Loading...
The University of Chicago Header Logo
Keywords
Last Name
Institution

Connection

David R. Kovar to Actins

This is a "connection" page, showing publications David R. Kovar has written about Actins.

 
Connection Strength
 
 
 
11.353
 
  1. Yde SE, Kadzik RS, Kovar DR. Stir it up: The role of actin in mitochondrial mixing during mitosis. Dev Cell. 2021 04 19; 56(8):1080-1082.
    View in: PubMed
    Score: 0.692
  2. Kadzik RS, Homa KE, Kovar DR. F-Actin Cytoskeleton Network Self-Organization Through Competition and Cooperation. Annu Rev Cell Dev Biol. 2020 10 06; 36:35-60.
    View in: PubMed
    Score: 0.667
  3. Harker AJ, Katkar HH, Bidone TC, Aydin F, Voth GA, Applewhite DA, Kovar DR. Ena/VASP processive elongation is modulated by avidity on actin filaments bundled by the filopodia cross-linker fascin. Mol Biol Cell. 2019 03 21; 30(7):851-862.
    View in: PubMed
    Score: 0.591
  4. Suarez C, McCall PM, Gardel ML, Kovar DR. When Is "Enough" Enough? Cell Syst. 2017 05 24; 4(5):480-482.
    View in: PubMed
    Score: 0.528
  5. Burke TA, Harker AJ, Dominguez R, Kovar DR. The bacterial virulence factors VopL and VopF nucleate actin from the pointed end. J Cell Biol. 2017 05 01; 216(5):1267-1276.
    View in: PubMed
    Score: 0.523
  6. Li Y, Christensen JR, Homa KE, Hocky GM, Fok A, Sees JA, Voth GA, Kovar DR. The F-actin bundler a-actinin Ain1 is tailored for ring assembly and constriction during cytokinesis in fission yeast. Mol Biol Cell. 2016 06 01; 27(11):1821-33.
    View in: PubMed
    Score: 0.489
  7. Suarez C, Carroll RT, Burke TA, Christensen JR, Bestul AJ, Sees JA, James ML, Sirotkin V, Kovar DR. Profilin regulates F-actin network homeostasis by favoring formin over Arp2/3 complex. Dev Cell. 2015 Jan 12; 32(1):43-53.
    View in: PubMed
    Score: 0.447
  8. Bestul AJ, Christensen JR, Grzegorzewska AP, Burke TA, Sees JA, Carroll RT, Sirotkin V, Keenan RJ, Kovar DR. Fission yeast profilin is tailored to facilitate actin assembly by the cytokinesis formin Cdc12. Mol Biol Cell. 2015 Jan 15; 26(2):283-93.
    View in: PubMed
    Score: 0.443
  9. Winkelman JD, Bilancia CG, Peifer M, Kovar DR. Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with Fascin. Proc Natl Acad Sci U S A. 2014 Mar 18; 111(11):4121-6.
    View in: PubMed
    Score: 0.422
  10. Burke TA, Christensen JR, Barone E, Suarez C, Sirotkin V, Kovar DR. Homeostatic actin cytoskeleton networks are regulated by assembly factor competition for monomers. Curr Biol. 2014 Mar 03; 24(5):579-85.
    View in: PubMed
    Score: 0.422
  11. Scott BJ, Neidt EM, Kovar DR. The functionally distinct fission yeast formins have specific actin-assembly properties. Mol Biol Cell. 2011 Oct; 22(20):3826-39.
    View in: PubMed
    Score: 0.355
  12. Kovar DR, Sirotkin V, Lord M. Three's company: the fission yeast actin cytoskeleton. Trends Cell Biol. 2011 Mar; 21(3):177-87.
    View in: PubMed
    Score: 0.338
  13. Rizvi SA, Neidt EM, Cui J, Feiger Z, Skau CT, Gardel ML, Kozmin SA, Kovar DR. Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly. Chem Biol. 2009 Nov 25; 16(11):1158-68.
