Jonathan Pritchard to Humans
This is a "connection" page, showing publications Jonathan Pritchard has written about Humans.
Connection Strength
1.205
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Gene regulatory network inference from CRISPR perturbations in primary CD4+ T cells elucidates the genomic basis of immune disease. Cell Genom. 2024 Nov 13; 4(11):100671.
Score: 0.032
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Bayesian estimation of gene constraint from an evolutionary model with gene features. Nat Genet. 2024 Aug; 56(8):1632-1643.
Score: 0.031
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Stable population structure in Europe since the Iron Age, despite high mobility. Elife. 2024 Jan 30; 13.
Score: 0.030
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Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits. Am J Hum Genet. 2022 07 07; 109(7):1286-1297.
Score: 0.027
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GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background. Elife. 2021 02 15; 10.
Score: 0.025
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Trans Effects on Gene Expression Can Drive Omnigenic Inheritance. Cell. 2019 05 02; 177(4):1022-1034.e6.
Score: 0.022
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Evidence for Weak Selective Constraint on Human Gene Expression. Genetics. 2019 02; 211(2):757-772.
Score: 0.021
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Post-translational buffering leads to convergent protein expression levels between primates. Genome Biol. 2018 06 27; 19(1):83.
Score: 0.021
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Frequent nonallelic gene conversion on the human lineage and its effect on the divergence of gene duplicates. Proc Natl Acad Sci U S A. 2017 11 28; 114(48):12779-12784.
Score: 0.020
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Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression. Am J Hum Genet. 2017 Nov 02; 101(5):686-699.
Score: 0.020
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An Expanded View of Complex Traits: From Polygenic to Omnigenic. Cell. 2017 Jun 15; 169(7):1177-1186.
Score: 0.019
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Rapid evolution of the human mutation spectrum. Elife. 2017 04 25; 6.
Score: 0.019
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Mutation Rate Variation is a Primary Determinant of the Distribution of Allele Frequencies in Humans. PLoS Genet. 2016 Dec; 12(12):e1006489.
Score: 0.019
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Detection of human adaptation during the past 2000 years. Science. 2016 11 11; 354(6313):760-764.
Score: 0.018
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Genetic variation in MHC proteins is associated with T cell receptor expression biases. Nat Genet. 2016 09; 48(9):995-1002.
Score: 0.018
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Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling. Elife. 2016 05 27; 5.
Score: 0.018
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Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals. Science. 2016 May 20; 352(6288):1009-13.
Score: 0.018
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RNA splicing is a primary link between genetic variation and disease. Science. 2016 Apr 29; 352(6285):600-4.
Score: 0.018
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WASP: allele-specific software for robust molecular quantitative trait locus discovery. Nat Methods. 2015 Nov; 12(11):1061-3.
Score: 0.017
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The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines. PLoS One. 2014; 9(9):e107166.
Score: 0.016
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fastSTRUCTURE: variational inference of population structure in large SNP data sets. Genetics. 2014 Jun; 197(2):573-89.
Score: 0.015
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Archaic humans: Four makes a party. Nature. 2014 Jan 02; 505(7481):32-4.
Score: 0.015
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Identification of genetic variants that affect histone modifications in human cells. Science. 2013 Nov 08; 342(6159):747-9.
Score: 0.015
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Inference of population splits and mixtures from genome-wide allele frequency data. PLoS Genet. 2012; 8(11):e1002967.
Score: 0.014
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Controls of nucleosome positioning in the human genome. PLoS Genet. 2012; 8(11):e1003036.
Score: 0.014
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Comment on "Widespread RNA and DNA sequence differences in the human transcriptome". Science. 2012 Mar 16; 335(6074):1302; author reply 1302.
Score: 0.013
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Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data. PLoS One. 2012; 7(2):e30629.
Score: 0.013
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DNase?I sensitivity QTLs are a major determinant of human expression variation. Nature. 2012 Feb 05; 482(7385):390-4.
Score: 0.013
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Dissecting the regulatory architecture of gene expression QTLs. Genome Biol. 2012 Jan 31; 13(1):R7.
Score: 0.013
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Whole-genome sequencing data offer insights into human demography. Nat Genet. 2011 Sep 28; 43(10):923-5.
Score: 0.013
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Efficient counting of k-mers in DNA sequences using a bloom filter. BMC Bioinformatics. 2011 Aug 10; 12:333.
Score: 0.013
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False positive peaks in ChIP-seq and other sequencing-based functional assays caused by unannotated high copy number regions. Bioinformatics. 2011 Aug 01; 27(15):2144-6.
Score: 0.013
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DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol. 2011; 12(1):R10.
