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Jean-Luc Benoit

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Infectious Diseases
AddressChicago IL 60637
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ridgway JP, Farley B, Benoit JL, Frohne C, Hazra A, Pettit N, Pho M, Pursell K, Saltzman J, Schmitt J, Uvin AZ, Pitrak D, McNulty M. A Case Series of Five People Living with HIV Hospitalized with COVID-19 in Chicago, Illinois. AIDS Patient Care STDS. 2020 08; 34(8):331-335. PMID: 32469614.
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    2. Micic D, Oto A, Charlton MR, Benoit JL, Siegler M. Hiding in the Water. N Engl J Med. 2020 May 07; 382(19):1844-1849. PMID: 32374966.
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    3. Ullio-Gamboa G, Palma S, Benoit JP, Allemandi D, Picollo MI, Toloza AC. Ivermectin lipid-based nanocarriers as novel formulations against head lice. Parasitol Res. 2017 Aug; 116(8):2111-2117. PMID: 28523490.
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    4. Le Roux G, Moche H, Nieto A, Benoit JP, Nesslany F, Lagarce F. Cytotoxicity and genotoxicity of lipid nanocapsules. Toxicol In Vitro. 2017 Jun; 41:189-199. PMID: 28323104.
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    5. Roger E, Gimel JC, Bensley C, Klymchenko AS, Benoit JP. Lipid nanocapsules maintain full integrity after crossing a human intestinal epithelium model. J Control Release. 2017 05 10; 253:11-18. PMID: 28274740.
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    6. Cieslak A, Wauthoz N, Nieto Orellana A, Lautram N, Béjaud J, Hureaux J, Lafleur M, Benoit JP, Salomon CJ, Bastiat G. Stealth nanocarriers based sterosomes using PEG post-insertion process. Eur J Pharm Biopharm. 2017 Jun; 115:31-38. PMID: 28216002.
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    7. Resnier P, Galopin N, Sibiril Y, Clavreul A, Cayon J, Briganti A, Legras P, Vessières A, Montier T, Jaouen G, Benoit JP, Passirani C. Efficient ferrocifen anticancer drug and Bcl-2 gene therapy using lipid nanocapsules on human melanoma xenograft in mouse. Pharmacol Res. 2017 Dec; 126:54-65. PMID: 28159700.
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    8. Benoit J, Manger PR, Rubidge BS. Palaeoneurological clues to the evolution of defining mammalian soft tissue traits. Sci Rep. 2016 05 09; 6:25604. PMID: 27157809.
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    9. Sasso MS, Lollo G, Pitorre M, Solito S, Pinton L, Valpione S, Bastiat G, Mandruzzato S, Bronte V, Marigo I, Benoit JP. Low dose gemcitabine-loaded lipid nanocapsules target monocytic myeloid-derived suppressor cells and potentiate cancer immunotherapy. Biomaterials. 2016 07; 96:47-62. PMID: 27135716.
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    10. Karageorgis A, Dufort S, Sancey L, Henry M, Hirsjärvi S, Passirani C, Benoit JP, Gravier J, Texier I, Montigon O, Benmerad M, Siroux V, Barbier EL, Coll JL. An MRI-based classification scheme to predict passive access of 5 to 50-nm large nanoparticles to tumors. Sci Rep. 2016 Feb 19; 6:21417. PMID: 26892874.
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    11. Gamboa GV, Palma SD, Lifschitz A, Ballent M, Lanusse C, Passirani C, Benoit JP, Allemandi DA. Ivermectin-loaded lipid nanocapsules: toward the development of a new antiparasitic delivery system for veterinary applications. Parasitol Res. 2016 May; 115(5):1945-53. PMID: 26852126.
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    12. Pettit NN, Alonso V, Wojcik E, Anyanwu EC, Ebara L, Benoit JL. Possible serotonin syndrome with carbidopa-levodopa and linezolid. J Clin Pharm Ther. 2016 Feb; 41(1):101-3. PMID: 26813986.
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    13. Simonsson C, Bastiat G, Pitorre M, Klymchenko AS, Béjaud J, Mély Y, Benoit JP. Inter-nanocarrier and nanocarrier-to-cell transfer assays demonstrate the risk of an immediate unloading of dye from labeled lipid nanocapsules. Eur J Pharm Biopharm. 2016 Jan; 98:47-56. PMID: 26522878.
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    14. Lollo G, Vincent M, Ullio-Gamboa G, Lemaire L, Franconi F, Couez D, Benoit JP. Development of multifunctional lipid nanocapsules for the co-delivery of paclitaxel and CpG-ODN in the treatment of glioblastoma. Int J Pharm. 2015 Nov 30; 495(2):972-80. PMID: 26428632.
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    15. Pensel PE, Ullio Gamboa G, Fabbri J, Ceballos L, Sanchez Bruni S, Alvarez LI, Allemandi D, Benoit JP, Palma SD, Elissondo MC. Cystic echinococcosis therapy: Albendazole-loaded lipid nanocapsules enhance the oral bioavailability and efficacy in experimentally infected mice. Acta Trop. 2015 Dec; 152:185-194. PMID: 26409727.
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    16. Bussard D, Harf A, Sibeoni J, Radjack R, Benoit JP, Moro MR. [The parents' experience of school refusal in adolescence]. Soins Pediatr Pueric. 2015 Sep-Oct; (286):31-6. PMID: 26381070.
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    17. Wauthoz N, Bastiat G, Moysan E, Cieslak A, Kondo K, Zandecki M, Moal V, Rousselet MC, Hureaux J, Benoit JP. Safe lipid nanocapsule-based gel technology to target lymph nodes and combat mediastinal metastases from an orthotopic non-small-cell lung cancer model in SCID-CB17 mice. Nanomedicine. 2015 Jul; 11(5):1237-45. PMID: 25791812.
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    18. Groo AC, Bossiere M, Trichard L, Legras P, Benoit JP, Lagarce F. In vivo evaluation of paclitaxel-loaded lipid nanocapsules after intravenous and oral administration on resistant tumor. Nanomedicine (Lond). 2015 Mar; 10(4):589-601. PMID: 25723092.
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    19. Danhier F, Messaoudi K, Lemaire L, Benoit JP, Lagarce F. Combined anti-Galectin-1 and anti-EGFR siRNA-loaded chitosan-lipid nanocapsules decrease temozolomide resistance in glioblastoma: in vivo evaluation. Int J Pharm. 2015 Mar 15; 481(1-2):154-61. PMID: 25644286.
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    20. Resnier P, LeQuinio P, Lautram N, André E, Gaillard C, Bastiat G, Benoit JP, Passirani C. Efficient in vitro gene therapy with PEG siRNA lipid nanocapsules for passive targeting strategy in melanoma. Biotechnol J. 2014 Nov; 9(11):1389-401. PMID: 25262914.
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    21. Pensel PE, Albani C, Gamboa GU, Benoit JP, Elissondo MC. In vitro effect of 5-fluorouracil and paclitaxel on Echinococcus granulosus larvae and cells. Acta Trop. 2014 Dec; 140:1-9. PMID: 25088684.
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    22. Lainé AL, Gravier J, Henry M, Sancey L, Béjaud J, Pancani E, Wiber M, Texier I, Coll JL, Benoit JP, Passirani C. Conventional versus stealth lipid nanoparticles: formulation and in vivo fate prediction through FRET monitoring. J Control Release. 2014 Aug 28; 188:1-8. PMID: 24878182.
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    23. Lainé AL, Clavreul A, Rousseau A, Tétaud C, Vessieres A, Garcion E, Jaouen G, Aubert L, Guilbert M, Benoit JP, Toillon RA, Passirani C. Inhibition of ectopic glioma tumor growth by a potent ferrocenyl drug loaded into stealth lipid nanocapsules. Nanomedicine. 2014 Nov; 10(8):1667-77. PMID: 24842766.
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    24. Cui ZK, Edwards K, Nieto Orellana A, Bastiat G, Benoit JP, Lafleur M. Impact of interfacial cholesterol-anchored polyethylene glycol on sterol-rich non-phospholipid liposomes. J Colloid Interface Sci. 2014 Aug 15; 428:111-20. PMID: 24910042.
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    25. Messaoudi K, Saulnier P, Boesen K, Benoit JP, Lagarce F. Anti-epidermal growth factor receptor siRNA carried by chitosan-transacylated lipid nanocapsules increases sensitivity of glioblastoma cells to temozolomide. Int J Nanomedicine. 2014; 9:1479-90. PMID: 24711698.
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    26. Moysan E, González-Fernández Y, Lautram N, Béjaud J, Bastiat G, Benoit JP. An innovative hydrogel of gemcitabine-loaded lipid nanocapsules: when the drug is a key player of the nanomedicine structure. Soft Matter. 2014 Mar 21; 10(11):1767-77. PMID: 24652455.
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    27. Trotier-Faurion A, Passirani C, Béjaud J, Dézard S, Valayannopoulos V, Taran F, de Lonlay P, Benoit JP, Mabondzo A. Dodecyl creatine ester and lipid nanocapsule: a double strategy for the treatment of creatine transporter deficiency. Nanomedicine (Lond). 2015 Jan; 10(2):185-91. PMID: 24559037.
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    28. Lollo G, Rivera-Rodriguez GR, Bejaud J, Montier T, Passirani C, Benoit JP, García-Fuentes M, Alonso MJ, Torres D. Polyglutamic acid-PEG nanocapsules as long circulating carriers for the delivery of docetaxel. Eur J Pharm Biopharm. 2014 May; 87(1):47-54. PMID: 24530693.
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    29. Hirsjärvi S, Belloche C, Hindré F, Garcion E, Benoit JP. Tumour targeting of lipid nanocapsules grafted with cRGD peptides. Eur J Pharm Biopharm. 2014 May; 87(1):152-9. PMID: 24361535.
