"NF-kappa B p50 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p105 precursor protein and is capable of forming dimeric complexes with itself or with TRANSCRIPTION FACTOR RELA. It regulates expression of GENES involved in immune and inflammatory responses.
| Descriptor ID |
D052002
|
| MeSH Number(s) |
D12.776.260.600.124 D12.776.660.600.124 D12.776.930.600.124
|
| Concept/Terms |
NF-kappa B p50 Subunit- NF-kappa B p50 Subunit
- NF kappa B p50 Subunit
- NFKB1 Transcription Factor
- Transcription Factor, NFKB1
- NF-kappa B p50
- NF kappa B p50
- p50, NF-kappa B
- NF-kappaB 50-kDa
- NF kappaB 50 kDa
|
Below are MeSH descriptors whose meaning is more general than "NF-kappa B p50 Subunit".
Below are MeSH descriptors whose meaning is more specific than "NF-kappa B p50 Subunit".
This graph shows the total number of publications written about "NF-kappa B p50 Subunit" by people in this website by year, and whether "NF-kappa B p50 Subunit" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 3 | 0 | 3 |
| 2015 | 4 | 0 | 4 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "NF-kappa B p50 Subunit" by people in Profiles.
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NF-?B: Governing Macrophages in Cancer. Genes (Basel). 2024 01 31; 15(2).
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Pseudocell Tracer-A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination. PLoS Comput Biol. 2021 05; 17(5):e1008094.
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p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability. Nat Commun. 2020 10 06; 11(1):5007.
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High-throughput characterization of genetic effects on DNA-protein binding and gene transcription. Genome Res. 2018 11; 28(11):1701-1708.
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Co-stimulatory CD28 and transcription factor NFKB1 gene variants affect idiopathic recurrent miscarriages. J Hum Genet. 2016 Dec; 61(12):1035-1041.
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Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide. Cancer Res. 2015 May 15; 75(10):2039-48.
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Peripheral blood IRF1 expression as a marker for glucocorticoid sensitivity. Pharmacogenet Genomics. 2015 Mar; 25(3):126-33.
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Nfkb1/p50 and mammalian aging. Oncotarget. 2015 Feb 28; 6(6):3471-2.
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S-phase-dependent p50/NF-?B1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability. Cell Cycle. 2015; 14(4):566-76.
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Loss of Nfkb1 leads to early onset aging. Aging (Albany NY). 2014 Nov; 6(11):931-43.