Score: 0.012
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Noisy splicing drives mRNA isoform diversity in human cells. PLoS Genet. 2010 Dec 09; 6(12):e1001236.
Score: 0.012
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Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data. Genome Res. 2011 Mar; 21(3):447-55.
Score: 0.012
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How we are evolving. Sci Am. 2010 Oct; 303(4):40-7.
Score: 0.012
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Adaptation - not by sweeps alone. Nat Rev Genet. 2010 Oct; 11(10):665-7.
Score: 0.012
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Using environmental correlations to identify loci underlying local adaptation. Genetics. 2010 Aug; 185(4):1411-23.
Score: 0.012
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Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature. 2010 Apr 01; 464(7289):768-72.
Score: 0.012
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The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation. Curr Biol. 2010 Feb 23; 20(4):R208-15.
Score: 0.012
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Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data. Bioinformatics. 2009 Dec 15; 25(24):3207-12.
Score: 0.011
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The role of geography in human adaptation. PLoS Genet. 2009 Jun; 5(6):e1000500.
Score: 0.011
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Signals of recent positive selection in a worldwide sample of human populations. Genome Res. 2009 May; 19(5):826-37.
Score: 0.011
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Gene expression levels are a target of recent natural selection in the human genome. Mol Biol Evol. 2009 Mar; 26(3):649-58.
Score: 0.011
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High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet. 2008 Oct; 4(10):e1000214.
Score: 0.011
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Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet. 2008 Aug; 24(8):408-15.
Score: 0.010
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Adaptive evolution of conserved noncoding elements in mammals. PLoS Genet. 2007 Sep; 3(9):1572-86.
Score: 0.010
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Overcoming the winner's curse: estimating penetrance parameters from case-control data. Am J Hum Genet. 2007 Apr; 80(4):605-15.
Score: 0.009
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A worldwide survey of haplotype variation and linkage disequilibrium in the human genome. Nat Genet. 2006 Nov; 38(11):1251-60.
Score: 0.009
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A map of recent positive selection in the human genome. PLoS Biol. 2006 Mar; 4(3):e72.
Score: 0.009
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A high-resolution survey of deletion polymorphism in the human genome. Nat Genet. 2006 Jan; 38(1):75-81.
Score: 0.009
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Confounding from cryptic relatedness in case-control association studies. PLoS Genet. 2005 Sep; 1(3):e32.
Score: 0.008
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Coalescent-based association mapping and fine mapping of complex trait loci. Genetics. 2005 Feb; 169(2):1071-92.
Score: 0.008
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Statistical tests for admixture mapping with case-control and cases-only data. Am J Hum Genet. 2004 Nov; 75(5):771-89.
Score: 0.008
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Invasive Treatment Strategy for Older Patients with Myocardial Infarction. N Engl J Med. 2024 Nov 07; 391(18):1673-1684.
Score: 0.008
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Diversity of ribosomes at the level of rRNA variation associated with human health and disease. Cell Genom. 2024 Sep 11; 4(9):100629.
Score: 0.008
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Base-editing mutagenesis maps alleles to tune human T cell functions. Nature. 2024 Jan; 625(7996):805-812.
Score: 0.008
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Informativeness of genetic markers for inference of ancestry. Am J Hum Genet. 2003 Dec; 73(6):1402-22.
Score: 0.008
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CRISPR screens decode cancer cell pathways that trigger ?d T cell detection. Nature. 2023 Sep; 621(7977):188-195.
Score: 0.007
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A genetic history of continuity and mobility in the Iron Age central Mediterranean. Nat Ecol Evol. 2023 09; 7(9):1515-1524.
Score: 0.007
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A genome-wide genetic screen uncovers determinants of human pigmentation. Science. 2023 08 11; 381(6658):eade6289.
Score: 0.007
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Haplotype blocks and linkage disequilibrium in the human genome. Nat Rev Genet. 2003 Aug; 4(8):587-97.
Score: 0.007
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On the number of genealogical ancestors tracing to the source groups of an admixed population. Genetics. 2023 07 06; 224(3).
Score: 0.007
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Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy. Nat Commun. 2023 05 15; 14(1):2709.
Score: 0.007
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Precise modulation of transcription factor levels identifies features underlying dosage sensitivity. Nat Genet. 2023 05; 55(5):841-851.
Score: 0.007
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The allelic architecture of human disease genes: common disease-common variant...or not? Hum Mol Genet. 2002 Oct 01; 11(20):2417-23.
Score: 0.007
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RNA editing underlies genetic risk of common inflammatory diseases. Nature. 2022 08; 608(7923):569-577.
Score: 0.007
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Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks. Nat Genet. 2022 08; 54(8):1133-1144.
