The University of Chicago Header Logo

Connection

Ralph Weichselbaum to Cell Line, Tumor

This is a "connection" page, showing publications Ralph Weichselbaum has written about Cell Line, Tumor.
Connection Strength

2.861
  1. Radiation-induced amphiregulin drives tumour metastasis. Nature. 2025 07; 643(8072):810-819.
    View in: PubMed
    Score: 0.141
  2. Targeting the Dendritic Cell-Secreted Immunoregulatory Cytokine CCL22 Alleviates Radioresistance. Clin Cancer Res. 2024 Oct 01; 30(19):4450-4463.
    View in: PubMed
    Score: 0.135
  3. RIG-I-Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy. Cancer Res. 2020 12 15; 80(24):5633-5641.
    View in: PubMed
    Score: 0.103
  4. Tumor-reprogrammed resident T cells resist radiation to control tumors. Nat Commun. 2019 09 02; 10(1):3959.
    View in: PubMed
    Score: 0.095
  5. Combination of radiotherapy and vaccination overcomes checkpoint blockade resistance. Oncotarget. 2016 Jul 12; 7(28):43039-43051.
    View in: PubMed
    Score: 0.077
  6. 14q32-encoded microRNAs mediate an oligometastatic phenotype. Oncotarget. 2015 Feb 28; 6(6):3540-52.
    View in: PubMed
    Score: 0.070
  7. A survivin-associated adaptive response in radiation therapy. Cancer Res. 2013 Jul 15; 73(14):4418-28.
    View in: PubMed
    Score: 0.061
  8. A manganese superoxide dismutase (SOD2)-mediated adaptive response. Radiat Res. 2013 Feb; 179(2):115-24.
    View in: PubMed
    Score: 0.060
  9. Tumor endothelial inflammation predicts clinical outcome in diverse human cancers. PLoS One. 2012; 7(10):e46104.
    View in: PubMed
    Score: 0.059
  10. MicroRNA expression characterizes oligometastasis(es). PLoS One. 2011; 6(12):e28650.
    View in: PubMed
    Score: 0.056
  11. Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation. Mol Cancer Ther. 2011 Jul; 10(7):1185-93.
    View in: PubMed
    Score: 0.054
  12. Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors. Cancer Res. 2010 Aug 01; 70(15):6277-82.
    View in: PubMed
    Score: 0.050
  13. An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer. Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18490-5.
    View in: PubMed
    Score: 0.045
  14. Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy. Cancer Gene Ther. 2009 Apr; 16(4):373-81.
    View in: PubMed
    Score: 0.045
  15. Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy. Cancer Gene Ther. 2008 Mar; 15(3):133-9.
    View in: PubMed
    Score: 0.042
  16. Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB. Int J Oncol. 2007 Dec; 31(6):1519-28.
    View in: PubMed
    Score: 0.042
  17. Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy. Clin Cancer Res. 2007 Oct 15; 13(20):6217-23.
    View in: PubMed
    Score: 0.042
  18. Tumor genotype determines susceptibility to oncolytic herpes simplex virus mutants: strategies for clinical application. Future Oncol. 2007 Oct; 3(5):545-56.
    View in: PubMed
    Score: 0.042
  19. Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding. Cancer Res. 2007 Jul 15; 67(14):6889-98.
    View in: PubMed
    Score: 0.041
  20. Engineered probiotic Bifidobacterium for tumor-targeted pancreatic cancer therapy. Sci Adv. 2026 Jul 24; 12(30):eadz1388.
    View in: PubMed
    Score: 0.038
  21. Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells. Cancer Chemother Pharmacol. 2006 Dec; 58(6):765-70.
    View in: PubMed
    Score: 0.038
  22. Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1. J Virol. 2006 Feb; 80(3):1110-20.