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    30. Groo AC, Saulnier P, Gimel JC, Gravier J, Ailhas C, Benoit JP, Lagarce F. Fate of paclitaxel lipid nanocapsules in intestinal mucus in view of their oral delivery. Int J Nanomedicine. 2013; 8:4291-302. PMID: 24235827.
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    31. Rivera-Rodriguez GR, Lollo G, Montier T, Benoit JP, Passirani C, Alonso MJ, Torres D. In vivo evaluation of poly-l-asparagine nanocapsules as carriers for anti-cancer drug delivery. Int J Pharm. 2013 Dec 15; 458(1):83-9. PMID: 24140546.
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    32. Saliou B, Thomas O, Lautram N, Clavreul A, Hureaux J, Urban T, Benoit JP, Lagarce F. Development and in vitro evaluation of a novel lipid nanocapsule formulation of etoposide. Eur J Pharm Sci. 2013 Oct 09; 50(2):172-80. PMID: 23831519.
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    33. Bastiat G, Pritz CO, Roider C, Fouchet F, Lignières E, Jesacher A, Glueckert R, Ritsch-Marte M, Schrott-Fischer A, Saulnier P, Benoit JP. A new tool to ensure the fluorescent dye labeling stability of nanocarriers: a real challenge for fluorescence imaging. J Control Release. 2013 Sep 28; 170(3):334-42. PMID: 23792117.
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    34. Weyland M, Griveau A, Bejaud J, Benoit JP, Coursaget P, Garcion E. Lipid nanocapsule functionalization by lipopeptides derived from human papillomavirus type-16 capsid for nucleic acid delivery into cancer cells. Int J Pharm. 2013 Oct 01; 454(2):756-64. PMID: 23769994.
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    35. Resnier P, Montier T, Mathieu V, Benoit JP, Passirani C. A review of the current status of siRNA nanomedicines in the treatment of cancer. Biomaterials. 2013 Sep; 34(27):6429-43. PMID: 23727262.
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    36. Resnier P, David S, Lautram N, Delcroix GJ, Clavreul A, Benoit JP, Passirani C. EGFR siRNA lipid nanocapsules efficiently transfect glioma cells in vitro. Int J Pharm. 2013 Oct 01; 454(2):748-55. PMID: 23583841.
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    37. Benoit JP. [Conception and studies of micro and nanomedicines for brain applications]. Biol Aujourdhui. 2012; 206(4):263-71. PMID: 23419253.
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    38. Balzeau J, Pinier M, Berges R, Saulnier P, Benoit JP, Eyer J. The effect of functionalizing lipid nanocapsules with NFL-TBS.40-63 peptide on their uptake by glioblastoma cells. Biomaterials. 2013 Apr; 34(13):3381-9. PMID: 23391494.
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    39. Lemaire L, Bastiat G, Franconi F, Lautram N, Duong Thi Dan T, Garcion E, Saulnier P, Benoit JP. Perfluorocarbon-loaded lipid nanocapsules as oxygen sensors for tumor tissue pO2 assessment. Eur J Pharm Biopharm. 2013 Aug; 84(3):479-86. PMID: 23352843.
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    40. David S, Passirani C, Carmoy N, Morille M, Mevel M, Chatin B, Benoit JP, Montier T, Pitard B. DNA nanocarriers for systemic administration: characterization and in vivo bioimaging in healthy mice. Mol Ther Nucleic Acids. 2013 Jan 08; 2:e64. PMID: 23299832.
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    41. Vrignaud S, Anton N, Passirani C, Benoit JP, Saulnier P. Aqueous core nanocapsules: a new solution for encapsulating doxorubicin hydrochloride. Drug Dev Ind Pharm. 2013 Nov; 39(11):1706-11. PMID: 23289391.
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    42. David S, Montier T, Carmoy N, Resnier P, Clavreul A, Mével M, Pitard B, Benoit JP, Passirani C. Treatment efficacy of DNA lipid nanocapsules and DNA multimodular systems after systemic administration in a human glioma model. J Gene Med. 2012 Dec; 14(12):769-75. PMID: 23143656.
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    43. Moysan E, Bastiat G, Benoit JP. Gemcitabine versus Modified Gemcitabine: a review of several promising chemical modifications. Mol Pharm. 2013 Feb 04; 10(2):430-44. PMID: 22978251.
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    44. Cajot S, Van Butsele K, Paillard A, Passirani C, Garcion E, Benoit JP, Varshney SK, Jérôme C. Smart nanocarriers for pH-triggered targeting and release of hydrophobic drugs. Acta Biomater. 2012 Dec; 8(12):4215-23. PMID: 22963850.
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    45. Hirsjärvi S, Dufort S, Gravier J, Texier I, Yan Q, Bibette J, Sancey L, Josserand V, Passirani C, Benoit JP, Coll JL. Influence of size, surface coating and fine chemical composition on the in vitro reactivity and in vivo biodistribution of lipid nanocapsules versus lipid nanoemulsions in cancer models. Nanomedicine. 2013 Apr; 9(3):375-87. PMID: 22960195.
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    46. Cosson MA, Bertrand JB, Martin C, Veziris N, Picard C, Goulvestre C, Coignard S, Benoit JP, Silvera S, Moro MR, Poyart C, Morand PC. Temporal interferon-gamma release response to Mycobacterium kansasii infection in an anorexia nervosa patient. J Med Microbiol. 2012 Nov; 61(Pt 11):1617-1620. PMID: 22859583.
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    47. Vrignaud S, Hureaux J, Wack S, Benoit JP, Saulnier P. Design, optimization and in vitro evaluation of reverse micelle-loaded lipid nanocarriers containing erlotinib hydrochloride. Int J Pharm. 2012 Oct 15; 436(1-2):194-200. PMID: 22721853.
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    48. Laine AL, Huynh NT, Clavreul A, Balzeau J, Béjaud J, Vessieres A, Benoit JP, Eyer J, Passirani C. Brain tumour targeting strategies via coated ferrociphenol lipid nanocapsules. Eur J Pharm Biopharm. 2012 Aug; 81(3):690-3. PMID: 22561953.
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    49. David S, Resnier P, Guillot A, Pitard B, Benoit JP, Passirani C. siRNA LNCs--a novel platform of lipid nanocapsules for systemic siRNA administration. Eur J Pharm Biopharm. 2012 Jun; 81(2):448-52. PMID: 22381204.
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    50. Basile L, Passirani C, Huynh NT, Béjaud J, Benoit JP, Puglisi G, Pignatello R. Serum-stable, long-circulating paclitaxel-loaded colloidal carriers decorated with a new amphiphilic PEG derivative. Int J Pharm. 2012 Apr 15; 426(1-2):231-238. PMID: 22306040.
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    51. Chang J, Paillard A, Passirani C, Morille M, Benoit JP, Betbeder D, Garcion E. Transferrin adsorption onto PLGA nanoparticles governs their interaction with biological systems from blood circulation to brain cancer cells. Pharm Res. 2012 Jun; 29(6):1495-505. PMID: 22167349.
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    52. Bourseau-Guilmain E, Lemaire L, Griveau A, Hervouet E, Vallette F, Berger F, Menei P, Benoit JP, Wion D, Garcion E. In vitro expansion of human glioblastoma cells at non-physiological oxygen tension irreversibly alters subsequent in vivo aggressiveness and AC133 expression. Int J Oncol. 2012 Apr; 40(4):1220-9. PMID: 22134773.
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    53. Ramadan A, Lagarce F, Tessier-Marteau A, Thomas O, Legras P, Macchi L, Saulnier P, Benoit JP. Oral fondaparinux: use of lipid nanocapsules as nanocarriers and in vivo pharmacokinetic study. Int J Nanomedicine. 2011; 6:2941-51. PMID: 22162653.
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    54. Bourseau-Guilmain E, Griveau A, Benoit JP, Garcion E. The importance of the stem cell marker prominin-1/CD133 in the uptake of transferrin and in iron metabolism in human colon cancer Caco-2 cells. PLoS One. 2011; 6(9):e25515. PMID: 21966538.
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    55. Hirsjärvi S, Passirani C, Benoit JP. Passive and active tumour targeting with nanocarriers. Curr Drug Discov Technol. 2011 Sep; 8(3):188-96. PMID: 21513482.
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    56. Vrignaud S, Benoit JP, Saulnier P. Strategies for the nanoencapsulation of hydrophilic molecules in polymer-based nanoparticles. Biomaterials. 2011 Nov; 32(33):8593-604. PMID: 21831421.
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    57. Lacoeuille F, Hindré F, Venier-Julienne MC, Sergent M, Bouchet F, Jouaneton S, Denizot B, Askienazy S, Benoit JP, Couturier OF, Le Jeune JJ. A starch-based microparticulate system dedicated to diagnostic and therapeutic nuclear medicine applications. Biomaterials. 2011 Nov; 32(31):7999-8009. PMID: 21788070.
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    58. David S, Carmoy N, Resnier P, Denis C, Misery L, Pitard B, Benoit JP, Passirani C, Montier T. In vivo imaging of DNA lipid nanocapsules after systemic administration in a melanoma mouse model. Int J Pharm. 2012 Feb 14; 423(1):108-15. PMID: 21726617.
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    59. Huynh NT, Morille M, Bejaud J, Legras P, Vessieres A, Jaouen G, Benoit JP, Passirani C. Treatment of 9L gliosarcoma in rats by ferrociphenol-loaded lipid nanocapsules based on a passive targeting strategy via the EPR effect. Pharm Res. 2011 Dec; 28(12):3189-98. PMID: 21691892.
