 Retinoblastoma
"Retinoblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Descriptor ID |
D012175
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| MeSH Number(s) |
C04.557.465.625.600.725 C04.557.470.670.725 C04.557.580.625.600.725 C04.588.364.818.760 C11.319.475.760 C11.768.717.760
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| Concept/Terms |
Retinoblastoma- Retinoblastoma
- Retinoblastomas
- Glioblastoma, Retinal
- Glioblastomas, Retinal
- Retinal Glioblastoma
- Retinal Glioblastomas
- Neuroblastoma, Retinal
- Neuroblastomas, Retinal
- Retinal Neuroblastoma
- Retinal Neuroblastomas
- Eye Cancer, Retinoblastoma
- Glioma, Retinal
- Gliomas, Retinal
- Retinal Glioma
- Retinal Gliomas
Sporadic Retinoblastoma- Sporadic Retinoblastoma
- Retinoblastoma, Sporadic
- Retinoblastomas, Sporadic
- Sporadic Retinoblastomas
Familial Retinoblastoma- Familial Retinoblastoma
- Familial Retinoblastomas
- Retinoblastoma, Familial
- Retinoblastomas, Familial
- Hereditary Retinoblastoma
- Hereditary Retinoblastomas
- Retinoblastoma, Hereditary
- Retinoblastomas, Hereditary
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Below are MeSH descriptors whose meaning is more general than "Retinoblastoma".
Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma".
This graph shows the total number of publications written about "Retinoblastoma" by people in this website by year, and whether "Retinoblastoma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 3 | 1 | 4 | | 1983 | 2 | 0 | 2 | | 1984 | 2 | 0 | 2 | | 1985 | 1 | 0 | 1 | | 1986 | 2 | 0 | 2 | | 1988 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Retinoblastoma" by people in Profiles.
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Hiasat JG, Saleh A, Al-Hussaini M, Al Nawaiseh I, Mehyar M, Qandeel M, Mohammad M, Deebajah R, Sultan I, Jaradat I, Mansour A, Yousef YA. The predictive value of magnetic resonance imaging of retinoblastoma for the likelihood of high-risk pathologic features. Eur J Ophthalmol. 2019 Mar; 29(2):262-268.
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Montague G, Cipriani N, Naclerio RM. A Rapidly Enlarging Forehead Mass in a Young Retinoblastoma Survivor. JAMA Otolaryngol Head Neck Surg. 2016 06 01; 142(6):597-8.
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Silva AK, Yi H, Hayes SH, Seigel GM, Hackam AS. Lithium chloride regulates the proliferation of stem-like cells in retinoblastoma cell lines: a potential role for the canonical Wnt signaling pathway. Mol Vis. 2010 Jan 13; 16:36-45.
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Du W, Searle JS. The rb pathway and cancer therapeutics. Curr Drug Targets. 2009 Jul; 10(7):581-9.
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Zage PE, Reitman AJ, Seshadri R, Weinstein JL, Mets MB, Zeid JL, Greenwald MJ, Strauss LC, Goldman S. Outcomes of a two-drug chemotherapy regimen for intraocular retinoblastoma. Pediatr Blood Cancer. 2008 Mar; 50(3):567-72.
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Gombos DS, Hungerford J, Abramson DH, Kingston J, Chantada G, Dunkel IJ, Antoneli CB, Greenwald M, Haik BG, Leal CA, Medina-Sanson A, Schefler AC, Veerakul G, Wieland R, Bornfeld N, Wilson MW, Yu CB. Secondary acute myelogenous leukemia in patients with retinoblastoma: is chemotherapy a factor? Ophthalmology. 2007 Jul; 114(7):1378-83.
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Du W, Pogoriler J. Retinoblastoma family genes. Oncogene. 2006 Aug 28; 25(38):5190-200.
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Koshy M, Paulino AC, Mai WY, Teh BS. Radiation-induced osteosarcomas in the pediatric population. Int J Radiat Oncol Biol Phys. 2005 Nov 15; 63(4):1169-74.
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Girardet A, McPeek MS, Leeflang EP, Munier F, Arnheim N, Claustres M, Pellestor F. Meiotic segregation analysis of RB1 alleles in retinoblastoma pedigrees by use of single-sperm typing. Am J Hum Genet. 2000 Jan; 66(1):167-75.
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Fountain TR, Goldberger S, Murphree AL. Orbital development after enucleation in early childhood. Ophthalmic Plast Reconstr Surg. 1999 Jan; 15(1):32-6.
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