    View in: PubMed
    Score: 0.314
  14. Kovar DR. Intracellular motility: myosin and tropomyosin in actin cable flow. Curr Biol. 2007 Apr 03; 17(7):R244-7.
    View in: PubMed
    Score: 0.262
  15. Kovar DR. Arp2/3 ATP hydrolysis: to branch or to debranch? Nat Cell Biol. 2006 Aug; 8(8):783-5.
    View in: PubMed
    Score: 0.250
  16. Kovar DR, Harris ES, Mahaffy R, Higgs HN, Pollard TD. Control of the assembly of ATP- and ADP-actin by formins and profilin. Cell. 2006 Jan 27; 124(2):423-35.
    View in: PubMed
    Score: 0.241
  17. Kovar DR. Molecular details of formin-mediated actin assembly. Curr Opin Cell Biol. 2006 Feb; 18(1):11-7.
    View in: PubMed
    Score: 0.239
  18. Kovar DR, Pollard TD. Progressing actin: Formin as a processive elongation machine. Nat Cell Biol. 2004 Dec; 6(12):1158-9.
    View in: PubMed
    Score: 0.222
  19. Kovar DR, Pollard TD. Insertional assembly of actin filament barbed ends in association with formins produces piconewton forces. Proc Natl Acad Sci U S A. 2004 Oct 12; 101(41):14725-30.
    View in: PubMed
    Score: 0.219
  20. Rosenbloom AD, Kovar EW, Kovar DR, Loew LM, Pollard TD. Mechanism of actin filament nucleation. Biophys J. 2021 10 19; 120(20):4399-4417.
    View in: PubMed
    Score: 0.178
  21. Homa KE, Zsolnay V, Anderson CA, O'Connell ME, Neidt EM, Voth GA, Bidone TC, Kovar DR. Formin Cdc12's specific actin assembly properties are tailored for cytokinesis in fission yeast. Biophys J. 2021 08 03; 120(15):2984-2997.
    View in: PubMed
    Score: 0.176
  22. Christensen JR, Craig EW, Glista MJ, Mueller DM, Li Y, Sees JA, Huang S, Suarez C, Mets LJ, Kovar DR, Avasthi P. Chlamydomonas reinhardtii formin FOR1 and profilin PRF1 are optimized for acute rapid actin filament assembly. Mol Biol Cell. 2019 12 15; 30(26):3123-3135.
    View in: PubMed
    Score: 0.156
  23. Freedman SL, Suarez C, Winkelman JD, Kovar DR, Voth GA, Dinner AR, Hocky GM. Mechanical and kinetic factors drive sorting of F-actin cross-linkers on bundles. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16192-16197.
    View in: PubMed
    Score: 0.153
  24. Christensen JR, Homa KE, Morganthaler AN, Brown RR, Suarez C, Harker AJ, O'Connell ME, Kovar DR. Cooperation between tropomyosin and a-actinin inhibits fimbrin association with actin filament networks in fission yeast. Elife. 2019 06 10; 8.
    View in: PubMed
    Score: 0.152
  25. Zimmermann D, Kovar DR. Feeling the force: formin's role in mechanotransduction. Curr Opin Cell Biol. 2019 02; 56:130-140.
    View in: PubMed
    Score: 0.148
  26. Kudryashova E, Heisler DB, Williams B, Harker AJ, Shafer K, Quinlan ME, Kovar DR, Vavylonis D, Kudryashov DS. Actin Cross-Linking Toxin Is a Universal Inhibitor of Tandem-Organized and Oligomeric G-Actin Binding Proteins. Curr Biol. 2018 05 21; 28(10):1536-1547.e9.
    View in: PubMed
    Score: 0.141
  27. McCall PM, Srivastava S, Perry SL, Kovar DR, Gardel ML, Tirrell MV. Partitioning and Enhanced Self-Assembly of Actin in Polypeptide Coacervates. Biophys J. 2018 04 10; 114(7):1636-1645.
    View in: PubMed
    Score: 0.140
  28. Suarez C, Kovar DR. Internetwork competition for monomers governs actin cytoskeleton organization. Nat Rev Mol Cell Biol. 2016 12; 17(12):799-810.
    View in: PubMed
    Score: 0.126
  29. Zimmermann D, Morganthaler AN, Kovar DR, Suarez C. In Vitro Biochemical Characterization of Cytokinesis Actin-Binding Proteins. Methods Mol Biol. 2016; 1369:151-79.
