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Maestripieri D, Martel FL, Nevison CM, Simpson MJ, Keverne EB. Anxiety in rhesus monkey infants in relation to interactions with their mother and other social companions. Dev Psychobiol. 1991 Dec; 24(8):571-81.
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Larson RA, Marley KA, Tuveson RW, Berenbaum MR. Beta-carboline alkaloids: mechanisms of phototoxicity to bacteria and insects. Photochem Photobiol. 1988 Nov; 48(5):665-74.
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