The University of Chicago Header Logo

Connection

Mark J. Ratain to Clinical Trials as Topic

This is a "connection" page, showing publications Mark J. Ratain has written about Clinical Trials as Topic.
Connection Strength

3.715
  1. Ethical Framework for Including Research Biopsies in Oncology Clinical Trials: American Society of Clinical Oncology Research Statement. J Clin Oncol. 2019 09 10; 37(26):2368-2377.
    View in: PubMed
    Score: 0.480
  2. Impact of the 2010 Consensus Recommendations of the Clinical Trial Design Task Force of the NCI Investigational Drug Steering Committee. Clin Cancer Res. 2015 Nov 15; 21(22):5057-63.
    View in: PubMed
    Score: 0.372
  3. RECIST: no longer the sharpest tool in the oncology clinical trials toolbox---point. Cancer Res. 2012 Oct 15; 72(20):5145-9; discussion 5150.
    View in: PubMed
    Score: 0.298
  4. Why RECIST works and why it should stay--reply to counterpoint. Cancer Res. 2012 Oct 15; 72(20):5158.
    View in: PubMed
    Score: 0.298
  5. Recommended changes to oncology clinical trial design: revolution or evolution? Eur J Cancer. 2008 Jan; 44(1):8-11.
    View in: PubMed
    Score: 0.213
  6. Phase II studies of modern drugs directed against new targets: if you are fazed, too, then resist RECIST. J Clin Oncol. 2004 Nov 15; 22(22):4442-5.
    View in: PubMed
    Score: 0.172
  7. Finding the right dose. Clin Adv Hematol Oncol. 2003 Sep; 1(9):517-8, 531.
    View in: PubMed
    Score: 0.159
  8. Clinical trial designs for cytostatic agents. J Clin Oncol. 2001 Jun 15; 19(12):3154-5.
    View in: PubMed
    Score: 0.137
  9. Conflict-of-interest policies. N Engl J Med. 2001 Mar 29; 344(13):1018.
    View in: PubMed
    Score: 0.135
  10. Development of target-based antineoplastic agents. Invest New Drugs. 2000 Feb; 18(1):7-16.
    View in: PubMed
    Score: 0.124
  11. Burdensome Research Procedures in Trials: Why Less Is More. J Natl Cancer Inst. 2017 04 01; 109(4).
    View in: PubMed
    Score: 0.102
  12. Tumour heterogeneity in the clinic. Nature. 2013 Sep 19; 501(7467):355-64.
    View in: PubMed
    Score: 0.080
  13. Effects of vascular endothelial growth factor signaling inhibition on human erythropoiesis. Oncologist. 2013; 18(8):965-70.
    View in: PubMed
    Score: 0.079
  14. Cancer pharmacogenomics: strategies and challenges. Nat Rev Genet. 2013 Jan; 14(1):23-34.
    View in: PubMed
    Score: 0.076
  15. Opportunities and challenges in the development of experimental drug combinations for cancer. J Natl Cancer Inst. 2011 Aug 17; 103(16):1222-6.
    View in: PubMed
    Score: 0.069
  16. Guidelines for the development and incorporation of biomarker studies in early clinical trials of novel agents. Clin Cancer Res. 2010 Mar 15; 16(6):1745-55.
    View in: PubMed
    Score: 0.063
  17. Biomarkers in early cancer drug development: limited utility. Clin Pharmacol Ther. 2009 Feb; 85(2):134-5.
    View in: PubMed
    Score: 0.058
  18. Pharmacogenetics and pharmacogenomics of anticancer agents. CA Cancer J Clin. 2009 Jan-Feb; 59(1):42-55.
    View in: PubMed
    Score: 0.058
  19. Pharmacogenetic pathway analysis of irinotecan. Clin Pharmacol Ther. 2008 Sep; 84(3):393-402.
    View in: PubMed
    Score: 0.055
  20. Ethical, scientific, and regulatory perspectives regarding the use of placebos in cancer clinical trials. J Clin Oncol. 2008 Mar 10; 26(8):1371-8.
    View in: PubMed
    Score: 0.054
  21. The investigational drug steering committee. Clin Adv Hematol Oncol. 2007 Oct; 5(10):779-80.
    View in: PubMed
    Score: 0.053
  22. Attitudes toward research participation and investigator conflicts of interest among advanced cancer patients participating in early phase clinical trials. J Clin Oncol. 2007 Aug 10; 25(23):3488-94.