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    60. Van Butsele K, Morille M, Passirani C, Legras P, Benoit JP, Varshney SK, Jérôme R, Jérôme C. Stealth properties of poly(ethylene oxide)-based triblock copolymer micelles: a prerequisite for a pH-triggered targeting system. Acta Biomater. 2011 Oct; 7(10):3700-7. PMID: 21704739.
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    61. Bourseau-Guilmain E, Béjaud J, Griveau A, Lautram N, Hindré F, Weyland M, Benoit JP, Garcion E. Development and characterization of immuno-nanocarriers targeting the cancer stem cell marker AC133. Int J Pharm. 2012 Feb 14; 423(1):93-101. PMID: 21683129.
      View in: PubMed
    62. Huynh NT, Passirani C, Allard-Vannier E, Lemaire L, Roux J, Garcion E, Vessieres A, Benoit JP. Administration-dependent efficacy of ferrociphenol lipid nanocapsules for the treatment of intracranial 9L rat gliosarcoma. Int J Pharm. 2012 Feb 14; 423(1):55-62. PMID: 21536115.
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    63. Vrignaud S, Anton N, Gayet P, Benoit JP, Saulnier P. Reverse micelle-loaded lipid nanocarriers: a novel drug delivery system for the sustained release of doxorubicin hydrochloride. Eur J Pharm Biopharm. 2011 Sep; 79(1):197-204. PMID: 21345371.
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    64. Roger E, Lagarce F, Benoit JP. Development and characterization of a novel lipid nanocapsule formulation of Sn38 for oral administration. Eur J Pharm Biopharm. 2011 Sep; 79(1):181-8. PMID: 21303693.
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    65. Morille M, Passirani C, Dufort S, Bastiat G, Pitard B, Coll JL, Benoit JP. Tumor transfection after systemic injection of DNA lipid nanocapsules. Biomaterials. 2011 Mar; 32(9):2327-33. PMID: 21185595.
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    66. Weyland M, Manero F, Paillard A, Grée D, Viault G, Jarnet D, Menei P, Juin P, Chourpa I, Benoit JP, Grée R, Garcion E. Mitochondrial targeting by use of lipid nanocapsules loaded with SV30, an analogue of the small-molecule Bcl-2 inhibitor HA14-1. J Control Release. 2011 Apr 10; 151(1):74-82. PMID: 21138749.
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    67. Cirpanli Y, Allard E, Passirani C, Bilensoy E, Lemaire L, Calis S, Benoit JP. Antitumoral activity of camptothecin-loaded nanoparticles in 9L rat glioma model. Int J Pharm. 2011 Jan 17; 403(1-2):201-6. PMID: 20951783.
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    68. Vinchon-Petit S, Jarnet D, Michalak S, Lewis A, Benoit JP, Menei P. Local implantation of doxorubicin drug eluting beads in rat glioma. Int J Pharm. 2010 Dec 15; 402(1-2):184-9. PMID: 20863875.
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    69. Anton N, Mojzisova H, Porcher E, Benoit JP, Saulnier P. Reverse micelle-loaded lipid nano-emulsions: new technology for nano-encapsulation of hydrophilic materials. Int J Pharm. 2010 Oct 15; 398(1-2):204-9. PMID: 20674723.
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    70. Hirsjärvi S, Qiao Y, Royere A, Bibette J, Benoit JP. Layer-by-layer surface modification of lipid nanocapsules. Eur J Pharm Biopharm. 2010 Oct; 76(2):200-7. PMID: 20656028.
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    71. Paillard A, Hindré F, Vignes-Colombeix C, Benoit JP, Garcion E. The importance of endo-lysosomal escape with lipid nanocapsules for drug subcellular bioavailability. Biomaterials. 2010 Oct; 31(29):7542-54. PMID: 20630585.
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    72. Benoit J, Tolédano C, Tiev KP, Gain M, Josselin-Mahr L, Cabane J, Kettaneh A. [Nail abnormality]. Rev Med Interne. 2011 Feb; 32(2):118-9. PMID: 20538387.
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    73. Roger E, Lagarce F, Garcion E, Benoit JP. Reciprocal competition between lipid nanocapsules and P-gp for paclitaxel transport across Caco-2 cells. Eur J Pharm Sci. 2010 Aug 11; 40(5):422-9. PMID: 20438839.
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    74. Hureaux J, Lagarce F, Gagnadoux F, Rousselet MC, Moal V, Urban T, Benoit JP. Toxicological study and efficacy of blank and paclitaxel-loaded lipid nanocapsules after i.v. administration in mice. Pharm Res. 2010 Mar; 27(3):421-30. PMID: 20054705.
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    75. Roger E, Lagarce F, Garcion E, Benoit JP. Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery. Nanomedicine (Lond). 2010 Feb; 5(2):287-306. PMID: 20148639.
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    76. Lacoeuille F, Hindré F, Denizot B, Bouchet F, Legras P, Couturier O, Askiénazy S, Benoit JP, Le Jeune JJ. New starch-based radiotracer for lung perfusion scintigraphy. Eur J Nucl Med Mol Imaging. 2010 Jan; 37(1):146-55. PMID: 19662407.
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    77. Delcroix GJ, Schiller PC, Benoit JP, Montero-Menei CN. Adult cell therapy for brain neuronal damages and the role of tissue engineering. Biomaterials. 2010 Mar; 31(8):2105-20. PMID: 20005569.
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    78. Allard E, Jarnet D, Vessières A, Vinchon-Petit S, Jaouen G, Benoit JP, Passirani C. Local delivery of ferrociphenol lipid nanocapsules followed by external radiotherapy as a synergistic treatment against intracranial 9L glioma xenograft. Pharm Res. 2010 Jan; 27(1):56-64. PMID: 19908129.
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    79. Anton N, Saulnier P, Gaillard C, Porcher E, Vrignaud S, Benoit JP. Aqueous-core lipid nanocapsules for encapsulating fragile hydrophilic and/or lipophilic molecules. Langmuir. 2009 Oct 06; 25(19):11413-9. PMID: 19788211.
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    80. Vinchon-Petit S, Jarnet D, Paillard A, Benoit JP, Garcion E, Menei P. In vivo evaluation of intracellular drug-nanocarriers infused into intracranial tumours by convection-enhanced delivery: distribution and radiosensitisation efficacy. J Neurooncol. 2010 Apr; 97(2):195-205. PMID: 19768659.
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    81. Roger E, Lagarce F, Garcion E, Benoit JP. Lipid nanocarriers improve paclitaxel transport throughout human intestinal epithelial cells by using vesicle-mediated transcytosis. J Control Release. 2009 Dec 03; 140(2):174-81. PMID: 19699246.
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    82. Hureaux J, Lagarce F, Gagnadoux F, Vecellio L, Clavreul A, Roger E, Kempf M, Racineux JL, Diot P, Benoit JP, Urban T. Lipid nanocapsules: ready-to-use nanovectors for the aerosol delivery of paclitaxel. Eur J Pharm Biopharm. 2009 Oct; 73(2):239-46. PMID: 19560538.
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    83. Roger E, Lagarce F, Benoit JP. The gastrointestinal stability of lipid nanocapsules. Int J Pharm. 2009 Sep 11; 379(2):260-5. PMID: 19524655.
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    84. Morille M, Passirani C, Letrou-Bonneval E, Benoit JP, Pitard B. Galactosylated DNA lipid nanocapsules for efficient hepatocyte targeting. Int J Pharm. 2009 Sep 11; 379(2):293-300. PMID: 19505548.
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    85. Hureaux J, Lagarce F, Gagnadoux F, Clavreul A, Benoit JP, Urban T. The adaptation of lipid nanocapsule formulations for blood administration in animals. Int J Pharm. 2009 Sep 11; 379(2):266-9. PMID: 19467305.
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    86. Allard E, Huynh NT, Vessières A, Pigeon P, Jaouen G, Benoit JP, Passirani C. Dose effect activity of ferrocifen-loaded lipid nanocapsules on a 9L-glioma model. Int J Pharm. 2009 Sep 11; 379(2):317-23. PMID: 19467309.
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    87. Huynh NT, Passirani C, Saulnier P, Benoit JP. Lipid nanocapsules: a new platform for nanomedicine. Int J Pharm. 2009 Sep 11; 379(2):201-9. PMID: 19409468.
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    88. Vonarbourg A, Passirani C, Desigaux L, Allard E, Saulnier P, Lambert O, Benoit JP, Pitard B. The encapsulation of DNA molecules within biomimetic lipid nanocapsules. Biomaterials. 2009 Jun; 30(18):3197-204. PMID: 19329183.
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    89. Allard E, Passirani C, Benoit JP. Convection-enhanced delivery of nanocarriers for the treatment of brain tumors. Biomaterials. 2009 Apr; 30(12):2302-18. PMID: 19168213.
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    90. Chapon C, Franconi F, Lacoeuille F, Hindré F, Saulnier P, Benoit JP, Le Jeune JJ, Lemaire L. Imaging E-selectin expression following traumatic brain injury in the rat using a targeted USPIO contrast agent. MAGMA. 2009 Jun; 22(3):167-74. PMID: 19107536.
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    91. Van Butsele K, Sibret P, Fustin CA, Gohy JF, Passirani C, Benoit JP, Jérôme R, Jérôme C. Synthesis and pH-dependent micellization of diblock copolymer mixtures. J Colloid Interface Sci. 2009 Jan 15; 329(2):235-43. PMID: 18930246.
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    92. Allard E, Passirani C, Garcion E, Pigeon P, Vessières A, Jaouen G, Benoit JP. Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas. J Control Release. 2008 Sep 10; 130(2):146-53. PMID: 18582507.
