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Alexander Pearson to Humans

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This is a "connection" page, showing publications Alexander Pearson has written about Humans.
Alexander Pearson
Connection Strength
0.977
Humans
  1. Generative adversarial networks accurately reconstruct pan-cancer histology from pathologic, genomic, and radiographic latent features. Sci Adv. 2024 Nov 15; 10(46):eadq0856.
    View in: PubMed
    Score: 0.032
  2. Developing a low-cost, open-source, locally manufactured workstation and computational pipeline for automated histopathology evaluation using deep learning. EBioMedicine. 2024 Sep; 107:105276.
    View in: PubMed
    Score: 0.031
  3. Quantum computing for oncology. Nat Cancer. 2024 Jun; 5(6):811-816.
    View in: PubMed
    Score: 0.031
  4. Characterizing the Increase in Artificial Intelligence Content Detection in Oncology Scientific Abstracts From 2021 to 2023. JCO Clin Cancer Inform. 2024 May; 8:e2400077.
    View in: PubMed
    Score: 0.031
  5. Deep learning applications in visual data for benign and malignant hematologic conditions: a systematic review and visual glossary. Haematologica. 2023 08 01; 108(8):1993-2010.
    View in: PubMed
    Score: 0.029
  6. Applications of Deep Learning in Endocrine Neoplasms. Surg Pathol Clin. 2023 Mar; 16(1):167-176.
    View in: PubMed
    Score: 0.028
  7. Multimodal deep learning: An improvement in prognostication or a reflection of batch effect? Cancer Cell. 2023 01 09; 41(1):5-6.
    View in: PubMed
    Score: 0.028
  8. Uncertainty-informed deep learning models enable high-confidence predictions for digital histopathology. Nat Commun. 2022 11 02; 13(1):6572.
    View in: PubMed
    Score: 0.028
  9. Ovarian cancer through a multi-modal lens. Nat Cancer. 2022 06; 3(6):662-664.
    View in: PubMed
    Score: 0.027
  10. Development and Validation of a Decision Analytical Model for Posttreatment Surveillance for Patients With Oropharyngeal Carcinoma. JAMA Netw Open. 2022 04 01; 5(4):e227240.
    View in: PubMed
    Score: 0.026
  11. Current and future uses of digital pathology in oncology. Clin Adv Hematol Oncol. 2021 Aug; 19(8):508-510.
    View in: PubMed
    Score: 0.025
  12. The impact of site-specific digital histology signatures on deep learning model accuracy and bias. Nat Commun. 2021 07 20; 12(1):4423.
    View in: PubMed
    Score: 0.025
  13. Is This the Dawn of Precision Oncology in Head and Neck Cancer? J Clin Oncol. 2021 06 10; 39(17):1839-1841.
    View in: PubMed
    Score: 0.025
  14. Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features. Mod Pathol. 2021 05; 34(5):862-874.
    View in: PubMed
    Score: 0.024
  15. Machine Learning-Guided Adjuvant Treatment of Head and Neck Cancer. JAMA Netw Open. 2020 11 02; 3(11):e2025881.
    View in: PubMed
    Score: 0.024
  16. Academics as leaders in the cancer artificial intelligence revolution. Cancer. 2021 03 01; 127(5):664-671.
    View in: PubMed
    Score: 0.024
  17. Prognosis and Treatment of Non-Small Cell Lung Cancer in the Age of Deep Learning. JAMA Netw Open. 2020 06 01; 3(6):e206368.
    View in: PubMed
    Score: 0.023
  18. Inactivating NF1 Mutations Are Enriched in Advanced Breast Cancer and Contribute to Endocrine Therapy Resistance. Clin Cancer Res. 2020 02 01; 26(3):608-622.
    View in: PubMed
    Score: 0.022
  19. Hyperprogression-Immunotherapy-Related Phenomenon vs Intrinsic Natural History of Cancer. JAMA Oncol. 2019 05 01; 5(5):743.
