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Emil F. Coccaro

TitleProfessor
InstitutionUniversity of Chicago
DepartmentPsychiatry & Behav. Neurosci
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Clinical Interests
    Mood, Anxiety, and Personality Disorders
    Intermittent Explosive Disorder
    Neuropsychopharmacology

    Research Interests
    Neuropsychopharmacologic and genetic mechanisms in major mood, anxiety, and personality disorders.
    Neurobiology of suicidal and impulsive aggressive behaviors.
    Brain-behavior relationships with regard to central neurotransmitter function.

    Collapse Biography 
    Collapse education and training
    New York University School of MedicineMD1979
    University of Cincinnati Medical CenterPGY-I1980Internal Medicine
    The Mount Sinai Medical Center, New YorkPGY-II/III1982General Adult Psychiatry
    Bronx Veterans Administration Hospital The Mount Sinai Medical Center , New YorkPGY-IV1983General Adult Psychiatry / Research, Outpatient Service
    American Board of Psychiatry and NeurologyBoard CertifiedAdult, General

    Collapse Research 
    Collapse research activities and funding
    R01MH133925     (COCCARO, EMIL FRANK)Jul 11, 2024 - Mar 31, 2029
    NIH
    Inflammatory Challenge in Human Aggression
    Role: Principal Investigator
    R34AA030919     (MCCLOSKEY, MICHAEL S)Mar 7, 2024 - Feb 28, 2027
    NIH
    Development of an Integrated Psychosocial Intervention for Alcohol Use Disorder with Comorbid Aggression
    Role: Co-Principal Investigator
    R01DK135948     (COCCARO, EMIL FRANK)Feb 1, 2024 - Jan 31, 2027
    NIH
    Development of a Group Emotion-Focused Behavioral Intervention for Diabetes Distress and Glycemic Management in Patients with T2D.
    Role: Principal Investigator
    R21MH119531     (COCCARO, EMIL FRANK)Sep 1, 2020 - Aug 31, 2022
    NIH
    Nitrous Oxide and Cortico-Limbic Function in Aggression
    Role: Principal Investigator
    R01AA026664     (COCCARO, EMIL FRANK ;KING, ANDREA C)Sep 5, 2018 - Aug 31, 2023
    NIH
    Aggression and SEIP: Neural Correlates During Alcohol Intoxication
    Role: Principal Investigator
    R01MH104673     (COCCARO, EMIL FRANK)Aug 13, 2015 - Jul 31, 2020
    NIH
    Neuroinflammation and Aggression
    Role: Principal Investigator
    R21MH099393     (COCCARO, EMIL FRANK)Jul 16, 2013 - Dec 31, 2015
    NIH
    Development of fMRI Studies of Social-Emotional Information Processing
    Role: Principal Investigator
    R01MH084904     (COCCARO, EMIL FRANK)Aug 25, 2010 - Jul 31, 2015
    NIH
    SSRIs and Self-harm in Borderline Personality Disorder
    Role: Principal Investigator
    R21MH083198     (COCCARO, EMIL FRANK)Jan 15, 2009 - May 31, 2012
    NIH
    Development of Pharmaco fMRI Challenge in Healthy Control and Aggressive Subjects
    Role: Principal Investigator
    R01MH080109     (COCCARO, EMIL FRANK)Apr 16, 2008 - Mar 31, 2014
    NIH
    Understanding The Pathways To Aggression
    Role: Principal Investigator
    R21MH073811     (COCCA, EMIL FRANK)Mar 1, 2006 - Feb 28, 2009
    NIH
    Social Information Processing: Assessment Development
    Role: Co-Principal Investigator
    R01MH066984     (COCCA, EMIL FRANK)May 15, 2003 - Apr 30, 2009
    NIH
    Fluoxetine and Divalproex:Treatment Correlates in Intermittent Explosive Disorder
    Role: Co-Principal Investigator
    R01MH063262     (COCCA, EMIL FRANK)Sep 9, 2002 - Jun 30, 2008
    NIH
    Impulsive Aggression : A Twin Study of Behavior and 5-HT
    Role: Co-Principal Investigator
    R01MH060836     (COCCA, EMIL FRANK)Sep 10, 2001 - Aug 31, 2007
    NIH
    Intermittent Explosive Disorder: A Family Study
    Role: Co-Principal Investigator
    R01MH054804     (COCCARO, EMIL F)May 1, 1996 - Apr 30, 2002
    NIH
    SPOUSAL ABUSE--SEROTONERGIC STUDIES AND TREATMENT
    Role: Principal Investigator
    R01MH047495     (COCCARO, EMIL F)May 1, 1992 - Apr 30, 2003
    NIH
    SEROTONIN AND IMPULSIVE AGGRESSION--TREATMENT CORRELATES
    Role: Principal Investigator
    K02MH000951     (COCCARO, EMIL F)Sep 30, 1991 - Apr 30, 2002
    NIH
    IMPULSIVE AGGRESSION--BIOLOGIC AND TREATMENT CORRELATES
    Role: Principal Investigator
    R01MH046948     (COCCARO, EMIL F)Apr 1, 1991 - Apr 30, 2002
    NIH
    IMPULSIVE AGGRESSION--5 HT AND NE CORRELATES
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ciesinski NK, McCloskey MS, Coccaro EF. A latent class analysis of cognitive-affective heterogeneity in current intermittent explosive disorder. J Affect Disord. 2024 Oct 15; 363:230-238. PMID: 39047949; PMCID: PMC11343643.
      Citations:    Fields:    Translation:Humans
    2. Timmins MA, Berman ME, Coccaro EF. Comparing behavioral measures of aggression in the laboratory: Taylor Aggression Paradigm versus Point-Subtraction Aggression Paradigm. Aggress Behav. 2024 Jun; 50(4):e22167. PMID: 39073143.
      Citations:    Fields:    Translation:Humans
    3. Meruelo AD, Brumback T, Pelham WE, Wade NE, Thomas ML, Coccaro EF, Nooner KB, Brown SA, Tapert SF, Mrug S. How Do Anger and Impulsivity Impact Fast-Food Consumption in Transitional Age Youth? AJPM Focus. 2024 Jun; 3(3):100208. PMID: 38560402; PMCID: PMC10981031.
      Citations:    
    4. Bryan CJ, Daruwala SE, Tabares JV, Butner JE, Coccaro EF, Gorka SM. Heightened threat perceptions and reduced stability in anxiety and fear among U.S. adults who carry handguns. J Anxiety Disord. 2023 10; 99:102764. PMID: 37597342; PMCID: PMC10543589.
      Citations:    Fields:    Translation:Humans
    5. Timmins MA, Fanning JR, McCloskey MS, Berman ME, Coccaro EF. Laboratory assessment of aggression: The Taylor Aggression Paradigm in adults with and without a disorder of impulsive aggression. J Psychiatr Res. 2023 07; 163:413-420. PMID: 37276645.
      Citations:    Fields:    Translation:Humans
    6. Meruelo AD, Timmins MA, Irwin MR, Coccaro EF. Salivary cortisol awakening levels are reduced in human subjects with intermittent explosive disorder compared with controls. Psychoneuroendocrinology. 2023 05; 151:106070. PMID: 36863129; PMCID: PMC10262314.
      Citations:    Fields:    Translation:Humans
    7. Coccaro EF, Lee R, Breen EC, Irwin MR. Plasma and cerebrospinal fluid inflammatory markers and human aggression. Neuropsychopharmacology. 2023 06; 48(7):1060-1066. PMID: 36804488; PMCID: PMC10209212.
      Citations: 2     Fields:    Translation:Humans
    8. Shevidi S, Timmins MA, Coccaro EF. Childhood and parental characteristics of adults with DSM-5 intermittent explosive disorder compared with healthy and psychiatric controls. Compr Psychiatry. 2023 04; 122:152367. PMID: 36774803; PMCID: PMC10262303.
