 Mitomycins
"Mitomycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.
| Descriptor ID |
D008937
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| MeSH Number(s) |
D02.806.400.249 D03.383.097.500 D03.438.473.412.249
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mitomycins".
Below are MeSH descriptors whose meaning is more specific than "Mitomycins".
This graph shows the total number of publications written about "Mitomycins" by people in this website by year, and whether "Mitomycins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1984 | 0 | 2 | 2 | | 1989 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mitomycins" by people in Profiles.
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Kharbanda S, Ren R, Pandey P, Shafman TD, Feller SM, Weichselbaum RR, Kufe DW. Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents. Nature. 1995 Aug 31; 376(6543):785-8.
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Schwartz JL, Karrison T, Le Beau MM, Larson RA, Sagher D, Strauss B, Rowley JD, Weichselbaum RR. Chromosomal sensitivity of lymphocytes from individuals with therapy-related acute nonlymphocytic leukemia. Mutat Res. 1989 Apr; 216(2):119-26.
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Rubin JS, Prideaux VR, Willard HF, Dulhanty AM, Whitmore GF, Bernstein A. Molecular cloning and chromosomal localization of DNA sequences associated with a human DNA repair gene. Mol Cell Biol. 1985 Feb; 5(2):398-405.
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Larson RA, Kluskens LE, Yachnin S. The DNA synthetic response of normal and abnormal human lymphocytes to mevalonic acid: the role of granulocytes as a helper population. J Allergy Clin Immunol. 1984 Sep; 74(3 Pt 1):280-90.
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Antel JP, Peeples DM, Reder AT, Arnason BG. Analysis of T regulator cell surface markers and functional properties in multiple sclerosis. J Neuroimmunol. 1984 Apr; 6(2):93-103.
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Little JB, Nove J, Weichselbaum RR. Abnormal sensitivity of diploid skin fibroblasts from a family with gardner's syndrome to the lethal effects of X-irradiation, ultraviolet light and mitomycin-C. Mutat Res. 1980 Apr; 70(2):241-50.
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Bitran JD, Desser RK, Kozloff MF, Billings AA, Shapiro CM. Treatment of metastatic pancreatic and gastric adenocarcinomas with 5-fluorouracil, adriamycin, and mitomycin C (FAM). Cancer Treat Rep. 1979 Nov-Dec; 63(11-12):2049-51.
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Fornace AJ, Little JB, Weichselbaum RR. DNA repair in a Fanconi's anemia fibroblast cell strain. Biochim Biophys Acta. 1979 Jan 26; 561(1):99-109.
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Shapiro JA. Observations on lysogeny in glutamic acid bacteria. Appl Environ Microbiol. 1976 Jul; 32(1):179-82.
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Shapiro JA, Dean DH, Halvorson HO. Low-frequency specialized transduction with Bacillus subtilis bacteriophage phi 105. Virology. 1974 Dec; 62(2):393-403.
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