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    93. Petit S, Garcion E, Benoit JP, Menei P. [Local chemotherapy of malignant glioma: from syringe injections to nanotechnology]. Rev Neurol (Paris). 2008 Jun-Jul; 164(6-7):547-53. PMID: 18565353.
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    95. Morille M, Passirani C, Vonarbourg A, Clavreul A, Benoit JP. Progress in developing cationic vectors for non-viral systemic gene therapy against cancer. Biomaterials. 2008 Aug-Sep; 29(24-25):3477-96. PMID: 18499247.
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    96. Allard E, Hindre F, Passirani C, Lemaire L, Lepareur N, Noiret N, Menei P, Benoit JP. 188Re-loaded lipid nanocapsules as a promising radiopharmaceutical carrier for internal radiotherapy of malignant gliomas. Eur J Nucl Med Mol Imaging. 2008 Oct; 35(10):1838-46. PMID: 18465130.
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    97. Giteau A, Venier-Julienne MC, Marchal S, Courthaudon JL, Sergent M, Montero-Menei C, Verdier JM, Benoit JP. Reversible protein precipitation to ensure stability during encapsulation within PLGA microspheres. Eur J Pharm Biopharm. 2008 Sep; 70(1):127-36. PMID: 18448319.
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    98. Anton N, Benoit JP, Saulnier P. Design and production of nanoparticles formulated from nano-emulsion templates-a review. J Control Release. 2008 Jun 24; 128(3):185-99. PMID: 18374443.
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    99. Lacoeuille F, Garcion E, Benoit JP, Lamprecht A. Lipid nanocapsules for intracellular drug delivery of anticancer drugs. J Nanosci Nanotechnol. 2007 Dec; 7(12):4612-7. PMID: 18283853.
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    100. Giteau A, Venier-Julienne MC, Aubert-Pouëssel A, Benoit JP. How to achieve sustained and complete protein release from PLGA-based microparticles? Int J Pharm. 2008 Feb 28; 350(1-2):14-26. PMID: 18162341.
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    101. Béduneau A, Hindré F, Clavreul A, Leroux JC, Saulnier P, Benoit JP. Brain targeting using novel lipid nanovectors. J Control Release. 2008 Feb 18; 126(1):44-9. PMID: 18055056.
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    102. Béduneau A, Saulnier P, Benoit JP. Active targeting of brain tumors using nanocarriers. Biomaterials. 2007 Nov; 28(33):4947-67. PMID: 17716726.
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    103. Pasco A, Lemaire L, Franconi F, Lefur Y, Noury F, Saint-André JP, Benoit JP, Cozzone PJ, Le Jeune JJ. Perfusional deficit and the dynamics of cerebral edemas in experimental traumatic brain injury using perfusion and diffusion-weighted magnetic resonance imaging. J Neurotrauma. 2007 Aug; 24(8):1321-30. PMID: 17711393.
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    104. Anton N, Saulnier P, Boury F, Foussard F, Benoit JP, Proust JE. The influence of headgroup structure and fatty acyl chain saturation of phospholipids on monolayer behavior: a comparative rheological study. Chem Phys Lipids. 2007 Dec; 150(2):167-75. PMID: 17868664.
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    105. Lacoeuille F, Hindre F, Moal F, Roux J, Passirani C, Couturier O, Cales P, Le Jeune JJ, Lamprecht A, Benoit JP. In vivo evaluation of lipid nanocapsules as a promising colloidal carrier for paclitaxel. Int J Pharm. 2007 Nov 01; 344(1-2):143-9. PMID: 17646066.
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    106. Mladenovska K, Cruaud O, Richomme P, Belamie E, Raicki RS, Venier-Julienne MC, Popovski E, Benoit JP, Goracinova K. 5-ASA loaded chitosan-Ca-alginate microparticles: Preparation and physicochemical characterization. Int J Pharm. 2007 Dec 10; 345(1-2):59-69. PMID: 17616284.
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    107. Béduneau A, Saulnier P, Hindré F, Clavreul A, Leroux JC, Benoit JP. Design of targeted lipid nanocapsules by conjugation of whole antibodies and antibody Fab' fragments. Biomaterials. 2007 Nov; 28(33):4978-90. PMID: 17716725.
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    108. Anton N, Gayet P, Benoit JP, Saulnier P. Nano-emulsions and nanocapsules by the PIT method: an investigation on the role of the temperature cycling on the emulsion phase inversion. Int J Pharm. 2007 Nov 01; 344(1-2):44-52. PMID: 17592746.
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    109. Anton N, Saulnier P, Béduneau A, Benoit JP. Salting-out effect induced by temperature cycling on a water/nonionic surfactant/oil system. J Phys Chem B. 2007 Apr 12; 111(14):3651-7. PMID: 17388519.
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    110. Jestin E, Mougin-Degraef M, Faivre-Chauvet A, Remaud-Le Saëc P, Hindre F, Benoit JP, Chatal JF, Barbet J, Gestin JF. Radiolabeling and targeting of lipidic nanocapsules for applications in radioimmunotherapy. Q J Nucl Med Mol Imaging. 2007 Mar; 51(1):51-60. PMID: 17372573.
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    111. Mowat P, Franconi F, Chapon C, Lemaire L, Dorat J, Hindré F, Benoit JP, Richomme P, Le Jeune JJ. Evaluating SPIO-labelled cell MR efficiency by three-dimensional quantitative T2* MRI. NMR Biomed. 2007 Feb; 20(1):21-7. PMID: 16998951.
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    112. Tatard VM, Sindji L, Branton JG, Aubert-Pouëssel A, Colleau J, Benoit JP, Montero-Menei CN. Pharmacologically active microcarriers releasing glial cell line - derived neurotrophic factor: Survival and differentiation of embryonic dopaminergic neurons after grafting in hemiparkinsonian rats. Biomaterials. 2007 Apr; 28(11):1978-88. PMID: 17240442.
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    113. Sapin A, Clavreul A, Garcion E, Benoit JP, Menei P. Evaluation of particulate systems supporting tumor cell fractions in a preventive vaccination against intracranial rat glioma. J Neurosurg. 2006 Nov; 105(5):745-52. PMID: 17121138.
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    114. Vonarbourg A, Passirani C, Saulnier P, Simard P, Leroux JC, Benoit JP. Evaluation of pegylated lipid nanocapsules versus complement system activation and macrophage uptake. J Biomed Mater Res A. 2006 Sep 01; 78(3):620-8. PMID: 16779767.
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    115. Béduneau A, Saulnier P, Anton N, Hindré F, Passirani C, Rajerison H, Noiret N, Benoit JP. Pegylated nanocapsules produced by an organic solvent-free method: Evaluation of their stealth properties. Pharm Res. 2006 Sep; 23(9):2190-9. PMID: 16952009.
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    116. Fournier E, Passirani C, Colin N, Sagodira S, Menei P, Benoit JP, Montero-Menei CN. The brain tissue response to biodegradable poly(methylidene malonate 2.1.2)-based microspheres in the rat. Biomaterials. 2006 Oct; 27(28):4963-74. PMID: 16759690.
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    117. Vonarbourg A, Passirani C, Saulnier P, Benoit JP. Parameters influencing the stealthiness of colloidal drug delivery systems. Biomaterials. 2006 Aug; 27(24):4356-73. PMID: 16650890.
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    118. Lagarce F, Garcion E, Faisant N, Thomas O, Kanaujia P, Menei P, Benoit JP. Development and characterization of interleukin-18-loaded biodegradable microspheres. Int J Pharm. 2006 May 18; 314(2):179-88. PMID: 16515850.
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    119. Koennings S, Garcion E, Faisant N, Menei P, Benoit JP, Goepferich A. In vitro investigation of lipid implants as a controlled release system for interleukin-18. Int J Pharm. 2006 May 18; 314(2):145-52. PMID: 16513302.
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    120. Lamprecht A, Benoit JP. Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-glycoprotein inhibition. J Control Release. 2006 May 15; 112(2):208-13. PMID: 16574265.
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    121. Faisant N, Akiki J, Siepmann F, Benoit JP, Siepmann J. Effects of the type of release medium on drug release from PLGA-based microparticles: experiment and theory. Int J Pharm. 2006 May 18; 314(2):189-97. PMID: 16510257.
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    122. Elkharraz K, Faisant N, Guse C, Siepmann F, Arica-Yegin B, Oger JM, Gust R, Goepferich A, Benoit JP, Siepmann J. Paclitaxel-loaded microparticles and implants for the treatment of brain cancer: preparation and physicochemical characterization. Int J Pharm. 2006 May 18; 314(2):127-36. PMID: 16490330.
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    123. Layre A, Couvreur P, Chacun H, Richard J, Passirani C, Requier D, Benoit JP, Gref R. Novel composite core-shell nanoparticles as busulfan carriers. J Control Release. 2006 Apr 10; 111(3):271-80. PMID: 16488504.
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    124. Pasco A, Ter Minassian A, Chapon C, Lemaire L, Franconi F, Darabi D, Caron C, Benoit JP, Le Jeune JJ. Dynamics of cerebral edema and the apparent diffusion coefficient of water changes in patients with severe traumatic brain injury. A prospective MRI study. Eur Radiol. 2006 Jul; 16(7):1501-8. PMID: 16485132.
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    125. Ballot S, Noiret N, Hindré F, Denizot B, Garin E, Rajerison H, Benoit JP. 99mTc/188Re-labelled lipid nanocapsules as promising radiotracers for imaging and therapy: formulation and biodistribution. Eur J Nucl Med Mol Imaging. 2006 May; 33(5):602-7. PMID: 16450136.
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    126. Sapin A, Garcion E, Clavreul A, Lagarce F, Benoit JP, Menei P. Development of new polymer-based particulate systems for anti-glioma vaccination. Int J Pharm. 2006 Feb 17; 309(1-2):1-5. PMID: 16386390.
