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Carole Ober to Genome-Wide Association Study

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This is a "connection" page, showing publications Carole Ober has written about Genome-Wide Association Study.
Carole Ober
Connection Strength
4.808
Genome-Wide Association Study
  1. Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings. PLoS Genet. 2023 01; 19(1):e1010594.
    View in: PubMed
    Score: 0.445
  2. Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region. Genome Med. 2022 05 24; 14(1):55.
    View in: PubMed
    Score: 0.426
  3. Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes. Clin Epigenetics. 2018; 10:62.
    View in: PubMed
    Score: 0.322
  4. Asthma Genetics in the Post-GWAS Era. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S85-90.
    View in: PubMed
    Score: 0.276
  5. Integrated analyses of gene expression and genetic association studies in a founder population. Hum Mol Genet. 2016 05 15; 25(10):2104-2112.
    View in: PubMed
    Score: 0.276
  6. Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways. Am J Respir Crit Care Med. 2016 Feb 15; 193(4):376-85.
    View in: PubMed
    Score: 0.276
  7. Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma. Nat Commun. 2015 Jan 16; 6:5965.
    View in: PubMed
    Score: 0.256
  8. Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q. J Lipid Res. 2009 May; 50(5):798-806.
    View in: PubMed
    Score: 0.168
  9. Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations. Genome Med. 2025 Apr 10; 17(1):35.
    View in: PubMed
    Score: 0.130
  10. Revealing polygenic pleiotropy using genetic risk scores for asthma. HGG Adv. 2023 10 12; 4(4):100233.
    View in: PubMed
    Score: 0.116
  11. New Insights Relating Gasdermin B to the Onset of Childhood Asthma. Am J Respir Cell Mol Biol. 2022 Oct; 67(4):430-437.
    View in: PubMed
    Score: 0.109
  12. African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans. Genome Med. 2022 09 29; 14(1):112.
    View in: PubMed
    Score: 0.109
  13. Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women. Alzheimers Dement. 2023 03; 19(3):896-908.
    View in: PubMed
    Score: 0.107
  14. Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma. J Allergy Clin Immunol. 2022 10; 150(4):972-978.e7.
    View in: PubMed
    Score: 0.106
  15. Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB. J Allergy Clin Immunol. 2022 09; 150(3):622-630.
    View in: PubMed
    Score: 0.105
  16. Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus. Genome Med. 2021 10 10; 13(1):157.
    View in: PubMed
    Score: 0.102
  17. Genome-wide association study identifies TNFSF15 associated with childhood asthma. Allergy. 2022 01; 77(1):218-229.
    View in: PubMed
    Score: 0.100
  18. Two-stage genome-wide association study of chronic rhinosinusitis and disease subphenotypes highlights mucosal immunity contributing to risk. Int Forum Allergy Rhinol. 2021 04; 11(4):814-817.
    View in: PubMed
    Score: 0.097
  19. Advances in asthma and allergic disease genetics: Is bigger always better? J Allergy Clin Immunol. 2019 12; 144(6):1495-1506.
    View in: PubMed
    Score: 0.089
  20. Parent-of-origin effects on quantitative phenotypes in a large Hutterite pedigree. Commun Biol. 2019; 2:28.
    View in: PubMed
    Score: 0.084
  21. Rare non-coding variants are associated with plasma lipid traits in a founder population. Sci Rep. 2017 11 27; 7(1):16415.
    View in: PubMed
    Score: 0.078
  22. Leveraging gene-environment interactions and endotypes for asthma gene discovery. J Allergy Clin Immunol. 2016 Mar; 137(3):667-79.
    View in: PubMed
    Score: 0.069
  23. Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma. PLoS One. 2014; 9(8):e104396.
    View in: PubMed
    Score: 0.062
  24. Genome-wide interaction studies reveal sex-specific asthma risk alleles. Hum Mol Genet. 2014 Oct 01; 23(19):5251-9.
    View in: PubMed
    Score: 0.061
  25. Genome-wide association study of lung function phenotypes in a founder population. J Allergy Clin Immunol. 2014 Jan; 133(1):248-55.e1-10.
    View in: PubMed
    Score: 0.058
  26. Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases. J Allergy Clin Immunol. 2012 Oct; 130(4):861-8.e7.