      Citations:    Fields:    Translation:Humans
    9. Timmins MA, Berman ME, Coccaro EF. Life history of experienced and witnessed aggression: Development of a new assessment instrument. J Psychiatr Res. 2022 11; 155:518-525. PMID: 36191520.
      Citations: 1     Fields:    Translation:Humans
    10. Singer J, Cummings C, Coccaro EF. Parental separation and death during childhood as predictors of adult psychopathology: An examination of racial differences. Psychol Trauma. 2024 Feb; 16(2):184-192. PMID: 35737525; PMCID: PMC10262299.
      Citations: 1     Fields:    Translation:Humans
    11. Southward MW, Cheavens JS, Coccaro EF. Defining the p-factor: an empirical test of five leading theories. Psychol Med. 2023 May; 53(7):2732-2743. PMID: 35711145; PMCID: PMC10235655.
      Citations: 5     Fields:    Translation:Humans
    12. Moley JP, Norman JL, Coccaro EF. Personality disorder and mild traumatic brain injury. Personal Ment Health. 2022 11; 16(4):331-337. PMID: 35598165; PMCID: PMC9675684.
      Citations: 2     Fields:    Translation:Humans
    13. McCloskey MS, Chen EY, Olino TM, Coccaro EF. Cognitive-Behavioral Versus Supportive Psychotherapy for Intermittent Explosive Disorder: A Randomized Controlled Trial. Behav Ther. 2022 11; 53(6):1133-1146. PMID: 36229112.
      Citations: 3     Fields:    Translation:Humans
    14. Coccaro EF, Keedy S, Malina M, Lee R, Phan KL. Neuronal responses in social-emotional information processing in impulsive aggressive individuals. Neuropsychopharmacology. 2022 05; 47(6):1249-1255. PMID: 35277651; PMCID: PMC9018744.
      Citations: 1     Fields:    Translation:Humans
    15. Coccaro EF, Drossos T, Kline D, Lazarus S, Joseph JJ, de Groot M. Diabetes distress, emotional regulation, HbA1c in people with diabetes and A controlled pilot study of an emotion-focused behavioral therapy intervention in adults with type 2 diabetes. Prim Care Diabetes. 2022 06; 16(3):381-386. PMID: 35288059; PMCID: PMC9133204.
      Citations: 2     Fields:    Translation:Humans
    16. Shima C, Lee R, Coccaro EF. Associations of agression and use of caffeine, alcohol and nicotine in healthy and aggressive individuals. J Psychiatr Res. 2022 02; 146:21-27. PMID: 34942448.
      Citations:    Fields:    Translation:Humans
    17. Coccaro EF, Irwin M, Arevalo JMG, Dizon T, Cole S. Gene expression in peripheral blood mononuclear cells in impulsive aggression: Intermittent explosive disorder compared with non-aggressive healthy and psychiatric controls. Psychoneuroendocrinology. 2022 02; 136:105453. PMID: 34864503.
      Citations: 1     Fields:    Translation:HumansCells
    18. Hall OT, Coccaro EF. Assessment of subjective sleep quality and issues in aggression: Intermittent Explosive Disorder compared with psychiatric and healthy controls. Compr Psychiatry. 2022 01; 112:152270. PMID: 34702562.
      Citations:    Fields:    Translation:Humans
    19. Ogbuagu N, Keedy S, Phan KL, Coccaro EF. Neural responses to induced emotion and response to social threat in intermittent explosive disorder. Psychiatry Res Neuroimaging. 2021 12 30; 318:111388. PMID: 34706324.
      Citations: 1     Fields:    Translation:Humans
    20. Krick LC, Berman ME, McCloskey MS, Coccaro EF, Fanning JR. Gender Moderates the Association Between Exposure to Interpersonal Violence and Intermittent Explosive Disorder Diagnosis. J Interpers Violence. 2022 08; 37(15-16):NP14746-NP14771. PMID: 33977809.
      Citations:    Fields:    Translation:Humans
    21. Fahlgren MK, Cheung JC, Ciesinski NK, McCloskey MS, Coccaro EF. Gender Differences in the Relationship between Anger and Aggressive Behavior. J Interpers Violence. 2022 07; 37(13-14):NP12661-NP12670. PMID: 33546562.
      Citations: 5     Fields:    Translation:Humans
    22. Patoilo MS, Berman ME, Coccaro EF. Emotion attribution in intermittent explosive disorder. Compr Psychiatry. 2021 04; 106:152229. PMID: 33662604.
      Citations: 2     Fields:    Translation:Humans
    23. Coccaro EF, Keedy S, Lee R, Phan KL. Neuronal responses to adverse social threat in healthy human subjects. J Psychiatr Res. 2021 04; 136:47-53. PMID: 33556904; PMCID: PMC10262305.
      Citations: 2     Fields:    Translation:Humans
    24. Coccaro EF, Lazarus S, Joseph J, Wyne K, Drossos T, Phillipson L, de Groot M. Emotional Regulation and Diabetes Distress in Adults With Type 1 and Type 2 Diabetes. Diabetes Care. 2021 01; 44(1):20-25. PMID: 33444157; PMCID: PMC8742145.
      Citations: 14     Fields:    Translation:Humans
    25. Cremers H, Keedy S, Coccaro E. The development of an fMRI protocol to investigate vmPFC network functioning underlying the generalization of behavioral control. Psychiatry Res Neuroimaging. 2021 01 30; 307:111197. PMID: 33077339.
      Citations: 2     Fields:    Translation:HumansAnimals
    26. Radwan K, Coccaro EF. Comorbidity of disruptive behavior disorders and intermittent explosive disorder. Child Adolesc Psychiatry Ment Health. 2020; 14:24. PMID: 32514306; PMCID: PMC7257202.
      Citations: 3     
    27. Coccaro EF, Lee RJ. Disordered Aggression and Violence in the United States. J Clin Psychiatry. 2020 03 17; 81(2). PMID: 32220154.
      Citations: 5     Fields:    Translation:Humans
    28. Lee RJ, Gozal D, Coccaro EF, Fanning J. Narcissistic and Borderline Personality Disorders: Relationship With Oxidative Stress. J Pers Disord. 2020 03; 34(Suppl):6-24. PMID: 32186978.
      Citations: 8     Fields:    Translation:Humans
    29. Puhalla AA, Berman ME, Coccaro EF, Fahlgren MK, McCloskey MS. History of childhood abuse and alcohol use disorder: Relationship with intermittent explosive disorder and intoxicated aggression frequency. J Psychiatr Res. 2020 06; 125:38-44. PMID: 32203738.
      Citations: 5     Fields:    Translation:Humans
    30. Coccaro EF. The Overt Aggression Scale Modified (OAS-M) for clinical trials targeting impulsive aggression and intermittent explosive disorder: Validity, reliability, and correlates. J Psychiatr Res. 2020 05; 124:50-57. PMID: 32114032.
      Citations: 8     Fields:    Translation:Humans
    31. Coccaro EF, Lee RJ. 5-HT2c agonist, lorcaserin, reduces aggressive responding in intermittent explosive disorder: A pilot study. Hum Psychopharmacol. 2019 11; 34(6):e2714. PMID: 31774584.
      Citations: 3     Fields:    Translation:Humans
    32. Fanning JR, Marcus DK, Preszler JR, Coccaro EF. Evidence for the taxonic latent structure for DSM-5 intermittent explosive disorder in adults. Psychol Med. 2021 01; 51(1):54-61. PMID: 31680661.
      Citations:    Fields:    Translation:Humans
    33. Heilman P, Hill MN, Coussons-Read M, Brundin L, Coccaro EF. Role of the kynurenine pathway and the endocannabinoid system as modulators of inflammation and personality traits. Psychoneuroendocrinology. 2019 12; 110:104434. PMID: 31525567; PMCID: PMC10262304.