    View in: PubMed
    Score: 0.120
  30. Heisler DB, Kudryashova E, Grinevich DO, Suarez C, Winkelman JD, Birukov KG, Kotha SR, Parinandi NL, Vavylonis D, Kovar DR, Kudryashov DS. ACTIN-DIRECTED TOXIN. ACD toxin-produced actin oligomers poison formin-controlled actin polymerization. Science. 2015 Jul 31; 349(6247):535-9.
    View in: PubMed
    Score: 0.116
  31. Zimmermann D, Santos A, Kovar DR, Rock RS. Actin age orchestrates myosin-5 and myosin-6 run lengths. Curr Biol. 2015 Aug 03; 25(15):2057-62.
    View in: PubMed
    Score: 0.116
  32. Rotty JD, Wu C, Haynes EM, Suarez C, Winkelman JD, Johnson HE, Haugh JM, Kovar DR, Bear JE. Profilin-1 serves as a gatekeeper for actin assembly by Arp2/3-dependent and -independent pathways. Dev Cell. 2015 Jan 12; 32(1):54-67.
    View in: PubMed
    Score: 0.112
  33. Bilancia CG, Winkelman JD, Tsygankov D, Nowotarski SH, Sees JA, Comber K, Evans I, Lakhani V, Wood W, Elston TC, Kovar DR, Peifer M. Enabled negatively regulates diaphanous-driven actin dynamics in vitro and in vivo. Dev Cell. 2014 Feb 24; 28(4):394-408.
    View in: PubMed
    Score: 0.105
  34. Bohnert KA, Willet AH, Kovar DR, Gould KL. Formin-based control of the actin cytoskeleton during cytokinesis. Biochem Soc Trans. 2013 Dec; 41(6):1750-4.
    View in: PubMed
    Score: 0.104
  35. Madasu Y, Suarez C, Kast DJ, Kovar DR, Dominguez R. Rickettsia Sca2 has evolved formin-like activity through a different molecular mechanism. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):E2677-86.
    View in: PubMed
    Score: 0.101
  36. Falzone TT, Oakes PW, Sees J, Kovar DR, Gardel ML. Actin assembly factors regulate the gelation kinetics and architecture of F-actin networks. Biophys J. 2013 Apr 16; 104(8):1709-19.
    View in: PubMed
    Score: 0.099
  37. Falzone TT, Lenz M, Kovar DR, Gardel ML. Assembly kinetics determine the architecture of a-actinin crosslinked F-actin networks. Nat Commun. 2012 May 29; 3:861.
    View in: PubMed
    Score: 0.093
  38. Wong W, Skau CT, Marapana DS, Hanssen E, Taylor NL, Riglar DT, Zuccala ES, Angrisano F, Lewis H, Catimel B, Clarke OB, Kershaw NJ, Perugini MA, Kovar DR, Gulbis JM, Baum J. Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1. Proc Natl Acad Sci U S A. 2011 Jun 14; 108(24):9869-74.
    View in: PubMed
    Score: 0.087
  39. Haglund CM, Choe JE, Skau CT, Kovar DR, Welch MD. Rickettsia Sca2 is a bacterial formin-like mediator of actin-based motility. Nat Cell Biol. 2010 Nov; 12(11):1057-63.
    View in: PubMed
    Score: 0.084
  40. Rizvi SA, Liu S, Chen Z, Skau C, Pytynia M, Kovar DR, Chmura SJ, Kozmin SA. Rationally simplified bistramide analog reversibly targets actin polymerization and inhibits cancer progression in vitro and in vivo. J Am Chem Soc. 2010 Jun 02; 132(21):7288-90.
    View in: PubMed
    Score: 0.081
  41. Skau CT, Neidt EM, Kovar DR. Role of tropomyosin in formin-mediated contractile ring assembly in fission yeast. Mol Biol Cell. 2009 Apr; 20(8):2160-73.
    View in: PubMed
    Score: 0.075
  42. Moseley JB, Okada K, Balcer HI, Kovar DR, Pollard TD, Goode BL. Twinfilin is an actin-filament-severing protein and promotes rapid turnover of actin structures in vivo. J Cell Sci. 2006 Apr 15; 119(Pt 8):1547-57.
