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Bernhard Ortel

TitleClinical Professor
InstitutionUniversity of Chicago
DepartmentMedicine
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ortel B, Jabeen S, Greer A. Adjuvants that Empower the Action of Photodynamic Therapy. Photochem Photobiol. 2020 Feb 28. PMID: 32109321.
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    2. Calzavara-Pinton P, Zanca A, Arisi M, Rossi MT, Zane C, Venturini M, Ortel B. Prevalence of Phototherapy in the Age of Biologics. Dermatology. 2018; 234(5-6):166-172. PMID: 30205372.
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    3. Schadler ED, Mehlis SL, Cibull TL, Ortel B. Two cases of treatment with aromatase inhibitors and development of miliary osteoma cutis-Is there an association? JAAD Case Rep. 2018 Aug; 4(7):648-650. PMID: 30094308.
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    4. Schadler ED, Ortel B, Mehlis SL. Biologics for the primary care physician: Review and treatment of psoriasis. Dis Mon. 2019 Mar; 65(3):51-90. PMID: 30037762.
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    5. Zane C, Facchinetti E, Arisi M, Ortel B, Calzavara-Pinton P. Pulsed CO2 Laser Ablation of Superficial Basal Cell of Limbs and Trunk: A Comparative Randomized Clinical Trial With Cryotherapy and Surgical Ablation. Dermatol Surg. 2017 Jul; 43(7):920-927. PMID: 28291062.
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    6. Calzavara-Pinton P, Ortel B, Venturini M. Non-melanoma skin cancer, sun exposure and sun protection. G Ital Dermatol Venereol. 2015 Aug; 150(4):369-78. PMID: 26186380.
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    7. Zane C, Facchinetti E, Rossi MT, Specchia C, Ortel B, Calzavara-Pinton P. Cryotherapy is preferable to ablative CO2 laser for the treatment of isolated actinic keratoses of the face and scalp: a randomized clinical trial. Br J Dermatol. 2014 May; 170(5):1114-21. PMID: 24472087.
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    8. Clarke M, Ortel B, Brockstein B, Rojanapremsuk T, Victor T, Thomas A, Cibull T. Bilateral areolar leiomyomas in a patient undergoing BRAF inhibition therapy for melanoma. J Cutan Pathol. 2013 Oct; 40(10):884-6. PMID: 23924408.
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    9. Calzavara-Pinton PG, Sala R, Arisi M, Rossi MT, Venturini M, Ortel B. Synergism between narrowband ultraviolet B phototherapy and etanercept for the treatment of plaque-type psoriasis. Br J Dermatol. 2013 Jul; 169(1):130-6. PMID: 23834117.
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    10. Maytin EV, Honari G, Khachemoune A, Taylor CR, Ortel B, Pogue BW, Sznycer-Taub N, Hasan T. Vitamin D Combined with Aminolevulinate (ALA)-Mediated Photodynamic Therapy (PDT) for Human Psoriasis: A Proof-of-Principle Study. Isr J Chem. 2012 Sep; 52(8-9):767-775. PMID: 23264699.
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    11. Anand S, Ortel BJ, Pereira SP, Hasan T, Maytin EV. Biomodulatory approaches to photodynamic therapy for solid tumors. Cancer Lett. 2012 Dec 29; 326(1):8-16. PMID: 22842096.
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    12. Kaminska EC, Ortel B, Sharma V, Stein SL. Narrowband UVB phototherapy as a novel treatment for Netherton syndrome. Photodermatol Photoimmunol Photomed. 2012 Jun; 28(3):162-4. PMID: 22548400.
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    13. Ortel B, Calzavara-Pinton P. Advances in photodynamic therapy. A review. G Ital Dermatol Venereol. 2010 Aug; 145(4):461-75. PMID: 20823790.
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    14. Bolotin D, Ortel B, Stein SL. Poorly growing hair in a child. Skinmed. 2010 Jul-Aug; 8(4):246-7. PMID: 21137616.
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    15. Calzavara-Pinton P, Piergiacomo CP, Arisi M, Mariachiara A, Sereni E, Elena S, Ortel B, Bernhard O. A critical reappraisal of off-label indications for topical photodynamic therapy with aminolevulinic acid and methylaminolevulinate. Rev Recent Clin Trials. 2010 May; 5(2):112-6. PMID: 20199385.
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    16. Ortel B, Shea CR, Calzavara-Pinton P. Molecular mechanisms of photodynamic therapy. Front Biosci (Landmark Ed). 2009 Jan 01; 14:4157-72. PMID: 19273342.