      Citations: 6     Fields:    Translation:HumansCells
    34. Coccaro EF. New Hope for Patients with Major Depressive Disorder? N Engl J Med. 2019 09 05; 381(10):980-981. PMID: 31483972.
      Citations: 3     Fields:    Translation:Humans
    35. Coccaro EF. Psychiatric comorbidity in Intermittent Explosive Disorder. J Psychiatr Res. 2019 11; 118:38-43. PMID: 31487607; PMCID: PMC10262302.
      Citations: 3     Fields:    Translation:Humans
    36. Medeiros GC, Kim HS, Coccaro EF, Seger-Jacob L, Garreto AK, Tavares H. Aggression directed towards others vs. aggression directed towards the self: clinical differences between intermittent explosive disorder and nonsuicidal self-injury. Braz J Psychiatry. 2019 Jul-Aug; 41(4):303-309. PMID: 30843959; PMCID: PMC6804311.
      Citations:    Fields:    Translation:Humans
    37. Ammerman BA, Sorgi KM, Berman ME, Coccaro EF, McCloskey MS. Potential Mood Variation Following a Behavioral Analogue of Self-Injurious Behavior. Arch Suicide Res. 2020; 24(sup2):S113-S125. PMID: 30300119; PMCID: PMC6531373.
      Citations: 1     Fields:    Translation:Humans
    38. Fanning JR, Coleman M, Lee R, Coccaro EF. Subtypes of aggression in intermittent explosive disorder. J Psychiatr Res. 2019 02; 109:164-172. PMID: 30551023; PMCID: PMC6699742.
      Citations: 5     Fields:    Translation:Humans
    39. Steakley-Freeman DM, Lee RJ, McCloskey MS, Coccaro EF. Social desirability, deceptive reporting, and awareness of problematic aggression in intermittent explosive disorder compared with non-aggressive healthy and psychiatric controls. Psychiatry Res. 2018 12; 270:20-25. PMID: 30243128.
      Citations: 1     Fields:    Translation:Humans
    40. Coccaro EF, Shima CK, Lee RJ. Comorbidity of personality disorder with intermittent explosive disorder. J Psychiatr Res. 2018 11; 106:15-21. PMID: 30240963.
      Citations: 8     Fields:    Translation:Humans
    41. Coccaro EF. DSM-5 intermittent explosive disorder: Relationship with Disruptive Mood Dysregulation Disorder. Compr Psychiatry. 2018 07; 84:118-121. PMID: 29753187.
      Citations: 2     Fields:    Translation:Humans
    42. Rynar L, Coccaro EF. Psychosocial impairment in DSM-5 intermittent explosive disorder. Psychiatry Res. 2018 06; 264:91-95. PMID: 29627702; PMCID: PMC5983894.
      Citations: 6     Fields:    Translation:Humans
    43. Coccaro EF, Hill MN, Robinson L, Lee RJ. Circulating endocannabinoids and affect regulation in human subjects. Psychoneuroendocrinology. 2018 06; 92:66-71. PMID: 29627714.
      Citations: 11     Fields:    Translation:Humans
    44. Mosti C, Coccaro EF. Mild Traumatic Brain Injury and Aggression, Impulsivity, and History of Other- and Self-Directed Aggression. J Neuropsychiatry Clin Neurosci. 2018; 30(3):220-227. PMID: 29505319; PMCID: PMC6081254.
      Citations: 9     Fields:    Translation:Humans
    45. Montalvo-Ortiz JL, Zhang H, Chen C, Liu C, Coccaro EF. Genome-Wide DNA Methylation Changes Associated with Intermittent Explosive Disorder: A Gene-Based Functional Enrichment Analysis. Int J Neuropsychopharmacol. 2018 01 01; 21(1):12-20. PMID: 29106553; PMCID: PMC5789263.
      Citations: 2     Fields:    Translation:HumansCells
    46. Coccaro EF, Cremers H, Fanning J, Nosal E, Lee R, Keedy S, Jacobson KC. Reduced frontal grey matter, life history of aggression, and underlying genetic influence. Psychiatry Res Neuroimaging. 2018 01 30; 271:126-134. PMID: 29174436.
      Citations: 5     Fields:    Translation:Humans
    47. Coccaro EF. Testosterone and Aggression: More Than Just Biology? Biol Psychiatry. 2017 08 15; 82(4):234. PMID: 28748784.
      Citations: 1     Fields:    Translation:Humans
    48. Coccaro EF, Fanning JR, Lee R. Intermittent Explosive Disorder and Substance Use Disorder: Analysis of the National Comorbidity Survey Replication Sample. J Clin Psychiatry. 2017 Jun; 78(6):697-702. PMID: 28252880; PMCID: PMC6128355.
      Citations: 9     Fields:    Translation:Humans
    49. Fanning JR, Keedy S, Berman ME, Lee R, Coccaro EF. Neural Correlates of Aggressive Behavior in Real Time: a Review of fMRI Studies of Laboratory Reactive Aggression. Curr Behav Neurosci Rep. 2017 Jun; 4(2):138-150. PMID: 29607288; PMCID: PMC5875983.
      Citations: 23     
    50. Jennings KM, Wildes JE, Coccaro EF. Intermittent explosive disorder and eating disorders: Analysis of national comorbidity and research samples. Compr Psychiatry. 2017 05; 75:62-67. PMID: 28324677; PMCID: PMC5410643.
      Citations: 4     Fields:    Translation:Humans
    51. Kass AE, Wildes JE, Coccaro EF. Identification and regulation of emotions in adults of varying weight statuses. J Health Psychol. 2019 06; 24(7):941-952. PMID: 28810399; PMCID: PMC5882581.
      Citations: 7     Fields:    Translation:Humans
    52. Ammerman BA, Olino TM, Coccaro EF, McCloskey MS. Predicting Nonsuicidal Self-Injury in Borderline Personality Disorder Using Ecological Momentary Assessment. J Pers Disord. 2017 12; 31(6):844-855. PMID: 28072044.
      Citations: 13     Fields:    Translation:Humans
    53. Coccaro EF, Berman ME, McCloskey MS. Development of a screening questionnaire for DSM-5 intermittent explosive disorder (IED-SQ). Compr Psychiatry. 2017 04; 74:21-26. PMID: 28088746.
      Citations: 6     Fields:    Translation:Humans
    54. Coccaro EF, Fanning JR, Fisher E, Couture L, Lee RJ. Social emotional information processing in adults: Development and psychometrics of a computerized video assessment in healthy controls and aggressive individuals. Psychiatry Res. 2017 Feb; 248:40-47. PMID: 28012305; PMCID: PMC6178797.
      Citations: 2     Fields:    Translation:Humans
    55. Coccaro EF, Keedy SK, Gorka SM, King AC, Fanning JR, Lee RJ, Phan KL. Differential fMRI BOLD responses in amygdala in intermittent explosive disorder as a function of past Alcohol Use Disorder. Psychiatry Res Neuroimaging. 2016 Nov 30; 257:5-10. PMID: 27693977; PMCID: PMC6323646.
      Citations: 1     Fields:    Translation:Humans
    56. Coccaro EF, Zagaja C, Chen P, Jacobson K. Relationships between perceived emotional intelligence, aggression, and impulsivity in a population-based adult sample. Psychiatry Res. 2016 Dec 30; 246:255-260. PMID: 27728868.
      Citations: 7     Fields:    Translation:Humans
    57. Coccaro EF, Fanning JR, Keedy SK, Lee RJ. Social cognition in Intermittent Explosive Disorder and aggression. J Psychiatr Res. 2016 12; 83:140-150. PMID: 27621104; PMCID: PMC5744876.
