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Erika C. Claud

InstitutionUniversity of Chicago
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Dr. Claud is a physician scientist who intended to be a full time clinician but discovered a passion for answering questions through laboratory investigation. She is committed to the questions being explored in her laboratory but also to encouraging medical students and trainees to consider research as an essential and feasible means of improving patient care.

    Dr. Claud is a Professor in the Department of Pediatrics, Section of Neonatology, and the Department of Medicine, Section of Gastroenterology. She received her combined undergraduate and medical degree at Northwestern University through the six year Honors Program in Medical Education, and then completed her Residency in Pediatrics at Children’s Memorial Hospital in Chicago. After spending 18 months in rural Kenya as a missionary physician, she returned to Chicago to complete her Neonatology Fellowship at Children’s Memorial Hospital.

    Following her clinical fellowship she was recruited to Harvard Medical School where she held a clinical position at The Boston Children’s Hospital and completed a research fellowship at Massachusetts General Hospital. She joined the faculty of the University of Chicago in 2004. She is NIH funded to investigate the role of microbes in intestinal development of the preterm infant and leads the MIND (Microbiome in Neonatal Development) cohort. The interaction between the intestine and its resident microbiota is a complex relationship with risk and benefit for the host. Perturbations in environmental cues or altered patterns of microbial selection can affect health and increase risk of disease in susceptible individuals. The simple microbial communities and limited environmental variation of the preterm infant provide a unique model in which to investigate microbial perturbations. Her laboratory utilizes state-of-the-art experimental approaches including: 16S rRNA and shotgun metagenomic analyses of the microbiome, gnotobiotic mouse models, rodent models of Neonatal Necrotizing Enterocolitis, as well as cell culture models of immature and mature intestine to investigate the health impact of the microbiome on health outcomes of preterm infants.

    She is co-director of the Basic Science Track within the Scholarship and Discovery Program of the Pritzker School of Medicine and Faculty Co-Chair Pritzker School of Medicine Summer Research Program. She is also Director of Neonatology Research and a member of the Faculty Leadership Cabinet for the Duchossois Family Institute.

    Collapse Biography 
    Collapse education and training
    Northwestern University, Evanston, ILBS1988Medicine
    Northwestern Feinberg School of Medicine, Chicago, ILMD1990Medicine
    Children's Memorial Hospital, Chicago, ILInternship and Residency1993Pediatrics
    Children's Memorial Hospital, Chicago, ILFellowship2000Neonatology
    Massachusetts General Hospital, Boston, MAResearch Fellowship2003
    Collapse awards and honors
    1984 - 1990Honors Program in Medical Education, Northwestern University
    1989Alpha Omega Alpha
    1997Frederick M. Kenny Award in Pediatric Research
    2005Elected to Society for Pediatric Research
    2009 - 2011March of Dimes Basil O’Connor Starter Scholar Award
    2014Elected to American Pediatrics Society
    2014The George M Eisenberg Foundation for Charities Excellence in Pediatrics Award, The University of Chicago
    2018The Inaugural Peter Huttenlocher Award for Scholarly Excellence, The University of Chicago

    Collapse Research 
    Collapse research activities and funding
    UG3OD023281     (CLAUD, ERIKA C)Sep 21, 2016 - Aug 31, 2018
    The microbiome as a potential mediator of socio-economic disparities in preterm infant neurodevelopmental trajectories from NICU discharge to school age
    Role: Principal Investigator

    R01HD083481     (CLAUD, ERIKA C)Mar 1, 2015 - Jan 31, 2020
    Preterm infant susceptibility to NEC due to early intestinal microbiome function
    Role: Principal Investigator

    R01HD059123     (CLAUD, ERIKA C)Jan 1, 2009 - Dec 31, 2014
    Immature intestinal NF-kB regulation, probiotics, and necrotizing enterocolitis
    Role: Principal Investigator

    R21AT004044     (CLAUD, ERIKA C)Aug 1, 2008 - Jun 30, 2010
    Use of Probiotic Conditioned Media to Protect Against Necrotizing Enterocolitis
    Role: Principal Investigator

    R21HD055237     (CLAUD, ERIKA C)Apr 1, 2008 - Mar 31, 2010
    Early Enterocyte Injury in Neonatal Necrotizing Enterocolitis
    Role: Principal Investigator

    K08HD043839     (CLAUD, ERIKA C)Jan 15, 2004 - Dec 31, 2008
    Regulation of Inflammation in Immature Intestine
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sizemore N, Oliphant K, Zheng R, Martin CR, Claud EC, Chattopadhyay I. A digital twin of the infant microbiome to predict neurodevelopmental deficits. Sci Adv. 2024 Apr 12; 10(15):eadj0400. PMID: 38598636; PMCID: PMC11006218.
