D000587Chemicals & DrugsD08.811.682.6627190.985566Oxidoreductases Acting on CH-NH Group Donorsplugins:TwitterTwitterprns:emailEncryptedemail addressprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson1.665080.0109587research area of0.8377310.044473914subject area forEcology and EvolutionSarahTerseySarah Tersey41.7886000000000087.598699999999993888Tersey, SarahResearch Associate ProfessorRaghuMirmiraRaghu Mirmira41.7886000000000087.598699999999993890Mirmira, RaghuProfessor20956533Robbins RD, Tersey SA, Ogihara T, Gupta D, Farb TB, Ficorilli J, Bokvist K, Maier B, Mirmira RGThe Journal of biological chemistryInhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes. J Biol Chem. 2010 Dec 17; 285(51):39943-52.J Biol Chem2010-10-18T00:00:002010Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes.30661771Ganapathi M, Padgett LR, Yamada K, Devinsky O, Willaert R, Person R, Au PB, Tagoe J, McDonald M, Karlowicz D, Wolf B, Lee J, Shen Y, Okur V, Deng L, LeDuc CA, Wang J, Hanner A, Mirmira RG, Park MH, Mastracci TL, Chung WKAmerican journal of human geneticsRecessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder. Am J Hum Genet. 2019 02 07; 104(2):287-298.Am J Hum Genet2019-01-17T00:00:002019Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder.24196968Colvin SC, Maier B, Morris DL, Tersey SA, Mirmira RGThe Journal of biological chemistryDeoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes. J Biol Chem. 2013 Dec 20; 288(51):36226-35.J Biol Chem2013-11-06T00:00:002013Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes.21389784Templin AT, Maier B, Nishiki Y, Tersey SA, Mirmira RGCell cycle (Georgetown, Tex.)Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling. Cell Cycle. 2011 Apr 01; 10(7):1043-9.Cell Cycle2011-04-01T00:00:002011Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling.RyanAndersonRyan Anderson41.7886000000000087.598699999999993911Anderson, RyanResearch Assistant Professor34496231Anderson-Baucum E, PiƱeros AR, Kulkarni A, Webb-Robertson BJ, Maier B, Anderson RM, Wu W, Tersey SA, Mastracci TL, Casimiro I, Scheuner D, Metz TO, Nakayasu ES, Evans-Molina C, Mirmira RGCell metabolismDeoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype. Cell Metab. 2021 09 07; 33(9):1883-1893.e7.Cell Metab2021-09-07T00:00:002021Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype.https://voices.uchicago.edu/mirmiralab/Mirmira LabSarahTerseyHuman GeneticsUniversity of ChicagoSomaDasxGZoGIF1GuTQkntjbwjr93A=Soma Das41.78927490000000-87.601250000000001471Das, SomaProfessorMichael Z.LudwigMichael Z. Ludwig41.78927490000000-87.60125000000000622Ludwig, Michael Z.Research Associate Professortrue1Research Associate ProfessorResearch Associate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Research Assistant ProfessorResearch Assistant Professortrue1Research Associate ProfessorResearch Associate ProfessorMedicine-Endocrinology