      Citations: 11     Fields:    Translation:Humans
    58. Coccaro EF, Drossos T, Phillipson L. HbA1c levels as a function of emotional regulation and emotional intelligence in patients with type 2 diabetes. Prim Care Diabetes. 2016 10; 10(5):334-41. PMID: 27344533.
      Citations: 12     Fields:    Translation:Humans
    59. Coccaro EF, Fanning J, Lee R. Development of a social emotional information processing assessment for adults (SEIP-Q). Aggress Behav. 2017 Jan; 43(1):47-59. PMID: 27321909; PMCID: PMC6323644.
      Citations: 8     Fields:    Translation:Humans
    60. Coccaro EF, Fridberg DJ, Fanning JR, Grant JE, King AC, Lee R. Substance use disorders: Relationship with intermittent explosive disorder and with aggression, anger, and impulsivity. J Psychiatr Res. 2016 10; 81:127-32. PMID: 27442963; PMCID: PMC5744873.
      Citations: 13     Fields:    Translation:Humans
    61. Fanning JR, Lee R, Coccaro EF. Comorbid intermittent explosive disorder and posttraumatic stress disorder: Clinical correlates and relationship to suicidal behavior. Compr Psychiatry. 2016 10; 70:125-33. PMID: 27624432; PMCID: PMC5024714.
      Citations: 6     Fields:    Translation:Humans
    62. Lee R, Arfanakis K, Evia AM, Fanning J, Keedy S, Coccaro EF. White Matter Integrity Reductions in Intermittent Explosive Disorder. Neuropsychopharmacology. 2016 10; 41(11):2697-703. PMID: 27206265; PMCID: PMC5026737.
      Citations: 9     Fields:    Translation:Humans
    63. Coccaro EF, Lee R, Fanning JR, Fuchs D, Goiny M, Erhardt S, Christensen K, Brundin L, Coussons-Read M. Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects. Psychoneuroendocrinology. 2016 09; 71:189-96. PMID: 27318828; PMCID: PMC5744870.
      Citations: 9     Fields:    Translation:Humans
    64. McCloskey MS, Phan KL, Angstadt M, Fettich KC, Keedy S, Coccaro EF. Amygdala hyperactivation to angry faces in intermittent explosive disorder. J Psychiatr Res. 2016 08; 79:34-41. PMID: 27145325.
      Citations: 29     Fields:    Translation:Humans
    65. Coccaro EF, Lee R, Groer MW, Can A, Coussons-Read M, Postolache TT. Toxoplasma gondii infection: relationship with aggression in psychiatric subjects. J Clin Psychiatry. 2016 Mar; 77(3):334-41. PMID: 27046307.
      Citations: 33     Fields:    Translation:Humans
    66. Puhalla AA, McCloskey MS, Brickman LJ, Fauber R, Coccaro EF. Defense styles in Intermittent Explosive Disorder. Psychiatry Res. 2016 Apr 30; 238:137-142. PMID: 27086223.
      Citations: 1     Fields:    Translation:Humans
    67. Lee RJ, Fanning JR, Coccaro EF. GH response to intravenous clonidine challenge correlates with history of childhood trauma in personality disorder. J Psychiatr Res. 2016 May; 76:38-43. PMID: 26874268.
      Citations: 1     Fields:    Translation:Humans
    68. Coccaro EF, Fitzgerald DA, Lee R, McCloskey M, Phan KL. Frontolimbic Morphometric Abnormalities in Intermittent Explosive Disorder and Aggression. Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 Jan; 1(1):32-38. PMID: 29560894.
      Citations: 14     Fields:    
    69. Fanning JR, Lee R, Gozal D, Coussons-Read M, Coccaro EF. Childhood trauma and parental style: Relationship with markers of inflammation, oxidative stress, and aggression in healthy and personality disordered subjects. Biol Psychol. 2015 Dec; 112:56-65. PMID: 26423894.
      Citations: 21     Fields:    Translation:Humans
    70. Coccaro EF, Lee R, Breen EC, Irwin MR. Inflammatory markers and chronic exposure to fluoxetine, divalproex, and placebo in intermittent explosive disorder. Psychiatry Res. 2015 Oct 30; 229(3):844-9. PMID: 26277033; PMCID: PMC4837655.
      Citations: 7     Fields:    Translation:Humans
    71. Coccaro EF, Lee R, McCloskey M, Csernansky JG, Wang L. Morphometric analysis of amygdla and hippocampus shape in impulsively aggressive and healthy control subjects. J Psychiatr Res. 2015 Oct; 69:80-6. PMID: 26343598; PMCID: PMC5978418.
      Citations: 8     Fields:    Translation:Humans
    72. Coccaro EF. The nature of impulsive aggression: Commentary on "Aggression in borderline personality disorder--A multidimensional model". Personal Disord. 2015 Jul; 6(3):292-3. PMID: 26191823.
      Citations: 1     Fields:    Translation:Humans
    73. Cremers H, Lee R, Keedy S, Phan KL, Coccaro E. Effects of Escitalopram Administration on Face Processing in Intermittent Explosive Disorder: An fMRI Study. Neuropsychopharmacology. 2016 Jan; 41(2):590-7. PMID: 26105140; PMCID: PMC5130134.
      Citations: 9     Fields:    Translation:Humans
    74. Coccaro EF, Fanning JR, Phan KL, Lee R. Serotonin and impulsive aggression. CNS Spectr. 2015 Jun; 20(3):295-302. PMID: 25997605.
      Citations: 39     Fields:    Translation:Humans
    75. Coccaro EF, Lee R, Coussons-Read M. Cerebrospinal fluid inflammatory cytokines and aggression in personality disordered subjects. Int J Neuropsychopharmacol. 2015 Feb 03; 18(7):pyv001. PMID: 25650410; PMCID: PMC4540103.
      Citations: 12     Fields:    Translation:Humans
    76. Fettich KC, McCloskey MS, Look AE, Coccaro EF. Emotion regulation deficits in intermittent explosive disorder. Aggress Behav. 2015 01; 41(1):25-33. PMID: 27539871; PMCID: PMC10264159.
      Citations: 12     Fields:    Translation:Humans
    77. Look AE, McCloskey MS, Coccaro EF. Verbal versus physical aggression in Intermittent Explosive Disorder. Psychiatry Res. 2015 Feb 28; 225(3):531-9. PMID: 25534757; PMCID: PMC4314331.
      Citations: 9     Fields:    Translation:Humans
    78. Coccaro EF, Solis O, Fanning J, Lee R. Emotional intelligence and impulsive aggression in Intermittent Explosive Disorder. J Psychiatr Res. 2015 Feb; 61:135-40. PMID: 25477263; PMCID: PMC4898481.
      Citations: 1     Fields:    Translation:Humans
    79. Fettich KC, McCloskey MS, Look AE, Coccaro EF. Emotion regulation deficits in intermittent explosive disorder. Aggress Behav. 2014 Nov 17. PMID: 25403171.
      Citations:    
    80. Kulper DA, Kleiman EM, McCloskey MS, Berman ME, Coccaro EF. The experience of aggressive outbursts in Intermittent Explosive Disorder. Psychiatry Res. 2015 Feb 28; 225(3):710-5. PMID: 25541537; PMCID: PMC4853646.
      Citations: 12     Fields:    Translation:Humans
    81. Jenkins AL, McCloskey MS, Kulper D, Berman ME, Coccaro EF. Self-harm behavior among individuals with intermittent explosive disorder and personality disorders. J Psychiatr Res. 2015 Jan; 60:125-31. PMID: 25300440.
      Citations: 10     Fields:    Translation:Humans
    82. Coccaro EF, Lee R, Coussons-Read M. Cerebrospinal fluid and plasma C-reactive protein and aggression in personality-disordered subjects: a pilot study. J Neural Transm (Vienna). 2015 Feb; 122(2):321-6. PMID: 25056708; PMCID: PMC4898482.
