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Sarah K. Keedy

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentPsychiatry and Behavioral Neuroscience-Adult Psychiatry
AddressChicago IL 60637
Email
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    Collapse Overview 
    Collapse overview
    Dr. Keedy’s lab, the CENSL, focuses on cognitive and emotional neural systems - and their overlap - in psychiatric disorders. A major area of focus is psychotic disorders, and a major methodology is human neuroimaging.

    Collapse Biography 
    Collapse education and training
    Oklahoma State UniversityBS1997Psychology
    Rosalind Franklin University of Medicine and SciencePhD2004Clinical Psychology
    Jesse Brown VA Medical Center, ChicagoInternship2004Clinical Neuropsychology
    University of Illinois at ChicagoPostdoctoral Fellowship2006Neuropsychology, Psychopathology Research

    Collapse Research 
    Collapse research activities and funding
    R01MH124804     (GERSHON, ELLIOT S ;KEEDY, SARAH K)May 1, 2021 - Apr 30, 2026
    NIH
    2/5-Clozapine Response and Biomarker Correlates in Low-IEA Biotype-1
    Role: Principle Investigator (Multiple PI plan)

    R01MH103368     (GERSHON, ELLIOT S)Jul 1, 2015 - Mar 31, 2021
    NIH
    2/5 Bipolar-Schizophrenia Network for Intermediate Phenotypes 2 (B-SNIP2)
    Role: Principle Investigator (Multiple PI plan)

    K23MH092702     (KEEDY, SARAH)Jan 1, 2011 - Nov 30, 2015
    NIH
    Antipsychotic Effects on Top Down Control of Sensory Processing in Schizophrenia
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Abram SV, Hua JPY, Nicholas S, Roach B, Keedy S, Sweeney JA, Mathalon DH, Ford JM. Pons-to-cerebellum hypoconnectivity along the psychosis spectrum and associations with sensory prediction and hallucinations in schizophrenia. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Feb 02. PMID: 38311290.
      Citations:    Fields:    
    2. Clementz BA, Chattopadhyay I, Trotti RL, Parker DA, Gershon ES, Hill SK, Ivleva EI, Keedy SK, Keshavan MS, McDowell JE, Pearlson GD, Tamminga CA, Gibbons RD. Clinical characterization and differentiation of B-SNIP psychosis Biotypes: Algorithmic Diagnostics for Efficient Prescription of Treatments (ADEPT)-1. Schizophr Res. 2023 10; 260:143-151. PMID: 37657281; PMCID: PMC10712427.
      Citations:    Fields:    Translation:Humans
    3. Han J, Keedy S, de Wit H. Stimulant-like subjective effects of alcohol are not related to resting-state connectivity in healthy men. Cereb Cortex. 2023 08 08; 33(16):9478-9488. PMID: 37339883; PMCID: PMC10656944.
      Citations:    Fields:    Translation:Humans
    4. Lizano P, Kiely C, Mijalkov M, Meda SA, Keedy SK, Hoang D, Zeng V, Lutz O, Pereira JB, Ivleva EI, Volpe G, Xu Y, Lee AM, Rubin LH, Kristian Hill S, Clementz BA, Tamminga CA, Pearlson GD, Sweeney JA, Gershon ES, Keshavan MS, Bishop JR. Peripheral inflammatory subgroup differences in anterior Default Mode network and multiplex functional network topology are associated with cognition in psychosis. Brain Behav Immun. 2023 11; 114:3-15. PMID: 37506949; PMCID: PMC10592140.
      Citations:    Fields:    Translation:Humans
    5. Molla H, Keedy S, DeBrosse J, de Wit H. Methamphetamine enhances neural activation during anticipation of loss in the monetary incentive delay task. Cereb Cortex Commun. 2023; 4(3):tgad014. PMID: 37565072; PMCID: PMC10412021.
      Citations:    
    6. Del Re EC, Yassin W, Zeng V, Keedy S, Alliey-Rodriguez N, Ivleva E, Hill S, Rychagov N, McDowell JE, Bishop JR, Mesholam-Gately R, Merola G, Lizano P, Gershon E, Pearlson G, Sweeney JA, Clementz B, Tamminga C, Keshavan M. Characterization of childhood trauma, hippocampal mediation and Cannabis use in a large dataset of psychosis and non-psychosis individuals. Schizophr Res. 2023 05; 255:102-109. PMID: 36989667.
      Citations: 1     Fields:    Translation:HumansAnimals
    7. Zhang L, Lizano P, Xu Y, Rubin LH, Lee AM, Reilly JL, Keefe RSE, Keedy SK, Pearlson GD, Clementz BA, Keshavan MS, Gershon ES, Tamminga CA, Sweeney JA, Hill SK, Bishop JR, Lencer R. Peripheral inflammation is associated with impairments of inhibitory behavioral control and visual sensorimotor function in psychotic disorders. Schizophr Res. 2023 05; 255:69-78. PMID: 36965362; PMCID: PMC10175233.