    View in: PubMed
    Score: 0.061
  43. Vavylonis D, Kovar DR, O'Shaughnessy B, Pollard TD. Model of formin-associated actin filament elongation. Mol Cell. 2006 Feb 17; 21(4):455-66.
    View in: PubMed
    Score: 0.061
  44. Kovar DR, Wu JQ, Pollard TD. Profilin-mediated competition between capping protein and formin Cdc12p during cytokinesis in fission yeast. Mol Biol Cell. 2005 May; 16(5):2313-24.
    View in: PubMed
    Score: 0.057
  45. Preuss ML, Kovar DR, Lee YR, Staiger CJ, Delmer DP, Liu B. A plant-specific kinesin binds to actin microfilaments and interacts with cortical microtubules in cotton fibers. Plant Physiol. 2004 Dec; 136(4):3945-55.
    View in: PubMed
    Score: 0.055
  46. Klein MG, Shi W, Ramagopal U, Tseng Y, Wirtz D, Kovar DR, Staiger CJ, Almo SC. Structure of the actin crosslinking core of fimbrin. Structure. 2004 Jun; 12(6):999-1013.
    View in: PubMed
    Score: 0.054
  47. Huang S, Blanchoin L, Kovar DR, Staiger CJ. Arabidopsis capping protein (AtCP) is a heterodimer that regulates assembly at the barbed ends of actin filaments. J Biol Chem. 2003 Nov 07; 278(45):44832-42.
    View in: PubMed
    Score: 0.051
  48. Snowman BN, Kovar DR, Shevchenko G, Franklin-Tong VE, Staiger CJ. Signal-mediated depolymerization of actin in pollen during the self-incompatibility response. Plant Cell. 2002 Oct; 14(10):2613-26.
    View in: PubMed
    Score: 0.048
  49. Billault-Chaumartin I, Michon L, Anderson CA, Yde SE, Suarez C, Iwaszkiewicz J, Zoete V, Kovar DR, Martin SG. Actin assembly requirements of the formin Fus1 to build the fusion focus. J Cell Sci. 2022 07 01; 135(13).
    View in: PubMed
    Score: 0.047
  50. Kovar DR, Yang P, Sale WS, Drobak BK, Staiger CJ. Chlamydomonas reinhardtii produces a profilin with unusual biochemical properties. J Cell Sci. 2001 Dec; 114(Pt 23):4293-305.
    View in: PubMed
    Score: 0.045
  51. Kovar DR, Drøbak BK, Collings DA, Staiger CJ. The characterization of ligand-specific maize (Zea mays) profilin mutants. Biochem J. 2001 Aug 15; 358(Pt 1):49-57.
    View in: PubMed
    Score: 0.044
  52. Kovar DR, Gibbon BC, McCurdy DW, Staiger CJ. Fluorescently-labeled fimbrin decorates a dynamic actin filament network in live plant cells. Planta. 2001 Jul; 213(3):390-5.
    View in: PubMed
    Score: 0.044
  53. Anderson CA, Kovar DR, Gardel ML, Winkelman JD. LIM domain proteins in cell mechanobiology. Cytoskeleton (Hoboken). 2021 06; 78(6):303-311.
    View in: PubMed
    Score: 0.044
  54. McCurdy DW, Kovar DR, Staiger CJ. Actin and actin-binding proteins in higher plants. Protoplasma. 2001; 215(1-4):89-104.
    View in: PubMed
    Score: 0.042
  55. Kovar DR, Staiger CJ, Weaver EA, McCurdy DW. AtFim1 is an actin filament crosslinking protein from Arabidopsis thaliana. Plant J. 2000 Dec; 24(5):625-36.
    View in: PubMed
    Score: 0.042
  56. Hu S, Brady SR, Kovar DR, Staiger CJ, Clark GB, Roux SJ, Muday GK. Technical advance: identification of plant actin-binding proteins by F-actin affinity chromatography. Plant J. 2000 Oct; 24(1):127-37.
    View in: PubMed
    Score: 0.042
  57. Kovar DR, Drøbak BK, Staiger CJ. Maize profilin isoforms are functionally distinct. Plant Cell. 2000 Apr; 12(4):583-98.
