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Concurrent loss of LKB1 and KEAP1 enhances SHMT-mediated antioxidant defence in KRAS-mutant lung cancer.
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Concurrent loss of LKB1 and KEAP1 enhances SHMT-mediated antioxidant defence in KRAS-mutant lung cancer.
Concurrent loss of LKB1 and KEAP1 enhances SHMT-mediated antioxidant defence in KRAS-mutant lung cancer. Nat Metab. 2024 Jul; 6(7):1310-1328.
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PubMed
subject areas
Animals
Antioxidants
Carcinoma, Non-Small-Cell Lung
Cell Line, Tumor
Glycine Hydroxymethyltransferase
Humans
Kelch-Like ECH-Associated Protein 1
Lung Neoplasms
Mice
Mutation
NF-E2-Related Factor 2
Oxidative Stress
Proto-Oncogene Proteins p21(ras)
authors with profiles
Brandon Faubert