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Daniel Gruenstein

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentPediatrics-Cardiology
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Daniel H. Gruenstein, MD, is one of the few physicians in Illinois who is both Board Certified by the ABP to care for infants, children and teens with Congenital Heart Disease – abnormalities that affect the structure and function of a patient's heart - as well as holding specialized Board Certification from the ABIM to treat Adults with Congenital Heart Disease . He specializes in interventional cardiology, including intravascular stent placement, valve implantation, closure of holes in the heart, and hybrid cardiac catheterization procedures.

    Dr. Gruenstein's research focuses on innovations in cardiac device development. He has been the primary investigator on several pre-clinical and FDA approval studies that test new devices. He holds several provisional patents for his work.

    Dr. Gruenstein has served several roles in Medical Societies, including being elected the first President of the Pediatric/Congenital Interventional Cardiology Early Career Society (PICES) and being invited by the Society for Cardiovascular Angiography & Intervention (SCAI) to serve as the Chair of the Congenital Heart Disease meetings of the annual Scientific Sessions from 2019-2021.

    A devoted educator, Dr. Gruenstein mentors medical students, residents and fellows in interventional cardiology. He had served as one of only five instructors, Dr. Gruenstein trains approximately 20 percent of all cardiologists in the United States who use the Amplatzer Atrial Septal Occluder Device to treat atrial septal defects (holes in the wall between the upper chambers of the heart). He has directed several national hands-on workshops for adult and pediatric interventional cardiologists, teaching advanced therapeutic techniques.

    Dr. Gruenstein has made significant contribution to the medical literature, publishing abstracts, peer-reviewed articles, book chapters and more on key topics in pediatric cardiology.

    The recipient of numerous national awards, Dr. Gruenstein has been recognized by patients, students and peers alike. He has been honored with the Patients' Choice Award and Compassionate Doctor Award, and has been named to the list of "Best Doctors in America" by Best Doctors, Inc and Chicago Magazine's "Top Cardiologists".


    Collapse Biography 
    Collapse education and training
    Washington University, St LouisBA05/1992Biology
    University of Cincinnati, CincinnatiMD06/1996Medicine
    Cincinnati Children's Hospital, Cincinnati06/1999Pediatrics
    Cincinnati Children's Hospital, Cincinnati06/2002Pediatric Cardiology
    Collapse awards and honors
    2018Chicago's Top Cardiologists, Chicago Magazine
    2017 - 2019Top Doctors - Pediatric Cardiology, Castle-Connolly
    2010 - 2018Compassionate Care Award
    2010 - 2018Patients' Choice Award
    2007 - 2012Best Doctors in America
    Faculty Teaching Award, Brown University/Hasbro Children's Hospital

