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Louis Portugal

InstitutionUniversity of Chicago
DepartmentSurgery-Otolaryngology-Head and Neck
AddressChicago IL 60637
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    Collapse Overview 
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    Louis de Guzman Portugal, MD, specializes in the latest diagnostic, treatment and surgical techniques for head and neck disorders, including allergy and sinus disorders — as well as head, neck and esophageal cancers. Dr. Portugal is a member of the Center for Esophageal Diseases, where he works with a multidisciplinary team to treat all stages of esophageal cancer.

    Dr. Portugal is studying new methods of detection and treatment for patients with head and neck cancer.

    Collapse Biography 
    Collapse education and training
    University of CincinnatiFellowship
    University of Illinois College of MedicineResidency
    University of Illinois College of MedicineInternship
    University of Missouri School of MedicineMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yesensky J, Agrawal N, Bayan S, Blair E, Portugal L, Chan J, Goldenberg D, Gooi Z. AHNS Series - Do you know your guidelines? Principles of treatment for glottic cancer: A review of the National Comprehensive Cancer Network guidelines. Head Neck. 2017 09; 39(9):1729-1732. PMID: 28653453.
      Citations: 2     Fields:    Translation:Humans
    2. Ginat DT, Schulte J, Portugal L, Cipriani NA. Laryngotracheal Involvement in Systemic Light Chain Amyloidosis. Head Neck Pathol. 2018 Mar; 12(1):127-130. PMID: 28616786; PMCID: PMC5873486.
      Citations: 3     Fields:    Translation:Humans
    3. Gooi Z, Richmon J, Agrawal N, Blair E, Portugal L, Vokes E, Seiwert T, de Souza J, Saloura V, Haraf D, Goldenberg D, Chan J. AHNS Series - Do you know your guidelines? Principles of treatment for nasopharyngeal cancer: A review of the National Comprehensive Cancer Network guidelines. Head Neck. 2017 02; 39(2):201-205. PMID: 27898198.
      Citations: 5     Fields:    Translation:Humans
    4. Ginat DT, Portugal L. Lingual osseous choristoma. Ear Nose Throat J. 2016 Jul; 95(7):260-1. PMID: 27434471.
      Citations: 3     Fields:    Translation:Humans
    5. Villaflor VM, Melotek JM, Karrison TG, Brisson RJ, Blair EA, Portugal L, De Souza JA, Ginat DT, Stenson KM, Langerman A, Kocherginsky M, Spiotto MT, Hannigan N, Seiwert TY, Cohen EE, Vokes EE, Haraf DJ. Response-adapted volume de-escalation (RAVD) in locally advanced head and neck cancer. Ann Oncol. 2016 05; 27(5):908-13. PMID: 26884588.
      Citations: 33     Fields:    Translation:HumansCTClinical Trials
    6. Seiwert TY, Zuo Z, Keck MK, Khattri A, Pedamallu CS, Stricker T, Brown C, Pugh TJ, Stojanov P, Cho J, Lawrence MS, Getz G, DeBoer R, Weichselbaum RR, Langerman A, Portugal L, Blair E, Stenson K, Lingen MW, Cohen EE, Vokes EE, White KP, Hammerman PS, Brägelmann J. Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas. Clin Cancer Res. 2015 Feb 01; 21(3):632-41. PMID: 25056374; PMCID: PMC4305034.
      Citations: 314     Fields:    Translation:HumansCells
    7. Stenson KM, Maccracken E, Kunnavakkam R, W Cohen EE, Portugal LD, Villaflor V, Seiwert T, Blair E, Haraf DJ, Salama JK, Vokes EE. Chemoradiation for patients with large-volume laryngeal cancers. Head Neck. 2012 Aug; 34(8):1162-7. PMID: 22052816.
      Citations: 4     Fields:    Translation:Humans
    8. Pederson AW, Salama JK, Haraf DJ, Witt ME, Stenson KM, Portugal L, Seiwert T, Villaflor VM, Cohen EE, Vokes EE, Blair EA. Adjuvant chemoradiotherapy for locoregionally advanced and high-risk salivary gland malignancies. Head Neck Oncol. 2011 Jul 26; 3:31. PMID: 21791072; PMCID: PMC3189162.
      Citations: 14     Fields:    Translation:Humans
    9. Cipriani NA, Martin DE, Corey JP, Portugal L, Caballero N, Lester R, Anthony B, Taxy JB. The clinicopathologic spectrum of benign mass lesions of the vocal fold due to vocal abuse. Int J Surg Pathol. 2011 Oct; 19(5):583-7. PMID: 21685134.
      Citations: 13     Fields:    Translation:Humans
    10. Choe KS, Haraf DJ, Solanki A, Cohen EE, Seiwert TY, Stenson KM, Blair EA, Portugal L, Villaflor VM, Witt ME, Vokes EE, Salama JK. Prior chemoradiotherapy adversely impacts outcomes of recurrent and second primary head and neck cancer treated with concurrent chemotherapy and reirradiation. Cancer. 2011 Oct 15; 117(20):4671-8. PMID: 21671479.