    View in: PubMed
    Score: 0.022
  20. Modeling head and neck cancer stem cell-mediated tumorigenesis. Cell Mol Life Sci. 2016 09; 73(17):3279-89.
    View in: PubMed
    Score: 0.018
  21. Patient-derived xenograft (PDX) tumors increase growth rate with time. Oncotarget. 2016 Feb 16; 7(7):7993-8005.
    View in: PubMed
    Score: 0.017
  22. PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands. J Exp Clin Cancer Res. 2025 Jan 11; 44(1):11.
    View in: PubMed
    Score: 0.008
  23. Applications of artificial intelligence to myeloproliferative neoplasms: a narrative review. Expert Rev Hematol. 2024 Oct; 17(10):669-677.
    View in: PubMed
    Score: 0.008
  24. Artificial Intelligence Applications in Oral Cancer and Oral Dysplasia. Tissue Eng Part A. 2024 Oct; 30(19-20):640-651.
    View in: PubMed
    Score: 0.008
  25. Carcinoma-associated mesenchymal stem cells promote ovarian cancer heterogeneity and metastasis through mitochondrial transfer. Cell Rep. 2024 08 27; 43(8):114551.
    View in: PubMed
    Score: 0.008
  26. Neoadjuvant Nivolumab Plus Chemotherapy Followed By Response-Adaptive Therapy for HPV+ Oropharyngeal Cancer: OPTIMA II Phase 2 Open-Label Nonrandomized Controlled Trial. JAMA Oncol. 2024 Jul 01; 10(7):923-931.
    View in: PubMed
    Score: 0.008
  27. Using histopathology latent diffusion models as privacy-preserving dataset augmenters improves downstream classification performance. Comput Biol Med. 2024 06; 175:108410.
    View in: PubMed
    Score: 0.008
  28. Dysregulated FGFR3 signaling alters the immune landscape in bladder cancer and presents therapeutic possibilities in an agent-based model. Front Immunol. 2024; 15:1358019.
    View in: PubMed
    Score: 0.008
  29. Evolutionary dynamics of tipifarnib in HRAS mutated head and neck squamous cell carcinoma. Oral Oncol. 2024 Feb; 149:106688.
    View in: PubMed
    Score: 0.007
  30. Validation of the RSClin risk calculator in the National Cancer Data Base. Cancer. 2024 Apr 15; 130(8):1210-1220.
    View in: PubMed
    Score: 0.007
  31. Mathematical model predicts tumor control patterns induced by fast and slow cytotoxic T lymphocyte killing mechanisms. Sci Rep. 2023 12 18; 13(1):22541.
    View in: PubMed
    Score: 0.007
  32. Olaparib and Ceralasertib (AZD6738) in Patients with Triple-Negative Advanced Breast Cancer: Results from Cohort E of the plasmaMATCH Trial (CRUK/15/010). Clin Cancer Res. 2023 12 01; 29(23):4751-4759.
    View in: PubMed
    Score: 0.007
  33. The use of deep learning state-of-the-art architectures for oral epithelial dysplasia grading: A comparative appraisal. J Oral Pathol Med. 2023 Nov; 52(10):980-987.
    View in: PubMed
    Score: 0.007
  34. Deep learning-based subtyping of gastric cancer histology predicts clinical outcome: a multi-institutional retrospective study. Gastric Cancer. 2023 09; 26(5):708-720.
    View in: PubMed
    Score: 0.007
  35. Artificial Intelligence in Clinical Oncology: From Data to Digital Pathology and Treatment. Am Soc Clin Oncol Educ Book. 2023 May; 43:e390084.
    View in: PubMed
    Score: 0.007
  36. Adapting a Medical School Cancer Research Education Program to the Virtual Environment: a Mixed-Methods Study. J Cancer Educ. 2023 10; 38(5):1501-1508.
    View in: PubMed
    Score: 0.007
  37. Machine learning for the prediction of toxicities from head and neck cancer treatment: A systematic review with meta-analysis. Oral Oncol. 2023 05; 140:106386.