    View in: PubMed
    Score: 0.052
  23. The value meal: how to save $1,700 per month or more on lapatinib. J Clin Oncol. 2007 Aug 10; 25(23):3397-8.
    View in: PubMed
    Score: 0.052
  24. Pharmacogenetics of irinotecan: clinical perspectives on the utility of genotyping. Pharmacogenomics. 2006 Dec; 7(8):1211-21.
    View in: PubMed
    Score: 0.050
  25. The cancer and leukemia group B pharmacology and experimental therapeutics committee: a historical perspective. Clin Cancer Res. 2006 Jun 01; 12(11 Pt 2):3612s-6s.
    View in: PubMed
    Score: 0.048
  26. Measuring response in a post-RECIST world: from black and white to shades of grey. Nat Rev Cancer. 2006 05; 6(5):409-14.
    View in: PubMed
    Score: 0.048
  27. Pharmacokinetic variability of anticancer agents. Nat Rev Cancer. 2005 Jun; 5(6):447-58.
    View in: PubMed
    Score: 0.045
  28. Pharmacogenomics: road to anticancer therapeutics nirvana? Oncogene. 2003 Sep 29; 22(42):6621-8.
    View in: PubMed
    Score: 0.040
  29. Screening for sources of interindividual pharmacokinetic variability in anticancer drug therapy: utility of population analysis. Cancer Invest. 2001; 19(1):57-64.
    View in: PubMed
    Score: 0.033
  30. Optimal Sampling Strategies for Irinotecan (CPT-11) and its Active Metabolite (SN-38) in Cancer Patients. AAPS J. 2020 03 17; 22(3):59.
    View in: PubMed
    Score: 0.031
  31. Drug combinations: dangerous liaisons or great expectations? Ann Oncol. 1999 Apr; 10(4):375-6.
    View in: PubMed
    Score: 0.029
  32. Identification of a Genomic Region between SLC29A1 and HSP90AB1 Associated with Risk of Bevacizumab-Induced Hypertension: CALGB 80405 (Alliance). Clin Cancer Res. 2018 10 01; 24(19):4734-4744.
    View in: PubMed
    Score: 0.028
  33. Measuring financial toxicity as a clinically relevant patient-reported outcome: The validation of the COmprehensive Score for financial Toxicity (COST). Cancer. 2017 02 01; 123(3):476-484.
    View in: PubMed
    Score: 0.025
  34. Comparative Effects of CT Imaging Measurement on RECIST End Points and Tumor Growth Kinetics Modeling. Clin Transl Sci. 2016 Feb; 9(1):43-50.
    View in: PubMed
    Score: 0.024
  35. Cancer pharmacogenomics and pharmacoepidemiology: setting a research agenda to accelerate translation. J Natl Cancer Inst. 2010 Nov 17; 102(22):1698-705.
    View in: PubMed
    Score: 0.016
  36. Vascular endothelial growth factor pathway. Pharmacogenet Genomics. 2010 May; 20(5):346-9.
    View in: PubMed
    Score: 0.016
  37. Relapse after interferon alfa-2b therapy for hairy-cell leukemia: analysis of prognostic variables. J Clin Oncol. 1988 Nov; 6(11):1714-21.
    View in: PubMed
    Score: 0.014
  38. Interpreting P values in pharmacogenetic studies: a call for process and perspective. J Clin Oncol. 2007 Oct 10; 25(29):4513-5.
    View in: PubMed
    Score: 0.013
  39. Interleukin-2 fusion protein: an investigational therapy for interleukin-2 receptor expressing malignancies. Eur J Cancer. 1997 Jan; 33 Suppl 1:S34-6.
    View in: PubMed
    Score: 0.006
  40. Randomized study of the duration of treatment with interferon alfa-2B in patients with hairy cell leukemia. J Natl Cancer Inst. 1988 May 04; 80(5):369-73.
    View in: PubMed
    Score: 0.003
  41. A programmable and implantable pumping system for systemic chemotherapy: a performance analysis in 52 patients. J Clin Oncol. 1987 Dec; 5(12):1968-76.
    View in: PubMed
    Score: 0.003
  42. Alpha-2 interferon therapy of hairy-cell leukemia: a multicenter study of 64 patients. J Clin Oncol. 1986 Jun; 4(6):900-5.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.