      Citations: 1     Fields:    Translation:Humans
    8. Di Donato N, Guerrini R, Billington CJ, Barkovich AJ, Dinkel P, Freri E, Heide M, Gershon ES, Gertler TS, Hopkin RJ, Jacob S, Keedy SK, Kooshavar D, Lockhart PJ, Lohmann DR, Mahmoud IG, Parrini E, Schrock E, Severi G, Timms AE, Webster RI, Willis MJH, Zaki MS, Gleeson JG, Leventer RJ, Dobyns WB. Monoallelic and biallelic mutations in RELN underlie a graded series of neurodevelopmental disorders. Brain. 2022 09 14; 145(9):3274-3287. PMID: 35769015; PMCID: PMC9989350.
      Citations: 2     Fields:    Translation:Humans
    9. Coccaro EF, Keedy S, Malina M, Lee R, Phan KL. Neuronal responses in social-emotional information processing in impulsive aggressive individuals. Neuropsychopharmacology. 2022 05; 47(6):1249-1255. PMID: 35277651; PMCID: PMC9018744.
      Citations: 1     Fields:    Translation:Humans
    10. Zhao Q, Cao H, Zhang W, Li S, Xiao Y, Tamminga CA, Keshavan MS, Pearlson GD, Clementz BA, Gershon ES, Hill SK, Keedy SK, Ivleva EI, Sweeney JA, Gong Q, Lui S, Lencer R. A subtype of institutionalized patients with schizophrenia characterized by pronounced subcortical and cognitive deficits. Neuropsychopharmacology. 2022 11; 47(12):2024-2032. PMID: 35260788; PMCID: PMC9556672.
      Citations: 6     Fields:    Translation:Humans
    11. Tamminga CA, Pearlson G, Gershon E, Keedy S, Hudgens-Haney ME, Ivleva EI, Parker DA, McDowell JE, Clementz B. Using psychosis biotypes and the Framingham model for parsing psychosis biology. Schizophr Res. 2022 04; 242:132-134. PMID: 35123865.
      Citations:    Fields:    Translation:Humans
    12. Clementz BA, Parker DA, Trotti RL, McDowell JE, Keedy SK, Keshavan MS, Pearlson GD, Gershon ES, Ivleva EI, Huang LY, Hill SK, Sweeney JA, Thomas O, Hudgens-Haney M, Gibbons RD, Tamminga CA. Psychosis Biotypes: Replication and Validation from the B-SNIP Consortium. Schizophr Bull. 2022 01 21; 48(1):56-68. PMID: 34409449; PMCID: PMC8781330.
      Citations: 17     Fields:    Translation:Humans
    13. Xiao Y, Liao W, Long Z, Tao B, Zhao Q, Luo C, Tamminga CA, Keshavan MS, Pearlson GD, Clementz BA, Gershon ES, Ivleva EI, Keedy SK, Biswal BB, Mechelli A, Sweeney JA, Lui S, Gong Q, Lencer R. Subtyping Schizophrenia Patients Based on Patterns of Structural Brain Alterations. Schizophr Bull. 2022 01 21; 48(1):241-250. PMID: 34508358; PMCID: PMC8781382.
      Citations: 15     Fields:    Translation:Humans
    14. Rubin LH, Han J, Coughlin JM, Hill SK, Bishop JR, Tamminga CA, Clementz BA, Pearlson GD, Keshavan MS, Gershon ES, Heilman KJ, Porges SW, Sweeney JA, Keedy S. Real-time facial emotion recognition deficits across the psychosis spectrum: A B-SNIP Study. Schizophr Res. 2022 05; 243:489-499. PMID: 34887147; PMCID: PMC9236198.
      Citations: 2     Fields:    Translation:Humans
    15. Gotra MY, Keedy SK, Hill SK. Interactive effects of maintenance decay and interference on working memory updating in schizophrenia. Schizophr Res. 2022 01; 239:103-110. PMID: 34871994.
      Citations: 2     Fields:    Translation:Humans
    16. Lepping RJ, McKinney WS, Magnon GC, Keedy SK, Wang Z, Coombes SA, Vaillancourt DE, Sweeney JA, Mosconi MW. Visuomotor brain network activation and functional connectivity among individuals with autism spectrum disorder. Hum Brain Mapp. 2022 02 01; 43(2):844-859. PMID: 34716740; PMCID: PMC8720186.
      Citations: 8     Fields:    Translation:Humans
    17. Zhang L, Hill SK, Guo B, Wu B, Alliey-Rodriguez N, Eum S, Lizano P, Ivleva EI, Reilly JL, Keefe RSE, Keedy SK, Tamminga CA, Pearlson GD, Clementz BA, Keshavan MS, Gershon ES, Sweeney JA, Bishop JR. Impact of polygenic risk for coronary artery disease and cardiovascular medication burden on cognitive impairment in psychotic disorders. Prog Neuropsychopharmacol Biol Psychiatry. 2022 03 08; 113:110464. PMID: 34756932; PMCID: PMC8932335.
      Citations: 1     Fields:    Translation:Humans
    18. Malina M, Keedy S, Weafer J, Van Hedger K, de Wit H. Effects of Methamphetamine on Within- and Between-Network Connectivity in Healthy Adults. Cereb Cortex Commun. 2021; 2(4):tgab063. PMID: 34859242; PMCID: PMC8633740.
      Citations: 1     
    19. Ogbuagu N, Keedy S, Phan KL, Coccaro EF. Neural responses to induced emotion and response to social threat in intermittent explosive disorder. Psychiatry Res Neuroimaging. 2021 12 30; 318:111388. PMID: 34706324.
