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Dorothy Hanck to Sodium Channels

This is a "connection" page, showing publications Dorothy Hanck has written about Sodium Channels.

 
Connection Strength
 
 
 
8.281
 
  1. Sheets MF, Fozzard HA, Hanck DA. Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels. Biophys J. 2015 Dec 01; 109(11):2277-86.
    View in: PubMed
    Score: 0.617
  2. Sheets MF, Chen T, Hanck DA. Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel. Pflugers Arch. 2011 Jan; 461(1):91-7.
    View in: PubMed
    Score: 0.434
  3. Sheets MF, Fozzard HA, Lipkind GM, Hanck DA. Sodium channel molecular conformations and antiarrhythmic drug affinity. Trends Cardiovasc Med. 2010 Jan; 20(1):16-21.
    View in: PubMed
    Score: 0.410
  4. Hanck DA, Nikitina E, McNulty MM, Fozzard HA, Lipkind GM, Sheets MF. Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity. Circ Res. 2009 Aug 28; 105(5):492-9.
    View in: PubMed
    Score: 0.398
  5. Edgerton GB, Blumenthal KM, Hanck DA. Evidence for multiple effects of ProTxII on activation gating in Na(V)1.5. Toxicon. 2008 Sep 01; 52(3):489-500.
    View in: PubMed
    Score: 0.370
  6. Hanck DA, Sheets MF. Site-3 toxins and cardiac sodium channels. Toxicon. 2007 Feb; 49(2):181-93.
    View in: PubMed
    Score: 0.327
  7. McNulty MM, Kyle JW, Lipkind GM, Hanck DA. An inner pore residue (Asn406) in the Nav1.5 channel controls slow inactivation and enhances mibefradil block to T-type Ca2+ channel levels. Mol Pharmacol. 2006 Nov; 70(5):1514-23.
    View in: PubMed
    Score: 0.323
  8. Sheets MF, Hanck DA. Charge immobilization of the voltage sensor in domain IV is independent of sodium current inactivation. J Physiol. 2005 Feb 15; 563(Pt 1):83-93.
    View in: PubMed
    Score: 0.288
  9. McNulty MM, Hanck DA. State-dependent mibefradil block of Na+ channels. Mol Pharmacol. 2004 Dec; 66(6):1652-61.
    View in: PubMed
    Score: 0.288
  10. Sheets MF, Hanck DA. Molecular action of lidocaine on the voltage sensors of sodium channels. J Gen Physiol. 2003 Feb; 121(2):163-75.
    View in: PubMed
    Score: 0.254
  11. Sheets MF, Hanck DA. The outermost lysine in the S4 of domain III contributes little to the gating charge in sodium channels. Biophys J. 2002 Jun; 82(6):3048-55.
    View in: PubMed
    Score: 0.242
  12. Martin RL, Pittendrigh B, Liu J, Reenan R, ffrench-Constant R, Hanck DA. Point mutations in domain III of a Drosophila neuronal Na channel confer resistance to allethrin. Insect Biochem Mol Biol. 2000 Nov; 30(11):1051-9.
    View in: PubMed
    Score: 0.217
  13. Sheets MF, Kyle JW, Hanck DA. The role of the putative inactivation lid in sodium channel gating current immobilization. J Gen Physiol. 2000 May; 115(5):609-20.
    View in: PubMed
    Score: 0.210
  14. Hanck DA, Makielski JC, Sheets MF. Lidocaine alters activation gating of cardiac Na channels. Pflugers Arch. 2000 Apr; 439(6):814-21.
    View in: PubMed
    Score: 0.208
  15. Sheets MF, Kyle JW, Kallen RG, Hanck DA. The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4. Biophys J. 1999 Aug; 77(2):747-57.
    View in: PubMed
    Score: 0.199
  16. Sheets MF, Hanck DA. Gating of skeletal and cardiac muscle sodium channels in mammalian cells. J Physiol. 1999 Jan 15; 514 ( Pt 2):425-36.
    View in: PubMed
    Score: 0.192
  17. Hanck D. Heartthrobs. Science. 1998 Feb 13; 279(5353):1004.