Score: 0.007
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A highly virulent variant of HIV-1 circulating in the Netherlands. Science. 2022 02 04; 375(6580):540-545.
Score: 0.007
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Case-control studies of association in structured or admixed populations. Theor Popul Biol. 2001 Nov; 60(3):227-37.
Score: 0.007
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Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nat Genet. 2021 09; 53(9):1300-1310.
Score: 0.006
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Linkage disequilibrium in humans: models and data. Am J Hum Genet. 2001 Jul; 69(1):1-14.
Score: 0.006
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Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet. 2001 Jul; 69(1):124-37.
Score: 0.006
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Shared heritability of human face and brain shape. Nat Genet. 2021 06; 53(6):830-839.
Score: 0.006
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A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density. Cell Metab. 2021 03 02; 33(3):615-628.e13.
Score: 0.006
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Genetics of 35 blood and urine biomarkers in the UK Biobank. Nat Genet. 2021 02; 53(2):185-194.
Score: 0.006
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Inference of population structure using multilocus genotype data. Genetics. 2000 Jun; 155(2):945-59.
Score: 0.006
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Association mapping in structured populations. Am J Hum Genet. 2000 Jul; 67(1):170-81.
Score: 0.006
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DNA analysis in a paternity case involving a triploid fetus. Transfusion. 2000 Feb; 40(2):240-4.
Score: 0.006
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Variable prediction accuracy of polygenic scores within an ancestry group. Elife. 2020 01 30; 9.
Score: 0.006
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Chromatin accessibility dynamics in a model of human forebrain development. Science. 2020 01 24; 367(6476).
Score: 0.006
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Population growth of human Y chromosomes: a study of Y chromosome microsatellites. Mol Biol Evol. 1999 Dec; 16(12):1791-8.
Score: 0.006
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Ancient Rome: A genetic crossroads of Europe and the Mediterranean. Science. 2019 11 08; 366(6466):708-714.
Score: 0.006
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Landscape of stimulation-responsive chromatin across diverse human immune cells. Nat Genet. 2019 10; 51(10):1494-1505.
Score: 0.006
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Use of unlinked genetic markers to detect population stratification in association studies. Am J Hum Genet. 1999 Jul; 65(1):220-8.
Score: 0.006
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Public Discussion Affects Question Asking at Academic Conferences. Am J Hum Genet. 2019 07 03; 105(1):189-197.
Score: 0.006
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Reduced signal for polygenic adaptation of height in UK Biobank. Elife. 2019 03 21; 8.
Score: 0.005
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High-resolution mapping of cancer cell networks using co-functional interactions. Mol Syst Biol. 2018 12 20; 14(12):e8594.
Score: 0.005
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Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes. Elife. 2018 05 08; 7.
Score: 0.005
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Impact of regulatory variation across human iPSCs and differentiated cells. Genome Res. 2018 01; 28(1):122-131.
Score: 0.005
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Quantification of transplant-derived circulating cell-free DNA in absence of a donor genotype. PLoS Comput Biol. 2017 Aug; 13(8):e1005629.
Score: 0.005
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Tracing the peopling of the world through genomics. Nature. 2017 01 18; 541(7637):302-310.
Score: 0.005
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Batch effects and the effective design of single-cell gene expression studies. Sci Rep. 2017 01 03; 7:39921.
Score: 0.005
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Genetic data and the African origin of humans. Science. 1996 Nov 29; 274(5292):1548-9.
Score: 0.005
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Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution. Nat Genet. 2016 10; 48(10):1193-203.
Score: 0.005
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Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs. PLoS Genet. 2016 Jan; 12(1):e1005793.
Score: 0.004
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Abundant contribution of short tandem repeats to gene expression variation in humans. Nat Genet. 2016 Jan; 48(1):22-9.
Score: 0.004
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msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding. PLoS One. 2015; 10(9):e0138030.
Score: 0.004
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Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions. Cell. 2015 Aug 27; 162(5):1051-65.
Score: 0.004
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Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature. PLoS Genet. 2015 May; 11(5):e1005216.
Score: 0.004
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The genetic and mechanistic basis for variation in gene regulation. PLoS Genet. 2015 Jan; 11(1):e1004857.
Score: 0.004
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Genomic variation. Impact of regulatory variation from RNA to protein. Science. 2015 Feb 06; 347(6222):664-7.
Score: 0.004
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Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels. PLoS Genet. 2014 Sep; 10(9):e1004663.
Score: 0.004
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The functional consequences of variation in transcription factor binding. PLoS Genet. 2014 Mar; 10(3):e1004226.
Score: 0.004
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The deleterious mutation load is insensitive to recent population history. Nat Genet. 2014 Mar; 46(3):220-4.