      Citations: 1     Fields:    Translation:Humans
    20. Trotti RL, Abdelmageed S, Parker DA, Sabatinelli D, Tamminga CA, Gershon ES, Keedy SK, Keshavan MS, Pearlson GD, Sweeney JA, McDowell JE, Clementz BA. Neural Processing of Repeated Emotional Scenes in Schizophrenia, Schizoaffective Disorder, and Bipolar Disorder. Schizophr Bull. 2021 08 21; 47(5):1473-1481. PMID: 33693875; PMCID: PMC8379546.
      Citations: 3     Fields:    Translation:Humans
    21. Parker DA, Trotti RL, McDowell JE, Keedy SK, Hill SK, Gershon ES, Ivleva EI, Pearlson GD, Keshavan MS, Tamminga CA, Clementz BA. Auditory Oddball Responses Across the Schizophrenia-Bipolar Spectrum and Their Relationship to Cognitive and Clinical Features. Am J Psychiatry. 2021 10 01; 178(10):952-964. PMID: 34407624.
      Citations: 7     Fields:    Translation:Humans
    22. Eskridge CLM, Hochberger WC, Kaseda ET, Lencer R, Reilly JL, Keedy SK, Keefe RSE, Pearlson GD, Keshavan MS, Tamminga CA, Sweeney JA, Hill SK. Deficits in generalized cognitive ability, visual sensorimotor function, and inhibitory control represent discrete domains of neurobehavioral deficit in psychotic disorders. Schizophr Res. 2021 10; 236:54-60. PMID: 34392106; PMCID: PMC8464494.
      Citations: 2     Fields:    Translation:Humans
    23. Gershon ES, Lee SH, Zhou X, Sweeney JA, Tamminga C, Pearlson GA, Clementz BA, Keshavan MS, Alliey-Rodriguez N, Hudgens-Haney M, Keedy SK, Glahn DC, Asif H, Lencer R, Hill SK. An opportunity for primary prevention research in psychotic disorders. Schizophr Res. 2022 05; 243:433-439. PMID: 34315649; PMCID: PMC8784565.
      Citations:    Fields:    Translation:HumansPHPublic Health
    24. Eum S, Hill SK, Alliey-Rodriguez N, Stevenson JM, Rubin LH, Lee AM, Mills LJ, Reilly JL, Lencer R, Keedy SK, Ivleva E, Keefe RSE, Pearlson GD, Clementz BA, Tamminga CA, Keshavan MS, Gershon ES, Sweeney JA, Bishop JR. Genome-wide association study accounting for anticholinergic burden to examine cognitive dysfunction in psychotic disorders. Neuropsychopharmacology. 2021 09; 46(10):1802-1810. PMID: 34145405; PMCID: PMC8358015.
      Citations: 11     Fields:    Translation:Humans
    25. Coccaro EF, Keedy S, Lee R, Phan KL. Neuronal responses to adverse social threat in healthy human subjects. J Psychiatr Res. 2021 04; 136:47-53. PMID: 33556904; PMCID: PMC10262305.
      Citations: 2     Fields:    Translation:Humans
    26. Han J, Keedy S, Murray CH, Foxley S, de Wit H. Acute effects of alcohol on resting-state functional connectivity in healthy young men. Addict Behav. 2021 04; 115:106786. PMID: 33421747; PMCID: PMC8693384.
      Citations: 9     Fields:    Translation:Humans
    27. Lizano P, Lutz O, Xu Y, Rubin LH, Paskowitz L, Lee AM, Eum S, Keedy SK, Hill SK, Reilly JL, Wu B, Tamminga CA, Clementz BA, Pearlson GD, Gershon ES, Keshavan MS, Sweeney JA, Bishop JR. Multivariate relationships between peripheral inflammatory marker subtypes and cognitive and brain structural measures in psychosis. Mol Psychiatry. 2021 07; 26(7):3430-3443. PMID: 33060818; PMCID: PMC8046847.
      Citations: 38     Fields:    Translation:Humans
    28. Tamminga CA, Clementz BA, Pearlson G, Keshavan M, Gershon ES, Ivleva EI, McDowell J, Meda SA, Keedy S, Calhoun VD, Lizano P, Bishop JR, Hudgens-Haney M, Alliey-Rodriguez N, Asif H, Gibbons R. Biotyping in psychosis: using multiple computational approaches with one data set. Neuropsychopharmacology. 2021 01; 46(1):143-155. PMID: 32979849; PMCID: PMC7689458.
      Citations: 14     Fields:    Translation:Humans
    29. Cremers H, Keedy S, Coccaro E. The development of an fMRI protocol to investigate vmPFC network functioning underlying the generalization of behavioral control. Psychiatry Res Neuroimaging. 2021 01 30; 307:111197. PMID: 33077339.
      Citations: 2     Fields:    Translation:HumansAnimals
    30. Hudgens-Haney ME, Clementz BA, Ivleva EI, Keshavan MS, Pearlson GD, Gershon ES, Keedy SK, Sweeney JA, Gaudoux F, Bunouf P, Canolle B, Gatti-McArthur S, Tamminga CA, Tonner F, Hudgens-Haney ME. Cognitive Impairment and Diminished Neural Responses Constitute a Biomarker Signature of Negative Symptoms in Psychosis. Schizophr Bull. 2020 Sep 21; 46(5):1269-1281. PMID: 32043133; PMCID: PMC7505197.