      Citations: 7     Fields:    Translation:Humans
    83. Lee R, Meyerhoff J, Coccaro EF. Intermittent Explosive Disorder and aversive parental care. Psychiatry Res. 2014 Dec 15; 220(1-2):477-82. PMID: 25064384.
      Citations: 3     Fields:    Translation:Humans
    84. Fanning JR, Meyerhoff JJ, Lee R, Coccaro EF. History of childhood maltreatment in intermittent explosive disorder and suicidal behavior. J Psychiatr Res. 2014 Sep; 56:10-7. PMID: 24935900.
      Citations: 10     Fields:    Translation:Humans
    85. Coccaro EF, Lee R, McCloskey MS. Relationship between psychopathy, aggression, anger, impulsivity, and intermittent explosive disorder. Aggress Behav. 2014 Nov-Dec; 40(6):526-36. PMID: 24760575.
      Citations: 17     Fields:    Translation:Humans
    86. Coccaro EF, Lee R, Coussons-Read M. Elevated plasma inflammatory markers in individuals with intermittent explosive disorder and correlation with aggression in humans. JAMA Psychiatry. 2014 Feb; 71(2):158-65. PMID: 24352431.
      Citations: 59     Fields:    Translation:Humans
    87. Coccaro EF, Lee R, Gozal D. Elevated Plasma Oxidative Stress Markers in Individuals With Intermittent Explosive Disorder and Correlation With Aggression in Humans. Biol Psychiatry. 2016 Jan 15; 79(2):127-35. PMID: 24582164.
      Citations: 17     Fields:    Translation:Humans
    88. Lee RJ, Coccaro EF, Cremers H, McCarron R, Lu SF, Brownstein MJ, Simon NG. A novel V1a receptor antagonist blocks vasopressin-induced changes in the CNS response to emotional stimuli: an fMRI study. Front Syst Neurosci. 2013; 7:100. PMID: 24376401; PMCID: PMC3859978.
      Citations: 22     
    89. Coccaro EF, Lee R, McCloskey MS. Validity of the new A1 and A2 criteria for DSM-5 intermittent explosive disorder. Compr Psychiatry. 2014 Feb; 55(2):260-7. PMID: 24321204.
      Citations: 11     Fields:    Translation:Humans
    90. Barry TD, Marcus DK, Barry CT, Coccaro EF. The latent structure of oppositional defiant disorder in children and adults. J Psychiatr Res. 2013 Dec; 47(12):1932-9. PMID: 24075326; PMCID: PMC3825265.
      Citations: 9     Fields:    Translation:Humans
    91. Coccaro EF, Lee R, Vezina P. Cerebrospinal fluid glutamate concentration correlates with impulsive aggression in human subjects. J Psychiatr Res. 2013 Sep; 47(9):1247-53. PMID: 23791397; PMCID: PMC3980459.
      Citations: 22     Fields:    Translation:Humans
    92. Coccaro EF. What is the nature of serotonergic abnormalities in human aggression? Biol Psychiatry. 2012 Dec 15; 72(12):980-1. PMID: 23153521.
      Citations: 3     Fields:    Translation:HumansCells
    93. Phan KL, Coccaro EF, Angstadt M, Kreger KJ, Mayberg HS, Liberzon I, Stein MB. Corticolimbic brain reactivity to social signals of threat before and after sertraline treatment in generalized social phobia. Biol Psychiatry. 2013 Feb 15; 73(4):329-36. PMID: 23164370; PMCID: PMC3557668.
      Citations: 52     Fields:    Translation:Humans
    94. Coccaro EF, Lee R, Liu T, Mathé AA. Cerebrospinal fluid neuropeptide Y-like immunoreactivity correlates with impulsive aggression in human subjects. Biol Psychiatry. 2012 Dec 15; 72(12):997-1003. PMID: 22985695.
      Citations: 12     Fields:    Translation:Humans
    95. Chen EY, Fettich KC, Tierney M, Cummings H, Berona J, Weissman J, Ward A, Christensen K, Southward M, Gordon KH, Mitchell J, Coccaro E. Factors associated with suicide ideation in severely obese bariatric surgery-seeking individuals. Suicide Life Threat Behav. 2012 Oct; 42(5):541-9. PMID: 22957662; PMCID: PMC5670739.
      Citations: 6     Fields:    Translation:Humans
    96. Kuna ST, Maislin G, Pack FM, Staley B, Hachadoorian R, Coccaro EF, Pack AI. Heritability of performance deficit accumulation during acute sleep deprivation in twins. Sleep. 2012 Sep 01; 35(9):1223-33. PMID: 22942500; PMCID: PMC3413799.
      Citations: 55     Fields:    Translation:Humans
    97. Coccaro EF. Intermittent explosive disorder as a disorder of impulsive aggression for DSM-5. Am J Psychiatry. 2012 Jun; 169(6):577-88. PMID: 22535310.
      Citations: 47     Fields:    Translation:Humans
    98. Lee RJ, Gill A, Chen B, McCloskey M, Coccaro EF. Modulation of central serotonin affects emotional information processing in impulsive aggressive personality disorder. J Clin Psychopharmacol. 2012 Jun; 32(3):329-35. PMID: 22544009.
      Citations: 4     Fields:    Translation:Humans
    99. Coccaro EF, Nayyer H, McCloskey MS. Personality disorder--not otherwise specified evidence of validity and consideration for DSM-5. Compr Psychiatry. 2012 Oct; 53(7):907-14. PMID: 22520088.
      Citations: 17     Fields:    Translation:Humans
    100. Coccaro EF, Boparai A, Lee R. Cerebrospinal fluid 5-hydroxyindolacetic acid correlates directly with negative affective intensity, but not affective lability, in human subjects. Int J Neuropsychopharmacol. 2013 Mar; 16(2):261-9. PMID: 22475556.
      Citations: 1     Fields:    Translation:Humans
    101. Marcus DK, Norris AL, Coccaro EF. The latent structure of attention deficit/hyperactivity disorder in an adult sample. J Psychiatr Res. 2012 Jun; 46(6):782-9. PMID: 22480749; PMCID: PMC3359405.
      Citations: 11     Fields:    Translation:Humans
    102. Coccaro EF, Lee R, Owens MJ, Kinkead B, Nemeroff CB. Cerebrospinal fluid substance P-like immunoreactivity correlates with aggression in personality disordered subjects. Biol Psychiatry. 2012 Aug 01; 72(3):238-43. PMID: 22449753.
      Citations: 7     Fields:    Translation:Humans
    103. Chen P, Coccaro EF, Jacobson KC. Hostile attributional bias, negative emotional responding, and aggression in adults: moderating effects of gender and impulsivity. Aggress Behav. 2012 Jan-Feb; 38(1):47-63. PMID: 24833604; PMCID: PMC4243523.
      Citations: 16     Fields:    Translation:Humans
    104. Coccaro EF, Schmidt-Kaplan CA. Life history of impulsive behavior: development and validation of a new questionnaire. J Psychiatr Res. 2012 Mar; 46(3):346-52. PMID: 22212770.
      Citations: 15     Fields:    Translation:Humans
    105. Chen P, Coccaro EF, Lee R, Jacobson KC. Moderating effects of childhood maltreatment on associations between social information processing and adult aggression. Psychol Med. 2012 Jun; 42(6):1293-304. PMID: 22008562; PMCID: PMC4255557.
      Citations: 9     Fields:    Translation:Humans
    106. Marseille R, Lee R, Coccaro EF. Inter-relationship between different platelet measures of 5-HT and their relationship to aggression in human subjects. Prog Neuropsychopharmacol Biol Psychiatry. 2012 Mar 30; 36(2):277-81. PMID: 22019855.