    View in: PubMed
    Score: 0.180
  18. Benzinger GR, Kyle JW, Blumenthal KM, Hanck DA. A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B. J Biol Chem. 1998 Jan 02; 273(1):80-4.
    View in: PubMed
    Score: 0.178
  19. Millonas MM, Hanck DA. Nonequilibrium response spectroscopy of voltage-sensitive ion channel gating. Biophys J. 1998 Jan; 74(1):210-29.
    View in: PubMed
    Score: 0.178
  20. Benzinger GR, Drum CL, Chen LQ, Kallen RG, Hanck DA, Hanck D. Differences in the binding sites of two site-3 sodium channel toxins. Pflugers Arch. 1997 Nov; 434(6):742-9.
    View in: PubMed
    Score: 0.176
  21. Sheets MF, Kyle JW, Krueger S, Hanck DA. Optimization of a mammalian expression system for the measurement of sodium channel gating currents. Am J Physiol. 1996 Sep; 271(3 Pt 1):C1001-6.
    View in: PubMed
    Score: 0.163
  22. Fozzard HA, Hanck DA. Structure and function of voltage-dependent sodium channels: comparison of brain II and cardiac isoforms. Physiol Rev. 1996 Jul; 76(3):887-926.
    View in: PubMed
    Score: 0.161
  23. Zeng D, Kyle JW, Martin RL, Ambler KS, Hanck DA. Cardiac sodium channels expressed in a peripheral neurotumor-derived cell line, RT4-B8. Am J Physiol. 1996 May; 270(5 Pt 1):C1522-31.
    View in: PubMed
    Score: 0.159
  24. Hanck DA, Sheets MF. Modification of inactivation in cardiac sodium channels: ionic current studies with Anthopleurin-A toxin. J Gen Physiol. 1995 Oct; 106(4):601-16.
    View in: PubMed
    Score: 0.153
  25. Sheets MF, Hanck DA. Voltage-dependent open-state inactivation of cardiac sodium channels: gating current studies with Anthopleurin-A toxin. J Gen Physiol. 1995 Oct; 106(4):617-40.
    View in: PubMed
    Score: 0.153
  26. Ono K, Fozzard HA, Hanck DA. A direct effect of forskolin on sodium channel bursting. Pflugers Arch. 1995 Feb; 429(4):561-9.
    View in: PubMed
    Score: 0.146
  27. Hanck DA, Makielski JC, Sheets MF. Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. J Gen Physiol. 1994 Jan; 103(1):19-43.
    View in: PubMed
    Score: 0.135
  28. Sheets MF, Hanck DA. Modification of sodium channel inactivation by alpha-chymotrypsin in canine cardiac Purkinje cells. J Cardiovasc Electrophysiol. 1993 Dec; 4(6):686-94.
    View in: PubMed
    Score: 0.134
  29. Ono K, Fozzard HA, Hanck DA. Mechanism of cAMP-dependent modulation of cardiac sodium channel current kinetics. Circ Res. 1993 Apr; 72(4):807-15.
    View in: PubMed
    Score: 0.128
  30. Hanck DA, Sheets MF. Extracellular divalent and trivalent cation effects on sodium current kinetics in single canine cardiac Purkinje cells. J Physiol. 1992 Aug; 454:267-98.
    View in: PubMed
    Score: 0.122
  31. Sheets MF, Hanck DA. Mechanisms of extracellular divalent and trivalent cation block of the sodium current in canine cardiac Purkinje cells. J Physiol. 1992 Aug; 454:299-320.
    View in: PubMed
    Score: 0.122
  32. el-Sherif N, Fozzard HA, Hanck DA. Dose-dependent modulation of the cardiac sodium channel by sea anemone toxin ATXII. Circ Res. 1992 Feb; 70(2):285-301.
    View in: PubMed
    Score: 0.118
  33. Sheets MF, Hanck DA. Atrionatriuretic peptide and calcium-conducting sodium channels. Science. 1991 Apr 19; 252(5004):449-52.
    View in: PubMed
    Score: 0.112