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    17. Casas A, Perotti C, Ortel B, Di Venosa G, Saccoliti M, Batlle A, Hasan T. Tumor cell lines resistant to ALA-mediated photodynamic therapy and possible tools to target surviving cells. Int J Oncol. 2006 Aug; 29(2):397-405. PMID: 16820882.
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    18. Sinha AK, Anand S, Ortel BJ, Chang Y, Mai Z, Hasan T, Maytin EV. Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells. Br J Cancer. 2006 Aug 21; 95(4):485-95. PMID: 16868543.
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    19. Kosaka S, Kawana S, Zouboulis CC, Hasan T, Ortel B. Targeting of sebocytes by aminolevulinic acid-dependent photosensitization. Photochem Photobiol. 2006 Mar-Apr; 82(2):453-7. PMID: 16613498.
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    20. Solban N, Ortel B, Pogue B, Hasan T. Targeted optical imaging and photodynamic therapy. Ernst Schering Res Found Workshop. 2005; (49):229-58. PMID: 15524219.
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    21. Jung K, Krell HW, Ortel B, Hasan T, Römer A, Schnorr D, Loening SA, Lein M. Plasma matrix metalloproteinase 9 as biomarker of prostate cancer progression in Dunning (Copenhagen) rats. Prostate. 2003 Feb 15; 54(3):206-11. PMID: 12518325.
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    22. Ortel B, Sharlin D, O'Donnell D, Sinha AK, Maytin EV, Hasan T. Differentiation enhances aminolevulinic acid-dependent photodynamic treatment of LNCaP prostate cancer cells. Br J Cancer. 2002 Nov 18; 87(11):1321-7. PMID: 12439724.
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    23. Duska LR, Wimberly J, Deutsch TF, Ortel B, Haas J, Houck K, Hasan T. Detection of female lower genital tract dysplasia using orally administered 5-aminolevulinic acid induced protoporphyrin IX: a preliminary study. Gynecol Oncol. 2002 Apr; 85(1):125-8. PMID: 11925131.
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    24. Lein M, Jung K, Ortel B, Stephan C, Rothaug W, Juchem R, Johannsen M, Deger S, Schnorr D, Loening S, Krell HW. The new synthetic matrix metalloproteinase inhibitor (Roche 28-2653) reduces tumor growth and prolongs survival in a prostate cancer standard rat model. Oncogene. 2002 Mar 27; 21(13):2089-96. PMID: 11960381.
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    25. Hamblin MR, Miller JL, Rizvi I, Ortel B. Degree of substitution of chlorin e6 on charged poly-L-lysine chains affects their cellular uptake, localization and phototoxicity towards macrophages and cancer cells. J Xray Sci Technol. 2002 Jan 01; 10(3):139-52. PMID: 22388044.
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    26. Alge C, Baxter RM, Doyle ME, Moor AC, Brissette JL, Ortel B. PUVA downregulates whn expression in primary mouse keratinocytes. J Photochem Photobiol B. 2001 Nov 01; 64(1):75-81. PMID: 11705733.
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    27. Hamblin MR, Miller JL, Rizvi I, Ortel B, Maytin EV, Hasan T. Pegylation of a chlorin(e6) polymer conjugate increases tumor targeting of photosensitizer. Cancer Res. 2001 Oct 01; 61(19):7155-62. PMID: 11585749.
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    28. Pogue BW, Ortel B, Chen N, Redmond RW, Hasan T. A photobiological and photophysical-based study of phototoxicity of two chlorins. Cancer Res. 2001 Jan 15; 61(2):717-24. PMID: 11212274.
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    29. Hamblin MR, Miller JL, Ortel B. Scavenger-receptor targeted photodynamic therapy. Photochem Photobiol. 2000 Oct; 72(4):533-40. PMID: 11045726.
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    30. Lein M, Koenig F, Misdraji J, McDougal WS, Jung K, Loening SA, Hasan T, Ortel B. Laser-induced hyperthermia in rat prostate cancer: role of site of tumor implantation. Urology. 2000 Jul; 56(1):167-72. PMID: 10869660.
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    31. Lein M, Jung K, Le DK, Hasan T, Ortel B, Borchert D, Winkelmann B, Schnorr D, Loenings SA. Synthetic inhibitor of matrix metalloproteinases (batimastat) reduces prostate cancer growth in an orthotopic rat model. Prostate. 2000 May 01; 43(2):77-82. PMID: 10754522.