    View in: PubMed
    Score: 0.037
  23. Letting Biology Validate the EPR Imaging of Tumor pO2. Adv Exp Med Biol. 2026; 1498:53-58.
    View in: PubMed
    Score: 0.037
  24. NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity. Nature. 2025 09; 645(8082):1051-1059.
    View in: PubMed
    Score: 0.036
  25. Nanoscale Donor-Acceptor Covalent Organic Frameworks for Mitochondria-Targeted Sonodynamic Therapy and Antitumor Immunity. J Am Chem Soc. 2025 07 23; 147(29):25622-25634.
    View in: PubMed
    Score: 0.036
  26. A universal chimeric antigen receptor (CAR)-fragment antibody binder (FAB) split system for cancer immunotherapy. Sci Adv. 2025 Jul 04; 11(27):eadv4937.
    View in: PubMed
    Score: 0.036
  27. Transforming malignant tumors into vulnerable phenotypes via nanoscale coordination polymer mediated cell senescence and photodynamic therapy. Biomaterials. 2025 Nov; 322:123355.
    View in: PubMed
    Score: 0.035
  28. Nanoparticle-Mediated Toll-Like Receptor Activation and Dual Immune Checkpoint Downregulation for Potent Cancer Immunotherapy. ACS Nano. 2025 03 11; 19(9):8852-8866.
    View in: PubMed
    Score: 0.035
  29. Nanoscale Mixed-Ligand Metal-Organic Framework for X-ray Stimulated Cancer Therapy. J Am Chem Soc. 2024 12 04; 146(48):33149-33158.
    View in: PubMed
    Score: 0.034
  30. Bifunctional Metal-Organic Framework Synergistically Enhances Radiotherapy and Activates STING for Potent Cancer Radio-Immunotherapy. Angew Chem Int Ed Engl. 2025 Jan 27; 64(5):e202417027.
    View in: PubMed
    Score: 0.034
  31. Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma. Cancer Res. 2004 Sep 15; 64(18):6381-4.
    View in: PubMed
    Score: 0.034
  32. Digitonin-Loaded Nanoscale Metal-Organic Framework for Mitochondria-Targeted Radiotherapy-Radiodynamic Therapy and Disulfidptosis. Adv Mater. 2025 Dec; 37(52):e2405494.
    View in: PubMed
    Score: 0.034
  33. Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity. Mol Cancer Ther. 2004 Sep; 3(9):1167-75.
    View in: PubMed
    Score: 0.034
  34. STING activation disrupts tumor vasculature to overcome the EPR limitation and increase drug deposition. Sci Adv. 2024 07 19; 10(29):eado0082.
    View in: PubMed
    Score: 0.033
  35. Mitochondria-Targeted Multifunctional Nanoparticles Combine Cuproptosis and Programmed Cell Death-1 Downregulation for Cancer Immunotherapy. Adv Sci (Weinh). 2024 09; 11(35):e2403520.
    View in: PubMed
    Score: 0.033
  36. Radiotherapy Enhances Metastasis Through Immune Suppression by Inducing PD-L1 and MDSC in Distal Sites. Clin Cancer Res. 2024 May 01; 30(9):1945-1958.
    View in: PubMed
    Score: 0.033
  37. Nanoparticles Synergize Ferroptosis and Cuproptosis to Potentiate Cancer Immunotherapy. Adv Sci (Weinh). 2024 06; 11(23):e2310309.
    View in: PubMed
    Score: 0.033
  38. Immunogenic Bifunctional Nanoparticle Suppresses Programmed Cell Death-Ligand 1 in Cancer and Dendritic Cells to Enhance Adaptive Immunity and Chemo-Immunotherapy. ACS Nano. 2024 02 13; 18(6):5152-5166.
    View in: PubMed
    Score: 0.032
  39. Nanoscale Covalent Organic Framework with Staggered Stacking of Phthalocyanines for Mitochondria-Targeted Photodynamic Therapy. J Am Chem Soc. 2024 01 10; 146(1):849-857.
    View in: PubMed
    Score: 0.032
  40. Nanoscale Metal-Organic Framework with an X-ray Triggerable Prodrug for Synergistic Radiotherapy and Chemotherapy. J Am Chem Soc. 2023 08 30; 145(34):18698-18704.