    View in: PubMed
    Score: 0.053
  27. Genome-wide association study identifies candidate genes for male fertility traits in humans. Am J Hum Genet. 2012 Jun 08; 90(6):950-61.
    View in: PubMed
    Score: 0.053
  28. Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects. J Allergy Clin Immunol. 2012 Sep; 130(3):622-629.e9.
    View in: PubMed
    Score: 0.053
  29. Resequencing candidate genes implicates rare variants in asthma susceptibility. Am J Hum Genet. 2012 Feb 10; 90(2):273-81.
    View in: PubMed
    Score: 0.052
  30. The genetics of asthma and allergic disease: a 21st century perspective. Immunol Rev. 2011 Jul; 242(1):10-30.
    View in: PubMed
    Score: 0.050
  31. Gene-environment interactions in human disease: nuisance or opportunity? Trends Genet. 2011 Mar; 27(3):107-15.
    View in: PubMed
    Score: 0.048
  32. Genetic characterization of preschool wheeze phenotypes. J Allergy Clin Immunol. 2025 Dec; 156(6):1537-1546.
    View in: PubMed
    Score: 0.033
  33. Newborn blood DNA methylation and childhood asthma: findings from the ECHO program. Int J Epidemiol. 2025 Apr 12; 54(3).
    View in: PubMed
    Score: 0.032
  34. EndoPRS: Incorporating endophenotype information to improve polygenic risk scores for clinical endpoints-A study in asthma. Am J Hum Genet. 2025 May 01; 112(5):1199-1214.
    View in: PubMed
    Score: 0.032
  35. Gene-based association study of rare variants in children of diverse ancestries implicates TNFRSF21 in the development of allergic asthma. J Allergy Clin Immunol. 2024 Mar; 153(3):809-820.
    View in: PubMed
    Score: 0.029
  36. A functional genomics pipeline to identify high-value asthma and allergy CpGs in the human methylome. J Allergy Clin Immunol. 2023 06; 151(6):1609-1621.
    View in: PubMed
    Score: 0.028
  37. Discerning asthma endotypes through comorbidity mapping. Nat Commun. 2022 11 07; 13(1):6712.
    View in: PubMed
    Score: 0.027
  38. Multiethnic genome-wide and HLA association study of total serum IgE level. J Allergy Clin Immunol. 2021 12; 148(6):1589-1595.
    View in: PubMed
    Score: 0.025
  39. A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci. Nat Commun. 2021 09 06; 12(1):5253.
    View in: PubMed
    Score: 0.025
  40. FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses. Nat Commun. 2020 12 16; 11(1):6398.
    View in: PubMed
    Score: 0.024
  41. Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth. Sci Adv. 2020 12; 6(49).
    View in: PubMed
    Score: 0.024
  42. Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study. Eur Respir J. 2020 09; 56(3).
    View in: PubMed
    Score: 0.024
  43. Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma. Genome Med. 2020 07 20; 12(1):64.
    View in: PubMed
    Score: 0.023
  44. Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. Lancet Respir Med. 2019 06; 7(6):509-522.
    View in: PubMed
    Score: 0.021
  45. Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nat Genet. 2018 01; 50(1):42-53.
    View in: PubMed
    Score: 0.020
  46. Expression Quantitative Trait Locus Mapping Studies in Mid-secretory Phase Endometrial Cells Identifies HLA-F and TAP2 as Fecundability-Associated Genes. PLoS Genet. 2016 07; 12(7):e1005858.
    View in: PubMed
    Score: 0.018
  47. Genome-Wide Association Studies of the Human Gut Microbiota. PLoS One. 2015; 10(11):e0140301.
    View in: PubMed
    Score: 0.017
  48. A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. J Allergy Clin Immunol. 2013 Apr; 131(4):1176-84.
    View in: PubMed
    Score: 0.014
  49. Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. J Allergy Clin Immunol. 2012 Dec; 130(6):1294-301.
    View in: PubMed
    Score: 0.014
  50. Accurate imputation of rare and common variants in a founder population from a small number of sequenced individuals. Genet Epidemiol. 2012 May; 36(4):312-9.
    View in: PubMed
    Score: 0.013
  51. The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. Hum Mol Genet. 2012 May 01; 21(9):2111-23.
    View in: PubMed
    Score: 0.013
  52. Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet. 2011 Jul 31; 43(9):887-92.
    View in: PubMed
    Score: 0.013
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.