"Ethacrynic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
Descriptor ID |
D004976
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MeSH Number(s) |
D02.241.081.018.386.682.300 D02.241.511.316.682.200
|
Concept/Terms |
Ethacrynic Acid- Ethacrynic Acid
- Acid, Ethacrynic
- Etacrynic Acid
- Acid, Etacrynic
- Ethacrinic Acid
- Acid, Ethacrinic
|
Below are MeSH descriptors whose meaning is more general than "Ethacrynic Acid".
Below are MeSH descriptors whose meaning is more specific than "Ethacrynic Acid".
This graph shows the total number of publications written about "Ethacrynic Acid" by people in this website by year, and whether "Ethacrynic Acid" was a major or minor topic of these publications.
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Below are the most recent publications written about "Ethacrynic Acid" by people in Profiles.
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Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo. Neuroscience. 2007 Feb 09; 144(3):991-1003.
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Effects of trifluoperazine, ouabain, and ethacrynic acid on intestinal calcium transport. Am J Physiol. 1983 Feb; 244(2):G111-5.
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Aminoglycoside ototoxicity. Am J Otolaryngol. 1980 Feb; 1(2):169-79.
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Isolation of two proteins with 9-ketoprostaglandin reductase and NADP-linked 15-hydroxyprostaglandin dehydrogenase activities and studies on their inhibition. Biochem Biophys Res Commun. 1978 Apr 28; 81(4):1227-34.