    View in: PubMed
    Score: 0.031
  41. Tumor-Activatable Nanoparticles Target Low-Density Lipoprotein Receptor to Enhance Drug Delivery and Antitumor Efficacy. Adv Sci (Weinh). 2022 08; 9(24):e2201614.
    View in: PubMed
    Score: 0.029
  42. All-trans retinoic acid overcomes solid tumor radioresistance by inducing inflammatory macrophages. Sci Immunol. 2021 06 15; 6(60).
    View in: PubMed
    Score: 0.027
  43. The relationship between expression of PD-L1 and HIF-1a in glioma cells under hypoxia. J Hematol Oncol. 2021 06 12; 14(1):92.
    View in: PubMed
    Score: 0.027
  44. Sunitinib-Loaded Chondroitin Sulfate Hydrogels as a Novel Drug-Delivery Mechanism for the Treatment of Pancreatic Neuroendocrine Tumors. Ann Surg Oncol. 2021 Dec; 28(13):8532-8543.
    View in: PubMed
    Score: 0.027
  45. CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma. Sci Rep. 2021 03 11; 11(1):5665.
    View in: PubMed
    Score: 0.026
  46. The Change of Soluble Programmed Cell Death-Ligand 1 in Glioma Patients Receiving Radiotherapy and Its Impact on Clinical Outcomes. Front Immunol. 2020; 11:580335.
    View in: PubMed
    Score: 0.026
  47. p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability. Nat Commun. 2020 10 06; 11(1):5007.
    View in: PubMed
    Score: 0.026
  48. Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling. J Exp Med. 2020 05 04; 217(5).
    View in: PubMed
    Score: 0.025
  49. Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors. Nat Commun. 2019 04 23; 10(1):1899.
    View in: PubMed
    Score: 0.023
  50. Temozolomide Treatment Induces lncRNA MALAT1 in an NF-?B and p53 Codependent Manner in Glioblastoma. Cancer Res. 2019 05 15; 79(10):2536-2548.
    View in: PubMed
    Score: 0.023
  51. Oxygen-Guided Radiation Therapy. Int J Radiat Oncol Biol Phys. 2019 03 15; 103(4):977-984.
    View in: PubMed
    Score: 0.023
  52. BCL3 expression promotes resistance to alkylating chemotherapy in gliomas. Sci Transl Med. 2018 07 04; 10(448).
    View in: PubMed
    Score: 0.022
  53. Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy. Nat Commun. 2018 06 15; 9(1):2351.
    View in: PubMed
    Score: 0.022
  54. Low-dose X-ray radiotherapy-radiodynamic therapy via nanoscale metal-organic frameworks enhances checkpoint blockade immunotherapy. Nat Biomed Eng. 2018 08; 2(8):600-610.
    View in: PubMed
    Score: 0.022
  55. Host STING-dependent MDSC mobilization drives extrinsic radiation resistance. Nat Commun. 2017 11 23; 8(1):1736.
    View in: PubMed
    Score: 0.021
  56. Tumour ischaemia by interferon-? resembles physiological blood vessel regression. Nature. 2017 05 04; 545(7652):98-102.
    View in: PubMed
    Score: 0.020
  57. CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response. Cell Rep. 2017 03 07; 18(10):2373-2386.
    View in: PubMed
    Score: 0.020
  58. Transfer of Allogeneic CD4+ T Cells Rescues CD8+ T Cells in Anti-PD-L1-Resistant Tumors Leading to Tumor Eradication. Cancer Immunol Res. 2017 02; 5(2):127-136.
    View in: PubMed
    Score: 0.020
  59. Photodynamic Therapy Mediated by Nontoxic Core-Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer. J Am Chem Soc. 2016 12 28; 138(51):16686-16695.
    View in: PubMed
    Score: 0.020
  60. Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy. Nat Commun. 2016 08 17; 7:12499.
    View in: PubMed
    Score: 0.019
  61. Very low doses of ionizing radiation and redox associated modifiers affect survivin-associated changes in radiation sensitivity. Free Radic Biol Med. 2016 10; 99:110-119.