      Citations: 8     Fields:    
    31. Hochberger WC, Eskridge CLM, Bishop JR, Reilly JL, Rubin LH, Keedy S, Gershon ES, Tamminga CA, Pearlson GD, Ragozzino M, Keshavan MS, Sweeney JA, Hill SK. Catechol-O-methyltransferase genotype differentially contributes to the flexibility and stability of cognitive sets in patients with psychotic disorders and their first-degree relatives. Schizophr Res. 2020 09; 223:236-241. PMID: 32829984; PMCID: PMC7704884.
      Citations:    Fields:    Translation:Humans
    32. Okuneye VT, Meda S, Pearlson GD, Clementz BA, Keshavan MS, Tamminga CA, Ivleva E, Sweeney JA, Gershon ES, Keedy SK. Resting state auditory-language cortex connectivity is associated with hallucinations in clinical and biological subtypes of psychotic disorders. Neuroimage Clin. 2020; 27:102358. PMID: 32745995; PMCID: PMC7398970.
      Citations: 2     Fields:    Translation:Humans
    33. Gotra MY, Hill SK, Gershon ES, Tamminga CA, Ivleva EI, Pearlson GD, Keshavan MS, Clementz BA, McDowell JE, Buckley PF, Sweeney JA, Keedy SK. Distinguishing patterns of impairment on inhibitory control and general cognitive ability among bipolar with and without psychosis, schizophrenia, and schizoaffective disorder. Schizophr Res. 2020 09; 223:148-157. PMID: 32674921; PMCID: PMC7704797.
      Citations: 8     Fields:    Translation:Humans
    34. Herms EN, Bishop JR, Okuneye VT, Tamminga CA, Keshavan MS, Pearlson GD, Clementz BA, McDowell JE, Ivleva EI, Gershon ES, Sweeney JA, Keedy SK. No connectivity alterations for striatum, default mode, or salience network in association with self-reported antipsychotic medication dose in a large chronic patient group. Schizophr Res. 2020 09; 223:359-360. PMID: 32624351; PMCID: PMC8082971.
      Citations:    Fields:    Translation:Humans
    35. Parker DA, Trotti RL, McDowell JE, Keedy SK, Gershon ES, Ivleva EI, Pearlson GD, Keshavan MS, Tamminga CA, Sweeney JA, Clementz BA. Auditory paired-stimuli responses across the psychosis and bipolar spectrum and their relationship to clinical features. Biomark Neuropsychiatry. 2020 Dec; 3. PMID: 36644018; PMCID: PMC9837793.
      Citations: 2     
    36. Clementz BA, Trotti RL, Pearlson GD, Keshavan MS, Gershon ES, Keedy SK, Ivleva EI, McDowell JE, Tamminga CA. Testing Psychosis Phenotypes From Bipolar-Schizophrenia Network for Intermediate Phenotypes for Clinical Application: Biotype Characteristics and Targets. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 08; 5(8):808-818. PMID: 32600898.
      Citations: 21     Fields:    Translation:Humans
    37. Asif H, Alliey-Rodriguez N, Keedy S, Tamminga CA, Sweeney JA, Pearlson G, Clementz BA, Keshavan MS, Buckley P, Liu C, Neale B, Gershon ES. GWAS significance thresholds for deep phenotyping studies can depend upon minor allele frequencies and sample size. Mol Psychiatry. 2021 06; 26(6):2048-2055. PMID: 32066829; PMCID: PMC7429341.
      Citations: 12     Fields:    Translation:Humans
    38. Blackburn KM, Ivleva EI, Weir RA, Kim M, Hopkins SC, Hudgens-Haney ME, Keedy SK, Gershon ES, Sweeney JA, Keshavan MS, Pearlson GD, Clementz BA, Tamminga CA, Vernino S. NMDA receptor antibody seropositivity in psychosis: A pilot study from the Bipolar-Schizophrenia Network for Intermediate Phenotypes (B-SNIP). Schizophr Res. 2020 04; 218:318-320. PMID: 31952910.
      Citations: 1     Fields:    Translation:Humans
    39. Bershad AK, Preller KH, Lee R, Keedy S, Wren-Jarvis J, Bremmer MP, de Wit H. Preliminary Report on the Effects of a Low Dose of LSD on Resting-State Amygdala Functional Connectivity. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 04; 5(4):461-467. PMID: 32033922; PMCID: PMC7150630.
      Citations: 27     Fields:    Translation:Humans
    40. Zhang W, Lei D, Keedy SK, Ivleva EI, Eum S, Yao L, Tamminga CA, Clementz BA, Keshavan MS, Pearlson GD, Gershon ES, Bishop JR, Gong Q, Lui S, Sweeney JA. Brain gray matter network organization in psychotic disorders. Neuropsychopharmacology. 2020 03; 45(4):666-674. PMID: 31812151; PMCID: PMC7021697.
