"Apolipoprotein C-II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB.
Descriptor ID |
D053304
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MeSH Number(s) |
D10.532.091.400.750 D12.776.070.400.400.750 D12.776.521.120.400.750
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Concept/Terms |
Apolipoprotein C-II- Apolipoprotein C-II
- Apolipoprotein C II
- Apoprotein C-II
- Apoprotein C II
- Apolipoprotein C-2
- Apolipoprotein C 2
- Apolipoprotein CII
- Apo C-II
- Apo C II
- ApoC2
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Below are MeSH descriptors whose meaning is more general than "Apolipoprotein C-II".
Below are MeSH descriptors whose meaning is more specific than "Apolipoprotein C-II".
This graph shows the total number of publications written about "Apolipoprotein C-II" by people in this website by year, and whether "Apolipoprotein C-II" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Apolipoprotein C-II" by people in Profiles.
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A dual apolipoprotein C-II mimetic-apolipoprotein C-III antagonist peptide lowers plasma triglycerides. Sci Transl Med. 2020 01 29; 12(528).
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A cross-sectional study of lipids and ApoC levels in Alzheimer's patients with and without cardiovascular disease. J Gerontol A Biol Sci Med Sci. 2002 Nov; 57(11):M757-61.