    2. Oliphant K, Cruz Ayala W, Ilyumzhinova R, Mbayiwa K, Sroka A, Xie B, Andrews B, Keenan K, Claud EC. Microbiome function and neurodevelopment in Black infants: vitamin B12 emerges as a key factor. Gut Microbes. 2024 Jan-Dec; 16(1):2298697. PMID: 38303501; PMCID: PMC10841033.
      Citations: 1     Fields:    Translation:Humans
    3. Rodriguez NA, Moya F, Ladino J, Zauk A, Prazad P, Perez J, Vento M, Claud E, Wang CH, Caplan MS. Correction to: A randomized controlled trial of oropharyngeal therapy with mother's own milk for premature infants. J Perinatol. 2023 Aug; 43(8):1084. PMID: 36646823.
      Citations:    Fields:    
    4. Sharma A, Yu Y, Lu J, Lu L, Zhang YG, Xia Y, Sun J, Claud EC. The Impact of Maternal Probiotics on Intestinal Vitamin D Receptor Expression in Early Life. Biomolecules. 2023 05 16; 13(5). PMID: 37238716; PMCID: PMC10216467.
      Citations: 1     Fields:    Translation:HumansAnimals
    5. Lu J, Drobyshevsky A, Lu L, Yu Y, Caplan MS, Claud EC. Microbiota from Preterm Infants Who Develop Necrotizing Enterocolitis Drives the Neurodevelopment Impairment in a Humanized Mouse Model. Microorganisms. 2023 Apr 26; 11(5). PMID: 37317106; PMCID: PMC10224461.
      Citations: 1     
    6. Xia J, Claud EC. Gut Microbiome-Brain Axis as an Explanation for the Risk of Poor Neurodevelopment Outcome in Preterm Infants with Necrotizing Enterocolitis. Microorganisms. 2023 Apr 15; 11(4). PMID: 37110458; PMCID: PMC10142133.
      Citations: 1     
    7. Rodriguez NA, Moya F, Zauk A, Prazad P, Perez J, Vento M, Claud E, Wang CH, Caplan MS, Ladino J. A randomized controlled trial of oropharyngeal therapy with mother's own milk for premature infants. J Perinatol. 2023 05; 43(5):601-607. PMID: 36596945.
      Citations: 1     Fields:    Translation:Humans
    8. Lu J, Fan X, Lu L, Yu Y, Markiewicz E, Little JC, Sidebottom AM, Claud EC. Limosilactobacillus reuteri normalizes blood-brain barrier dysfunction and neurodevelopment deficits associated with prenatal exposure to lipopolysaccharide. Gut Microbes. 2023 Jan-Dec; 15(1):2178800. PMID: 36799469; PMCID: PMC9980478.
      Citations: 5     Fields:    Translation:HumansCells
    9. Lu J, Martin CR, Claud EC. Neurodevelopmental outcome of infants who develop necrotizing enterocolitis: The gut-brain axis. Semin Perinatol. 2023 02; 47(1):151694. PMID: 36572620; PMCID: PMC9974904.
