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Connection

Carole Ober to Genetic Predisposition to Disease

This is a "connection" page, showing publications Carole Ober has written about Genetic Predisposition to Disease.
  1. Leveraging gene-environment interactions and endotypes for asthma gene discovery. J Allergy Clin Immunol. 2016 Mar; 137(3):667-79.
    View in: PubMed
    Score: 0.283
  2. Asthma Genetics in the Post-GWAS Era. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S85-90.
    View in: PubMed
    Score: 0.283
  3. Integrated analyses of gene expression and genetic association studies in a founder population. Hum Mol Genet. 2016 05 15; 25(10):2104-2112.
    View in: PubMed
    Score: 0.283
  4. IFNG genotype and sex interact to influence the risk of childhood asthma. J Allergy Clin Immunol. 2011 Sep; 128(3):524-31.
    View in: PubMed
    Score: 0.206
  5. A genomewide screen for chronic rhinosinusitis genes identifies a locus on chromosome 7q. Laryngoscope. 2008 Nov; 118(11):2067-72.
    View in: PubMed
    Score: 0.170
  6. A genome-wide screen for hyposmia susceptibility Loci. Chem Senses. 2008 Apr; 33(4):319-29.
    View in: PubMed
    Score: 0.162
  7. Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci. J Allergy Clin Immunol. 2006 Aug; 118(2):396-402.
    View in: PubMed
    Score: 0.144
  8. The sex-specific genetic architecture of quantitative traits in humans. Nat Genet. 2006 Feb; 38(2):218-22.
    View in: PubMed
    Score: 0.140
  9. Rethinking genetic models of asthma: the role of environmental modifiers. Curr Opin Immunol. 2005 Dec; 17(6):670-8.
    View in: PubMed
    Score: 0.138
  10. Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. Am J Hum Genet. 2005 Feb; 76(2):349-57.
    View in: PubMed
    Score: 0.130
  11. Are common disease susceptibility alleles the same in outbred and founder populations? Eur J Hum Genet. 2004 Jul; 12(7):584-90.
    View in: PubMed
    Score: 0.126
  12. African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans. Genome Med. 2022 09 29; 14(1):112.
    View in: PubMed
    Score: 0.112
  13. Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women. Alzheimers Dement. 2023 03; 19(3):896-908.
    View in: PubMed
    Score: 0.110
  14. Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region. Genome Med. 2022 05 24; 14(1):55.
    View in: PubMed
    Score: 0.109
  15. Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus. Genome Med. 2021 10 10; 13(1):157.
    View in: PubMed
    Score: 0.104
  16. A second-generation genomewide screen for asthma-susceptibility alleles in a founder population. Am J Hum Genet. 2000 Nov; 67(5):1154-62.
    View in: PubMed
    Score: 0.097
  17. Expression quantitative trait locus fine mapping of the 17q12-21 asthma locus in African American children: a genetic association and gene expression study. Lancet Respir Med. 2020 05; 8(5):482-492.
    View in: PubMed
    Score: 0.094
  18. Advances in asthma and allergic disease genetics: Is bigger always better? J Allergy Clin Immunol. 2019 12; 144(6):1495-1506.
    View in: PubMed
    Score: 0.091
  19. Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. Lancet Respir Med. 2019 06; 7(6):509-522.
    View in: PubMed
    Score: 0.088
  20. Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma. Nat Commun. 2015 Jan 16; 6:5965.
    View in: PubMed
    Score: 0.065
  21. Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma. PLoS One. 2014; 9(8):e104396.
    View in: PubMed
    Score: 0.064
  22. Genome-wide interaction studies reveal sex-specific asthma risk alleles. Hum Mol Genet. 2014 Oct 01; 23(19):5251-9.
    View in: PubMed
    Score: 0.062
  23. Genome-wide association study of lung function phenotypes in a founder population. J Allergy Clin Immunol. 2014 Jan; 133(1):248-55.e1-10.
    View in: PubMed
    Score: 0.059
  24. The maternal HLA-G 1597?C null mutation is associated with increased risk of pre-eclampsia and reduced HLA-G expression during pregnancy in African-American women. Mol Hum Reprod. 2013 Mar; 19(3):144-52.
    View in: PubMed
    Score: 0.056
  25. Increased protein-coding mutations in the mitochondrial genome of African American women with preeclampsia. Reprod Sci. 2012 Dec; 19(12):1343-51.
    View in: PubMed
    Score: 0.055
  26. Resequencing candidate genes implicates rare variants in asthma susceptibility. Am J Hum Genet. 2012 Feb 10; 90(2):273-81.
    View in: PubMed
    Score: 0.053
  27. Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet. 2011 Jul 31; 43(9):887-92.