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Crystal MA, Morgan GJ, Danon S, Gray RG, Gruenstein DH, Gordon BM, Goldstein BH. Serial Versus Direct Dilation of Small Diameter Stents Results in a More Predictable and Complete Intentional Transcatheter Stent Fracture: A PICES Bench Testing Study. Pediatr Cardiol. 2018 Jan; 39(1):120-128. PMID: 28980053.
      View in: PubMed
    2. Gruenstein DH, Ebeid M, Radtke W, Moore P, Holzer R, Justino H. Transcatheter closure of patent ductus arteriosus using the AMPLATZERâ„¢ duct occluder II (ADO II). Catheter Cardiovasc Interv. 2017 May; 89(6):1118-1128. PMID: 28258658.
      View in: PubMed
    3. Danon S, Gray RG, Crystal MA, Morgan G, Gruenstein DH, Goldstein BH, Gordon BM. Expansion Characteristics of Stents Used in Congenital Heart Disease: Serial Dilation Offers Improved Expansion Potential Compared to Direct Dilation: Results from a Pediatric Interventional Cardiology Early Career Society (PICES) Investigation. Congenit Heart Dis. 2016 Dec; 11(6):741-750. PMID: 27463050.
      View in: PubMed
    4. Barncord K, Stauthammer C, Moen SL, Hanson M, Gruenstein DH. Stent placement for palliation of cor triatriatum dexter in a dog with suspected patent foramen ovale. J Vet Cardiol. 2016 Mar; 18(1):79-87. PMID: 26777393.
      View in: PubMed
    5. Nykanen DG, Forbes TJ, Du W, Divekar AA, Reeves JH, Hagler DJ, Fagan TE, Pedra CA, Fleming GA, Khan DM, Javois AJ, Gruenstein DH, Qureshi SA, Moore PM, Wax DH. CRISP: Catheterization RISk score for Pediatrics: A Report from the Congenital Cardiac Interventional Study Consortium (CCISC). Catheter Cardiovasc Interv. 2016 Feb 01; 87(2):302-9. PMID: 26527119.
      View in: PubMed
    6. Kobayashi D, Meadows J, Forbes TJ, Moore P, Javois AJ, Pedra CA, Du W, Gruenstein DH, Wax DF, Hill JA, Graziano JN, Fagan TE, Alvarez WM, Nykanen DG, Divekar AA. Standardizing radiation dose reporting in the pediatric cardiac catheterization laboratory-a multicenter study by the CCISC (Congenital Cardiovascular Interventional Study Consortium). Catheter Cardiovasc Interv. 2014 Nov 01; 84(5):785-93. PMID: 24585540.
      View in: PubMed
    7. Aldoss O, Arain N, Menk J, Kochilas L, Gruenstein D. Endovascular stent provides more effective early relief of SVC obstruction compared to balloon angioplasty. Catheter Cardiovasc Interv. 2014 Jun 01; 83(7):E272-6. PMID: 22431347.
      View in: PubMed
    8. McDevitt H, Stauthammer C, Leeder D, Hanson M, Olson J, Gruenstein D. Palliative balloon angioplasty in a cat with right pulmonary arterial branch stenoses and concurrent absence of the left pulmonary artery. J Vet Cardiol. 2013 Sep; 15(3):211-6. PMID: 23932425.
      View in: PubMed
    9. Aldoss O, Arain NI, Vinocur JM, Menk J, Ameduri RK, Bryant R, Kochilas LK, Gruenstein DH. Frequency of superior vena cava obstruction in pediatric heart transplant recipients and its relation to previous superior cavopulmonary anastomosis. Am J Cardiol. 2013 Jul 15; 112(2):286-91. PMID: 23587279.
      View in: PubMed
    10. Aldoss O, Gruenstein DH, Bass JL, Steinberger J, Zhang Y, Defor TE, Tolar J, Verneris MR, Orchard PJ. Pericardial effusion after pediatric hematopoietic cell transplant. Pediatr Transplant. 2013 May; 17(3):294-9. PMID: 23464863.
      View in: PubMed
    11. Forbes TJ, Kim DW, Du W, Turner DR, Holzer R, Amin Z, Hijazi Z, Ghasemi A, Rome JJ, Nykanen D, Zahn E, Cowley C, Hoyer M, Waight D, Gruenstein D, Javois A, Foerster S, Kreutzer J, Sullivan N, Khan A, Owada C, Hagler D, Lim S, Canter J, Zellers T. Comparison of surgical, stent, and balloon angioplasty treatment of native coarctation of the aorta: an observational study by the CCISC (Congenital Cardiovascular Interventional Study Consortium). J Am Coll Cardiol. 2011 Dec 13; 58(25):2664-74. PMID: 22152954.
      View in: PubMed
    12. Bass JL, Gruenstein D. Transcatheter closure of the perimembranous ventricular septal defect-preclinical trial of a new Amplatzer device. Catheter Cardiovasc Interv. 2012 Jun 01; 79(7):1153-60. PMID: 22162409.
      View in: PubMed
    13. Holzer R, Qureshi S, Ghasemi A, Vincent J, Sievert H, Gruenstein D, Weber H, Alday L, Peirone A, Zellers T, Cheatham J, Slack M, Rome J. Stenting of aortic coarctation: acute, intermediate, and long-term results of a prospective multi-institutional registry--Congenital Cardiovascular Interventional Study Consortium (CCISC). Catheter Cardiovasc Interv. 2010 Oct 01; 76(4):553-63. PMID: 20882661.
      View in: PubMed
    14. Arain N, Bryant R, Ameduri R, Gruenstein D, Braunlin E, Joyce L, St Louis J. Successful Coil Embolization of a Large Ascending Aortic Pseudoaneurysm Following Explantation of the EXCOR Pediatric Ventricular Assist Device in a Patient With Acute Fulminant Myocarditis. World J Pediatr Congenit Heart Surg. 2010 Jul; 1(2):259-61. PMID: 23804831.
      View in: PubMed
    15. Gruenstein DH, Bass JL. Experimental evaluation of a new articulated Amplatzer ductal occluder device without fabric. Catheter Cardiovasc Interv. 2009 Sep 01; 74(3):482-7. PMID: 19405162.
      View in: PubMed
    16. Gruenstein DH, Beekman RH, Spicer RL. Ductal stent and cavo-atrial sac occlusion in an adult with profound cyanosis after palliated cyanotic congenital heart disease. J Invasive Cardiol. 2008 Feb; 20(2):E41-3. PMID: 18252976.
      View in: PubMed
    17. Ashwath R, Gruenstein D, Siwik E. Percutaneous stent placement in children weighing less than 10 kilograms. Pediatr Cardiol. 2008 May; 29(3):562-7. PMID: 18046599.
      View in: PubMed
    18. Chun TU, Gruenstein DH, Cripe LH, Beekman RH. Blade consolidation of multiple atrial septal defects: a novel approach to transcatheter closure. Pediatr Cardiol. 2004 Nov-Dec; 25(6):671-4. PMID: 15175838.
      View in: PubMed
    19. Gruenstein DH, Spicer RL, Shim D, Beekman RH. Pulmonary venous wedge pressure provides an accurate assessment of pulmonary artery pressure in children with a bidirectional Glenn shunt. J Interv Cardiol. 2003 Oct; 16(5):367-70. PMID: 14603791.
      View in: PubMed
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