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    127. Andrieu-Soler C, Aubert-Pouëssel A, Doat M, Picaud S, Halhal M, Simonutti M, Venier-Julienne MC, Benoit JP, Behar-Cohen F. Intravitreous injection of PLGA microspheres encapsulating GDNF promotes the survival of photoreceptors in the rd1/rd1 mouse. Mol Vis. 2005 Nov 17; 11:1002-11. PMID: 16319820.
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    128. Pereira de Oliveira M, Garcion E, Venisse N, Benoit JP, Couet W, Olivier JC. Tissue distribution of indinavir administered as solid lipid nanocapsule formulation in mdr1a (+/+) and mdr1a (-/-) CF-1 mice. Pharm Res. 2005 Nov; 22(11):1898-1905. PMID: 16132350.
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    129. Motulsky A, Lafleur M, Couffin-Hoarau AC, Hoarau D, Boury F, Benoit JP, Leroux JC. Characterization and biocompatibility of organogels based on L-alanine for parenteral drug delivery implants. Biomaterials. 2005 Nov; 26(31):6242-53. PMID: 15916802.
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    130. Lagarce F, Faisant N, Desfontis JC, Marescaux L, Gautier F, Holopherne D, Rousselet MC, Menei P, Benoit JP. Biopharmaceutics of intrathecal baclofen-loaded microparticles in a goat model. Int J Pharm. 2005 Jul 14; 298(1):68-79. PMID: 15919163.
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    131. Garin E, Denizot B, Roux J, Noiret N, Lepareur N, Moreau M, Mesba H, Laurent JF, Herry JY, Bourguet P, Benoit JP, Lejeune JJ. Description and technical pitfalls of a hepatoma model and of intra-arterial injection of radiolabelled lipiodol in the rat. Lab Anim. 2005 Jul; 39(3):314-20. PMID: 16004691.
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    132. Lagarce F, Faisant N, Desfontis JC, Marescaux L, Gautier F, Richard J, Menei P, Benoit JP. Baclofen-loaded microspheres in gel suspensions for intrathecal drug delivery: in vitro and in vivo evaluation. Eur J Pharm Biopharm. 2005 Oct; 61(3):171-80. PMID: 15967653.
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    133. Garin E, Denizot B, Roux J, Noiret N, Lepareur N, Moreau M, Mesba A, Laurent JF, Herry JY, Bourguet P, Benoit JP, Lejeune JJ. Effect of stabilized iodized oil emulsion on experimentally induced hepatocellular carcinoma in rats. J Vasc Interv Radiol. 2005 Jun; 16(6):841-8. PMID: 15947048.
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    134. Vonarbourg A, Saulnier P, Passirani C, Benoit JP. Electrokinetic properties of noncharged lipid nanocapsules: influence of the dipolar distribution at the interface. Electrophoresis. 2005 Jun; 26(11):2066-75. PMID: 15852355.
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    135. Tatard VM, Venier-Julienne MC, Saulnier P, Prechter E, Benoit JP, Menei P, Montero-Menei CN. Pharmacologically active microcarriers: a tool for cell therapy. Biomaterials. 2005 Jun; 26(17):3727-37. PMID: 15621263.
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    136. Lagarce F, Renaud P, Faisant N, Nicolas G, Cailleux A, Richard J, Menei P, Benoit JP. Baclofen-loaded microspheres: preparation and efficacy testing in a new rabbit model. Eur J Pharm Biopharm. 2005 Apr; 59(3):449-59. PMID: 15760725.
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    137. Menei P, Montero-Menei C, Venier MC, Benoit JP. Drug delivery into the brain using poly(lactide-co-glycolide) microspheres. Expert Opin Drug Deliv. 2005 Mar; 2(2):363-76. PMID: 16296760.
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    138. Menei P, Capelle L, Guyotat J, Fuentes S, Assaker R, Bataille B, François P, Dorwling-Carter D, Paquis P, Bauchet L, Parker F, Sabatier J, Faisant N, Benoit JP. Local and sustained delivery of 5-fluorouracil from biodegradable microspheres for the radiosensitization of malignant glioma: a randomized phase II trial. Neurosurgery. 2005 Feb; 56(2):242-8; discussion 242-8. PMID: 15670372.
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    139. Tatard VM, Menei P, Benoit JP, Montero-Menei CN. Combining polymeric devices and stem cells for the treatment of neurological disorders: a promising therapeutic approach. Curr Drug Targets. 2005 Feb; 6(1):81-96. PMID: 15720216.
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    140. Garin E, Denizot B, Noiret N, Lepareur N, Roux J, Moreau M, Herry JY, Bourguet P, Benoit JP, Lejeune JJ. 188Re-SSS lipiodol: radiolabelling and biodistribution following injection into the hepatic artery of rats bearing hepatoma. Nucl Med Commun. 2004 Oct; 25(10):1007-13. PMID: 15381868.
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    141. Roullin VG, Mege M, Lemaire L, Cueyssac JP, Venier-Julienne MC, Menei P, Gamelin E, Benoit JP. Influence of 5-fluorouracil-loaded microsphere formulation on efficient rat glioma radiosensitization. Pharm Res. 2004 Sep; 21(9):1558-63. PMID: 15497679.
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    142. Lamprecht A, Saumet JL, Roux J, Benoit JP. Lipid nanocarriers as drug delivery system for ibuprofen in pain treatment. Int J Pharm. 2004 Jul 08; 278(2):407-14. PMID: 15196644.
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    143. Jollivet C, Montero-Menei CN, Venier-Julienne MC, Sapin A, Benoit JP, Menei P. Striatal tyrosine hydroxylase immunoreactive neurons are induced by L-dihydroxyphenylalanine and nerve growth factor treatment in 6-hydroxydopamine lesioned rats. Neurosci Lett. 2004 May 20; 362(2):79-82. PMID: 15193758.
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    144. Siepmann J, Faisant N, Akiki J, Richard J, Benoit JP. Effect of the size of biodegradable microparticles on drug release: experiment and theory. J Control Release. 2004 Apr 16; 96(1):123-34. PMID: 15063035.
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    145. Aubert-Pouëssel A, Venier-Julienne MC, Clavreul A, Sergent M, Jollivet C, Montero-Menei CN, Garcion E, Bibby DC, Menei P, Benoit JP. In vitro study of GDNF release from biodegradable PLGA microspheres. J Control Release. 2004 Mar 24; 95(3):463-75. PMID: 15023458.
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    146. Fournier E, Passirani C, Colin N, Breton P, Sagodira S, Benoit JP. Development of novel 5-FU-loaded poly(methylidene malonate 2.1.2)-based microspheres for the treatment of brain cancers. Eur J Pharm Biopharm. 2004 Mar; 57(2):189-97. PMID: 15018974.
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    147. Jollivet C, Aubert-Pouessel A, Clavreul A, Venier-Julienne MC, Montero-Menei CN, Benoit JP, Menei P. Long-term effect of intra-striatal glial cell line-derived neurotrophic factor-releasing microspheres in a partial rat model of Parkinson's disease. Neurosci Lett. 2004 Feb 19; 356(3):207-10. PMID: 15036631.
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    148. Roux E, Passirani C, Scheffold S, Benoit JP, Leroux JC. Serum-stable and long-circulating, PEGylated, pH-sensitive liposomes. J Control Release. 2004 Feb 10; 94(2-3):447-51. PMID: 14976960.
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    149. Rizk T, Montero-Menei C, Jollivet C, Benoit JP, Menei P. Pitfalls in the detection of lipid vectors in neural cell culture and in brain tissue. J Biomed Mater Res A. 2004 Feb 01; 68(2):360-4. PMID: 14704978.
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    150. Jollivet C, Aubert-Pouessel A, Clavreul A, Venier-Julienne MC, Remy S, Montero-Menei CN, Benoit JP, Menei P. Striatal implantation of GDNF releasing biodegradable microspheres promotes recovery of motor function in a partial model of Parkinson's disease. Biomaterials. 2004 Feb; 25(5):933-42. PMID: 14609682.
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    151. Menei P, Jadaud E, Faisant N, Boisdron-Celle M, Michalak S, Fournier D, Delhaye M, Benoit JP. Stereotaxic implantation of 5-fluorouracil-releasing microspheres in malignant glioma. Cancer. 2004 Jan 15; 100(2):405-10. PMID: 14716778.
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    152. Tatard VM, Venier-Julienne MC, Benoit JP, Menei P, Montero-Menei CN. In vivo evaluation of pharmacologically active microcarriers releasing nerve growth factor and conveying PC12 cells. Cell Transplant. 2004; 13(5):573-83. PMID: 15565869.
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    153. Fournier E, Passirani C, Vonarbourg A, Lemaire L, Colin N, Sagodira S, Menei P, Benoit JP. Therapeutic efficacy study of novel 5-FU-loaded PMM 2.1.2-based microspheres on C6 glioma. Int J Pharm. 2003 Dec 11; 268(1-2):31-5. PMID: 14643974.
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    154. Heurtault B, Saulnier P, Pech B, Proust JE, Benoit JP. Physico-chemical stability of colloidal lipid particles. Biomaterials. 2003 Oct; 24(23):4283-300. PMID: 12853260.
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    155. Faisant N, Siepmann J, Richard J, Benoit JP. Mathematical modeling of drug release from bioerodible microparticles: effect of gamma-irradiation. Eur J Pharm Biopharm. 2003 Sep; 56(2):271-9. PMID: 12957642.
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    156. Fournier E, Passirani C, Montero-Menei CN, Benoit JP. Biocompatibility of implantable synthetic polymeric drug carriers: focus on brain biocompatibility. Biomaterials. 2003 Aug; 24(19):3311-31. PMID: 12763459.
