"Collagen Type IV" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules assemble to form a sheet-like network which is involved in maintaining the structural integrity of basement membranes. The predominant form of the protein is comprised of two alpha1(IV) subunits and one alpha2(IV) subunit, however, at least six different alpha subunits can be incorporated into the heterotrimer.
| Descriptor ID |
D024141
|
| MeSH Number(s) |
D12.776.860.300.250.400.100
|
| Concept/Terms |
Collagen Type IV- Collagen Type IV
- Type IV (Basement Membrane) Collagen
- Type IV Collagen
- Collagen, Type IV
|
Below are MeSH descriptors whose meaning is more general than "Collagen Type IV".
Below are MeSH descriptors whose meaning is more specific than "Collagen Type IV".
This graph shows the total number of publications written about "Collagen Type IV" by people in this website by year, and whether "Collagen Type IV" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Collagen Type IV" by people in Profiles.
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Differential expression of parietal epithelial cell and podocyte extracellular matrix proteins in focal segmental glomerulosclerosis and diabetic nephropathy. Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1680-F1694.
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Enterococcus faecalis exploits the human fibrinolytic system to drive excess collagenolysis: implications in gut healing and identification of druggable targets. Am J Physiol Gastrointest Liver Physiol. 2020 01 01; 318(1):G1-G9.
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Tissue Structure: A CIVICs Lesson for Adipocytes. Curr Biol. 2017 09 25; 27(18):R1013-R1015.
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ATP-citrate lyase is essential for high glucose-induced histone hyperacetylation and fibrogenic gene upregulation in mesangial cells. Am J Physiol Renal Physiol. 2017 Aug 01; 313(2):F423-F429.
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Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 06 01; 143(11):1958-70.
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The genetics of monarch butterfly migration and warning colouration. Nature. 2014 Oct 16; 514(7522):317-21.
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A Rab10-dependent mechanism for polarized basement membrane secretion during organ morphogenesis. Dev Cell. 2013 Jan 28; 24(2):159-68.
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Phase II, open-label study of brivanib as second-line therapy in patients with advanced hepatocellular carcinoma. Clin Cancer Res. 2012 Apr 01; 18(7):2090-8.
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COL4A1 mutations cause ocular dysgenesis, neuronal localization defects, and myopathy in mice and Walker-Warburg syndrome in humans. PLoS Genet. 2011 May; 7(5):e1002062.
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Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions. Proc Natl Acad Sci U S A. 2010 Jul 27; 107(30):13324-9.