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Connection

Joseph Piccirilli to Oligonucleotides

This is a "connection" page, showing publications Joseph Piccirilli has written about Oligonucleotides.
Connection Strength

1.851
  1. Automated solid-phase synthesis of RNA oligonucleotides containing a nonbridging phosphorodithioate linkage via phosphorothioamidites. J Org Chem. 2012 Nov 02; 77(21):9889-92.
    View in: PubMed
    Score: 0.368
  2. Efficient chemical synthesis of AppDNA by adenylation of immobilized DNA-5'-monophosphate. Org Lett. 2009 Mar 05; 11(5):1067-70.
    View in: PubMed
    Score: 0.286
  3. Efficient synthesis of [2'-18O]uridine and its incorporation into oligonucleotides: a new tool for mechanistic study of nucleotidyl transfer reactions by isotope effect analysis. J Org Chem. 2008 Jan 04; 73(1):309-11.
    View in: PubMed
    Score: 0.262
  4. Synthesis of 2'-C-difluoromethylribonucleosides and their enzymatic incorporation into oligonucleotides. J Org Chem. 2005 Sep 30; 70(20):7902-10.
    View in: PubMed
    Score: 0.225
  5. The tetrahymena ribozyme cleaves a 5'-methylene phosphonate monoester approximately 10(2)-fold faster than a normal phosphate diester: implications for enzyme catalysis of phosphoryl transfer reactions. Biochemistry. 2001 Sep 18; 40(37):10911-26.
    View in: PubMed
    Score: 0.170
  6. Evidence That Nucleophile Deprotonation Exceeds Bond Formation in the HDV Ribozyme Transition State. Biochemistry. 2018 06 26; 57(25):3465-3472.
    View in: PubMed
    Score: 0.135
  7. Synthesis of 2'-O-photocaged ribonucleoside phosphoramidites. Nucleosides Nucleotides Nucleic Acids. 2015; 34(2):114-29.
    View in: PubMed
    Score: 0.107
  8. The mechanism of RNA strand scission: an experimental measure of the Brønsted coefficient, beta nuc. Angew Chem Int Ed Engl. 2007; 46(20):3714-7.
    View in: PubMed
    Score: 0.061
  9. A systematic, ligation-based approach to study RNA modifications. RNA. 2006 Nov; 12(11):2025-33.
    View in: PubMed
    Score: 0.060
  10. Improved synthesis of 2'-amino-2'-deoxyguanosine and its phosphoramidite. Bioorg Med Chem. 2006 Feb 01; 14(3):705-13.
    View in: PubMed
    Score: 0.056
  11. Branched kissing loops for the construction of diverse RNA homooligomeric nanostructures. Nat Chem. 2020 03; 12(3):249-259.
    View in: PubMed
    Score: 0.038
  12. Redesigning nucleic acids. Pure Appl Chem. 1998 Feb; 70(2):263-6.
    View in: PubMed
    Score: 0.033
  13. Origin of life. RNA seeks its maker. Nature. 1995 Aug 17; 376(6541):548-9.
    View in: PubMed
    Score: 0.028
  14. Sin resolvase catalytic activity and oligomerization state are tightly coupled. J Mol Biol. 2010 Nov 19; 404(1):16-33.
    View in: PubMed
    Score: 0.020
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.