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    157. Fournier E, Passirani C, Montero-Menei C, Colin N, Breton P, Sagodira S, Menei P, Benoit JP. Therapeutic effectiveness of novel 5-fluorouracil-loaded poly(methylidene malonate 2.1.2)-based microspheres on F98 glioma-bearing rats. Cancer. 2003 Jun 01; 97(11):2822-9. PMID: 12767096.
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    158. Lamprecht A, Benoit JP. Simple liquid-chromatographic method for Nile Red quantification in cell culture in spite of photobleaching. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Apr 25; 787(2):415-9. PMID: 12650763.
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    159. Roullin VG, Lemaire L, Venier-Julienne MC, Faisant N, Franconi F, Benoit JP. Release kinetics of 5-fluorouracil-loaded microspheres on an experimental rat glioma. Anticancer Res. 2003 Jan-Feb; 23(1A):21-5. PMID: 12680190.
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    160. Thies C, Ribeiro Dos Santos I, Richard J, VandeVelde V, Rolland H, Benoit JP. A supercritical fluid-based coating technology 1: process considerations. J Microencapsul. 2003 Jan-Feb; 20(1):87-96. PMID: 12519704.
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    161. Ribeiro Dos Santos I, Thies C, Richard J, Le Meurlay D, Gajan V, VandeVelde V, Benoit JP. A supercritical fluid-based coating technology. 2: solubility considerations. J Microencapsul. 2003 Jan-Feb; 20(1):97-109. PMID: 12519705.
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    162. Ribeiro Dos Santos I, Richard J, Thies C, Pech B, Benoit JP. A supercritical fluid-based coating technology. 3: preparation and characterization of bovine serum albumin particles coated with lipids. J Microencapsul. 2003 Jan-Feb; 20(1):110-28. PMID: 12519706.
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    163. Menei P, Benoit JP. Implantable drug-releasing biodegradable microspheres for local treatment of brain glioma. Acta Neurochir Suppl. 2003; 88:51-5. PMID: 14531561.
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    164. Siepmann J, Faisant N, Benoit JP. A new mathematical model quantifying drug release from bioerodible microparticles using Monte Carlo simulations. Pharm Res. 2002 Dec; 19(12):1885-93. PMID: 12523670.
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    165. Lamprecht A, Bouligand Y, Benoit JP. New lipid nanocapsules exhibit sustained release properties for amiodarone. J Control Release. 2002 Nov 07; 84(1-2):59-68. PMID: 12399168.
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    166. Faisant N, Siepmann J, Oury P, Laffineur V, Bruna E, Haffner J, Benoit J. The effect of gamma-irradiation on drug release from bioerodible microparticles: a quantitative treatment. Int J Pharm. 2002 Aug 21; 242(1-2):281-4. PMID: 12176264.
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    167. Ribeiro Dos Santos I, Richard J, Pech B, Thies C, Benoit JP. Microencapsulation of protein particles within lipids using a novel supercritical fluid process. Int J Pharm. 2002 Aug 21; 242(1-2):69-78. PMID: 12176227.
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    168. Lagarce F, Cruaud O, Deuschel C, Bayssas M, Griffon-Etienne G, Benoit J. Oxaliplatin loaded PLAGA microspheres: design of specific release profiles. Int J Pharm. 2002 Aug 21; 242(1-2):243-6. PMID: 12176255.
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    169. Lamprecht A, Saulnier P, Boury F, Passirani C, Proust JE, Benoit JP. A quantitative method for the determination of amphiphilic drug release kinetics from nanoparticles using a Langmuir balance. Anal Chem. 2002 Jul 15; 74(14):3416-20. PMID: 12139048.
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    170. Gouhier C, Chalon S, Aubert-Pouessel A, Venier-Julienne MC, Jollivet C, Benoit JP, Guilloteau D. Protection of dopaminergic nigrostriatal afferents by GDNF delivered by microspheres in a rodent model of Parkinson's disease. Synapse. 2002 Jun 01; 44(3):124-31. PMID: 11954043.
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    171. Heurtault B, Saulnier P, Pech B, Proust JE, Benoit JP. A novel phase inversion-based process for the preparation of lipid nanocarriers. Pharm Res. 2002 Jun; 19(6):875-80. PMID: 12134960.
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    172. Roullin VG, Deverre JR, Lemaire L, Hindré F, Venier-Julienne MC, Vienet R, Benoit JP. Anti-cancer drug diffusion within living rat brain tissue: an experimental study using [3H](6)-5-fluorouracil-loaded PLGA microspheres. Eur J Pharm Biopharm. 2002 May; 53(3):293-9. PMID: 11976017.
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    173. Faisant N, Siepmann J, Benoit JP. PLGA-based microparticles: elucidation of mechanisms and a new, simple mathematical model quantifying drug release. Eur J Pharm Sci. 2002 May; 15(4):355-66. PMID: 11988397.
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    174. Igartua M, Saulnier P, Heurtault B, Pech B, Proust JE, Pedraz JL, Benoit JP. Development and characterization of solid lipid nanoparticles loaded with magnetite. Int J Pharm. 2002 Feb 21; 233(1-2):149-57. PMID: 11897419.
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    175. Schondorf R, Stein R, Roberts R, Benoit J, Cupples W. Dynamic cerebral autoregulation is preserved in neurally mediated syncope. J Appl Physiol (1985). 2001 Dec; 91(6):2493-502. PMID: 11717210.
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    176. Lemaire L, Roullin VG, Franconi F, Venier-Julienne MC, Menei P, Jallet P, Le Jeune JJ, Benoit JP. Therapeutic efficacy of 5-fluorouracil-loaded microspheres on rat glioma: a magnetic resonance imaging study. NMR Biomed. 2001 Oct; 14(6):360-6. PMID: 11599034.
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    177. Gèze A, Venier-Julienne MC, Cottin J, Faisant N, Benoit JP. PLGA microsphere bioburden evaluation for radiosterilization dose selection. J Microencapsul. 2001 Sep-Oct; 18(5):627-36. PMID: 11508768.
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    178. Veziers J, Lesourd M, Jollivet C, Montero-Menei C, Benoit JP, Menei P. Analysis of brain biocompatibility of drug-releasing biodegradable microspheres by scanning and transmission electron microscopy. J Neurosurg. 2001 Sep; 95(3):489-94. PMID: 11565872.
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    179. Soulié M, Seguin P, Benoit J, Escourrou G, Tollon C, Vazzoler N, Pontonnier F, Plante P. Impact of a modified apical dissection during radical retropubic prostatectomy on the occurrence of positive surgical margins: a comparative study in 212 patients. Urology. 2001 Aug; 58(2):217-21. PMID: 11489704.
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    180. Schondorf R, Benoit J, Stein R. Cerebral autoregulation in orthostatic intolerance. Ann N Y Acad Sci. 2001 Jun; 940:514-26. PMID: 11458706.
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    181. Péan JM, Menei P, Morel O, Montero-Menei CN, Benoit JP. Intraseptal implantation of NGF-releasing microspheres promote the survival of axotomized cholinergic neurons. Biomaterials. 2000 Oct; 21(20):2097-101. PMID: 10966020.
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    182. Benoit J, Routier S, Mérour JY, Colson P, Houssier C, Bailly C. DNA but not topoisomerases is a target for a cytotoxic benzo[5,6]cyclohepta[b]indol-6-one derivative. Anticancer Res. 2000 Sep-Oct; 20(5A):3307-14. PMID: 11062758.
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    183. Gouhier C, Chalon S, Venier-Julienne MC, Bodard S, Benoit J, Besnard J, Guilloteau D. Neuroprotection of nerve growth factor-loaded microspheres on the D2 dopaminergic receptor positive-striatal neurones in quinolinic acid-lesioned rats: a quantitative autoradiographic assessment with iodobenzamide. Neurosci Lett. 2000 Jul 07; 288(1):71-5. PMID: 10869818.
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    184. Benoit JP, Faisant N, Venier-Julienne MC, Menei P. Development of microspheres for neurological disorders: from basics to clinical applications. J Control Release. 2000 Mar 01; 65(1-2):285-96. PMID: 10699288.
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    185. Menei P, Pean JM, Nerrière-Daguin V, Jollivet C, Brachet P, Benoit JP. Intracerebral implantation of NGF-releasing biodegradable microspheres protects striatum against excitotoxic damage. Exp Neurol. 2000 Jan; 161(1):259-72. PMID: 10683292.
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    186. Hardy P, Welby F, Stromboni M, Blin JL, Lortat-Jacob A, Benoit J. Wrist arthroscopy and dislocation of the radiocarpal joint without fracture. Arthroscopy. 1999 Oct; 15(7):779-83. PMID: 10524830.
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    187. Péan JM, Boury F, Venier-Julienne MC, Menei P, Proust JE, Benoit JP. Why does PEG 400 co-encapsulation improve NGF stability and release from PLGA biodegradable microspheres? Pharm Res. 1999 Aug; 16(8):1294-9. PMID: 10468034.
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    188. Menei P, Venier MC, Gamelin E, Saint-André JP, Hayek G, Jadaud E, Fournier D, Mercier P, Guy G, Benoit JP. Local and sustained delivery of 5-fluorouracil from biodegradable microspheres for the radiosensitization of glioblastoma: a pilot study. Cancer. 1999 Jul 15; 86(2):325-30. PMID: 10421269.
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    189. Geze A, Venier-Julienne MC, Saulnier P, Varlet P, Daumas-Duport C, Devauchelle P, Benoit JP. Modulated release of IdUrd from poly (D,L-lactide-co-glycolide) microspheres by addition of poly (D,L-lactide) oligomers. J Control Release. 1999 Apr 19; 58(3):311-22. PMID: 10099156.