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    32. Asawanonda P, Ortel B, Taylor CR. Temperatures reached inside stand-up ultraviolet treatment boxes. Photodermatol Photoimmunol Photomed. 1999 Oct; 15(5):179-82. PMID: 10540940.
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    33. Tanew A, Ortel B, Hönigsmann H. Half-side comparison of erythemogenic versus suberythemogenic UVA doses in oral photochemotherapy of psoriasis. J Am Acad Dermatol. 1999 Sep; 41(3 Pt 1):408-13. PMID: 10459114.
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    34. Runnels JM, Chen N, Ortel B, Kato D, Hasan T. BPD-MA-mediated photosensitization in vitro and in vivo: cellular adhesion and beta1 integrin expression in ovarian cancer cells. Br J Cancer. 1999 Jun; 80(7):946-53. PMID: 10362101.
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    35. Radakovic-Fijan S, Rappersberger K, Tanew A, Hönigsmann H, Ortel B. Ultrastructural changes in PAM cells after photodynamic treatment with delta-aminolevulinic acid-induced porphyrins or photosan. J Invest Dermatol. 1999 Mar; 112(3):264-70. PMID: 10084300.
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    36. Breier-Maly J, Ortel B, Breier F, Schmidt JB, Hönigsmann H. Generalized pustular psoriasis of pregnancy (impetigo herpetiformis). Dermatology. 1999; 198(1):61-4. PMID: 10026404.
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    37. Ortel B, Chen N, Brissette J, Dotto GP, Maytin E, Hasan T. Differentiation-specific increase in ALA-induced protoporphyrin IX accumulation in primary mouse keratinocytes. Br J Cancer. 1998 Jun; 77(11):1744-51. PMID: 9667642.
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    38. Kramell R, Miersch O, Hause B, Ortel B, Parthier B, Wasternack C. Amino acid conjugates of jasmonic acid induce jasmonate-responsive gene expression in barley (Hordeum vulgare L.) leaves. FEBS Lett. 1997 Sep 08; 414(2):197-202. PMID: 9315685.
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    39. Calzavara-Pinton PG, Szeimies RM, Ortel B, Zane C. Photodynamic therapy with systemic administration of photosensitizers in dermatology. J Photochem Photobiol B. 1996 Nov; 36(2):225-31. PMID: 9002266.
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    40. Szeimies RM, Calzavara-Pinton P, Karrer S, Ortel B, Landthaler M. Topical photodynamic therapy in dermatology. J Photochem Photobiol B. 1996 Nov; 36(2):213-9. PMID: 9002264.
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    41. Ortel B, Calzavara-Pinton PG, Szeimies RM, Hasan T. Perspectives in cutaneous photodynamic sensitization. J Photochem Photobiol B. 1996 Nov; 36(2):209-11. PMID: 9002263.
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    42. Maier H, Schemper M, Ortel B, Binder M, Tanew A, Hönigsmann H. Skin tumors in photochemotherapy for psoriasis: a single-center follow-up of 496 patients. Dermatology. 1996; 193(3):185-91. PMID: 8944338.
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    43. Perl S, Rappersberger K, Födinger D, Anegg B, Hönigsmann H, Ortel B. Bullous pemphigoid induced by PUVA therapy. Dermatology. 1996; 193(3):245-7. PMID: 8944349.
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    44. Maier H, Diem E, Gotschim A, Ortel B. [Pyoderma gangrenosum as a precursor of myeloid leukemia]. Hautarzt. 1995 Sep; 46(9):647-50. PMID: 7591771.
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    45. Fijan S, Hönigsmann H, Ortel B. Photodynamic therapy of epithelial skin tumours using delta-aminolaevulinic acid and desferrioxamine. Br J Dermatol. 1995 Aug; 133(2):282-8. PMID: 7547399.
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    46. Rünger TM, Lehmann P, Neumann NJ, Matthies C, Schauder S, Ortel B, Münzberger C, Hölzle E. [Recommendations for a photo-patch test standard series by the German speaking study group "Photopatch-Test"]. Hautarzt. 1995 Apr; 46(4):240-3. PMID: 7790188.
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    47. Reinbothe C, Ortel B, Parthier B, Reinbothe S. Cytosolic and plastid forms of 5-enolpyruvylshikimate-3-phosphate synthase in Euglena gracilis are differentially expressed during light-induced chloroplast development. Mol Gen Genet. 1994 Dec 01; 245(5):616-22. PMID: 7808412.
