"Diphosphonates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
Descriptor ID |
D004164
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MeSH Number(s) |
D02.705.429.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Diphosphonates".
Below are MeSH descriptors whose meaning is more specific than "Diphosphonates".
This graph shows the total number of publications written about "Diphosphonates" by people in this website by year, and whether "Diphosphonates" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
1995 | 1 | 0 | 1 |
1998 | 1 | 0 | 1 |
1999 | 1 | 1 | 2 |
2001 | 0 | 1 | 1 |
2006 | 1 | 0 | 1 |
2007 | 3 | 0 | 3 |
2008 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2011 | 1 | 1 | 2 |
2013 | 1 | 0 | 1 |
2014 | 2 | 2 | 4 |
2015 | 1 | 0 | 1 |
2016 | 3 | 0 | 3 |
2017 | 2 | 0 | 2 |
2019 | 0 | 2 | 2 |
2020 | 1 | 1 | 2 |
2021 | 2 | 1 | 3 |
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Below are the most recent publications written about "Diphosphonates" by people in Profiles.
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Evaluation of Frequency of Administration of Intravenous Bisphosphonate and Recurrent Skeletal-Related Events in Patients With Multiple Myeloma. JAMA Netw Open. 2021 07 01; 4(7):e2118410.
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Bisphosphonates and management of kidney stones and bone disease. Curr Opin Nephrol Hypertens. 2021 03 01; 30(2):184-189.
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Racial Disparities in Intravenous Bisphosphonate Use Among Older Patients With Multiple Myeloma Enrolled in Medicare. JCO Oncol Pract. 2021 03; 17(3):e294-e312.
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Secondary Fracture Prevention: Consensus Clinical Recommendations From a Multistakeholder Coalition. Orthop Nurs. 2020 May/Jun; 39(3):145-161.
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Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition. J Orthop Trauma. 2020 Apr; 34(4):e125-e141.
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Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition. J Bone Miner Res. 2020 01; 35(1):36-52.
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Distinct biomarkers for different bones in osteoporosis with rheumatoid arthritis. Arthritis Res Ther. 2019 07 15; 21(1):174.
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OSTEOPOROTIC FRACTURES DURING BISPHOSPHONATE DRUG HOLIDAY. Endocr Pract. 2018 Feb; 24(2):163-169.
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Low Bone Density and Bisphosphonate Use and the Risk of Kidney Stones. Clin J Am Soc Nephrol. 2017 Aug 07; 12(8):1284-1290.
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TBCRC-010: Phase I/II Study of Dasatinib in Combination with Zoledronic Acid for the Treatment of Breast Cancer Bone Metastasis. Clin Cancer Res. 2016 Dec 01; 22(23):5706-5712.