Myeloid-Derived Suppressor Cells
"Myeloid-Derived Suppressor Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogeneous, immature population of myeloid cells that can suppress the activity of T-CELLS and NATURAL KILLER CELLS in the INNATE IMMUNE RESPONSE and ADAPTIVE IMMUNE RESPONSE. They play important roles in ONCOGENESIS; INFLAMMATION; and INFECTION.
Descriptor ID |
D000072737
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MeSH Number(s) |
A11.627.817
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Concept/Terms |
Myeloid-Derived Suppressor Cells- Myeloid-Derived Suppressor Cells
- Cell, Myeloid-Derived Suppressor
- Cells, Myeloid-Derived Suppressor
- Myeloid Derived Suppressor Cells
- Myeloid-Derived Suppressor Cell
- Suppressor Cell, Myeloid-Derived
- Suppressor Cells, Myeloid-Derived
- MDSCs
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Below are MeSH descriptors whose meaning is more general than "Myeloid-Derived Suppressor Cells".
Below are MeSH descriptors whose meaning is more specific than "Myeloid-Derived Suppressor Cells".
This graph shows the total number of publications written about "Myeloid-Derived Suppressor Cells" by people in this website by year, and whether "Myeloid-Derived Suppressor Cells" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 0 | 1 |
2017 | 2 | 0 | 2 |
2018 | 2 | 0 | 2 |
2019 | 0 | 2 | 2 |
2020 | 2 | 1 | 3 |
2021 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myeloid-Derived Suppressor Cells" by people in Profiles.
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Radiotherapy Enhances Metastasis Through Immune Suppression by Inducing PD-L1 and MDSC in Distal Sites. Clin Cancer Res. 2024 May 01; 30(9):1945-1958.
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RNA m6A methylation and MDSCs: Roles and therapeutic implications for radiotherapy. Med. 2023 Dec 08; 4(12):863-874.
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Loss-of-function of the hippo transducer TAZ reduces mammary tumor growth through a myeloid-derived suppressor cell-dependent mechanism. Cancer Gene Ther. 2022 11; 29(11):1791-1800.
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Myeloid-Derived Suppressor Cells Mediate T Cell Dysfunction in Nonhuman Primate TB Granulomas. mBio. 2021 12 21; 12(6):e0318921.
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Gut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma. Cancer Discov. 2021 05; 11(5):1248-1267.
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Therapies for tuberculosis and AIDS: myeloid-derived suppressor cells in focus. J Clin Invest. 2020 06 01; 130(6):2789-2799.
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PTGES/PGE2 signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model. Oncogene. 2020 04; 39(15):3179-3194.
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IL6/STAT3 Signaling Orchestrates Premetastatic Niche Formation and Immunosuppressive Traits in Lung. Cancer Res. 2020 02 15; 80(4):784-797.
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Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment. JCI Insight. 2019 03 07; 4(5).
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Myeloid-derived suppressor cells increase and inhibit donor-reactive T cell responses to graft intestinal epithelium in intestinal transplant patients. Am J Transplant. 2018 10; 18(10):2544-2558.