Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway.

Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway. Int J Neuropsychopharmacol. 2013 May; 16(4):835-47.

View in: PubMed

subject areas

Animals
Carbazoles
Cells, Cultured
Corticosterone
Cyclic GMP
Cyclic GMP-Dependent Protein Kinases
Cyclic Nucleotide Phosphodiesterases, Type 2
Dose-Response Relationship, Drug
Female
Hippocampus
Imidazoles
Male
Mice
Phosphodiesterase Inhibitors
Pregnancy
Protein Kinase Inhibitors
Rats
Rats, Sprague-Dawley
Signal Transduction
Stress, Psychological
Triazines

authors with profiles

James O'Donnell