    View in: PubMed
    Score: 0.007
  38. Machine learning for detection and classification of oral potentially malignant disorders: A conceptual review. J Oral Pathol Med. 2023 Mar; 52(3):197-205.
    View in: PubMed
    Score: 0.007
  39. The EU-funded I3LUNG Project: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy. Clin Lung Cancer. 2023 06; 24(4):381-387.
    View in: PubMed
    Score: 0.007
  40. Machine learning concepts applied to oral pathology and oral medicine: A convolutional neural networks' approach. J Oral Pathol Med. 2023 Feb; 52(2):109-118.
    View in: PubMed
    Score: 0.007
  41. Highly accurate response prediction in high-risk early breast cancer patients using a biophysical simulation platform. Breast Cancer Res Treat. 2022 Nov; 196(1):57-66.
    View in: PubMed
    Score: 0.007
  42. A 2D Nanoradiosensitizer Enhances Radiotherapy and Delivers STING Agonists to Potentiate Cancer Immunotherapy. Adv Mater. 2022 Sep; 34(39):e2110588.
    View in: PubMed
    Score: 0.007
  43. Phase I study of nab-paclitaxel-based induction followed by nab-paclitaxel-based concurrent chemotherapy and re-irradiation in previously treated head and neck squamous cell carcinoma. Br J Cancer. 2022 11; 127(8):1497-1506.
    View in: PubMed
    Score: 0.007
  44. AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling. Cell Death Dis. 2022 08 05; 13(8):678.
    View in: PubMed
    Score: 0.007
  45. Clinical trials of immunotherapy in triple-negative breast cancer. Breast Cancer Res Treat. 2022 Aug; 195(1):1-15.
    View in: PubMed
    Score: 0.007
  46. Classical mathematical models for prediction of response to chemotherapy and immunotherapy. PLoS Comput Biol. 2022 02; 18(2):e1009822.
    View in: PubMed
    Score: 0.007
  47. Prospective study evaluating dynamic changes of cell-free HPV DNA in locoregional viral-associated oropharyngeal cancer treated with induction chemotherapy and response-adaptive treatment. BMC Cancer. 2022 Jan 03; 22(1):17.
    View in: PubMed
    Score: 0.007
  48. Application of liquid biopsy as multi-functional biomarkers in head and neck cancer. Br J Cancer. 2022 02; 126(3):361-370.
    View in: PubMed
    Score: 0.006
  49. The IL-6R and Bmi-1 axis controls self-renewal and chemoresistance of head and neck cancer stem cells. Cell Death Dis. 2021 10 23; 12(11):988.
    View in: PubMed
    Score: 0.006
  50. Risk and response adapted de-intensified treatment for HPV-associated oropharyngeal cancer: Optima paradigm expanded experience. Oral Oncol. 2021 11; 122:105566.
    View in: PubMed
    Score: 0.006
  51. A robust and interpretable gene signature for predicting the lymph node status of primary T1/T2 oral cavity squamous cell carcinoma. Int J Cancer. 2022 02 01; 150(3):450-460.
    View in: PubMed
    Score: 0.006
  52. The emerging role of immune checkpoint inhibitors for the treatment of breast cancer. Expert Opin Investig Drugs. 2022 Jun; 31(6):531-548.
    View in: PubMed
    Score: 0.006
  53. Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study. Lancet Digit Health. 2021 10; 3(10):e654-e664.
    View in: PubMed
    Score: 0.006
  54. COVIDomic: A multi-modal cloud-based platform for identification of risk factors associated with COVID-19 severity. PLoS Comput Biol. 2021 07; 17(7):e1009183.
    View in: PubMed
    Score: 0.006
  55. Deep learning detects genetic alterations in cancer histology generated by adversarial networks. J Pathol. 2021 05; 254(1):70-79.