      Citations: 6     Fields:    Translation:Humans
    10. Oliphant K, Claud EC. Early probiotics shape microbiota. Nat Microbiol. 2022 10; 7(10):1506-1507. PMID: 36163499.
      Citations: 5     Fields:    
    11. Lu J, Lu L, Yu Y, Oliphant K, Drobyshevsky A, Claud EC. Early preterm infant microbiome impacts adult learning. Sci Rep. 2022 02 28; 12(1):3310. PMID: 35228616; PMCID: PMC8885646.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    12. Stratakis N, Garcia E, Chandran A, Hsu T, Alshawabkeh A, Aris IM, Aschner JL, Breton C, Burbank A, Camargo CA, Carroll KN, Chen Z, Claud EC, Dabelea D, Dunlop AL, Elliott AJ, Ferrara A, Ganiban JM, Gern JE, Gold DR, Gower WA, Hertz-Picciotto I, Karagas MR, Karr CJ, Lester B, Leve LD, Litonjua AA, Ludena Y, McEvoy CT, Miller RL, Mueller NT, O'Connor TG, Oken E, O'Shea TM, Perera F, Stanford JB, Rivera-Spoljaric K, Rundle A, Trasande L, Wright RJ, Zhang Y, Zhu Y, Berhane K, Gilliland F, Chatzi L, on behalf of program collaborators for Environmental Influences on . The Role of Childhood Asthma in Obesity Development: A Nationwide US Multicohort Study. Epidemiology. 2022 01 01; 33(1):131-140. PMID: 34561347; PMCID: PMC8633057.
      Citations: 4     Fields:    Translation:Humans
    13. Walls Castellanos M, Claud EC. The microbiome, guard or threat to infant health. Trends Mol Med. 2021 12; 27(12):1175-1186. PMID: 34518093.
      Citations: 5     Fields:    Translation:Humans
    14. Amato KR, Arrieta MC, Azad MB, Bailey MT, Broussard JL, Bruggeling CE, Claud EC, Costello EK, Davenport ER, Dutilh BE, Swain Ewald HA, Ewald P, Hanlon EC, Julion W, Keshavarzian A, Maurice CF, Miller GE, Preidis GA, Singer B, Subramanian S, Zhao L, Kuzawa CW, Segurel L. The human gut microbiome and health inequities. Proc Natl Acad Sci U S A. 2021 06 22; 118(25). PMID: 34161260; PMCID: PMC8237592.
      Citations: 41     Fields:    Translation:Humans
    15. Peery RC, Pammi M, Claud E, Shen L. Epigenome - A mediator for host-microbiome crosstalk. Semin Perinatol. 2021 10; 45(6):151455. PMID: 34246487.
      Citations: 6     Fields:    Translation:Humans
    16. Kim CS, Grady N, Derrick M, Yu Y, Oliphant K, Lu J, Claud EC. Effect of Antibiotic Use Within First 48 Hours of Life on the Preterm Infant Microbiome: A Randomized Clinical Trial. JAMA Pediatr. 2021 03 01; 175(3):303-305. PMID: 33196773; PMCID: PMC7670395.
      Citations: 9     Fields:    Translation:HumansAnimals
    17. Lu L, Lu J, Yu Y, Claud E. Necrotizing enterocolitis intestinal barrier function protection by antenatal dexamethasone and surfactant-D in a rat model. Pediatr Res. 2021 10; 90(4):768-775. PMID: 33469185; PMCID: PMC8566228.
      Citations: 2     Fields:    Translation:HumansAnimals
    18. Oliphant K, Ali M, D'Souza M, Hughes PD, Sulakhe D, Wang AZ, Xie B, Yeasin R, Msall ME, Andrews B, Claud EC. Bacteroidota and Lachnospiraceae integration into the gut microbiome at key time points in early life are linked to infant neurodevelopment. Gut Microbes. 2021 Jan-Dec; 13(1):1997560. PMID: 34839801; PMCID: PMC8632288.
