Myeloid-Derived Suppressor Cells
"Myeloid-Derived Suppressor Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogeneous, immature population of myeloid cells that can suppress the activity of T-CELLS and NATURAL KILLER CELLS in the INNATE IMMUNE RESPONSE and ADAPTIVE IMMUNE RESPONSE. They play important roles in ONCOGENESIS; INFLAMMATION; and INFECTION.
| Descriptor ID |
D000072737
|
| MeSH Number(s) |
A11.627.817
|
| Concept/Terms |
Myeloid-Derived Suppressor Cells- Myeloid-Derived Suppressor Cells
- Cell, Myeloid-Derived Suppressor
- Cells, Myeloid-Derived Suppressor
- Myeloid Derived Suppressor Cells
- Myeloid-Derived Suppressor Cell
- Suppressor Cell, Myeloid-Derived
- Suppressor Cells, Myeloid-Derived
- MDSCs
|
Below are MeSH descriptors whose meaning is more general than "Myeloid-Derived Suppressor Cells".
Below are MeSH descriptors whose meaning is more specific than "Myeloid-Derived Suppressor Cells".
This graph shows the total number of publications written about "Myeloid-Derived Suppressor Cells" by people in this website by year, and whether "Myeloid-Derived Suppressor Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myeloid-Derived Suppressor Cells" by people in Profiles.
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Loss-of-function of the hippo transducer TAZ reduces mammary tumor growth through a myeloid-derived suppressor cell-dependent mechanism. Cancer Gene Ther. 2022 11; 29(11):1791-1800.
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Myeloid-Derived Suppressor Cells Mediate T Cell Dysfunction in Nonhuman Primate TB Granulomas. mBio. 2021 12 21; 12(6):e0318921.
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Gut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma. Cancer Discov. 2021 05; 11(5):1248-1267.
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Therapies for tuberculosis and AIDS: myeloid-derived suppressor cells in focus. J Clin Invest. 2020 06 01; 130(6):2789-2799.
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Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment. JCI Insight. 2019 03 07; 4(5).
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Myeloid-derived suppressor cells increase and inhibit donor-reactive T cell responses to graft intestinal epithelium in intestinal transplant patients. Am J Transplant. 2018 10; 18(10):2544-2558.
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Induced pluripotent stem cells-derived myeloid-derived suppressor cells regulate the CD8+ T cell response. Stem Cell Res. 2018 05; 29:32-41.
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Host STING-dependent MDSC mobilization drives extrinsic radiation resistance. Nat Commun. 2017 11 23; 8(1):1736.
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C-C Chemokine Receptor Type 2-Dependent Migration of Myeloid-Derived Suppressor Cells in Protection of Islet Transplants. Transplantation. 2017 08; 101(8):1793-1800.
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Role of Cyclooxygenase-2 on Intermittent Hypoxia-Induced Lung Tumor Malignancy in a Mouse Model of Sleep Apnea. Sci Rep. 2017 03 16; 7:44693.