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    48. Iinuma S, Farshi SS, Ortel B, Hasan T. A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin. Br J Cancer. 1994 Jul; 70(1):21-8. PMID: 8018536.
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    49. Rappersberger K, Ortel B, Forstinger C, Wolff K. [Therapy of cutaneous T-cell lymphomas]. Wien Klin Wochenschr. 1994; 106(10):300-8. PMID: 8053197.
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    50. Calzavara-Pinton PG, Ortel B, Hönigsmann H, Zane C, De Panfilis G. Safety and effectiveness of an aggressive and individualized bath-PUVA regimen in the treatment of psoriasis. Dermatology. 1994; 189(3):256-9. PMID: 7949478.
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    51. Ortel B, Perl S, Kinaciyan T, Calzavara-Pinton PG, Hönigsmann H. Comparison of narrow-band (311 nm) UVB and broad-band UVA after oral or bath-water 8-methoxypsoralen in the treatment of psoriasis. J Am Acad Dermatol. 1993 Nov; 29(5 Pt 1):736-40. PMID: 8227546.
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    52. Tanew A, Ortel B, Hönigsmann H. UVA does not photoreactivate pyrimidine dimers in cultured human fibroblasts. Exp Dermatol. 1993 Aug; 2(4):161-4. PMID: 8162334.
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    53. Reinbothe S, Ortel B, Parthier B. Overproduction by gene amplification of the multifunctional arom protein confers glyphosate tolerance to a plastid-free mutant of Euglena gracilis. Mol Gen Genet. 1993 Jun; 239(3):416-24. PMID: 8391114.
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    54. Calzavara-Pinton PG, Ortel B, Carlino AM, Honigsmann H, De Panfilis G. Phototesting and phototoxic side effects in bath PUVA. J Am Acad Dermatol. 1993 Apr; 28(4):657-9. PMID: 8463475.
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    55. Ortel B. [Long-term effect of psoralens?]. Hautarzt. 1993 Apr; 44(4):249. PMID: 8482610.
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    56. Ortel B, Tanew A, Hönigsmann H. Lethal photosensitization by endogenous porphyrins of PAM cells--modification by desferrioxamine. J Photochem Photobiol B. 1993 Mar; 17(3):273-8. PMID: 8492244.
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    57. Calzavara-Pinton P, Ortel B, Carlino A, Hönigsmann H, De Panfilis G. 8-MOP vs 5-MOP. Exp Dermatol. 1992 Nov; 1(4):206. PMID: 1365321.
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    58. Calzavara-Pinton P, Ortel B, Carlino A, Honigsmann H, De Panfilis G. A reappraisal of the use of 5-methoxypsoralen in the therapy of psoriasis. Exp Dermatol. 1992 Jul; 1(1):46-51. PMID: 1344660.
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    59. Ortel B, Rappersberger K, Konrad K. Middermal elastolysis in an elderly man with evidence of elastic fiber phagocytosis. Arch Dermatol. 1992 Jan; 128(1):88-90. PMID: 1739292.
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    60. Petzelbauer P, Binder M, Nikolakis P, Ortel B, Hönigsmann H. Severe sun sensitivity and the presence of antinuclear antibodies in patients with polymorphous light eruption-like lesions. A form fruste of photosensitive lupus erythematosus? J Am Acad Dermatol. 1992 Jan; 26(1):68-74. PMID: 1732339.
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    61. Ortel B, Maytum DJ, Gange RW. Long persistence of monofunctional 8-methoxypsoralen-DNA adducts in human skin in vivo. Photochem Photobiol. 1991 Oct; 54(4):645-50. PMID: 1796119.
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    62. Brücke J, Tanew A, Ortel B, Hönigsmann H. Relative efficacy of 335 and 365 nm radiation in photochemotherapy of psoriasis. Br J Dermatol. 1991 Apr; 124(4):372-4. PMID: 2025558.
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    63. Ortel B, Gange RW, Hasan T. Investigations of a manganese-containing mimic of superoxide dismutase in riboflavin phototoxicity in human cells in vitro. J Photochem Photobiol B. 1990 Nov; 7(2-4):261-76. PMID: 1964963.
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    64. Ortel B, Gange RW. An action spectrum for the elicitation of erythema in skin persistently sensitized by photobound 8-methoxypsoralen. J Invest Dermatol. 1990 Jun; 94(6):781-5. PMID: 2355181.
