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Connection

Alan Sanders to Genetic Predisposition to Disease

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This is a "connection" page, showing publications Alan Sanders has written about Genetic Predisposition to Disease.
Alan Sanders
Connection Strength
1.400
Genetic Predisposition to Disease
  1. PICALM Alzheimer's risk allele causes aberrant lipid droplets in microglia. Nature. 2025 Oct; 646(8087):1178-1186.
    View in: PubMed
    Score: 0.122
  2. Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci. Cell Stem Cell. 2017 09 07; 21(3):305-318.e8.
    View in: PubMed
    Score: 0.070
  3. Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data. PLoS Genet. 2016 Dec; 12(12):e1006493.
    View in: PubMed
    Score: 0.067
  4. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2015 Oct; 11(10):e1005378.
    View in: PubMed
    Score: 0.061
  5. Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants. Hum Mol Genet. 2015 Aug 15; 24(16):4674-85.
    View in: PubMed
    Score: 0.060
  6. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet. 2013 Oct; 45(10):1150-9.
    View in: PubMed
    Score: 0.053
  7. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013 Sep; 45(9):984-94.
    View in: PubMed
    Score: 0.053
  8. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 2013 May; 45(5):501-12.
    View in: PubMed
    Score: 0.052
  9. Genome-wide association study of multiplex schizophrenia pedigrees. Am J Psychiatry. 2012 Sep; 169(9):963-73.
    View in: PubMed
    Score: 0.050
  10. Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain. Mol Psychiatry. 2012 Feb; 17(2):193-201.
    View in: PubMed
    Score: 0.045
  11. Genome-wide association study of recurrent early-onset major depressive disorder. Mol Psychiatry. 2011 Feb; 16(2):193-201.
    View in: PubMed
    Score: 0.042
  12. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature. 2009 Aug 06; 460(7256):753-7.
    View in: PubMed
    Score: 0.040
  13. Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms. Mol Psychiatry. 2009 Aug; 14(8):786-95.
    View in: PubMed
    Score: 0.039
  14. Meta-analysis of 32 genome-wide linkage studies of schizophrenia. Mol Psychiatry. 2009 Aug; 14(8):774-85.
    View in: PubMed
    Score: 0.039
  15. Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2. Mol Psychiatry. 2009 Jan; 14(1):30-6.
    View in: PubMed
    Score: 0.038
  16. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet. 2008 Sep; 40(9):1053-5.
    View in: PubMed
    Score: 0.038
  17. No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics. Am J Psychiatry. 2008 Apr; 165(4):497-506.
    View in: PubMed
    Score: 0.036
  18. DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene. Hum Hered. 2007; 64(2):97-106.
    View in: PubMed
    Score: 0.034
  19. Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample. Am J Hum Genet. 2006 Feb; 78(2):315-33.
    View in: PubMed
    Score: 0.031
  20. Polygenic Score Complements Family History and Lynch Syndrome Genes for Predicting Colorectal Cancer Risk. JCO Precis Oncol. 2025 Jul; 9:e2500081.
    View in: PubMed
    Score: 0.030
  21. Estimating Cancer Penetrance in Carriers of BRCA2 Pathogenic Variants Using Cancer-Specific Polygenic Scores. Cancer Med. 2025 Jun; 14(11):e70990.
    View in: PubMed
    Score: 0.030
  22. Complexities in psychiatric genetics. Int Rev Psychiatry. 2004 Nov; 16(4):284-93.
    View in: PubMed
    Score: 0.029
  23. Scaled and efficient derivation of loss-of-function alleles in risk genes for neurodevelopmental and psychiatric disorders in human iPSCs. Stem Cell Reports. 2024 10 08; 19(10):1489-1504.
    View in: PubMed
    Score: 0.029
  24. Validation of GenProb-T1D and its clinical utility for differentiating types of diabetes in a biobank from a US healthcare system. J Diabetes Investig. 2025 Jan; 16(1):10-15.
    View in: PubMed
    Score: 0.028
  25. GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors. Am J Psychiatry. 2023 10 01; 180(10):723-738.
    View in: PubMed
    Score: 0.027
  26. No major schizophrenia locus detected on chromosome 1q in a large multicenter sample. Science. 2002 Apr 26; 296(5568):739-41.
    View in: PubMed
    Score: 0.024
  27. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature. 2022 04; 604(7906):502-508.
    View in: PubMed
    Score: 0.024
  28. Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biol Psychiatry. 2022 01 01; 91(1):102-117.
    View in: PubMed
    Score: 0.022
  29. Follow-up study on a susceptibility locus for schizophrenia on chromosome 6q. Am J Med Genet. 1999 Aug 20; 88(4):337-43.
    View in: PubMed
    Score: 0.020
  30. Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts. Biol Psychiatry. 2019 06 15; 85(12):1065-1073.
    View in: PubMed
    Score: 0.020
  31. Images in neuroscience. Clinical Genetics, VIII. From genetics to pathophysiology--candidate genes. Am J Psychiatry. 1998 Feb; 155(2):162.
    View in: PubMed
    Score: 0.018
  32. Images in neuroscience. Clinical genetics, VII. From genetics to pathophysiology: positional cloning. Am J Psychiatry. 1998 Jan; 155(1):3.
    View in: PubMed
    Score: 0.018
  33. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nat Genet. 2017 01; 49(1):27-35.
    View in: PubMed
    Score: 0.017
  34. New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. Int J Epidemiol. 2015 Oct; 44(5):1706-21.
    View in: PubMed
    Score: 0.015
  35. A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder. Am J Hum Genet. 2014 Dec 04; 95(6):744-53.
    View in: PubMed
    Score: 0.014
  36. Implication of a rare deletion at distal 16p11.2 in schizophrenia. JAMA Psychiatry. 2013 Mar; 70(3):253-60.
    View in: PubMed
    Score: 0.013
  37. Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Arch Gen Psychiatry. 2012 Aug; 69(8):854-60.
    View in: PubMed
    Score: 0.012
  38. Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. Am J Psychiatry. 2011 Mar; 168(3):302-16.
    View in: PubMed
    Score: 0.011
  39. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet. 2010 Nov; 42(11):937-48.
    View in: PubMed
    Score: 0.011
  40. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 2010 Oct 14; 467(7317):832-8.
    View in: PubMed
    Score: 0.011
  41. Multicenter linkage study of schizophrenia loci on chromosome 22q. Mol Psychiatry. 2004 Aug; 9(8):784-95.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.