      Citations: 23     Fields:    Translation:HumansCells
    19. Ronan V, Yeasin R, Claud EC. Childhood Development and the Microbiome-The Intestinal Microbiota in Maintenance of Health and Development of Disease During Childhood Development. Gastroenterology. 2021 01; 160(2):495-506. PMID: 33307032; PMCID: PMC8714606.
      Citations: 49     Fields:    Translation:Humans
    20. Skondra D, Rodriguez SH, Sharma A, Gilbert J, Andrews B, Claud EC. The early gut microbiome could protect against severe retinopathy of prematurity. J AAPOS. 2020 08; 24(4):236-238. PMID: 32707176; PMCID: PMC7680397.
      Citations: 11     Fields:    Translation:Humans
    21. Lu J, Lu L, Yu Y, Baranowski J, Claud EC. Maternal administration of probiotics promotes brain development and protects offspring's brain from postnatal inflammatory insults in C57/BL6J mice. Sci Rep. 2020 05 18; 10(1):8178. PMID: 32424168; PMCID: PMC7235088.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    22. Lock JY, Carlson TL, Yu Y, Lu J, Claud EC, Carrier RL. Impact of Developmental Age, Necrotizing Enterocolitis Associated Stress, and Oral Therapeutic Intervention on Mucus Barrier Properties. Sci Rep. 2020 04 21; 10(1):6692. PMID: 32317678; PMCID: PMC7174379.
      Citations: 9     Fields:    Translation:AnimalsCells
    23. Baranowski JR, Claud EC. Necrotizing Enterocolitis and the Preterm Infant Microbiome. Adv Exp Med Biol. 2019; 1125:25-36. PMID: 30680646.
      Citations: 32     Fields:    Translation:Humans
    24. Kim CS, Claud EC. Necrotizing Enterocolitis Pathophysiology: How Microbiome Data Alter Our Understanding. Clin Perinatol. 2019 03; 46(1):29-38. PMID: 30771817; PMCID: PMC6816463.
      Citations: 10     Fields:    Translation:Humans
    25. Lu J, Claud EC. Connection between gut microbiome and brain development in preterm infants. Dev Psychobiol. 2019 07; 61(5):739-751. PMID: 30460694; PMCID: PMC6728148.
      Citations: 49     Fields:    Translation:Humans
    26. Guzman-Rodriguez M, McDonald JAK, Hyde R, Allen-Vercoe E, Claud EC, Sheth PM, Petrof EO. Using bioreactors to study the effects of drugs on the human microbiota. Methods. 2018 10 01; 149:31-41. PMID: 30102990.
      Citations: 18     Fields:    Translation:Humans
    27. Lu J, Synowiec S, Lu L, Yu Y, Yarnykh V, Caplan J, Caplan M, Claud EC, Drobyshevsky A, Bretherick T, Takada S. Microbiota influence the development of the brain and behaviors in C57BL/6J mice. PLoS One. 2018; 13(8):e0201829. PMID: 30075011; PMCID: PMC6075787.
      Citations: 62     Fields:    Translation:AnimalsCells
    28. Lu J, Lu L, Yu Y, Cluette-Brown J, Martin CR, Claud EC. Effects of Intestinal Microbiota on Brain Development in Humanized Gnotobiotic Mice. Sci Rep. 2018 04 03; 8(1):5443. PMID: 29615691; PMCID: PMC5882882.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    29. Lu L, Claud EC. Intrauterine Inflammation, Epigenetics, and Microbiome Influences on Preterm Infant Health. Curr Pathobiol Rep. 2018; 6(1):15-21. PMID: 29938128; PMCID: PMC5978889.
      Citations: 13     
    30. Foley SL, Allgaier B, Martin CR, Claud EC, Ravi A, Estensmo ELF, Abée-Lund TML, Rudi K. Association of the gut microbiota mobilome with hospital location and birth weight in preterm infants. Pediatr Res. 2017 Nov; 82(5):829-838. PMID: 28665922.