Score: 0.004
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Admixture facilitates genetic adaptations to high altitude in Tibet. Nat Commun. 2014; 5:3281.
Score: 0.004
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Epigenetic modifications are associated with inter-species gene expression variation in primates. Genome Biol. 2014; 15(12):547.
Score: 0.004
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Primate transcript and protein expression levels evolve under compensatory selection pressures. Science. 2013 Nov 29; 342(6162):1100-4.
Score: 0.004
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The genetic architecture of adaptations to high altitude in Ethiopia. PLoS Genet. 2012; 8(12):e1003110.
Score: 0.004
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The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels. PLoS Genet. 2012; 8(10):e1003000.
Score: 0.003
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Genomics: ENCODE explained. Nature. 2012 Sep 06; 489(7414):52-5.
Score: 0.003
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A systematic survey of loss-of-function variants in human protein-coding genes. Science. 2012 Feb 17; 335(6070):823-8.
Score: 0.003
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Comparative RNA sequencing reveals substantial genetic variation in endangered primates. Genome Res. 2012 Apr; 22(4):602-10.
Score: 0.003
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A genome sequence resource for the aye-aye (Daubentonia madagascariensis), a nocturnal lemur from Madagascar. Genome Biol Evol. 2012; 4(2):126-35.
Score: 0.003
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Haplotype variation and genotype imputation in African populations. Genet Epidemiol. 2011 Dec; 35(8):766-80.
Score: 0.003
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Adaptations to climate-mediated selective pressures in humans. PLoS Genet. 2011 Apr; 7(4):e1001375.
Score: 0.003
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A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues. PLoS Genet. 2011 Feb; 7(2):e1001316.
Score: 0.003
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Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency. Proc Natl Acad Sci U S A. 2010 May 11; 107 Suppl 2:8924-30.
Score: 0.003
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Characterizing natural variation using next-generation sequencing technologies. Trends Genet. 2009 Oct; 25(10):463-71.
Score: 0.003
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Haplotypic background of a private allele at high frequency in the Americas. Mol Biol Evol. 2009 May; 26(5):995-1016.
Score: 0.003
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Adaptations to climate in candidate genes for common metabolic disorders. PLoS Genet. 2008 Feb; 4(2):e32.
Score: 0.003
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High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science. 2008 Mar 07; 319(5868):1395-8.
Score: 0.003
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Adaptive drool in the gene pool. Nat Genet. 2007 Oct; 39(10):1188-90.
Score: 0.002
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Using population mixtures to optimize the utility of genomic databases: linkage disequilibrium and association study design in India. Ann Hum Genet. 2008 Jul; 72(Pt 4):535-46.
Score: 0.002
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Completing the map of human genetic variation. Nature. 2007 May 10; 447(7141):161-5.
Score: 0.002
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Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet. 2007 Jan; 39(1):31-40.
Score: 0.002
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Sequencing and analysis of Neanderthal genomic DNA. Science. 2006 Nov 17; 314(5802):1113-8.
Score: 0.002
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Long term morbidity and health related quality of life after multi-system Langerhans cell histiocytosis. Eur J Cancer. 2006 Oct; 42(15):2563-9.
Score: 0.002
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The effects of genotype-dependent recombination, and transmission asymmetry, on linkage disequilibrium. Genetics. 2006 Mar; 172(3):2001-5.
Score: 0.002
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Clines, clusters, and the effect of study design on the inference of human population structure. PLoS Genet. 2005 Dec; 1(6):e70.
Score: 0.002
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Evidence for extensive transmission distortion in the human genome. Am J Hum Genet. 2004 Jan; 74(1):62-72.
Score: 0.002
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Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics. 2003 Aug; 164(4):1567-87.
Score: 0.002
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Traces of human migrations in Helicobacter pylori populations. Science. 2003 Mar 07; 299(5612):1582-5.
Score: 0.002
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Genetic structure of human populations. Science. 2002 Dec 20; 298(5602):2381-5.
Score: 0.002
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Distinctive genetic signatures in the Libyan Jews. Proc Natl Acad Sci U S A. 2001 Jan 30; 98(3):858-63.
Score: 0.002
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Recent common ancestry of human Y chromosomes: evidence from DNA sequence data. Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13):7360-5.
Score: 0.001
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Defective alloantigen-presenting capacity of 'Langerhans cell histiocytosis cells'. Arch Dis Child. 1992 Nov; 67(11):1370-2.
Score: 0.001
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Documentation of Epstein-Barr virus infection in immunodeficient patients with life-threatening lymphoproliferative diseases by clinical, virological, and immunopathological studies. Cancer Res. 1981 Nov; 41(11 Pt 1):4226-36.
Score: 0.000