    View in: PubMed
    Score: 0.006
  56. Wnt-ß-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression. Nat Immunol. 2021 04; 22(4):471-484.
    View in: PubMed
    Score: 0.006
  57. Long-term neck and shoulder function among survivors of oropharyngeal squamous cell carcinoma treated with chemoradiation as assessed with the neck dissection impairment index. Head Neck. 2021 05; 43(5):1621-1628.
    View in: PubMed
    Score: 0.006
  58. Survival of salivary gland cancer stem cells requires mTOR signaling. Cell Death Dis. 2021 01 21; 12(1):108.
    View in: PubMed
    Score: 0.006
  59. Deep learning in cancer pathology: a new generation of clinical biomarkers. Br J Cancer. 2021 02; 124(4):686-696.
    View in: PubMed
    Score: 0.006
  60. Human Endogenous Retrovirus Expression Is Associated with Head and Neck Cancer and Differential Survival. Viruses. 2020 08 28; 12(9).
    View in: PubMed
    Score: 0.006
  61. 4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis. Proc Natl Acad Sci U S A. 2020 09 08; 117(36):22423-22429.
    View in: PubMed
    Score: 0.006
  62. Pan-cancer image-based detection of clinically actionable genetic alterations. Nat Cancer. 2020 08; 1(8):789-799.
    View in: PubMed
    Score: 0.006
  63. Identifying predictors of HPV-related head and neck squamous cell carcinoma progression and survival through patient-derived models. Int J Cancer. 2020 12 01; 147(11):3236-3249.
    View in: PubMed
    Score: 0.006
  64. Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning. Gastroenterology. 2020 10; 159(4):1406-1416.e11.
    View in: PubMed
    Score: 0.006
  65. Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer. Nat Commun. 2020 05 29; 11(1):2662.
    View in: PubMed
    Score: 0.006
  66. A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target. J Clin Invest. 2020 03 02; 130(3):1405-1416.
    View in: PubMed
    Score: 0.006
  67. In Silico Models Accurately Predict In Vivo Response for IL6 Blockade in Head and Neck Cancer. Cancer Res. 2020 04 01; 80(7):1451-1460.
    View in: PubMed
    Score: 0.006
  68. The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View. Trends Cancer. 2020 03; 6(3):192-204.
    View in: PubMed
    Score: 0.006
  69. Machine learning can identify newly diagnosed patients with CLL at high risk of infection. Nat Commun. 2020 01 17; 11(1):363.
    View in: PubMed
    Score: 0.006
  70. Somatic mitochondrial mutation discovery using ultra-deep sequencing of the mitochondrial genome reveals spatial tumor heterogeneity in head and neck squamous cell carcinoma. Cancer Lett. 2020 02 28; 471:49-60.
    View in: PubMed
    Score: 0.006
  71. Lucitanib for the Treatment of HR+/HER2- Metastatic Breast Cancer: Results from the Multicohort Phase II FINESSE Study. Clin Cancer Res. 2020 01 15; 26(2):354-363.
    View in: PubMed
    Score: 0.006
  72. Mucoepidermoid Carcinoma: A Comparison of Histologic Grading Systems and Relationship to MAML2 Rearrangement and Prognosis. Am J Surg Pathol. 2019 07; 43(7):885-897.
    View in: PubMed
    Score: 0.005
  73. Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer. Nat Med. 2019 07; 25(7):1054-1056.
    View in: PubMed
    Score: 0.005
  74. ATR Inhibition Potentiates the Radiation-induced Inflammatory Tumor Microenvironment. Clin Cancer Res. 2019 06 01; 25(11):3392-3403.
    View in: PubMed
    Score: 0.005
  75. The Endothelin-A Receptor Antagonist Zibotentan Induces Damage to the Nasal Olfactory Epithelium Possibly Mediated in Part through Type 2 Innate Lymphoid Cells. Toxicol Pathol. 2019 02; 47(2):150-164.
    View in: PubMed
    Score: 0.005
  76. Molecular characterisation of aromatase inhibitor-resistant advanced breast cancer: the phenotypic effect of ESR1 mutations. Br J Cancer. 2019 01; 120(2):247-255.