      Citations: 16     Fields:    Translation:Humans
    41. Massa N, Owens AV, Harmon W, Bhattacharya A, Ivleva EI, Keedy S, Sweeney JA, Pearlson GD, Keshavan MS, Tamminga CA, Clementz BA, Duncan E. Relationship of prolonged acoustic startle latency to diagnosis and biotype in the bipolar-schizophrenia network on intermediate phenotypes (B-SNIP) cohort. Schizophr Res. 2020 02; 216:357-366. PMID: 31796306; PMCID: PMC7239737.
      Citations: 7     Fields:    Translation:Humans
    42. Thomas O, Parker D, Trotti R, McDowell J, Gershon E, Sweeney J, Keshavan MS, Keedy SK, Ivleva E, Tamminga CA, Pearlson GD, Clementz BA. Intrinsic neural activity differences in psychosis biotypes: Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) consortium. Biomark Neuropsychiatry. 2019 Dec; 1. PMID: 36643612; PMCID: PMC9837786.
      Citations: 3     
    43. Trotti RL, Parker DA, Sabatinelli D, Tamminga CA, Gershon ES, Keedy SK, Keshavan MS, Pearlson GD, Sweeney JA, McDowell JE, Clementz BA. Electrophysiological correlates of emotional scene processing in bipolar disorder. J Psychiatr Res. 2020 01; 120:83-90. PMID: 31634753; PMCID: PMC10499256.
      Citations: 5     Fields:    Translation:Humans
    44. Alliey-Rodriguez N, Grey TA, Shafee R, Asif H, Lutz O, Bolo NR, Padmanabhan J, Tandon N, Klinger M, Reis K, Spring J, Coppes L, Zeng V, Hegde RR, Hoang DT, Bannai D, Nawaz U, Henson P, Liu S, Gage D, McCarroll S, Bishop JR, Hill S, Reilly JL, Lencer R, Clementz BA, Buckley P, Glahn DC, Meda SA, Narayanan B, Pearlson G, Keshavan MS, Ivleva EI, Tamminga C, Sweeney JA, Curtis D, Badner JA, Keedy S, Rapoport J, Liu C, Gershon ES. NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Transl Psychiatry. 2019 09 17; 9(1):230. PMID: 31530798; PMCID: PMC6748921.
      Citations: 13     Fields:    Translation:Humans
    45. Weafer J, Van Hedger K, Keedy SK, Nwaokolo N, de Wit H. Methamphetamine acutely alters frontostriatal resting state functional connectivity in healthy young adults. Addict Biol. 2020 05; 25(3):e12775. PMID: 31099141; PMCID: PMC6527344.
      Citations: 10     Fields:    Translation:Humans
    46. Parker DA, Hamm JP, McDowell JE, Keedy SK, Gershon ES, Ivleva EI, Pearlson GD, Keshavan MS, Tamminga CA, Sweeney JA, Clementz BA. Auditory steady-state EEG response across the schizo-bipolar spectrum. Schizophr Res. 2019 07; 209:218-226. PMID: 31080153; PMCID: PMC6661193.
      Citations: 23     Fields:    Translation:Humans
    47. Van Hedger K, Keedy SK, Schertz KE, Berman MG, de Wit H. Effects of methamphetamine on neural responses to visual stimuli. Psychopharmacology (Berl). 2019 Jun; 236(6):1741-1748. PMID: 30604184; PMCID: PMC6606378.
      Citations: 5     Fields:    Translation:Humans
    48. Lencer R, Yao L, Reilly JL, Keedy SK, McDowell JE, Keshavan MS, Pearlson GD, Tamminga CA, Gershon ES, Clementz BA, Lui S, Sweeney JA. Alterations in intrinsic fronto-thalamo-parietal connectivity are associated with cognitive control deficits in psychotic disorders. Hum Brain Mapp. 2019 01; 40(1):163-174. PMID: 30260540; PMCID: PMC6289604.
      Citations: 7     Fields:    Translation:Humans
    49. Goldschmidt AB, Dickstein DP, MacNamara AE, Phan KL, O'Brien S, Le Grange D, Fisher JO, Keedy S. A Pilot Study of Neural Correlates of Loss of Control Eating in Children With Overweight/Obesity: Probing Intermittent Access to Food as a Means of Eliciting Disinhibited Eating. J Pediatr Psychol. 2018 09 01; 43(8):846-855. PMID: 29462339; PMCID: PMC6093382.
      Citations: 11     Fields:    Translation:Humans
    50. Rubin LH, Li S, Yao L, Keedy SK, Reilly JL, Hill SK, Bishop JR, Sue Carter C, Pournajafi-Nazarloo H, Drogos LL, Gershon E, Pearlson GD, Tamminga CA, Clementz BA, Keshavan MS, Lui S, Sweeney JA. Peripheral oxytocin and vasopressin modulates regional brain activity differently in men and women with schizophrenia. Schizophr Res. 2018 12; 202:173-179. PMID: 30539769; PMCID: PMC6293995.
      Citations: 10     Fields:    Translation:Humans
    51. Zhang W, Li S, Wang X, Gong Y, Yao L, Xiao Y, Liu J, Keedy SK, Gong Q, Sweeney JA, Lui S. Abnormal dynamic functional connectivity between speech and auditory areas in schizophrenia patients with auditory hallucinations. Neuroimage Clin. 2018; 19:918-924. PMID: 30003029; PMCID: PMC6039841.
