Histone-Lysine N-Methyltransferase
"Histone-Lysine N-Methyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the methylation of the epsilon-amino group of lysine residues in proteins to yield epsilon mono-, di-, and trimethyllysine. EC 2.1.1.43.
| Descriptor ID |
D011495
|
| MeSH Number(s) |
D08.811.913.555.500.800.400
|
| Concept/Terms |
Histone-Lysine N-Methyltransferase- Histone-Lysine N-Methyltransferase
- Histone Lysine N Methyltransferase
- N-Methyltransferase, Histone-Lysine
- Protein Methylase III
- Histone-Lysine Methyltransferase
- Histone Lysine Methyltransferase
- Methyltransferase, Histone-Lysine
- Protein Lysine Methyltransferase
- Methyltransferase, Protein Lysine
- Protein Methyltransferase III
|
Below are MeSH descriptors whose meaning is more general than "Histone-Lysine N-Methyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Histone-Lysine N-Methyltransferase".
This graph shows the total number of publications written about "Histone-Lysine N-Methyltransferase" by people in this website by year, and whether "Histone-Lysine N-Methyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 3 | 3 |
| 1995 | 0 | 3 | 3 |
| 1996 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 7 | 8 |
| 2006 | 2 | 1 | 3 |
| 2007 | 2 | 2 | 4 |
| 2008 | 1 | 3 | 4 |
| 2009 | 2 | 3 | 5 |
| 2010 | 2 | 2 | 4 |
| 2011 | 5 | 2 | 7 |
| 2012 | 5 | 5 | 10 |
| 2013 | 2 | 2 | 4 |
| 2014 | 4 | 2 | 6 |
| 2015 | 7 | 3 | 10 |
| 2016 | 11 | 0 | 11 |
| 2017 | 7 | 2 | 9 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 4 | 1 | 5 |
| 2021 | 2 | 1 | 3 |
| 2022 | 2 | 0 | 2 |
| 2023 | 3 | 0 | 3 |
| 2024 | 3 | 1 | 4 |
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Below are the most recent publications written about "Histone-Lysine N-Methyltransferase" by people in Profiles.
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Gene regulatory network inference from CRISPR perturbations in primary CD4+ T cells elucidates the genomic basis of immune disease. Cell Genom. 2024 Nov 13; 4(11):100671.
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NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis. Nat Genet. 2024 Oct; 56(10):2132-2143.
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Discovery of LLC0424 as a Potent and Selective in Vivo NSD2 PROTAC Degrader. J Med Chem. 2024 May 09; 67(9):6938-6951.
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Patterns of recombination in snakes reveal a tug-of-war between PRDM9 and promoter-like features. Science. 2024 Feb 23; 383(6685):eadj7026.
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Down the Penrose stairs, or how selection for fewer recombination hotspots maintains their existence. Elife. 2023 Oct 13; 12.
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SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck. Cell Rep. 2023 07 25; 42(7):112823.
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The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia. Nature. 2023 03; 615(7954):920-924.
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The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors. Cell Mol Life Sci. 2022 May 09; 79(6):285.
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PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2. Proc Natl Acad Sci U S A. 2022 03 01; 119(9).
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Non-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia. Elife. 2021 07 15; 10.