      Citations: 11     Fields:    Translation:HumansCells
    31. Yu Y, Lu L, Sun J, Petrof EO, Claud EC. Preterm infant gut microbiota affects intestinal epithelial development in a humanized microbiome gnotobiotic mouse model. Am J Physiol Gastrointest Liver Physiol. 2016 09 01; 311(3):G521-32. PMID: 27492329; PMCID: PMC5076002.
      Citations: 44     Fields:    Translation:HumansAnimals
    32. Martz SL, Guzman-Rodriguez M, He SM, Noordhof C, Hurlbut DJ, Gloor GB, Carlucci C, Weese S, Allen-Vercoe E, Sun J, Claud EC, Petrof EO. A human gut ecosystem protects against C. difficile disease by targeting TcdA. J Gastroenterol. 2017 Apr; 52(4):452-465. PMID: 27329502; PMCID: PMC5177537.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    33. Munoz S, Guzman-Rodriguez M, Sun J, Zhang YG, Noordhof C, He SM, Allen-Vercoe E, Claud EC, Petrof EO. Rebooting the microbiome. Gut Microbes. 2016 07 03; 7(4):353-363. PMID: 27176179; PMCID: PMC4988458.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    34. Grady NG, Petrof EO, Claud EC. Microbial therapeutic interventions. Semin Fetal Neonatal Med. 2016 12; 21(6):418-423. PMID: 27133778; PMCID: PMC5079850.
      Citations: 7     Fields:    Translation:Humans
    35. DiBartolomeo ME, Claud EC. The Developing Microbiome of the Preterm Infant. Clin Ther. 2016 04; 38(4):733-9. PMID: 26947798; PMCID: PMC4851874.
      Citations: 13     Fields:    Translation:Humans
    36. Cortese R, Lu L, Yu Y, Ruden D, Claud EC. Epigenome-Microbiome crosstalk: A potential new paradigm influencing neonatal susceptibility to disease. Epigenetics. 2016 03 03; 11(3):205-15. PMID: 26909656; PMCID: PMC4854540.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    37. Claud EC, Petrof EO. Is Promoting Gut Microbial Diversity in Neonatal Enterocolitis the NECst Step? Dig Dis Sci. 2015 Dec; 60(12):3499-501. PMID: 26458920.
      Citations:    Fields:    Translation:HumansCells
    38. Martz SL, McDonald JA, Sun J, Zhang YG, Gloor GB, Noordhof C, He SM, Gerbaba TK, Blennerhassett M, Hurlbut DJ, Allen-Vercoe E, Claud EC, Petrof EO. Administration of defined microbiota is protective in a murine Salmonella infection model. Sci Rep. 2015 Nov 04; 5:16094. PMID: 26531327; PMCID: PMC4632038.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    39. Rodriguez NA, Vento M, Claud EC, Wang CE, Caplan MS. Oropharyngeal administration of mother's colostrum, health outcomes of premature infants: study protocol for a randomized controlled trial. Trials. 2015 Oct 12; 16:453. PMID: 26458907; PMCID: PMC4603349.
      Citations: 16     Fields:    Translation:Humans
    40. Zhang YG, Wu S, Lu R, Zhou D, Zhou J, Carmeliet G, Petrof E, Claud EC, Sun J. Tight junction CLDN2 gene is a direct target of the vitamin D receptor. Sci Rep. 2015 Jul 27; 5:10642. PMID: 26212084; PMCID: PMC4650691.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    41. Wu S, Yoon S, Zhang YG, Lu R, Xia Y, Wan J, Petrof EO, Claud EC, Chen D, Sun J. Vitamin D receptor pathway is required for probiotic protection in colitis. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 01; 309(5):G341-9. PMID: 26159695; PMCID: PMC4556945.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    42. Lu L, Yu Y, Guo Y, Wang Y, Chang EB, Claud EC. Transcriptional modulation of intestinal innate defense/inflammation genes by preterm infant microbiota in a humanized gnotobiotic mouse model. PLoS One. 2015; 10(4):e0124504. PMID: 25928420; PMCID: PMC4415773.