    View in: PubMed
    Score: 0.019
  62. Tumor-associated fibroblasts predominantly come from local and not circulating precursors. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):7551-6.
    View in: PubMed
    Score: 0.019
  63. Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs. Oncotarget. 2016 May 03; 7(18):26496-515.
    View in: PubMed
    Score: 0.019
  64. Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation. Clin Cancer Res. 2016 06 01; 22(11):2734-43.
    View in: PubMed
    Score: 0.018
  65. Imaging of tumor clones with differential liver colonization. Sci Rep. 2015 Jun 22; 5:10946.
    View in: PubMed
    Score: 0.018
  66. Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome. Br J Cancer. 2015 Jul 14; 113(2):327-35.
    View in: PubMed
    Score: 0.018
  67. Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide. Cancer Res. 2015 May 15; 75(10):2039-48.
    View in: PubMed
    Score: 0.018
  68. RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells. Nucleic Acids Res. 2015 Mar 31; 43(6):3180-96.
    View in: PubMed
    Score: 0.017
  69. MUC1-C activates the TAK1 inflammatory pathway in colon cancer. Oncogene. 2015 Oct 01; 34(40):5187-97.
    View in: PubMed
    Score: 0.017
  70. Poly (ADP-ribose) polymerase inhibitor efficacy in head and neck cancer. Oral Oncol. 2014 Sep; 50(9):825-31.
    View in: PubMed
    Score: 0.017
  71. The RAD51-stimulatory compound RS-1 can exploit the RAD51 overexpression that exists in cancer cells and tumors. Cancer Res. 2014 Jul 01; 74(13):3546-55.
    View in: PubMed
    Score: 0.016
  72. DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy. Sci Transl Med. 2014 Mar 26; 6(229):229ra42.
    View in: PubMed
    Score: 0.016
  73. Targeting the tumor microenvironment with interferon-ß bridges innate and adaptive immune responses. Cancer Cell. 2014 Jan 13; 25(1):37-48.
    View in: PubMed
    Score: 0.016
  74. Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. J Clin Invest. 2014 Feb; 124(2):687-95.
    View in: PubMed
    Score: 0.016
  75. Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma. Nanomedicine. 2014 Jan; 10(1):149-57.
    View in: PubMed
    Score: 0.016
  76. Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells. PLoS One. 2012; 7(7):e39432.
    View in: PubMed
    Score: 0.015
  77. Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer. Oncol Rep. 2012 May; 27(5):1625-9.
    View in: PubMed
    Score: 0.014
  78. p50 (NF-?B1) is an effector protein in the cytotoxic response to DNA methylation damage. Mol Cell. 2011 Dec 09; 44(5):785-96.
    View in: PubMed
    Score: 0.014
  79. SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine. Free Radic Biol Med. 2011 Nov 15; 51(10):1918-25.
    View in: PubMed
    Score: 0.014
  80. Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes. Cancer Immun. 2011 Jun 30; 11:2.
    View in: PubMed
    Score: 0.014
  81. Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis. PLoS Comput Biol. 2010 Apr 01; 6(4):e1000730.
    View in: PubMed
    Score: 0.012
  82. Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. Oncogene. 2010 Feb 11; 29(6):920-9.
    View in: PubMed
    Score: 0.012
  83. STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect. BMC Med. 2009 Nov 05; 7:68.
    View in: PubMed
    Score: 0.012
  84. Characterization of response to radiation mediated gene therapy by means of multimodality imaging. Magn Reson Med. 2009 Aug; 62(2):348-56.
    View in: PubMed
    Score: 0.012
  85. Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling. Int J Radiat Biol. 2009 May; 85(5):421-31.
    View in: PubMed
    Score: 0.012
  86. Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. J Exp Med. 2007 Jan 22; 204(1):49-55.
    View in: PubMed
    Score: 0.010
  87. Glioblastoma cells block radiation-induced programmed cell death of endothelial cells. FEBS Lett. 2004 May 07; 565(1-3):167-70.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.