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Kathleen H. Goss

AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Press DJ, Ibraheem A, Dolan ME, Goss KH, Conzen S, Huo D. Racial disparities in omission of oncotype DX but no racial disparities in chemotherapy receipt following completed oncotype DX test results. Breast Cancer Res Treat. 2018 Feb; 168(1):207-220. PMID: 29181717.
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    2. Bainer RO, Trendowski MR, Cheng C, Pei D, Yang W, Paugh SW, Goss KH, Skol AD, Pavlidis P, Pui CH, Gilliam TC, Evans WE, Onel K. A p53-regulated apoptotic gene signature predicts treatment response and outcome in pediatric acute lymphoblastic leukemia. Cancer Manag Res. 2017; 9:397-410. PMID: 28979163.
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    3. Tao Y, Messer JS, Goss KH, Hart J, Bissonnette M, Chang EB. Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model. Carcinogenesis. 2016 07; 37(7):731-739. PMID: 27207671.
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    4. Xu J, Chen Y, Huo D, Khramtsov A, Khramtsova G, Zhang C, Goss KH, Olopade OI. ß-catenin regulates c-Myc and CDKN1A expression in breast cancer cells. Mol Carcinog. 2016 May; 55(5):431-9. PMID: 25663530.
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    5. Xu J, Prosperi JR, Choudhury N, Olopade OI, Goss KH. ß-Catenin is required for the tumorigenic behavior of triple-negative breast cancer cells. PLoS One. 2015; 10(2):e0117097. PMID: 25658419.
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    6. Lesko AC, Goss KH, Yang FF, Schwertner A, Hulur I, Onel K, Prosperi JR. The APC tumor suppressor is required for epithelial cell polarization and three-dimensional morphogenesis. Biochim Biophys Acta. 2015 Mar; 1853(3):711-23. PMID: 25578398.
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    7. Goss KH, Le Beau MM. Janet Davidson Rowley (1925-2013). Cancer Cell. 2014 Jan 13; 25(1):1-2. PMID: 24654260.
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    8. Lesko AC, Goss KH, Prosperi JR. Exploiting APC function as a novel cancer therapy. Curr Drug Targets. 2014 Jan; 15(1):90-102. PMID: 24200292.
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    9. Prosperi JR, Goss KH. Targeting loss of tumor suppressors for cancer therapeutics. Curr Drug Targets. 2014 Jan; 15(1):1. PMID: 24428573.
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    10. Shy BR, Wu CI, Khramtsova GF, Zhang JY, Olopade OI, Goss KH, Merrill BJ. Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/ß-catenin signaling. Cell Rep. 2013 Jul 11; 4(1):1-9. PMID: 23810553.
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    11. Odenwald MA, Prosperi JR, Goss KH. APC/ß-catenin-rich complexes at membrane protrusions regulate mammary tumor cell migration and mesenchymal morphology. BMC Cancer. 2013 Jan 09; 13:12. PMID: 23302090.
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    12. Prosperi JR, Khramtsov AI, Khramtsova GF, Goss KH. Apc mutation enhances PyMT-induced mammary tumorigenesis. PLoS One. 2011; 6(12):e29339. PMID: 22216254.
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    13. Zhu H, Dougherty U, Robinson V, Mustafi R, Pekow J, Kupfer S, Li YC, Hart J, Goss K, Fichera A, Joseph L, Bissonnette M. EGFR signals downregulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: role of G1 regulators. Mol Cancer Res. 2011 Jul; 9(7):960-75. PMID: 21653642.
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    14. Prosperi JR, Goss KH. A Wnt-ow of opportunity: targeting the Wnt/beta-catenin pathway in breast cancer. Curr Drug Targets. 2010 Sep; 11(9):1074-88. PMID: 20545611.
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    15. Khramtsov AI, Khramtsova GF, Tretiakova M, Huo D, Olopade OI, Goss KH. Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome. Am J Pathol. 2010 Jun; 176(6):2911-20. PMID: 20395444.
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    16. Meyer SE, Waltz SE, Goss KH. The Ron receptor tyrosine kinase is not required for adenoma formation in Apc(Min/+) mice. Mol Carcinog. 2009 Nov; 48(11):995-1004. PMID: 19452510.
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    17. Prosperi JR, Becher KR, Willson TA, Collins MH, Witte DP, Goss KH. The APC tumor suppressor is required for epithelial integrity in the mouse mammary gland. J Cell Physiol. 2009 Aug; 220(2):319-31. PMID: 19326388.
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    18. Mak GZ, Kavanaugh GM, Buschmann MM, Stickley SM, Koch M, Goss KH, Waechter H, Zuk A, Matlin KS. Regulated synthesis and functions of laminin 5 in polarized madin-darby canine kidney epithelial cells. Mol Biol Cell. 2006 Aug; 17(8):3664-77. PMID: 16775009.
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    19. Reichling T, Goss KH, Carson DJ, Holdcraft RW, Ley-Ebert C, Witte D, Aronow BJ, Groden J. Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors. Cancer Res. 2005 Jan 01; 65(1):166-76. PMID: 15665292.
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    20. Genter MB, Goss KH, Groden J. Strain-specific of alachlor on murine olfactory mucosal responses. Toxicol Pathol. 2004 Nov-Dec; 32(6):719-25. PMID: 15580706.
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    21. Liou GI, Samuel S, Matragoon S, Goss KH, Santoro I, Groden J, Hunt RC, Wang F, Miller SS, Caldwell RB, Rustgi AK, Singh H, Marcus DM. Alternative splicing of the APC gene in the neural retina and retinal pigment epithelium. Mol Vis. 2004 Jun 14; 10:383-91. PMID: 15218453.
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    22. Goss KH, Risinger MA, Kordich JJ, Sanz MM, Straughen JE, Slovek LE, Capobianco AJ, German J, Boivin GP, Groden J. Enhanced tumor formation in mice heterozygous for Blm mutation. Science. 2002 Sep 20; 297(5589):2051-3. PMID: 12242442.
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    23. Heinen CD, Goss KH, Cornelius JR, Babcock GF, Knudsen ES, Kowalik T, Groden J. The APC tumor suppressor controls entry into S-phase through its ability to regulate the cyclin D/RB pathway. Gastroenterology. 2002 Sep; 123(3):751-63. PMID: 12198702.
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    24. Langland G, Kordich J, Creaney J, Goss KH, Lillard-Wetherell K, Bebenek K, Kunkel TA, Groden J. The Bloom's syndrome protein (BLM) interacts with MLH1 but is not required for DNA mismatch repair. J Biol Chem. 2001 Aug 10; 276(32):30031-5. PMID: 11325959.
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    25. Goss KH, Groden J. Biology of the adenomatous polyposis coli tumor suppressor. J Clin Oncol. 2000 May; 18(9):1967-79. PMID: 10784639.
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