      Citations: 23     Fields:    Translation:Humans
    52. Van Hedger K, Keedy SK, de Wit H, Mayo LM, Heilig M. Neural responses to cues paired with methamphetamine in healthy volunteers. Neuropsychopharmacology. 2018 07; 43(8):1732-1737. PMID: 29463908; PMCID: PMC6006246.
      Citations: 6     Fields:    Translation:Humans
    53. Coccaro EF, Cremers H, Fanning J, Nosal E, Lee R, Keedy S, Jacobson KC. Reduced frontal grey matter, life history of aggression, and underlying genetic influence. Psychiatry Res Neuroimaging. 2018 01 30; 271:126-134. PMID: 29174436.
      Citations: 5     Fields:    Translation:Humans
    54. Gershon ES, Pearlson G, Keshavan MS, Tamminga C, Clementz B, Buckley PF, Alliey-Rodriguez N, Liu C, Sweeney JA, Keedy S, Meda SA, Tandon N, Shafee R, Bishop JR, Ivleva EI. Genetic analysis of deep phenotyping projects in common disorders. Schizophr Res. 2018 05; 195:51-57. PMID: 29056493; PMCID: PMC5910299.
      Citations: 5     Fields:    Translation:Humans
    55. Hudgens-Haney ME, Ethridge LE, McDowell JE, Keedy SK, Pearlson GD, Tamminga CA, Keshavan MS, Sweeney JA, Clementz BA. Psychosis subgroups differ in intrinsic neural activity but not task-specific processing. Schizophr Res. 2018 05; 195:222-230. PMID: 28844436; PMCID: PMC5826774.
      Citations: 3     Fields:    Translation:Humans
    56. Fanning JR, Keedy S, Berman ME, Lee R, Coccaro EF. Neural Correlates of Aggressive Behavior in Real Time: a Review of fMRI Studies of Laboratory Reactive Aggression. Curr Behav Neurosci Rep. 2017 Jun; 4(2):138-150. PMID: 29607288; PMCID: PMC5875983.
      Citations: 20     
    57. Rosen C, Jones N, Longden E, Chase KA, Shattell M, Melbourne JK, Keedy SK, Sharma RP. Exploring the Intersections of Trauma, Structural Adversity, and Psychosis among a Primarily African-American Sample: A Mixed-Methods Analysis. Front Psychiatry. 2017; 8:57. PMID: 28469582; PMCID: PMC5395710.
      Citations: 8     
    58. Hudgens-Haney ME, Ethridge LE, Knight JB, McDowell JE, Keedy SK, Pearlson GD, Tamminga CA, Keshavan MS, Sweeney JA, Clementz BA. Intrinsic neural activity differences among psychotic illnesses. Psychophysiology. 2017 Aug; 54(8):1223-1238. PMID: 28419491; PMCID: PMC5507732.
      Citations: 6     Fields:    Translation:Humans
    59. Eum S, Hill SK, Rubin LH, Carnahan RM, Reilly JL, Ivleva EI, Keedy SK, Tamminga CA, Pearlson GD, Clementz BA, Gershon ES, Keshavan MS, Keefe RSE, Sweeney JA, Bishop JR. Cognitive burden of anticholinergic medications in psychotic disorders. Schizophr Res. 2017 12; 190:129-135. PMID: 28390849; PMCID: PMC5628100.
      Citations: 36     Fields:    Translation:Humans
    60. Rubin LH, Yao L, Keedy SK, Reilly JL, Bishop JR, Carter CS, Pournajafi-Nazarloo H, Drogos LL, Tamminga CA, Pearlson GD, Keshavan MS, Clementz BA, Hill SK, Liao W, Ji GJ, Lui S, Sweeney JA. Sex differences in associations of arginine vasopressin and oxytocin with resting-state functional brain connectivity. J Neurosci Res. 2017 01 02; 95(1-2):576-586. PMID: 27870395; PMCID: PMC5120603.
      Citations: 13     Fields:    Translation:Humans
    61. Coccaro EF, Keedy SK, Gorka SM, King AC, Fanning JR, Lee RJ, Phan KL. Differential fMRI BOLD responses in amygdala in intermittent explosive disorder as a function of past Alcohol Use Disorder. Psychiatry Res Neuroimaging. 2016 Nov 30; 257:5-10. PMID: 27693977; PMCID: PMC6323646.
      Citations: 1     Fields:    Translation:Humans
    62. Coccaro EF, Fanning JR, Keedy SK, Lee RJ. Social cognition in Intermittent Explosive Disorder and aggression. J Psychiatr Res. 2016 12; 83:140-150. PMID: 27621104; PMCID: PMC5744876.
      Citations: 11     Fields:    Translation:Humans
    63. Lee R, Arfanakis K, Evia AM, Fanning J, Keedy S, Coccaro EF. White Matter Integrity Reductions in Intermittent Explosive Disorder. Neuropsychopharmacology. 2016 10; 41(11):2697-703. PMID: 27206265; PMCID: PMC5026737.
      Citations: 10     Fields:    Translation:Humans
    64. McCloskey MS, Phan KL, Angstadt M, Fettich KC, Keedy S, Coccaro EF. Amygdala hyperactivation to angry faces in intermittent explosive disorder. J Psychiatr Res. 2016 08; 79:34-41. PMID: 27145325.