      Citations: 24     Fields:    Translation:HumansAnimals
    43. Claud EC, McDonald JA, He SM, Yu Y, Duong L, Sun J, Petrof EO. Differential expression of 26S proteasome subunits and functional activity during neonatal development. Biomolecules. 2014 Aug 29; 4(3):812-26. PMID: 25177858; PMCID: PMC4192673.
      Citations: 4     Fields:    Translation:AnimalsCells
    44. Wu S, Zhang YG, Lu R, Xia Y, Zhou D, Petrof EO, Claud EC, Chen D, Chang EB, Carmeliet G, Sun J. Intestinal epithelial vitamin D receptor deletion leads to defective autophagy in colitis. Gut. 2015 Jul; 64(7):1082-94. PMID: 25080448; PMCID: PMC4312277.
      Citations: 160     Fields:    Translation:HumansAnimalsCells
    45. Mustafi D, Shiou SR, Fan X, Markiewicz E, Karczmar GS, Claud EC. MRI of neonatal necrotizing enterocolitis in a rodent model. NMR Biomed. 2014 Mar; 27(3):272-9. PMID: 24318809; PMCID: PMC4282586.
      Citations: 3     Fields:    Translation:AnimalsCells
    46. Shiou SR, Yu Y, Guo Y, Westerhoff M, Lu L, Petrof EO, Sun J, Claud EC. Oral administration of transforming growth factor-ß1 (TGF-ß1) protects the immature gut from injury via Smad protein-dependent suppression of epithelial nuclear factor ?B (NF-?B) signaling and proinflammatory cytokine production. J Biol Chem. 2013 Nov 29; 288(48):34757-66. PMID: 24129565; PMCID: PMC3843089.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    47. Yu Y, Shiou SR, Guo Y, Lu L, Westerhoff M, Sun J, Petrof EO, Claud EC. Erythropoietin protects epithelial cells from excessive autophagy and apoptosis in experimental neonatal necrotizing enterocolitis. PLoS One. 2013; 8(7):e69620. PMID: 23936061; PMCID: PMC3723879.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    48. Claud EC, Keegan KP, Brulc JM, Lu L, Bartels D, Glass E, Chang EB, Meyer F, Antonopoulos DA. Bacterial community structure and functional contributions to emergence of health or necrotizing enterocolitis in preterm infants. Microbiome. 2013 Jul 10; 1(1):20. PMID: 24450928; PMCID: PMC3971604.
      Citations: 95     Fields:    
    49. Shiou SR, Yu Y, Guo Y, He SM, Mziray-Andrew CH, Hoenig J, Sun J, Petrof EO, Claud EC. Synergistic protection of combined probiotic conditioned media against neonatal necrotizing enterocolitis-like intestinal injury. PLoS One. 2013; 8(5):e65108. PMID: 23717690; PMCID: PMC3663790.
      Citations: 25     Fields:    Translation:AnimalsCells
    50. Petrof EO, Claud EC, Gloor GB, Allen-Vercoe E. Microbial ecosystems therapeutics: a new paradigm in medicine? Benef Microbes. 2013 Mar 01; 4(1):53-65. PMID: 23257018.
      Citations: 56     Fields:    Translation:HumansCells
    51. Musch MW, Wang Y, Claud EC, Chang EB. Lubiprostone decreases mouse colonic inner mucus layer thickness and alters intestinal microbiota. Dig Dis Sci. 2013 Mar; 58(3):668-77. PMID: 23329012; PMCID: PMC3618493.
      Citations: 23     Fields:    Translation:AnimalsCells
    52. Claud EC. First do no harm. J Pediatr Pharmacol Ther. 2012 Oct; 17(4):298-301. PMID: 23412919; PMCID: PMC3567883.
      Citations: 3     
    53. Lu R, Liu X, Wu S, Xia Y, Zhang YG, Petrof EO, Claud EC, Sun J. Consistent activation of the ß-catenin pathway by Salmonella type-three secretion effector protein AvrA in chronically infected intestine. Am J Physiol Gastrointest Liver Physiol. 2012 Nov 15; 303(10):G1113-25. PMID: 22982337; PMCID: PMC3517655.