      Citations: 21     Fields:    Translation:Humans
    11. Villaflor VM, Haraf D, Salama JK, Kocherginsky M, Langerman A, Gomez-Abuin G, Beniwal P, Blair EA, Stenson KM, Portugal L, Seiwert T, Williams RD, Dekker AJ, Witt ME, Vokes EE, Cohen EEW. Phase II trial of pemetrexed-based induction chemotherapy followed by concomitant chemoradiotherapy in previously irradiated patients with squamous cell carcinoma of the head and neck. Ann Oncol. 2011 Nov; 22(11):2501-2507. PMID: 21385883.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    12. Stenson KM, Kunnavakkam R, Cohen EE, Portugal LD, Blair E, Haraf DJ, Salama J, Vokes EE. Chemoradiation for patients with advanced oral cavity cancer. Laryngoscope. 2010 Jan; 120(1):93-9. PMID: 19856305.
      Citations: 29     Fields:    Translation:Humans
    13. Villaflor VM, Cohen EE, Haraf D, Stenson K, Blair E, Salama J, Portugal L, Williams R, Thomas A, Gomez-Abuin G, Vokes EE. Phase II trial pemetrexed-based induction chemotherapy followed by concomitant chemoradiotherapy in previously irradiated head and neck cancer patients. J Clin Oncol. 2008 May 20; 26(15_suppl):6030. PMID: 27950566.
    14. Brockstein B, Haraf DJ, Rademaker AW, Kies MS, Stenson KM, Rosen F, Mittal BB, Pelzer H, Fung BB, Witt ME, Wenig B, Portugal L, Weichselbaum RW, Vokes EE. Patterns of failure, prognostic factors and survival in locoregionally advanced head and neck cancer treated with concomitant chemoradiotherapy: a 9-year, 337-patient, multi-institutional experience. Ann Oncol. 2004 Aug; 15(8):1179-86. PMID: 15277256.
      Citations: 115     Fields:    Translation:Humans
    15. Argiris A, Stenson KM, Brockstein BE, Mittal BB, Pelzer H, Kies MS, Jayaram P, Portugal L, Wenig BL, Rosen FR, Haraf DJ, Vokes EE. Neck dissection in the combined-modality therapy of patients with locoregionally advanced head and neck cancer. Head Neck. 2004 May; 26(5):447-55. PMID: 15122662.
      Citations: 29     Fields:    Translation:Humans
    16. Haraf DJ, Rosen FR, Stenson K, Argiris A, Mittal BB, Witt ME, Brockstein BE, List MA, Portugal L, Pelzer H, Weichselbaum RR, Vokes EE. Induction chemotherapy followed by concomitant TFHX chemoradiotherapy with reduced dose radiation in advanced head and neck cancer. Clin Cancer Res. 2003 Dec 01; 9(16 Pt 1):5936-43. PMID: 14676118.
      Citations: 13     Fields:    Translation:Humans
    17. Rosen FR, Haraf DJ, Kies MS, Stenson K, Portugal L, List MA, Brockstein BE, Mittal BB, Rademaker AW, Witt ME, Pelzer H, Weichselbaum RR, Vokes EE. Multicenter randomized Phase II study of paclitaxel (1-hour infusion), fluorouracil, hydroxyurea, and concomitant twice daily radiation with or without erythropoietin for advanced head and neck cancer. Clin Cancer Res. 2003 May; 9(5):1689-97. PMID: 12738722.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    18. Vokes EE, Stenson K, Rosen FR, Kies MS, Rademaker AW, Witt ME, Brockstein BE, List MA, Fung BB, Portugal L, Mittal BB, Pelzer H, Weichselbaum RR, Haraf DJ. Weekly carboplatin and paclitaxel followed by concomitant paclitaxel, fluorouracil, and hydroxyurea chemoradiotherapy: curative and organ-preserving therapy for advanced head and neck cancer. J Clin Oncol. 2003 Jan 15; 21(2):320-6. PMID: 12525525.
      Citations: 41     Fields:    Translation:Humans
    19. Cundiff JG, Portugal L, Sarne DH. Parathyroid adenoma after radioactive iodine therapy for multinodular goiter. Am J Otolaryngol. 2001 Sep-Oct; 22(5):374-5. PMID: 11562893.
      Citations:    Fields:    Translation:Humans
    20. Kies MS, Haraf DJ, Rosen F, Stenson K, List M, Brockstein B, Chung T, Mittal BB, Pelzer H, Portugal L, Rademaker A, Weichselbaum R, Vokes EE. Concomitant infusional paclitaxel and fluorouracil, oral hydroxyurea, and hyperfractionated radiation for locally advanced squamous head and neck cancer. J Clin Oncol. 2001 Apr 01; 19(7):1961-9. PMID: 11283128.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    21. Schwartz GJ, Mehta RH, Wenig BL, Shaligram C, Portugal LG. Salvage treatment for recurrent squamous cell carcinoma of the oral cavity. Head Neck. 2000 Jan; 22(1):34-41. PMID: 10585603.