  34. Makielski JC, Alpert LA, Hanck DA. Two components of use-dependent block of sodium current by lidocaine in voltage clamped cardiac Purkinje cells. J Mol Cell Cardiol. 1991 Feb; 23 Suppl 1:95-102.
    View in: PubMed
    Score: 0.110
  35. Hanck DA, Sheets MF, Fozzard HA. Gating currents associated with Na channels in canine cardiac Purkinje cells. J Gen Physiol. 1990 Mar; 95(3):439-57.
    View in: PubMed
    Score: 0.104
  36. Sheets MF, Hanck DA. Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels. J Physiol. 2007 Jul 01; 582(Pt 1):317-34.
    View in: PubMed
    Score: 0.085
  37. Khan A, Kyle JW, Hanck DA, Lipkind GM, Fozzard HA. Isoform-dependent interaction of voltage-gated sodium channels with protons. J Physiol. 2006 Oct 15; 576(Pt 2):493-501.
    View in: PubMed
    Score: 0.081
  38. Sunami A, Tracey A, Glaaser IW, Lipkind GM, Hanck DA, Fozzard HA. Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na+ channel to methanethiosulfonate reagents. J Physiol. 2004 Dec 01; 561(Pt 2):403-13.
    View in: PubMed
    Score: 0.071
  39. Seibert AL, Liu J, Hanck DA, Blumenthal KM. Role of Asn-16 and Ser-19 in anthopleurin B binding. Implications for the electrostatic nature of Na(V) site 3. Biochemistry. 2004 Jun 08; 43(22):7082-9.
    View in: PubMed
    Score: 0.070
  40. Richard Benzinger G, Tonkovich GS, Hanck DA. Augmentation of recovery from inactivation by site-3 Na channel toxins. A single-channel and whole-cell study of persistent currents. J Gen Physiol. 1999 Feb; 113(2):333-46.
    View in: PubMed
    Score: 0.048
  41. Kelso GJ, Drum CL, Hanck DA, Blumenthal KM. Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel. Biochemistry. 1996 Nov 12; 35(45):14157-64.
    View in: PubMed
    Score: 0.041
  42. Dias-Kadambi BL, Drum CL, Hanck DA, Blumenthal KM. Leucine 18, a hydrophobic residue essential for high affinity binding of anthopleurin B to the voltage-sensitive sodium channel. J Biol Chem. 1996 Apr 19; 271(16):9422-8.
    View in: PubMed
    Score: 0.040
  43. Khera PK, Benzinger GR, Lipkind G, Drum CL, Hanck DA, Blumenthal KM. Multiple cationic residues of anthopleurin B that determine high affinity and channel isoform discrimination. Biochemistry. 1995 Jul 11; 34(27):8533-41.
    View in: PubMed
    Score: 0.038
  44. Hanck DA, Sheets MF. Time-dependent changes in kinetics of Na+ current in single canine cardiac Purkinje cells. Am J Physiol. 1992 Apr; 262(4 Pt 2):H1197-207.
    View in: PubMed
    Score: 0.030
  45. Scanley BE, Hanck DA, Chay T, Fozzard HA. Kinetic analysis of single sodium channels from canine cardiac Purkinje cells. J Gen Physiol. 1990 Mar; 95(3):411-37.
    View in: PubMed
    Score: 0.026
  46. McNulty MM, Edgerton GB, Shah RD, Hanck DA, Fozzard HA, Lipkind GM. Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels. J Physiol. 2007 Jun 01; 581(Pt 2):741-55.
    View in: PubMed
    Score: 0.021
  47. Seibert AL, Liu J, Hanck DA, Blumenthal KM. Arg-14 loop of site 3 anemone toxins: effects of glycine replacement on toxin affinity. Biochemistry. 2003 Dec 16; 42(49):14515-21.
    View in: PubMed
    Score: 0.017
  48. Alpert LA, Fozzard HA, Hanck DA, Makielski JC. Is there a second external lidocaine binding site on mammalian cardiac cells? Am J Physiol. 1989 Jul; 257(1 Pt 2):H79-84.
    View in: PubMed
    Score: 0.006
Connection Strength

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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.