      Citations: 33     Fields:    Translation:AnimalsCells
    54. Zhang YG, Wu S, Xia Y, Chen D, Petrof EO, Claud EC, Hsu W, Sun J. Axin1 prevents Salmonella invasiveness and inflammatory response in intestinal epithelial cells. PLoS One. 2012; 7(4):e34942. PMID: 22509369; PMCID: PMC3324539.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    55. Costello JM, McQuillen PS, Claud EC, Steinhorn RH. Prematurity and congenital heart disease. World J Pediatr Congenit Heart Surg. 2011 Jul 01; 2(3):457-67. PMID: 23803997.
      Citations: 2     Fields:    
    56. Liedel JL, Guo Y, Yu Y, Shiou SR, Chen S, Petrof EO, Hu S, Musch MW, Claud EC. Mother's milk-induced Hsp70 expression preserves intestinal epithelial barrier function in an immature rat pup model. Pediatr Res. 2011 May; 69(5 Pt 1):395-400. PMID: 21263375; PMCID: PMC3088164.
      Citations: 26     Fields:    Translation:AnimalsCells
    57. Nanthakumar N, Meng D, Goldstein AM, Zhu W, Lu L, Uauy R, Llanos A, Claud EC, Walker WA. The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innate immune response. PLoS One. 2011 Mar 21; 6(3):e17776. PMID: 21445298; PMCID: PMC3061868.
      Citations: 161     Fields:    Translation:HumansAnimals
    58. Claud EC. Probiotics and neonatal necrotizing enterocolitis. Anaerobe. 2011 Aug; 17(4):180-5. PMID: 21376824.
      Citations: 4     Fields:    Translation:Humans
    59. Shiou SR, Yu Y, Chen S, Ciancio MJ, Petrof EO, Sun J, Claud EC. Erythropoietin protects intestinal epithelial barrier function and lowers the incidence of experimental neonatal necrotizing enterocolitis. J Biol Chem. 2011 Apr 08; 286(14):12123-32. PMID: 21262973; PMCID: PMC3069416.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    60. Hu S, Wang Y, Lichtenstein L, Tao Y, Musch MW, Jabri B, Antonopoulos D, Claud EC, Chang EB. Regional differences in colonic mucosa-associated microbiota determine the physiological expression of host heat shock proteins. Am J Physiol Gastrointest Liver Physiol. 2010 Dec; 299(6):G1266-75. PMID: 20864653; PMCID: PMC3006241.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    61. Wu S, Ye Z, Liu X, Zhao Y, Xia Y, Steiner A, Petrof EO, Claud EC, Sun J. Salmonella typhimurium infection increases p53 acetylation in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2010 May; 298(5):G784-94. PMID: 20224008; PMCID: PMC2867426.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    62. Hu S, Claud EC, Musch MW, Chang EB. Stress granule formation mediates the inhibition of colonic Hsp70 translation by interferon-gamma and tumor necrosis factor-alpha. Am J Physiol Gastrointest Liver Physiol. 2010 Apr; 298(4):G481-92. PMID: 20110459; PMCID: PMC2853301.
      Citations: 18     Fields:    Translation:AnimalsCells
    63. Petrof EO, Claud EC, Sun J, Abramova T, Guo Y, Waypa TS, He SM, Nakagawa Y, Chang EB. Bacteria-free solution derived from Lactobacillus plantarum inhibits multiple NF-kappaB pathways and inhibits proteasome function. Inflamm Bowel Dis. 2009 Oct; 15(10):1537-47. PMID: 19373789; PMCID: PMC2748164.
