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Connection

Lucy Godley to 5-Methylcytosine

This is a "connection" page, showing publications Lucy Godley has written about 5-Methylcytosine.
Connection Strength

2.775
  1. MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia. Epigenetics. 2022 12; 17(13):2056-2074.
    View in: PubMed
    Score: 0.784
  2. 5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy. Cancer Genet. 2015 May; 208(5):167-77.
    View in: PubMed
    Score: 0.469
  3. New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine. Immunol Rev. 2015 Jan; 263(1):36-49.
    View in: PubMed
    Score: 0.463
  4. 5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma. Clin Cancer Res. 2020 03 15; 26(6):1309-1317.
    View in: PubMed
    Score: 0.163
  5. Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways. Genome Res. 2017 11; 27(11):1830-1842.
    View in: PubMed
    Score: 0.140
  6. TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer. Sci Rep. 2015 Dec 03; 5:17568.
    View in: PubMed
    Score: 0.123
  7. TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma. Cell Rep. 2014 Jun 12; 7(5):1343-1352.
    View in: PubMed
    Score: 0.111
  8. Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis. Cell Rep. 2014 Jan 16; 6(1):231-244.
    View in: PubMed
    Score: 0.108
  9. Perturbations of 5-hydroxymethylcytosine patterning in hematologic malignancies. Semin Hematol. 2013 Jan; 50(1):61-9.
    View in: PubMed
    Score: 0.101
  10. Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors. Blood. 2011 Sep 01; 118(9):2551-5.
    View in: PubMed
    Score: 0.091
  11. DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia. Cell Rep. 2014 Dec 11; 9(5):1841-1855.
    View in: PubMed
    Score: 0.029
  12. Large conserved domains of low DNA methylation maintained by Dnmt3a. Nat Genet. 2014 Jan; 46(1):17-23.
    View in: PubMed
    Score: 0.027
  13. Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer. Nucleic Acids Res. 2013 Sep; 41(16):e157.
    View in: PubMed
    Score: 0.026
  14. Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis. Nat Genet. 2012 Nov; 44(11):1179-81.
    View in: PubMed
    Score: 0.025
  15. 2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine levels. Leuk Lymphoma. 2013 Feb; 54(2):408-10.
    View in: PubMed
    Score: 0.024
  16. Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia. Epigenetics. 2012 Feb; 7(2):201-7.
    View in: PubMed
    Score: 0.024
  17. 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat Neurosci. 2011 Oct 30; 14(12):1607-16.
    View in: PubMed
    Score: 0.023
  18. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol. 2011 Jan; 29(1):68-72.
    View in: PubMed
    Score: 0.022
  19. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell. 2010 Dec 14; 18(6):553-67.
    View in: PubMed
    Score: 0.022
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.