      Citations: 29     Fields:    Translation:Humans
    65. Rubin LH, Connelly JJ, Reilly JL, Carter CS, Drogos LL, Pournajafi-Nazarloo H, Ruocco AC, Keedy SK, Matthew I, Tandon N, Pearlson GD, Clementz BA, Tamminga CA, Gershon ES, Keshavan MS, Bishop JR, Sweeney JA. Sex and diagnosis specific associations between DNA methylation of the oxytocin receptor gene with emotion processing and temporal-limbic and prefrontal brain volumes in psychotic disorders. Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 Mar 01; 1(2):141-151. PMID: 26977453; PMCID: PMC4788596.
      Citations: 31     Fields:    
    66. Cremers H, Lee R, Keedy S, Phan KL, Coccaro E. Effects of Escitalopram Administration on Face Processing in Intermittent Explosive Disorder: An fMRI Study. Neuropsychopharmacology. 2016 Jan; 41(2):590-7. PMID: 26105140; PMCID: PMC5130134.
      Citations: 8     Fields:    Translation:Humans
    67. Keedy SK, Bishop JR, Weiden PJ, Sweeney JA, Rosen C, Marvin R, Reilly JL. Disease and drug effects on internally-generated and externally-elicited responses in first episode schizophrenia and psychotic bipolar disorder. Schizophr Res. 2014 Oct; 159(1):101-6. PMID: 25112158; PMCID: PMC4177289.
      Citations: 5     Fields:    Translation:Humans
    68. Woodward TS, Jung K, Yin J, Taylor L, Menon M, Peters E, Kuipers E, Waters F, Sommer IE, Daalman K, van Lutterveld R, Hubl D, Kindler J, Homan P, Badcock JC, Chhabra S, Cella M, Keedy S, Allen P, Mechelli A, Preti A, Siddi S, Erickson D, Hwang H, Lecomte T. Symptom dimensions of the psychotic symptom rating scales in psychosis: a multisite study. Schizophr Bull. 2014 Jul; 40 Suppl 4:S265-74. PMID: 24936086; PMCID: PMC4141314.
      Citations: 38     Fields:    Translation:Humans
    69. Keedy SK, Reilly JL, Bishop JR, Weiden PJ, Sweeney JA. Impact of antipsychotic treatment on attention and motor learning systems in first-episode schizophrenia. Schizophr Bull. 2015 Mar; 41(2):355-65. PMID: 24894883; PMCID: PMC4332935.
      Citations: 17     Fields:    Translation:Humans
    70. Ford JM, Morris SE, Hoffman RE, Sommer I, Waters F, McCarthy-Jones S, Thoma RJ, Turner JA, Keedy SK, Badcock JC, Cuthbert BN. Studying hallucinations within the NIMH RDoC framework. Schizophr Bull. 2014 Jul; 40 Suppl 4:S295-304. PMID: 24847862; PMCID: PMC4141312.
      Citations: 51     Fields:    Translation:Humans
    71. Lui S, Yao L, Xiao Y, Keedy SK, Reilly JL, Keefe RS, Tamminga CA, Keshavan MS, Pearlson GD, Gong Q, Sweeney JA. Resting-state brain function in schizophrenia and psychotic bipolar probands and their first-degree relatives. Psychol Med. 2015 Jan; 45(1):97-108. PMID: 25066779; PMCID: PMC5836742.
      Citations: 61     Fields:    Translation:Humans
    72. Rubin LH, Carter CS, Bishop JR, Pournajafi-Nazarloo H, Drogos LL, Hill SK, Ruocco AC, Keedy SK, Reilly JL, Keshavan MS, Pearlson GD, Tamminga CA, Gershon ES, Sweeney JA. Reduced levels of vasopressin and reduced behavioral modulation of oxytocin in psychotic disorders. Schizophr Bull. 2014 Nov; 40(6):1374-84. PMID: 24619535; PMCID: PMC4193712.
      Citations: 34     Fields:    Translation:Humans
    73. Wang J, Mathalon DH, Roach BJ, Reilly J, Keedy SK, Sweeney JA, Ford JM. Action planning and predictive coding when speaking. Neuroimage. 2014 May 01; 91:91-8. PMID: 24423729; PMCID: PMC3965634.
      Citations: 38     Fields:    Translation:Humans
    74. Ford JM, Mathalon DH, Roach BJ, Keedy SK, Reilly JL, Gershon ES, Sweeney JA. Neurophysiological evidence of corollary discharge function during vocalization in psychotic patients and their nonpsychotic first-degree relatives. Schizophr Bull. 2013 Nov; 39(6):1272-80. PMID: 23155183; PMCID: PMC3796076.
      Citations: 24     Fields:    Translation:Humans
    75. Rosen C, Marvin R, Reilly JL, Deleon O, Harris MS, Keedy SK, Solari H, Weiden P, Sweeney JA. Phenomenology of first-episode psychosis in schizophrenia, bipolar disorder, and unipolar depression: a comparative analysis. Clin Schizophr Relat Psychoses. 2012 Oct; 6(3):145-51. PMID: 23006239.