    View in: PubMed
    Score: 0.005
  77. Ablation of Cancer Stem Cells by Therapeutic Inhibition of the MDM2-p53 Interaction in Mucoepidermoid Carcinoma. Clin Cancer Res. 2019 03 01; 25(5):1588-1600.
    View in: PubMed
    Score: 0.005
  78. Ovarian Carcinoma-Associated Mesenchymal Stem Cells Arise from Tissue-Specific Normal Stroma. Stem Cells. 2019 02; 37(2):257-269.
    View in: PubMed
    Score: 0.005
  79. UM-HACC-2A: MYB-NFIB fusion-positive human adenoid cystic carcinoma cell line. Oral Oncol. 2018 12; 87:21-28.
    View in: PubMed
    Score: 0.005
  80. A mathematical model for IL-6-mediated, stem cell driven tumor growth and targeted treatment. PLoS Comput Biol. 2018 01; 14(1):e1005920.
    View in: PubMed
    Score: 0.005
  81. Capecitabine after Surgical Salvage in Recurrent Squamous Cell Carcinoma of Head and Neck. Otolaryngol Head Neck Surg. 2017 12; 157(6):995-997.
    View in: PubMed
    Score: 0.005
  82. Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer. Clin Cancer Res. 2017 Sep 15; 23(18):5561-5572.
    View in: PubMed
    Score: 0.005
  83. EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells. Cancer Res. 2016 11 01; 76(21):6396-6409.
    View in: PubMed
    Score: 0.005
  84. 5T4-Targeted Therapy Ablates Cancer Stem Cells and Prevents Recurrence of Head and Neck Squamous Cell Carcinoma. Clin Cancer Res. 2017 May 15; 23(10):2516-2527.
    View in: PubMed
    Score: 0.005
  85. Therapeutic Inhibition of the MDM2-p53 Interaction Prevents Recurrence of Adenoid Cystic Carcinomas. Clin Cancer Res. 2017 Feb 15; 23(4):1036-1048.
    View in: PubMed
    Score: 0.004
  86. A phase II trial of the BCL-2 homolog domain 3 mimetic AT-101 in combination with docetaxel for recurrent, locally advanced, or metastatic head and neck cancer. Invest New Drugs. 2016 08; 34(4):481-9.
    View in: PubMed
    Score: 0.004
  87. Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor-Positive Breast Cancer. Cancer Res. 2016 04 15; 76(8):2301-13.
    View in: PubMed
    Score: 0.004
  88. Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma. Clin Cancer Res. 2016 07 15; 22(14):3550-9.
    View in: PubMed
    Score: 0.004
  89. Isolation and Characterization of Cancer Stem Cells from Primary Head and Neck Squamous Cell Carcinoma Tumors. Methods Mol Biol. 2016; 1395:241-9.
    View in: PubMed
    Score: 0.004
  90. ALDH/CD44 identifies uniquely tumorigenic cancer stem cells in salivary gland mucoepidermoid carcinomas. Oncotarget. 2015 Sep 29; 6(29):26633-50.
    View in: PubMed
    Score: 0.004
  91. Anti-tumor effect of inhibition of IL-6 signaling in mucoepidermoid carcinoma. Oncotarget. 2015 Sep 08; 6(26):22822-35.
    View in: PubMed
    Score: 0.004
  92. BH3-mimetic small molecule inhibits the growth and recurrence of adenoid cystic carcinoma. Oral Oncol. 2015 Sep; 51(9):839-47.
    View in: PubMed
    Score: 0.004
  93. FGFR signaling promotes the growth of triple-negative and basal-like breast cancer cell lines both in vitro and in vivo. Clin Cancer Res. 2011 Aug 15; 17(16):5275-86.
    View in: PubMed
    Score: 0.003
  94. Postnatal exposure to methyl mercury from fish consumption: a review and new data from the Seychelles Child Development Study. Neurotoxicology. 2009 May; 30(3):338-49.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.