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    190. Amiet-Charpentier C, Gadille P, Benoit JP. Rhizobacteria microencapsulation: properties of microparticles obtained by spray-drying. J Microencapsul. 1999 Mar-Apr; 16(2):215-29. PMID: 10080115.
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    191. Schondorf R, Benoit J, Wein T, Phaneuf D. Orthostatic intolerance in the chronic fatigue syndrome. J Auton Nerv Syst. 1999 Feb 15; 75(2-3):192-201. PMID: 10189122.
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    192. Gèze A, Venier-Julienne MC, Mathieu D, Filmon R, Phan-Tan-Luu R, Benoit JP. Development of 5-iodo-2'-deoxyuridine milling process to reduce initial burst release from PLGA microparticles. Int J Pharm. 1999 Feb 15; 178(2):257-68. PMID: 10205645.
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    193. Cruaud O, Benita S, Benoit JP. The characterization and release kinetics evaluation of baclofen microspheres designed for intrathecal injection. Int J Pharm. 1999 Jan 25; 177(2):247-57. PMID: 10205618.
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    194. Geze A, Chourpa I, Boury F, Benoit JP, Dubois P. Direct qualitative and quantitative characterization of a radiosensitizer, 5-iodo-2'-deoxyuridine within biodegradable polymeric microspheres by FT-Raman spectroscopy. Analyst. 1999 Jan; 124(1):37-42. PMID: 10563044.
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    195. Péan JM, Venier-Julienne MC, Boury F, Menei P, Denizot B, Benoit JP. NGF release from poly(D,L-lactide-co-glycolide) microspheres. Effect of some formulation parameters on encapsulated NGF stability. J Control Release. 1998 Dec 04; 56(1-3):175-87. PMID: 9801441.
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    196. Amiet-Charpentier C, Gadille P, Digat B, Benoit JP. Microencapsulation of rhizobacteria by spray-drying: formulation and survival studies. J Microencapsul. 1998 Sep-Oct; 15(5):639-59. PMID: 9743919.
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    197. Rosilio V, Deyme M, Benoit JP, Madelmont G. Physical aging of progesterone-loaded poly(D,L,-lactide-co-glycolide) microspheres. Pharm Res. 1998 May; 15(5):794-8. PMID: 9619792.
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    198. Hardy P, Haab F, Leparc JM, Lortat-Jacob A, Benoit J. Aseptic avascular necrosis of the femoral condyles in renal transplant patients: clinical and radiological aspects on 69 knees. Knee Surg Sports Traumatol Arthrosc. 1998; 6(4):209-14. PMID: 9826801.
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    199. Lachapelle P, Rousseau S, McKerral M, Benoit J, Polomeno RC, Koenekoop RK, Little JM. Evidence supportive of a functional discrimination between photopic oscillatory potentials as revealed with cone and rod mediated retinopathies. Doc Ophthalmol. 1998; 95(1):35-54. PMID: 10189180.
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    200. Benoit J, Meddahi A, Ayoub N, Barritault D, Sezeur A. New healing agent for colonic anastomosis. Int J Colorectal Dis. 1998; 13(2):78-81. PMID: 9638492.
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    201. Painbeni T, Venier-Julienne MC, Benoit JP. Internal morphology of poly(D,L-lactide-co-glycolide) BCNU-loaded microspheres. Influence on drug stability. Eur J Pharm Biopharm. 1998 Jan; 45(1):31-9. PMID: 9689533.
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    202. McKerral M, Roy MS, Benoit J, Leporé F, Lachapelle P. Hemiretinal contribution to the timing of the full-field PVEP as determined with the motor reaction time. Vision Res. 1997 Nov; 37(22):3193-9. PMID: 9463700.
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    203. Schondorf R, Benoit J, Wein T. Cerebrovascular and cardiovascular measurements during neurally mediated syncope induced by head-up tilt. Stroke. 1997 Aug; 28(8):1564-8. PMID: 9259749.
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    204. Pech B, Proust JE, Bouligand Y, Benoit JP. Tensioactivity and supramolecular organization of the palmitoyl prodrug of timolol. Pharm Res. 1997 Jan; 14(1):37-41. PMID: 9034218.
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    205. Boury F, Marchais H, Benoit JP, Proust JE. Surface characterization of poly(alpha-hydroxy acid) microspheres prepared by a solvent evaporation/extraction process. Biomaterials. 1997 Jan; 18(2):125-36. PMID: 9022959.
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    206. Damgé C, Aprahamian M, Marchais H, Benoit JP, Pinget M. Intestinal absorption of PLAGA microspheres in the rat. J Anat. 1996 Dec; 189 ( Pt 3):491-501. PMID: 8982822.
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    207. Meddahi A, Benoit J, Ayoub N, Sézeur A, Barritault D. Heparin-like polymers derived from dextran enhance colonic anastomosis resistance to leakage. J Biomed Mater Res. 1996 Jul; 31(3):293-7. PMID: 8806053.
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    208. Menei P, Boisdron-Celle M, Croué A, Guy G, Benoit JP. Effect of stereotactic implantation of biodegradable 5-fluorouracil-loaded microspheres in healthy and C6 glioma-bearing rats. Neurosurgery. 1996 Jul; 39(1):117-23; discussion 123-4. PMID: 8805147.
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    209. Pérez J, Faure P, Benoit JP. Molecular rigid-body displacements in a tetragonal lysozyme crystal confirmed by X-ray diffuse scattering. Acta Crystallogr D Biol Crystallogr. 1996 Jul 01; 52(Pt 4):722-9. PMID: 15299635.
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    210. Le Parc JM, André T, Helenon O, Benoit J, Paolaggi JB, Kreis H. Osteonecrosis of the hip in renal transplant recipients. Changes in functional status and magnetic resonance imaging findings over three years in three hundred five patients. Rev Rhum Engl Ed. 1996 Jun; 63(6):413-20. PMID: 8817751.
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    211. Lachapelle P, Benoit J, Guité P. The effect of in vivo retinal cooling on the electroretinogram of the rabbit. Vision Res. 1996 Feb; 36(3):339-44. PMID: 8746223.
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    212. Torres AI, Boisdron-Celle M, Benoit JP. Formulation of BCNU-loaded microspheres: influence of drug stability and solubility on the design of the microencapsulation procedure. J Microencapsul. 1996 Jan-Feb; 13(1):41-51. PMID: 8903784.
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    213. Anract P, Katabi M, Forest M, Benoit J, Witvoët J, Tomeno B. [Synovial chondromatosis and chondrosarcoma. A study of the relationship between these two diseases]. Rev Chir Orthop Reparatrice Appar Mot. 1996; 82(3):216-24. PMID: 9005459.
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    214. Benoit J, Cruaud P, Lauroy J, Boutelier P, Champault G. [Does laparoscopic treatment of abdominal infections generate bacteremias? Prospective study: 75 cases]. J Chir (Paris). 1995 Dec; 132(12):472-7. PMID: 8815057.
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    215. Benoit JL, Carandang G, Sitrin M, Arnow PM. Intraluminal antibiotic treatment of central venous catheter infections in patients receiving parenteral nutrition at home. Clin Infect Dis. 1995 Nov; 21(5):1286-8. PMID: 8589156.
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    216. Benoit JP, Doucet J. Diffuse scattering in protein crystallography. Q Rev Biophys. 1995 May; 28(2):131-69. PMID: 7568674.
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    217. Boisdron-Celle M, Menei P, Benoit JP. Preparation and characterization of 5-fluorouracil-loaded microparticles as biodegradable anticancer drug carriers. J Pharm Pharmacol. 1995 Feb; 47(2):108-14. PMID: 7602463.
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    218. Venier-Julienne MC, Vouldoukis I, Monjour L, Benoit JP. In vitro study of the anti-leishmanial activity of biodegradable nanoparticles. J Drug Target. 1995; 3(1):23-9. PMID: 7655817.
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    219. Menei P, Croué A, Daniel V, Pouplard-Barthelaix A, Benoit JP. Fate and biocompatibility of three types of microspheres implanted into the brain. J Biomed Mater Res. 1994 Sep; 28(9):1079-85. PMID: 7814435.
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    220. Menei P, Benoit JP, Boisdron-Celle M, Fournier D, Mercier P, Guy G. Drug targeting into the central nervous system by stereotactic implantation of biodegradable microspheres. Neurosurgery. 1994 Jun; 34(6):1058-64; discussion 1064. PMID: 8084391.
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    221. Hardy P, Benoit J, Donneaud B, Jehanno P, Lortat-Jacob A. [Pathological fractures of the femoral neck in hemodialyzed patients. Apropos of 26 cases]. Rev Chir Orthop Reparatrice Appar Mot. 1994; 80(8):702-10. PMID: 7638399.
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    222. Guillet V, Lapthorn A, Fourniat J, Benoit JP, Hartley RW, Mauguen Y. Crystallization and preliminary X-ray investigation of barstar, the intracellular inhibitor of barnase. Proteins. 1993 Nov; 17(3):325-8. PMID: 8272429.
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    223. Menei P, Daniel V, Montero-Menei C, Brouillard M, Pouplard-Barthelaix A, Benoit JP. Biodegradation and brain tissue reaction to poly(D,L-lactide-co-glycolide) microspheres. Biomaterials. 1993 May; 14(6):470-8. PMID: 8507795.
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    224. Pech B, Chetoni P, Saettone MF, Duval O, Benoit JP. Preliminary evaluation of a series of amphiphilic timolol prodrugs: possible evidence for transscleral absorption. J Ocul Pharmacol. 1993; 9(2):141-50. PMID: 8345286.
