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Connection

Hening Lin to Sirtuin 2

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This is a "connection" page, showing publications Hening Lin has written about Sirtuin 2.
Hening Lin
Connection Strength
8.788
Sirtuin 2
  1. SIRT2-mediated ACSS2 K271 deacetylation suppresses lipogenesis under nutrient stress. Elife. 2025 May 07; 13.
    View in: PubMed
    Score: 0.869
  2. Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis. Proc Natl Acad Sci U S A. 2024 Apr 30; 121(18):e2319833121.
    View in: PubMed
    Score: 0.808
  3. Pharmacological Advantage of SIRT2-Selective versus pan-SIRT1-3 Inhibitors. ACS Chem Biol. 2021 07 16; 16(7):1266-1275.
    View in: PubMed
    Score: 0.663
  4. NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle. Nat Commun. 2020 02 26; 11(1):1067.
    View in: PubMed
    Score: 0.606
  5. SIRT2 and Lysine Fatty Acylation Regulate the Activity of RalB and Cell Migration. ACS Chem Biol. 2019 09 20; 14(9):2014-2023.
    View in: PubMed
    Score: 0.586
  6. A Glycoconjugated SIRT2 Inhibitor with Aqueous Solubility Allows Structure-Based Design of SIRT2 Inhibitors. ACS Chem Biol. 2019 08 16; 14(8):1802-1810.
    View in: PubMed
    Score: 0.583
  7. Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model. J Med Chem. 2019 04 25; 62(8):4131-4141.
    View in: PubMed
    Score: 0.571
  8. A Small-Molecule SIRT2 Inhibitor That Promotes K-Ras4a Lysine Fatty-Acylation. ChemMedChem. 2019 04 03; 14(7):744-748.
    View in: PubMed
    Score: 0.565
  9. Direct Comparison of SIRT2 Inhibitors: Potency, Specificity, Activity-Dependent Inhibition, and On-Target Anticancer Activities. ChemMedChem. 2018 09 19; 13(18):1890-1894.
    View in: PubMed
    Score: 0.545
  10. HPLC-Based Enzyme Assays for Sirtuins. Methods Mol Biol. 2018; 1813:225-234.
    View in: PubMed
    Score: 0.522
  11. SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a. Elife. 2017 12 14; 6.
    View in: PubMed
    Score: 0.520
  12. Lessons learned from a SIRT2-selective inhibitor. Oncotarget. 2016 04 26; 7(17):22971-2.
    View in: PubMed
    Score: 0.465
  13. A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity. Cancer Cell. 2016 Mar 14; 29(3):297-310.
    View in: PubMed
    Score: 0.461
  14. Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation. Nat Commun. 2022 08 02; 13(1):4494.
    View in: PubMed
    Score: 0.179
  15. Emerging roles of Sirtuin 2 in cardiovascular diseases. FASEB J. 2021 10; 35(10):e21841.
    View in: PubMed
    Score: 0.169
  16. High-Throughput Screening Identifies Ascorbyl Palmitate as a SIRT2 Deacetylase and Defatty-Acylase Inhibitor. ChemMedChem. 2021 11 19; 16(22):3484-3494.
    View in: PubMed
    Score: 0.168
  17. Substrate-Dependent Modulation of SIRT2 by a Fluorescent Probe, 1-Aminoanthracene. Biochemistry. 2020 10 13; 59(40):3869-3878.
    View in: PubMed
    Score: 0.158
  18. Deacylation Mechanism by SIRT2 Revealed in the 1'-SH-2'-O-Myristoyl Intermediate Structure. Cell Chem Biol. 2017 Mar 16; 24(3):339-345.
    View in: PubMed
    Score: 0.123
  19. SIRT2 Reverses 4-Oxononanoyl Lysine Modification on Histones. J Am Chem Soc. 2016 09 28; 138(38):12304-7.
    View in: PubMed
    Score: 0.119
  20. Efficient demyristoylase activity of SIRT2 revealed by kinetic and structural studies. Sci Rep. 2015 Feb 23; 5:8529.
    View in: PubMed
    Score: 0.107
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.