      Citations: 3     Fields:    Translation:HumansCells
    107. Dakwar E, Popii M, Coccaro EF. Lifetime history of cigarette smoking associated with aggression and impulsivity in both healthy and personality disordered volunteers. J Pers Disord. 2011 Oct; 25(5):645-55. PMID: 22023301; PMCID: PMC3594993.
      Citations: 8     Fields:    Translation:Humans
    108. Phan KL, Lee R, Coccaro EF. Personality predictors of antiaggressive response to fluoxetine: inverse association with neuroticism and harm avoidance. Int Clin Psychopharmacol. 2011 Sep; 26(5):278-83. PMID: 21795983.
      Citations: 2     Fields:    Translation:Humans
    109. Vu TH, Coccaro EF, Eichler EE, Girirajan S. Genomic architecture of aggression: rare copy number variants in intermittent explosive disorder. Am J Med Genet B Neuropsychiatr Genet. 2011 Dec; 156B(7):808-16. PMID: 21812102; PMCID: PMC3168586.
      Citations: 8     Fields:    Translation:Humans
    110. Coccaro EF, Ong AD, Seroczynski AD, Bergeman CS. Affective intensity and lability: heritability in adult male twins. J Affect Disord. 2012 Feb; 136(3):1011-6. PMID: 21788082.
      Citations: 9     Fields:    Translation:Humans
    111. Vaccarino AL, Anderson KE, Borowsky B, Coccaro E, Craufurd D, Endicott J, Giuliano J, Groves M, Guttman M, Ho AK, Kupchak P, Paulsen JS, Stanford MS, van Kammen DP, Watson D, Wu KD, Evans K. Assessing behavioural manifestations prior to clinical diagnosis of huntington disease: "anger and irritability" and "obsessions and compulsions". PLoS Curr. 2011 Jul 11; 3:RRN1241. PMID: 21826116; PMCID: PMC3122583.
      Citations: 6     
    112. Coccaro EF, Sripada CS, Yanowitch RN, Phan KL. Corticolimbic function in impulsive aggressive behavior. Biol Psychiatry. 2011 Jun 15; 69(12):1153-9. PMID: 21531387.
      Citations: 79     Fields:    Translation:HumansAnimals
    113. Yanowitch R, Coccaro EF. The neurochemistry of human aggression. Adv Genet. 2011; 75:151-69. PMID: 22078480.
      Citations: 36     Fields:    Translation:HumansCells
    114. Bevilacqua L, Kaprio J, Yuan Q, Tikkanen R, Paunio T, Zhou Z, Wedenoja J, Maroteaux L, Diaz S, Belmer A, Hodgkinson CA, Dell'osso L, Suvisaari J, Coccaro E, Rose RJ, Peltonen L, Virkkunen M, Goldman D, Doly S. A population-specific HTR2B stop codon predisposes to severe impulsivity. Nature. 2010 Dec 23; 468(7327):1061-6. PMID: 21179162; PMCID: PMC3183507.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    115. Lee R, Chong B, Coccaro E. Growth hormone responses to GABAB receptor challenge with baclofen and impulsivity in healthy control and personality disorder subjects. Psychopharmacology (Berl). 2011 May; 215(1):41-8. PMID: 21181128.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    116. Gollan JK, McCloskey M, Hoxha D, Coccaro EF. How do depressed and healthy adults interpret nuanced facial expressions? J Abnorm Psychol. 2010 Nov; 119(4):804-10. PMID: 20939654; PMCID: PMC3805828.
      Citations: 29     Fields:    Translation:Humans
    117. Lee R, Coccaro EF. Plasma homovanillic acid correlates inversely with history of childhood trauma in personality disordered and healthy control adults. J Neural Transm (Vienna). 2010 Nov; 117(11):1327-34. PMID: 20953642.
      Citations: 1     Fields:    Translation:Humans
    118. Chen EY, McCloskey MS, Michelson S, Gordon KH, Coccaro E. Characterizing eating disorders in a personality disorders sample. Psychiatry Res. 2011 Feb 28; 185(3):427-32. PMID: 20667417; PMCID: PMC2972373.
      Citations: 3     Fields:    Translation:Humans
    119. Coccaro EF. Intermittent explosive disorder: development of integrated research criteria for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Compr Psychiatry. 2011 Mar-Apr; 52(2):119-25. PMID: 21295216.
      Citations: 20     Fields:    Translation:Humans
    120. Coccaro EF. A family history study of intermittent explosive disorder. J Psychiatr Res. 2010 Nov; 44(15):1101-5. PMID: 20488459.
      Citations: 6     Fields:    Translation:Humans
    121. Coccaro EF, Kavoussi RJ. GH response to intravenous clonidine challenge: absence of relationship with behavioral irritability, aggression, or impulsivity in human subjects. Psychiatry Res. 2010 Jul 30; 178(2):443-5. PMID: 20483477.
      Citations: 1     Fields:    Translation:Humans
    122. McCloskey MS, Kleabir K, Berman ME, Chen EY, Coccaro EF. Unhealthy aggression: intermittent explosive disorder and adverse physical health outcomes. Health Psychol. 2010 May; 29(3):324-32. PMID: 20496987.
      Citations: 17     Fields:    Translation:Humans
    123. Yeh MT, Coccaro EF, Jacobson KC. Multivariate behavior genetic analyses of aggressive behavior subtypes. Behav Genet. 2010 Sep; 40(5):603-17. PMID: 20432061; PMCID: PMC3267542.
      Citations: 15     Fields:    Translation:Humans
    124. Almeida M, Lee R, Coccaro EF. Cortisol responses to ipsapirone challenge correlate with aggression, while basal cortisol levels correlate with impulsivity, in personality disorder and healthy volunteer subjects. J Psychiatr Res. 2010 Oct; 44(14):874-80. PMID: 20378126.
      Citations: 4     Fields:    Translation:HumansCells
    125. Coccaro EF, Lee R. Cerebrospinal fluid 5-hydroxyindolacetic acid and homovanillic acid: reciprocal relationships with impulsive aggression in human subjects. J Neural Transm (Vienna). 2010 Feb; 117(2):241-8. PMID: 20069438.
      Citations: 16     Fields:    Translation:Humans
    126. Coccaro EF, Lee R, Kavoussi RJ. Aggression, suicidality, and intermittent explosive disorder: serotonergic correlates in personality disorder and healthy control subjects. Neuropsychopharmacology. 2010 Jan; 35(2):435-44. PMID: 19776731; PMCID: PMC3055394.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    127. Ruocco AC, McCloskey MS, Lee R, Coccaro EF. Indices of orbitofrontal and prefrontal function in Cluster B and Cluster C personality disorders. Psychiatry Res. 2009 Dec 30; 170(2-3):282-5. PMID: 19900716; PMCID: PMC2796539.
      Citations: 1     Fields:    Translation:Humans
    128. Murray-Close D, Ostrov JM, Nelson DA, Crick NR, Coccaro EF. Proactive, reactive, and romantic relational aggression in adulthood: measurement, predictive validity, gender differences, and association with Intermittent Explosive Disorder. J Psychiatr Res. 2010 Apr; 44(6):393-404. PMID: 19822329; PMCID: PMC2849926.
      Citations: 26     Fields:    Translation:Humans
    129. Coccaro EF, Lee R, Kavoussi RJ. Inverse relationship between numbers of 5-HT transporter binding sites and life history of aggression and intermittent explosive disorder. J Psychiatr Res. 2010 Feb; 44(3):137-42. PMID: 19767013.
      Citations: 8     Fields:    Translation:HumansCells
    130. Lee R, Ferris C, Van de Kar LD, Coccaro EF. Cerebrospinal fluid oxytocin, life history of aggression, and personality disorder. Psychoneuroendocrinology. 2009 Nov; 34(10):1567-73. PMID: 19577376.
      Citations: 35     Fields:    Translation:Humans
    131. Ferguson SD, Coccaro EF. History of mild to moderate traumatic brain injury and aggression in physically healthy participants with and without personality disorder. J Pers Disord. 2009 Jun; 23(3):230-9. PMID: 19538079.
