23104097Ring AM, Lin JX, Feng D, Mitra S, Rickert M, Bowman GR, Pande VS, Li P, Moraga I, Spolski R, Ozkan E, Leonard WJ, Garcia KCNature immunologyInterleukin-15; Interleukin-2Animals; Binding Sites; Cell Line, Tumor; Crystallography, X-Ray; Humans; Interleukin-2 Receptor alpha Subunit; Interleukin-2 Receptor beta Subunit; Ligands; Lymphocytes; Mice; Models, Molecular; Molecular Dynamics Simulation; Protein Binding; Protein Multimerization; Protein Structure, Quaternary; Signal TransductionMechanistic and structural insight into the functional dichotomy between IL-2 and IL-15. Nat Immunol. 2012 Dec; 13(12):1187-95.Nat Immunol2012-10-28T00:00:002012Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15.prns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000818Living Beings1457265180.249624AnimalsD001665Chemicals & Drugs32910980.797809Binding SitesAuthorship 107614110.1133290.1133291authors10.2518has subject areaD007376Chemicals & Drugs932490.925346Interleukin-2Biochemistry and Molecular BiologyD008958Concepts & Ideas24512840.706947Models, MolecularD008024Chemicals & Drugs2034330.884647LigandsD011485PhenomenaPhysiology42014540.739266Protein BindingD006801Living Beings2262862810.130052HumansEnginOzkanEngin Ozkan0.000000000000000.000000000000002877Ozkan, EnginAssociate ProfessorD020836Concepts & Ideas65990.969543Protein Structure, QuaternaryD018360Procedures1224840.870736Crystallography, X-RayD019409Chemicals & Drugs24720.937515Interleukin-15D051379Living Beings980113130.368397MiceD053646Chemicals & Drugs220.99965Interleukin-2 Receptor beta SubunitD053645Chemicals & Drugs27360.9857Interleukin-2 Receptor alpha SubunitD055503Phenomena961720.889681Protein MultimerizationD045744Anatomy46824210.643233Cell Line, Tumorhttps://voices.uchicago.edu/ozkanlabThe Özkan Lab at the University of ChicagoD008214Anatomy1994610.840068LymphocytesD015398Physiology69932330.460036Signal TransductionD056004Activities & Behaviors682440.832982Molecular Dynamics SimulationUniversity of Chicagotrue1Associate ProfessorAssociate Professor