      Citations: 38     Fields:    Translation:AnimalsCells
    64. Claud EC. Neonatal Necrotizing Enterocolitis -Inflammation and Intestinal Immaturity. Antiinflamm Antiallergy Agents Med Chem. 2009 Sep; 8(3):248-259. PMID: 20498729; PMCID: PMC2874244.
      Citations: 38     Fields:    
    65. Wang Y, Hoenig JD, Malin KJ, Qamar S, Petrof EO, Sun J, Antonopoulos DA, Chang EB, Claud EC. 16S rRNA gene-based analysis of fecal microbiota from preterm infants with and without necrotizing enterocolitis. ISME J. 2009 Aug; 3(8):944-54. PMID: 19369970; PMCID: PMC2713796.
      Citations: 288     Fields:    Translation:HumansCells
    66. Claud EC, Walker WA. Bacterial colonization, probiotics, and necrotizing enterocolitis. J Clin Gastroenterol. 2008 Jul; 42 Suppl 2:S46-52. PMID: 18520617.
      Citations: 41     Fields:    Translation:HumansCells
    67. Liao AP, Petrof EO, Kuppireddi S, Zhao Y, Xia Y, Claud EC, Sun J. Salmonella type III effector AvrA stabilizes cell tight junctions to inhibit inflammation in intestinal epithelial cells. PLoS One. 2008 Jun 04; 3(6):e2369. PMID: 18523661; PMCID: PMC2408728.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    68. Claud EC, Lu J, Wang XQ, Abe M, Petrof EO, Sun J, Nelson DJ, Marks J, Jilling T. Platelet-activating factor-induced chloride channel activation is associated with intracellular acidosis and apoptosis of intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1191-200. PMID: 18339705; PMCID: PMC2675178.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    69. Petrof EO, Musch MW, Ciancio M, Sun J, Hobert ME, Claud EC, Gewirtz A, Chang EB. Flagellin is required for salmonella-induced expression of heat shock protein Hsp25 in intestinal epithelium. Am J Physiol Gastrointest Liver Physiol. 2008 Mar; 294(3):G808-18. PMID: 18202113.
      Citations: 3     Fields:    Translation:AnimalsCells
    70. Ye Z, Petrof EO, Boone D, Claud EC, Sun J. Salmonella effector AvrA regulation of colonic epithelial cell inflammation by deubiquitination. Am J Pathol. 2007 Sep; 171(3):882-92. PMID: 17690189; PMCID: PMC1959497.
      Citations: 117     Fields:    Translation:HumansAnimalsCells
    71. Claud EC, Zhang X, Petrof EO, Sun J. Developmentally regulated tumor necrosis factor-alpha induced nuclear factor-kappaB activation in intestinal epithelium. Am J Physiol Gastrointest Liver Physiol. 2007 May; 292(5):G1411-9. PMID: 17307728.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    72. Claud EC, Lu L, Anton PM, Savidge T, Walker WA, Cherayil BJ. Developmentally regulated IkappaB expression in intestinal epithelium and susceptibility to flagellin-induced inflammation. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7404-8. PMID: 15123821; PMCID: PMC409931.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    73. Claud EC, Savidge T, Walker WA. Modulation of human intestinal epithelial cell IL-8 secretion by human milk factors. Pediatr Res. 2003 Mar; 53(3):419-25. PMID: 12595589.
      Citations: 54     Fields:    Translation:HumansCells
    74. Claud EC, Li D, Xiao Y, Caplan MS, Jilling T. Platelet-activating factor regulates chloride transport in colonic epithelial cell monolayers. Pediatr Res. 2002 Aug; 52(2):155-62. PMID: 12149490.
      Citations: 6     Fields:    Translation:HumansCells
    75. Claud EC, Walker WA, Claud EC, Walker WA. Hypothesis: inappropriate colonization of the premature intestine can cause neonatal necrotizing enterocolitis. FASEB J. 2001 Jun; 15(8):1398-403. PMID: 11387237.
      Citations: 123     Fields:    Translation:HumansCells
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