      Citations: 2     Fields:    Translation:Humans
    132. Berman ME, McCloskey MS, Fanning JR, Schumacher JA, Coccaro EF. Serotonin augmentation reduces response to attack in aggressive individuals. Psychol Sci. 2009 Jun; 20(6):714-20. PMID: 19422623; PMCID: PMC2728471.
      Citations: 16     Fields:    Translation:Humans
    133. Coccaro EF, Lee RJ, Kavoussi RJ. A double-blind, randomized, placebo-controlled trial of fluoxetine in patients with intermittent explosive disorder. J Clin Psychiatry. 2009 Apr 21; 70(5):653-62. PMID: 19389333.
      Citations: 44     Fields:    Translation:Humans
    134. Phan KL, Orlichenko A, Boyd E, Angstadt M, Coccaro EF, Liberzon I, Arfanakis K. Preliminary evidence of white matter abnormality in the uncinate fasciculus in generalized social anxiety disorder. Biol Psychiatry. 2009 Oct 01; 66(7):691-4. PMID: 19362707; PMCID: PMC2743779.
      Citations: 107     Fields:    Translation:HumansCells
    135. Coccaro EF, Noblett KL, McCloskey MS. Attributional and emotional responses to socially ambiguous cues: validation of a new assessment of social/emotional information processing in healthy adults and impulsive aggressive patients. J Psychiatr Res. 2009 Jul; 43(10):915-25. PMID: 19345371.
      Citations: 30     Fields:    Translation:Humans
    136. McCloskey MS, New AS, Siever LJ, Goodman M, Koenigsberg HW, Flory JD, Coccaro EF. Evaluation of behavioral impulsivity and aggression tasks as endophenotypes for borderline personality disorder. J Psychiatr Res. 2009 Aug; 43(12):1036-48. PMID: 19232640; PMCID: PMC2853811.
      Citations: 43     Fields:    Translation:Humans
    137. McCloskey MS, Berman ME, Echevarria DJ, Coccaro EF. Effects of acute alcohol intoxication and paroxetine on aggression in men. Alcohol Clin Exp Res. 2009 Apr; 33(4):581-90. PMID: 19183141.
      Citations: 9     Fields:    Translation:Humans
    138. Lee R, Kavoussi RJ, Coccaro EF. Placebo-controlled, randomized trial of fluoxetine in the treatment of aggression in male intimate partner abusers. Int Clin Psychopharmacol. 2008 Nov; 23(6):337-41. PMID: 18854722.
      Citations: 5     Fields:    Translation:Humans
    139. McCloskey MS, Ben-Zeev D, Lee R, Berman ME, Coccaro EF. Acute tryptophan depletion and self-injurious behavior in aggressive patients and healthy volunteers. Psychopharmacology (Berl). 2009 Mar; 203(1):53-61. PMID: 18946662.
      Citations: 18     Fields:    Translation:Humans
    140. McCloskey MS, Noblett KL, Deffenbacher JL, Gollan JK, Coccaro EF. Cognitive-behavioral therapy for intermittent explosive disorder: a pilot randomized clinical trial. J Consult Clin Psychol. 2008 Oct; 76(5):876-86. PMID: 18837604.
      Citations: 20     Fields:    Translation:Humans
    141. Kumar RA, McGhee KA, Leach S, Bonaguro R, Maclean A, Aguirre-Hernandez R, Abrahams BS, Coccaro EF, Hodgins S, Turecki G, Condon A, Muir WJ, Brooks-Wilson AR, Blackwood DH, Simpson EM. Initial association of NR2E1 with bipolar disorder and identification of candidate mutations in bipolar disorder, schizophrenia, and aggression through resequencing. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 05; 147B(6):880-9. PMID: 18205168.
      Citations: 16     Fields:    Translation:HumansCells
    142. Pitroda S, Angstadt M, McCloskey MS, Coccaro EF, Phan KL. Emotional experience modulates brain activity during fixation periods between tasks. Neurosci Lett. 2008 Oct 03; 443(2):72-6. PMID: 18674589; PMCID: PMC2558674.
      Citations: 3     Fields:    Translation:Humans
    143. Lee R, Petty F, Coccaro EF. Cerebrospinal fluid GABA concentration: relationship with impulsivity and history of suicidal behavior, but not aggression, in human subjects. J Psychiatr Res. 2009 Jan; 43(4):353-9. PMID: 18490031.
      Citations: 13     Fields:    Translation:Humans
    144. Gollan JK, Pane HT, McCloskey MS, Coccaro EF. Identifying differences in biased affective information processing in major depression. Psychiatry Res. 2008 May 30; 159(1-2):18-24. PMID: 18342954; PMCID: PMC2571942.
      Citations: 64     Fields:    Translation:Humans
    145. McCloskey MS, Ben-Zeev D, Lee R, Coccaro EF. Prevalence of suicidal and self-injurious behavior among subjects with intermittent explosive disorder. Psychiatry Res. 2008 Mar 15; 158(2):248-50. PMID: 18221794; PMCID: PMC2291349.
      Citations: 9     Fields:    Translation:Humans
    146. McCloskey MS, Lee R, Berman ME, Noblett KL, Coccaro EF. The relationship between impulsive verbal aggression and intermittent explosive disorder. Aggress Behav. 2008 Jan-Feb; 34(1):51-60. PMID: 17654692.
      Citations: 12     Fields:    Translation:Humans
    147. Coccaro EF, Beresford B, Minar P, Kaskow J, Geracioti T. CSF testosterone: relationship to aggression, impulsivity, and venturesomeness in adult males with personality disorder. J Psychiatr Res. 2007 Sep; 41(6):488-92. PMID: 16765987.
      Citations: 9     Fields:    Translation:Humans
    148. Jensen PS, Youngstrom EA, Steiner H, Findling RL, Meyer RE, Malone RP, Carlson GA, Coccaro EF, Aman MG, Blair J, Dougherty D, Ferris C, Flynn L, Green E, Hoagwood K, Hutchinson J, Laughren T, Leve LD, Novins DK, Vitiello B. Consensus report on impulsive aggression as a symptom across diagnostic categories in child psychiatry: implications for medication studies. J Am Acad Child Adolesc Psychiatry. 2007 Mar; 46(3):309-322. PMID: 17314717.
      Citations: 50     Fields:    Translation:Humans
    149. Coccaro EF, McCloskey MS, Fitzgerald DA, Phan KL. Amygdala and orbitofrontal reactivity to social threat in individuals with impulsive aggression. Biol Psychiatry. 2007 Jul 15; 62(2):168-78. PMID: 17210136.
      Citations: 195     Fields:    Translation:Humans
    150. Coccaro EF, Jacobson KC. PennTwins: a population-based cohort for twin studies. Twin Res Hum Genet. 2006 Dec; 9(6):998-1005. PMID: 17254443; PMCID: PMC4248574.
      Citations: 8     Fields:    Translation:Humans
    151. Coccaro EF, Hirsch SL, Stein MA. Plasma homovanillic acid correlates inversely with history of learning problems in healthy volunteer and personality disordered subjects. Psychiatry Res. 2007 Jan 15; 149(1-3):297-302. PMID: 17113158.
      Citations: 6     Fields:    Translation:Humans
    152. Lee RJ, Gollan J, Kasckow J, Geracioti T, Coccaro EF. CSF corticotropin-releasing factor in personality disorder: relationship with self-reported parental care. Neuropsychopharmacology. 2006 Oct; 31(10):2289-95. PMID: 16880775.
      Citations: 10     Fields:    Translation:Humans
    153. Kessler RC, Coccaro EF, Fava M, Jaeger S, Jin R, Walters E. The prevalence and correlates of DSM-IV intermittent explosive disorder in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2006 Jun; 63(6):669-78. PMID: 16754840; PMCID: PMC1924721.