      Citations: 29     Fields:    Translation:Humans
    76. Lu LH, Zhou XJ, Fitzgerald J, Keedy SK, Reilly JL, Passarotti AM, Sweeney JA, Pavuluri M. Microstructural abnormalities of white matter differentiate pediatric and adult-onset bipolar disorder. Bipolar Disord. 2012 Sep; 14(6):597-606. PMID: 22882719; PMCID: PMC3612992.
      Citations: 20     Fields:    Translation:HumansCells
    77. Ethridge LE, Hamm JP, Shapiro JR, Summerfelt AT, Keedy SK, Stevens MC, Pearlson G, Tamminga CA, Boutros NN, Sweeney JA, Keshavan MS, Thaker G, Clementz BA. Neural activations during auditory oddball processing discriminating schizophrenia and psychotic bipolar disorder. Biol Psychiatry. 2012 Nov 01; 72(9):766-74. PMID: 22572033; PMCID: PMC3465513.
      Citations: 28     Fields:    Translation:Humans
    78. Lu LH, Zhou XJ, Keedy SK, Reilly JL, Sweeney JA. White matter microstructure in untreated first episode bipolar disorder with psychosis: comparison with schizophrenia. Bipolar Disord. 2011 Nov-Dec; 13(7-8):604-13. PMID: 22085473; PMCID: PMC3612986.
      Citations: 41     Fields:    Translation:HumansCells
    79. Lencer R, Keedy SK, Reilly JL, McDonough BE, Harris MS, Sprenger A, Sweeney JA. Altered transfer of visual motion information to parietal association cortex in untreated first-episode psychosis: implications for pursuit eye tracking. Psychiatry Res. 2011 Oct 31; 194(1):30-8. PMID: 21873035; PMCID: PMC3185164.
      Citations: 22     Fields:    Translation:Humans
    80. Goldman MB, Wang L, Wachi C, Daudi S, Csernansky J, Marlow-O'Connor M, Keedy S, Torres I. Structural pathology underlying neuroendocrine dysfunction in schizophrenia. Behav Brain Res. 2011 Mar 17; 218(1):106-13. PMID: 21093493; PMCID: PMC4465073.
      Citations: 12     Fields:    Translation:Humans
    81. Clementz BA, Gao Y, McDowell JE, Moratti S, Keedy SK, Sweeney JA. Top-down control of visual sensory processing during an ocular motor response inhibition task. Psychophysiology. 2010 Nov; 47(6):1011-8. PMID: 20477977; PMCID: PMC2925050.
      Citations: 6     Fields:    Translation:Humans
    82. Ramati A, Pliskin NH, Keedy S, Erwin RJ, Fink JW, Bodnar EN, Lee RC, Cooper MA, Kelley K, Sweeney JA. Alteration in functional brain systems after electrical injury. J Neurotrauma. 2009 Oct; 26(10):1815-22. PMID: 19323610; PMCID: PMC6468944.
      Citations: 6     Fields:    Translation:Humans
    83. Torres IJ, Keedy S, Marlow-O'Connor M, Beenken B, Goldman MB. Neuropsychological impairment in patients with schizophrenia and evidence of hyponatremia and polydipsia. Neuropsychology. 2009 May; 23(3):307-14. PMID: 19413445.
      Citations: 6     Fields:    Translation:Humans
    84. Keedy SK, Rosen C, Khine T, Rajarethinam R, Janicak PG, Sweeney JA. An fMRI study of visual attention and sensorimotor function before and after antipsychotic treatment in first-episode schizophrenia. Psychiatry Res. 2009 Apr 30; 172(1):16-23. PMID: 19243925; PMCID: PMC2694499.
      Citations: 28     Fields:    Translation:Humans
    85. Reilly JL, Lencer R, Bishop JR, Keedy S, Sweeney JA. Pharmacological treatment effects on eye movement control. Brain Cogn. 2008 Dec; 68(3):415-35. PMID: 19028266; PMCID: PMC3159189.
      Citations: 97     Fields:    Translation:Humans
    86. Sweeney JA, Luna B, Keedy SK, McDowell JE, Clementz BA. fMRI studies of eye movement control: investigating the interaction of cognitive and sensorimotor brain systems. Neuroimage. 2007; 36 Suppl 2:T54-60. PMID: 17499170; PMCID: PMC2692203.
      Citations: 37     Fields:    Translation:HumansAnimals
    87. Goldman MB, Torres IJ, Keedy S, Marlow-O'Connor M, Beenken B, Pilla R. Reduced anterior hippocampal formation volume in hyponatremic schizophrenic patients. Hippocampus. 2007; 17(7):554-62. PMID: 17427242.
      Citations: 25     Fields:    Translation:Humans
    88. Keedy SK, Marlow-O'Connor M, Beenken B, Dorflinger J, Abel M, Erwin RJ. Noradrenergic antagonism of the P13 and N40 components of the rat auditory evoked potential. Psychopharmacology (Berl). 2007 Jan; 190(1):117-25. PMID: 17096083.
      Citations: 2     Fields:    Translation:AnimalsCells
    89. Keedy SK, Ebens CL, Keshavan MS, Sweeney JA. Functional magnetic resonance imaging studies of eye movements in first episode schizophrenia: smooth pursuit, visually guided saccades and the oculomotor delayed response task. Psychiatry Res. 2006 Apr 30; 146(3):199-211. PMID: 16571373.
      Citations: 40     Fields:    Translation:Humans
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