    View in: PubMed
    Score: 0.040
  58. Mancl JM, Suarez C, Liang WG, Kovar DR, Tang WJ. Pseudomonas aeruginosa exoenzyme Y directly bundles actin filaments. J Biol Chem. 2020 03 13; 295(11):3506-3517.
    View in: PubMed
    Score: 0.040
  59. Haase S, Zimmermann D, Olshina MA, Wilkinson M, Fisher F, Tan YH, Stewart RJ, Tonkin CJ, Wong W, Kovar DR, Baum J. Disassembly activity of actin-depolymerizing factor (ADF) is associated with distinct cellular processes in apicomplexan parasites. Mol Biol Cell. 2015 Sep 01; 26(17):3001-12.
    View in: PubMed
    Score: 0.029
  60. Davies T, Jordan SN, Chand V, Sees JA, Laband K, Carvalho AX, Shirasu-Hiza M, Kovar DR, Dumont J, Canman JC. High-resolution temporal analysis reveals a functional timeline for the molecular regulation of cytokinesis. Dev Cell. 2014 Jul 28; 30(2):209-23.
    View in: PubMed
    Score: 0.027
  61. Kang Y, Jelenska J, Cecchini NM, Li Y, Lee MW, Kovar DR, Greenberg JT. HopW1 from Pseudomonas syringae disrupts the actin cytoskeleton to promote virulence in Arabidopsis. PLoS Pathog. 2014 Jun; 10(6):e1004232.
    View in: PubMed
    Score: 0.027
  62. Wong W, Webb AI, Olshina MA, Infusini G, Tan YH, Hanssen E, Catimel B, Suarez C, Condron M, Angrisano F, Nebi T, Kovar DR, Baum J. A mechanism for actin filament severing by malaria parasite actin depolymerizing factor 1 via a low affinity binding interface. J Biol Chem. 2014 Feb 14; 289(7):4043-54.
    View in: PubMed
    Score: 0.026
  63. Namgoong S, Boczkowska M, Glista MJ, Winkelman JD, Rebowski G, Kovar DR, Dominguez R. Mechanism of actin filament nucleation by Vibrio VopL and implications for tandem W domain nucleation. Nat Struct Mol Biol. 2011 Aug 28; 18(9):1060-7.
    View in: PubMed
    Score: 0.022
  64. Ezezika OC, Younger NS, Lu J, Kaiser DA, Corbin ZA, Nolen BJ, Kovar DR, Pollard TD. Incompatibility with formin Cdc12p prevents human profilin from substituting for fission yeast profilin: insights from crystal structures of fission yeast profilin. J Biol Chem. 2009 Jan 23; 284(4):2088-97.
    View in: PubMed
    Score: 0.018
  65. Wu JQ, Sirotkin V, Kovar DR, Lord M, Beltzner CC, Kuhn JR, Pollard TD. Assembly of the cytokinetic contractile ring from a broad band of nodes in fission yeast. J Cell Biol. 2006 Jul 31; 174(3):391-402.
    View in: PubMed
    Score: 0.016
  66. Wu JQ, Kuhn JR, Kovar DR, Pollard TD. Spatial and temporal pathway for assembly and constriction of the contractile ring in fission yeast cytokinesis. Dev Cell. 2003 Nov; 5(5):723-34.
    View in: PubMed
    Score: 0.013
  67. Schobert C, Gottschalk M, Kovar DR, Staiger CJ, Yoo BC, Lucas WJ. Characterization of Ricinus communis phloem profilin, RcPRO1. Plant Mol Biol. 2000 Mar; 42(5):719-30.
    View in: PubMed
    Score: 0.010
  68. Gibbon BC, Kovar DR, Staiger CJ. Latrunculin B has different effects on pollen germination and tube growth. Plant Cell. 1999 Dec; 11(12):2349-63.
    View in: PubMed
    Score: 0.010
  69. Gibbon BC, Zonia LE, Kovar DR, Hussey PJ, Staiger CJ. Pollen profilin function depends on interaction with proline-rich motifs. Plant Cell. 1998 Jun; 10(6):981-93.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.