      Citations: 92     Fields:    Translation:Humans
    154. Minzenberg MJ, Grossman R, New AS, Mitropoulou V, Yehuda R, Goodman M, Reynolds DA, Silverman JM, Coccaro EF, Marcus S, Siever LJ. Blunted hormone responses to Ipsapirone are associated with trait impulsivity in personality disorder patients. Neuropsychopharmacology. 2006 Jan; 31(1):197-203. PMID: 16123761.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    155. Coccaro EF, Posternak MA, Zimmerman M. Prevalence and features of intermittent explosive disorder in a clinical setting. J Clin Psychiatry. 2005 Oct; 66(10):1221-7. PMID: 16259534.
      Citations: 18     Fields:    Translation:Humans
    156. McCloskey MS, Berman ME, Noblett KL, Coccaro EF. Intermittent explosive disorder-integrated research diagnostic criteria: convergent and discriminant validity. J Psychiatr Res. 2006 Apr; 40(3):231-42. PMID: 16153657.
      Citations: 19     Fields:    Translation:Humans
    157. Coccaro EF. Association of C-reactive protein elevation with trait aggression and hostility in personality disordered subjects: a pilot study. J Psychiatr Res. 2006 Aug; 40(5):460-5. PMID: 15993896.
      Citations: 29     Fields:    Translation:Humans
    158. Lee R, Geracioti TD, Kasckow JW, Coccaro EF. Childhood trauma and personality disorder: positive correlation with adult CSF corticotropin-releasing factor concentrations. Am J Psychiatry. 2005 May; 162(5):995-7. PMID: 15863804.
      Citations: 28     Fields:    Translation:Humans
    159. Noblett KL, Coccaro EF. Molecular genetics of personality. Curr Psychiatry Rep. 2005 Mar; 7(1):73-80. PMID: 15717990.
      Citations: 4     Fields:    Translation:Humans
    160. Hollander E, Swann AC, Coccaro EF, Jiang P, Smith TB. Impact of trait impulsivity and state aggression on divalproex versus placebo response in borderline personality disorder. Am J Psychiatry. 2005 Mar; 162(3):621-4. PMID: 15741486.
      Citations: 30     Fields:    Translation:HumansCTClinical Trials
    161. Coccaro EF. Striatal Amphetamine-induced Dopamine Release in Schizotypal Personality Disorder. Curr Psychiatry Rep. 2005 Mar; 7(1):40. PMID: 15717985.
      Citations:    Fields:    
    162. Coccaro EF. Memories of childhood abuse in borderline personality disorder. Curr Psychiatry Rep. 2005 Mar; 7(1):39. PMID: 15717984.
      Citations:    Fields:    
    163. McCloskey MS, Phan KL, Coccaro EF. Neuroimaging and personality disorders. Curr Psychiatry Rep. 2005 Mar; 7(1):65-72. PMID: 15717989.
      Citations: 14     Fields:    Translation:Humans
    164. Gollan JK, Lee R, Coccaro EF. Developmental psychopathology and neurobiology of aggression. Dev Psychopathol. 2005; 17(4):1151-71. PMID: 16613435.
      Citations: 12     Translation:Humans
    165. Bunce SC, Noblett KL, McCloskey MS, Coccaro EF. High prevalence of personality disorders among healthy volunteers for research: implications for control group bias. J Psychiatr Res. 2005 Jul; 39(4):421-30. PMID: 15804393.
      Citations: 11     Fields:    Translation:Humans
    166. Coccaro EF, Schmidt CA, Samuels JF, Nestadt G. Lifetime and 1-month prevalence rates of intermittent explosive disorder in a community sample. J Clin Psychiatry. 2004 Jun; 65(6):820-4. PMID: 15291659.
      Citations: 25     Fields:    Translation:Humans
    167. Schmidt CA, Fallon AE, Coccaro EF. Assessment of behavioral and cognitive impulsivity: development and validation of the Lifetime History of Impulsive Behaviors Interview. Psychiatry Res. 2004 Apr 30; 126(2):107-21. PMID: 15123390.
      Citations: 6     Fields:    Translation:Humans
    168. Goveas JS, Csernansky JG, Coccaro EF. Platelet serotonin content correlates inversely with life history of aggression in personality-disordered subjects. Psychiatry Res. 2004 Apr 15; 126(1):23-32. PMID: 15081624.
      Citations: 8     Fields:    Translation:Humans
    169. Coccaro EF. Borderline personality disorder therapy with omega-3 fatty acids. Curr Psychiatry Rep. 2004 Feb; 6(1):42. PMID: 14738704.
      Citations:    Fields:    
    170. Coccaro EF. Intermittent explosive disorder and impulsive aggression: the time for serious study is now. Curr Psychiatry Rep. 2004 Feb; 6(1):1-2. PMID: 14738696.
      Citations: 1     Fields:    Translation:Humans
    171. Coccaro EF. Divalproex for cluster B personality disorders. Curr Psychiatry Rep. 2004 Feb; 6(1):41. PMID: 14738703.
      Citations:    Fields:    
    172. Coccaro EF, Lee R, McCloskey M. Norepinephrine function in personality disorder: plasma free MHPG correlates inversely with life history of aggression. CNS Spectr. 2003 Oct; 8(10):731-6. PMID: 14712171.
      Citations: 7     Fields:    Translation:Humans
    173. Lee R, Garcia F, van de Kar LD, Hauger RD, Coccaro EF. Plasma oxytocin in response to pharmaco-challenge to D-fenfluramine and placebo in healthy men. Psychiatry Res. 2003 May 30; 118(2):129-36. PMID: 12798977.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    174. Hollander E, Tracy KA, Swann AC, Coccaro EF, McElroy SL, Wozniak P, Sommerville KW, Nemeroff CB. Divalproex in the treatment of impulsive aggression: efficacy in cluster B personality disorders. Neuropsychopharmacology. 2003 Jun; 28(6):1186-97. PMID: 12700713.
      Citations: 41     Fields:    Translation:HumansCTClinical Trials
    175. Endicott J, Tracy K, Burt D, Olson E, Coccaro EF. A novel approach to assess inter-rater reliability in the use of the Overt Aggression Scale-Modified. Psychiatry Res. 2002 Oct 10; 112(2):153-9. PMID: 12429361.
      Citations: 5     Fields:    Translation:Humans
    176. Best M, Williams JM, Coccaro EF. Evidence for a dysfunctional prefrontal circuit in patients with an impulsive aggressive disorder. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8448-53. PMID: 12034876; PMCID: PMC123087.
      Citations: 74     Fields:    Translation:Humans
    177. Lee R, Coccaro E. The neuropsychopharmacology of criminality and aggression. Can J Psychiatry. 2001 Feb; 46(1):35-44. PMID: 11221488.
      Citations: 6     Fields:    Translation:Humans
    178. Reist C, Vu R, Coccaro EF, Fujimoto K. Serotonin-stimulated calcium release is decreased in platelets from high impulsivity patients. Int J Neuropsychopharmacol. 2000 Dec; 3(4):315-320. PMID: 11343610.
      Citations:    Fields:    
    179. Coccaro EF. Is the nature of personality disorder categoric or dimensional? Curr Psychiatry Rep. 2000 Feb; 2(1):49-50. PMID: 11122931.
      Citations:    Fields:    Translation:Humans
    180. Coccaro EF. Intermittent explosive disorder. Curr Psychiatry Rep. 2000 Feb; 2(1):67-71. PMID: 11122935.
      Citations: 14     Fields:    Translation:Humans
    181. Coccaro EF, Blanchette PL. Education in geriatrics and gerontology. N Engl J Med. 1979 Jun 14; 300(24):1399. PMID: 440387.
      Citations:    Fields:    
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