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    225. Lachapelle P, Benoit J, Little JM, Lachapelle B. Recording the oscillatory potentials of the electroretinogram with the DTL electrode. Doc Ophthalmol. 1993; 83(2):119-30. PMID: 8334927.
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    226. Deverre JR, Loiseau P, Puisieux F, Gayral P, Letourneux Y, Couvreur P, Benoit JP. Synthesis of the orally macrofilaricidal and stable glycerolipidic prodrug of melphalan, 1,3-dipalmitoyl-2-(4'(bis(2''-chloroethyl)amino)phenylalaninoyl)gl ycerol. Arzneimittelforschung. 1992 Sep; 42(9):1153-6. PMID: 1445485.
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    227. Lortat-Jacob A, Videcoq P, Hardy P, Fontes D, de Somer B, Benoit J. [Bipolar endoprosthesis in fractures of the femoral neck. Apropos of 201 cases, 116 after a 6-year follow-up]. Rev Chir Orthop Reparatrice Appar Mot. 1992; 78(3):191-200. PMID: 1439032.
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    228. McKerral M, Lachapelle P, Benoit J. Comparative effects of luminance and scatter on the pattern visual evoked potential and eye-hand reaction time. Doc Ophthalmol. 1992; 79(2):177-85. PMID: 1591971.
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    229. Deverre JR, Loiseau P, Gayral P, Letourneux Y, Couvreur P, Benoit JP. In vitro and in vivo evaluation of macrofilaricidal activity of GABA and 1,3-dipalmitoyl-2-(4-aminobutyryl)glycerol HCl: a diglyceride prodrug. Pharm Acta Helv. 1992; 67(12):349-52. PMID: 1488452.
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    230. Fontes D, Lenoble E, de Somer B, Benoit J. [Lesions of the ligaments associated with distal fractures of the radius. 58 intraoperative arthrographies]. Ann Chir Main Memb Super. 1992; 11(2):119-25. PMID: 1380266.
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    231. Dubernet C, Rouland JC, Benoit JP. Ibuprofen-loaded ethylcellulose microspheres: analysis of the matrix structure by thermal analysis. J Pharm Sci. 1991 Nov; 80(11):1029-33. PMID: 1815052.
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    232. Gallot D, Malafosse M, Contou JF, Maurel J, Benoit J. [Local surgical treatment of anal-perineal lesions in Crohn's disease. Retrospective study of 68 cases]. Ann Gastroenterol Hepatol (Paris). 1991 Nov; 27(6):243-8. PMID: 1772234.
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    233. Rosilio V, Benoit JP, Deyme M, Thies C, Madelmont G. A physicochemical study of the morphology of progesterone-loaded microspheres fabricated from poly(D,L-lactide-co-glycolide). J Biomed Mater Res. 1991 May; 25(5):667-82. PMID: 1869581.
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    234. Wright J, Duchesne C, Sabourin S, Bissonnette F, Benoit J, Girard Y. Psychosocial distress and infertility: men and women respond differently. Fertil Steril. 1991 Jan; 55(1):100-8. PMID: 1986949.
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    235. Dubernet C, Benoit JP, Peppas NA, Puisieux F. Ibuprofen-loaded ethylcellulose microspheres: release studies and analysis of the matrix structure through the Higuchi model. J Microencapsul. 1990 Oct-Dec; 7(4):555-65. PMID: 2266479.
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    236. Lachapelle P, Benoit J, Guité P, Tran CN, Molotchnikoff S. The effect of iodoacetic acid on the electroretinogram and oscillatory potentials in rabbits. Doc Ophthalmol. 1990 Aug; 75(1):7-14. PMID: 2265579.
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    237. Guise V, Drouin JY, Benoit J, Mahuteau J, Dumont P, Couvreur P. Vidarabine-loaded nanoparticles: a physicochemical study. Pharm Res. 1990 Jul; 7(7):736-41. PMID: 2395802.
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    238. Lortat-Jacob A, Hardy P, Benoit J. [Early reoperation for infection in orthopedic surgery of the leg (arthroplasties and hip surgical procedures excluded)]. Rev Chir Orthop Reparatrice Appar Mot. 1990; 76(5):321-8. PMID: 2148414.
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    239. Hernigou P, Thiéry JP, Benoit J, Voisin MC, Leroux P, Hagege G, Delepine G, Goutallier D. Methotrexate diffusion from acrylic cement. Local chemotherapy for bone tumours. J Bone Joint Surg Br. 1989 Nov; 71(5):804-11. PMID: 2584251.
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    240. Spenlehauer G, Vert M, Benoit JP, Boddaert A. In vitro and in vivo degradation of poly(D,L lactide/glycolide) type microspheres made by solvent evaporation method. Biomaterials. 1989 Oct; 10(8):557-63. PMID: 2605288.
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    241. Deverre JR, Loiseau P, Couvreur P, Letourneux Y, Gayral P, Benoit JP. In-vitro evaluation of filaricidal activity of GABA and 1,3-dipalmitoyl-2-(4-aminobutyryl)glycerol HCl: a diglyceride prodrug. J Pharm Pharmacol. 1989 Mar; 41(3):191-3. PMID: 2568448.
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    242. Chiannilkulchai N, Driouich Z, Benoit JP, Parodi AL, Couvreur P. [Nanoparticles of doxorubicin: colloidal vectors in the treatment of hepatic metastases in animals]. Bull Cancer. 1989; 76(8):845-8. PMID: 2620111.
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    243. Chiannilkulchai N, Driouich Z, Benoit JP, Parodi AL, Couvreur P. Doxorubicin-loaded nanoparticles: increased efficiency in murine hepatic metastases. Sel Cancer Ther. 1989; 5(1):1-11. PMID: 2756244.
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    244. Sawaya A, Fickat R, Benoit JP, Puisieux F, Benita S. Ion-exchange albumin microcapsules of doxorubicin: an in vitro release kinetic evaluation. J Microencapsul. 1988 Jul-Sep; 5(3):255-67. PMID: 3199310.
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    245. Benoit J, Cormier M, Wepierre J. Comparative effects of four surfactants on growth, contraction and adhesion of cultured human fibroblasts. Cell Biol Toxicol. 1988 Mar; 4(1):111-22. PMID: 3228705.
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    246. Couvreur P, Fattal E, Andremont A, Chiannilkulchai N, Benoit JP. [The use of nano-particles for the vectorization of antibiotic and antineoplastic drugs]. Bull Mem Acad R Med Belg. 1988; 143(7-9):378-88. PMID: 3252954.
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    247. Saslawski O, Weingarten C, Benoit JP, Couvreur P. Magnetically responsive microspheres for the pulsed delivery of insulin. Life Sci. 1988; 42(16):1521-8. PMID: 3280940.
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    248. Frank A, Beaufils P, Rua R, Benoit J. [Arthroscopy in post-traumatic hemarthrosis of the knee. Apropos of 173 cases]. Rev Chir Orthop Reparatrice Appar Mot. 1988; 74 Suppl 2:177-80. PMID: 3231770.
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    249. Gaston A, Marsault C, Lacaze A, Gianese P, Nguyen JP, Keravel Y, Benabid AL, Aussage P, Benoit JP. External magnetic guidance of endovascular catheters with a superconducting magnet: preliminary trials. Experimental studies in dogs and prospects of application. J Neuroradiol. 1988; 15(2):137-47. PMID: 3216230.
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    250. Sawaya A, Benoit JP, Benita S. Binding mechanism of doxorubicin in ion-exchange albumin microcapsules. J Pharm Sci. 1987 Jun; 76(6):475-80. PMID: 3625494.
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    251. Sawaya A, Deyme M, Benoit JP. Calcium and thiocyanate interactions with crosslinked albumin microcapsules: influence of the reticulation rate. Biomaterials. 1987 May; 8(3):211-6. PMID: 3607154.
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    252. Hernigou P, Thiery JP, Benoit JP, Voisin MC, Leroux P, Hagege G, Délépine G, Goutallier D. [Experimental study on osteosarcoma of local chemotherapy diffusing from surgical acrylic cement and plaster]. Rev Chir Orthop Reparatrice Appar Mot. 1987; 73(7):517-29. PMID: 3481447.
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    253. Benoit J, Cormier M, Wepierre J. Effect of proteins on the assessment of surfactant cytotoxicity by an in vitro test: Possible correlations with in vivo data. Toxicol In Vitro. 1987; 1(2):91-6. PMID: 20647072.
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    254. Benoit JP, Couvreur P, Devissaguet JP, Fessi H, Puisieux F, Roblot-Treupel L. ["Carrier" or "modulated distribution" forms, new systems for drug administration]. J Pharm Belg. 1986 Sep-Oct; 41(5):319-29. PMID: 3543289.
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    255. Benita S, Zouai O, Benoit JP. 5-Fluorouracil:carnauba wax microspheres for chemoembolization: an in vitro evaluation. J Pharm Sci. 1986 Sep; 75(9):847-51. PMID: 3783451.
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    256. Cavalier M, Benoit JP, Thies C. The formation and characterization of hydrocortisone-loaded poly((+/-)-lactide) microspheres. J Pharm Pharmacol. 1986 Apr; 38(4):249-53. PMID: 2872287.
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    257. Duc-Mauger A, Benoit JP, Puisieux F. Preparation and characterization of cross-linked human serum albumin microcapsules containing 5-fluorouracil. Pharm Acta Helv. 1986; 61(4):119-24. PMID: 3725808.
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    258. Benita S, Benoit JP, Puisieux F, Thies C. Characterization of drug-loaded poly(d,l-lactide) microspheres. J Pharm Sci. 1984 Dec; 73(12):1721-4. PMID: 6527243.
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