    View in: PubMed
    Score: 0.051
  28. The genetics of asthma and allergic disease: a 21st century perspective. Immunol Rev. 2011 Jul; 242(1):10-30.
    View in: PubMed
    Score: 0.051
  29. Gene-environment interactions in human disease: nuisance or opportunity? Trends Genet. 2011 Mar; 27(3):107-15.
    View in: PubMed
    Score: 0.050
  30. Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility. J Allergy Clin Immunol. 2009 Dec; 124(6):1204-9.e9.
    View in: PubMed
    Score: 0.046
  31. Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q. J Lipid Res. 2009 May; 50(5):798-806.
    View in: PubMed
    Score: 0.043
  32. Sex-specific genetic architecture of human disease. Nat Rev Genet. 2008 Dec; 9(12):911-22.
    View in: PubMed
    Score: 0.043
  33. Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. N Engl J Med. 2008 Apr 17; 358(16):1682-91.
    View in: PubMed
    Score: 0.041
  34. Allele-specific targeting of microRNAs to HLA-G and risk of asthma. Am J Hum Genet. 2007 Oct; 81(4):829-34.
    View in: PubMed
    Score: 0.039
  35. Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life. J Allergy Clin Immunol. 2007 Jun; 119(6):1423-9.
    View in: PubMed
    Score: 0.039
  36. Sex-specific genetic architecture of asthma-associated quantitative trait loci in a founder population. Curr Allergy Asthma Rep. 2006 May; 6(3):241-6.
    View in: PubMed
    Score: 0.036
  37. Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy. Respir Res. 2005 Dec 10; 6:145.
    View in: PubMed
    Score: 0.035
  38. Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations. Am J Respir Crit Care Med. 2005 Jul 01; 172(1):67-73.
    View in: PubMed
    Score: 0.033
  39. Gene-environment interaction effects on the development of immune responses in the 1st year of life. Am J Hum Genet. 2005 Apr; 76(4):696-704.
    View in: PubMed
    Score: 0.033
  40. Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus. Am J Hum Genet. 2003 Sep; 73(3):612-26.
    View in: PubMed
    Score: 0.030
  41. New Insights Relating Gasdermin B to the Onset of Childhood Asthma. Am J Respir Cell Mol Biol. 2022 Oct; 67(4):430-437.
    View in: PubMed
    Score: 0.028
  42. Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB. J Allergy Clin Immunol. 2022 09; 150(3):622-630.
    View in: PubMed
    Score: 0.027
  43. Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region. Nat Commun. 2021 10 21; 12(1):6115.
    View in: PubMed
    Score: 0.026
  44. Multiethnic genome-wide and HLA association study of total serum IgE level. J Allergy Clin Immunol. 2021 12; 148(6):1589-1595.
    View in: PubMed
    Score: 0.026
  45. Genome-wide association study identifies TNFSF15 associated with childhood asthma. Allergy. 2022 01; 77(1):218-229.
    View in: PubMed
    Score: 0.026
  46. Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children. J Allergy Clin Immunol. 2021 12; 148(6):1505-1514.
    View in: PubMed
    Score: 0.025
  47. FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses. Nat Commun. 2020 12 16; 11(1):6398.
    View in: PubMed
    Score: 0.025
  48. Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nat Genet. 2018 01; 50(1):42-53.
    View in: PubMed
    Score: 0.020
  49. Expression Quantitative Trait Locus Mapping Studies in Mid-secretory Phase Endometrial Cells Identifies HLA-F and TAP2 as Fecundability-Associated Genes. PLoS Genet. 2016 07; 12(7):e1005858.
    View in: PubMed
    Score: 0.018
  50. Rhinovirus wheezing illness and genetic risk of childhood-onset asthma. N Engl J Med. 2013 Apr 11; 368(15):1398-407.
    View in: PubMed
    Score: 0.014
  51. Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. J Allergy Clin Immunol. 2012 Dec; 130(6):1294-301.
    View in: PubMed
    Score: 0.014
  52. The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. Hum Mol Genet. 2012 May 01; 21(9):2111-23.
    View in: PubMed
    Score: 0.013
  53. ITGB3 shows genetic and expression interaction with SLC6A4. Hum Genet. 2006 Aug; 120(1):93-100.
    View in: PubMed
    Score: 0.009
  54. Variation in ITGB3 is associated with whole-blood serotonin level and autism susceptibility. Eur J Hum Genet. 2006 Aug; 14(8):923-31.
    View in: PubMed
    Score: 0.009
  55. Cutting edge: polymorphisms in the ICOS promoter region are associated with allergic sensitization and Th2 cytokine production. J Immunol. 2005 Aug 15; 175(4):2061-5.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.