      Citations: 36     Fields:    Translation:Humans
    22. Desai DP, Portugal LG, Walner DL, Mafee MF, Schild JA. Bilateral saccular cysts after cocaine use. Otolaryngol Head Neck Surg. 1999 May; 120(5):754-7. PMID: 10229608.
      Citations: 1     Fields:    Translation:Humans
    23. Dayan SH, Portugal LG, Walner DL, Berkowitz R. Laryngeal obstruction after inhalation of a penny from a metered-dose inhaler. Otolaryngol Head Neck Surg. 1999 Apr; 120(4):548-51. PMID: 10187955.
      Citations: 1     Fields:    Translation:Humans
    24. Goldenberg JD, Portugal LG, Wenig BL, Ferrer K, Wu JC, Sabnani J. Well-differentiated thyroid carcinomas: p53 mutation status and microvessel density. Head Neck. 1998 Mar; 20(2):152-8. PMID: 9484947.
      Citations: 6     Fields:    Translation:Humans
    25. Portugal LG, Goldenberg JD, Wenig BL, Ferrer KT, Nodzenski E, Sabnani JB, Javier C, Weichselbaum RR, Vokes EE. Human papillomavirus expression and p53 gene mutations in squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 1997 Nov; 123(11):1230-4. PMID: 9366703.
      Citations: 10     Fields:    Translation:HumansCells
    26. Gluckman JL, Pavelic ZP, Welkoborsky HJ, Mann W, Stambrook P, Gleich L, Wilson K, Righi P, Portugal LG, McDonald J, Biddinger P, Steward D, Gartside P. Prognostic indicators for squamous cell carcinoma of the oral cavity: a clinicopathologic correlation. Laryngoscope. 1997 Sep; 107(9):1239-44. PMID: 9292610.
      Citations: 8     Fields:    Translation:HumansCells
    27. Portugal LG, Mehta RH, Smith BE, Sabnani JB, Matava MJ. Objective assessment of the breathe-right device during exercise in adult males. Am J Rhinol. 1997 Sep-Oct; 11(5):393-7. PMID: 9768322.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    28. Goldenberg JD, Portugal LG, Wenig BL, Weingarten RT. Negative-pressure pulmonary edema in the otolaryngology patient. Otolaryngol Head Neck Surg. 1997 Jul; 117(1):62-6. PMID: 9230325.
      Citations: 14     Fields:    Translation:Humans
    29. Geraghty JA, Wenig BL, Smith BE, Portugal LG. Long-term follow-up of tracheoesophageal puncture results. Ann Otol Rhinol Laryngol. 1996 Jul; 105(7):501-3. PMID: 8678423.
      Citations: 1     Fields:    Translation:Humans
    30. Portugal LG, Wilson KM, Biddinger PW, Gluckman JL. The role of toluidine blue in assessing margin status after resection of squamous cell carcinomas of the upper aerodigestive tract. Arch Otolaryngol Head Neck Surg. 1996 May; 122(5):517-9. PMID: 8615969.
      Citations: 9     Fields:    Translation:Humans
    31. Gluckman JL, Portugal LG. Photodynamic therapy for cancer of the head and neck. Cancer Treat Res. 1995; 74:159-71. PMID: 7779614.
      Citations: 2     Fields:    Translation:Humans
    32. Gluckman JL, Portugal LG. Modified Young's procedure for refractory epistaxis due to hereditary hemorrhagic telangiectasia. Laryngoscope. 1994 Sep; 104(9):1174-7. PMID: 8072369.
      Citations: 10     Fields:    Translation:Humans
    33. Pavelic ZP, Portugal LG, Gootee MJ, Stambrook PJ, Smith C, Mugge RE, Pavelic L, Wilson K, Buncher CR, Li YQ, et al. Retrieval of p53 protein in paraffin-embedded head and neck tumor tissues. Arch Otolaryngol Head Neck Surg. 1993 Nov; 119(11):1206-9. PMID: 7692889.
      Citations: 6     Fields:    Translation:Humans
    34. Portugal LG, Gluckman JL, Biddinger PW. Sclerosing cervicitis: an unusual cause of syncope. Am J Otolaryngol. 1993 Sep-Oct; 14(5):358-62. PMID: 8238766.
      Citations:    Fields:    Translation:Humans
    35. Gluckman JL, Portugal LG. Photodynamic therapy for cutaneous malignancies of the head and neck. Otolaryngol Clin North Am. 1993 Apr; 26(2):311-8. PMID: 8460045.
      Citations:    Fields:    Translation:Humans
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