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    65. Rappersberger K, Hönigsmann H, Ortel B, Tanew A, Konrad K, Wolff K. Photosensitivity and hyperpigmentation in amiodarone-treated patients: incidence, time course, and recovery. J Invest Dermatol. 1989 Aug; 93(2):201-9. PMID: 2754275.
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    66. Ortel B, Sivayathorn A, Hönigsmann H. An unusual combination of phototoxicity and Stevens-Johnson syndrome due to antimalarial therapy. Dermatologica. 1989; 178(1):39-42. PMID: 2917679.
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    67. Hönigsmann H, Tanew A, Brücke J, Ortel B. Photosensitizing compounds in the treatment of psoriasis. Ciba Found Symp. 1989; 146:159-67; discussion 167-70. PMID: 2697531.
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    68. Hönigsmann H, Ortel B. [Polymorphous photodermatosis--photobiologic diagnosis and therapy]. Z Hautkr. 1988 Aug 15; 63(8):676-8. PMID: 3263738.
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    69. Ortel B, Wechdorn D, Tanew A, Hönigsmann H. Effect of nicotinamide on the phototest reaction in polymorphous light eruption. Br J Dermatol. 1988 May; 118(5):669-73. PMID: 2969258.
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    70. Morliere P, Hönigsmann H, Averbeck D, Dardalhon M, Hüppe G, Ortel B, Santus R, Dubertret L. Phototherapeutic, photobiologic, and photosensitizing properties of khellin. J Invest Dermatol. 1988 May; 90(5):720-4. PMID: 3283251.
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    71. Ortel B, Tanew A, Hönigsmann H. Treatment of vitiligo with khellin and ultraviolet A. J Am Acad Dermatol. 1988 Apr; 18(4 Pt 1):693-701. PMID: 3270995.
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    72. Tanew A, Ortel B, Rappersberger K, Hönigsmann H. 5-Methoxypsoralen (Bergapten) for photochemotherapy. Bioavailability, phototoxicity, and clinical efficacy in psoriasis of a new drug preparation. J Am Acad Dermatol. 1988 Feb; 18(2 Pt 1):333-8. PMID: 3279089.
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    73. Ortel B, Diem E, Rappersberger K, Konrad K, Groh V. [Lymphomatoid granulomatosis]. Hautarzt. 1987 Oct; 38(10):624-8. PMID: 3679819.
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    74. Hönigsmann H, Brenner W, Tanew A, Ortel B. UV-induced unscheduled DNA synthesis in human skin: dose response, correlation with erythema, time course and split dose exposure in vivo. J Photochem Photobiol B. 1987 Sep; 1(1):33-43. PMID: 3149981.
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    75. Tanew A, Hönigsmann H, Ortel B, Zussner C, Wolff K. Nonmelanoma skin tumors in long-term photochemotherapy treatment of psoriasis. An 8-year follow-up study. J Am Acad Dermatol. 1986 Nov; 15(5 Pt 1):960-5. PMID: 3782536.
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    76. Förster O, Boltz-Nitulescu G, Holzinger C, Wiltschke C, Riedl M, Ortel B, Fellinger A, Bernheimer H. Specificity of ganglioside binding to rat macrophages. Mol Immunol. 1986 Nov; 23(11):1267-73. PMID: 3821740.
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    77. Ortel B, Tanew A, Wolff K, Hönigsmann H. Polymorphous light eruption: action spectrum and photoprotection. J Am Acad Dermatol. 1986 May; 14(5 Pt 1):748-53. PMID: 3711378.
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    78. Ortel B, Tanew A, Hönigsmann H. Vitiligo treatment. Curr Probl Dermatol. 1986; 15:265-71. PMID: 3948525.
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    79. Prskavec FH, Diem E, Klemen UM, Ortel B. [Eye changes in lymphomatoid granulomatosis]. Fortschr Ophthalmol. 1986; 83(2):238-9. PMID: 3710382.
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    80. Tanew A, Ortel B, Wolff K, Hönigsmann H. PUVA for cutaneous T-cell lymphoma. 10 years after. Curr Probl Dermatol. 1986; 15:232-7. PMID: 3485032.
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    81. Hönigsmann H, Ortel B. Khellin photochemotherapy of vitiligo. Photodermatol. 1985 Aug; 2(4):193-4. PMID: 4059075.
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    82. Boltz-Nitulescu G, Ortel B, Riedl M, Förster O. Ganglioside receptor of rat macrophages. Modulation by enzyme treatment and evidence for its protein nature. Immunology. 1984 Jan; 51(1):177-84. PMID: 6317544.
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