D002401Chemicals & DrugsD08.811.277.656.224.125D08.811.277.656.262.500.133D08.811.277.656.300.200.1338120.994112Cathepsin Bprns:emailEncryptedemail addressFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson0.6294680.01392998research area of0.6371750.022764315subject area forMedicine-Infectious Diseases28771332Acar H, Samaeekia R, Schnorenberg MR, Sasmal DK, Huang J, Tirrell MV, LaBelle JLBioconjugate chemistryCathepsin-Mediated Cleavage of Peptides from Peptide Amphiphiles Leads to Enhanced Intracellular Peptide Accumulation. Bioconjug Chem. 2017 09 20; 28(9):2316-2326.Bioconjug Chem2017-08-24T00:00:002017Cathepsin-Mediated Cleavage of Peptides from Peptide Amphiphiles Leads to Enhanced Intracellular Peptide Accumulation.EricPamerEric Pamer41.7886000000000087.598699999999993819Pamer, EricProfessor28951461Bakst RL, Xiong H, Chen CH, Deborde S, Lyubchik A, Zhou Y, He S, McNamara W, Lee SY, Olson OC, Leiner IM, Marcadis AR, Keith JW, Al-Ahmadie HA, Katabi N, Gil Z, Vakiani E, Joyce JA, Pamer E, Wong RJCancer researchInflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression. Cancer Res. 2017 11 15; 77(22):6400-6414.Cancer Res2017-09-26T00:00:002017Inflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression.9582368Mehtani S, Gong Q, Panella J, Subbiah S, Peffley DM, Frankfater AThe Journal of biological chemistryIn vivo expression of an alternatively spliced human tumor message that encodes a truncated form of cathepsin B. Subcellular distribution of the truncated enzyme in COS cells. J Biol Chem. 1998 May 22; 273(21):13236-44.J Biol Chem1998-05-22T00:00:001998In vivo expression of an alternatively spliced human tumor message that encodes a truncated form of cathepsin B. Subcellular distribution of the truncated enzyme in COS cells.Obstetrics and Gynecology-UrogynecologyPediatrics-Hematology and Oncology15090545Bourguignon LY, Singleton PA, Diedrich F, Stern R, Gilad EThe Journal of biological chemistryCD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion. J Biol Chem. 2004 Jun 25; 279(26):26991-7007.J Biol Chem2004-04-16T00:00:002004CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion.https://pamerlab.uchicago.eduPamer Lab websitehttp://dfi.uchicago.eduDuchossois Family Institutehttp://labellelab.uchicago.eduLaBelle LabMargaretMuellerMargaret Mueller41.7886000000000087.598699999999994299Mueller, MargaretAssociate ProfessorNeurologyUniversity of ChicagoRaymond P.RoosxXBmBLI1F+nMg3Vob0H3vWfp+4Wo6r1Xc3h9eaOOFmI=Raymond P. Roos41.78927490000000-87.601250000000001191Roos, Raymond P.ProfessorShu JinChanShu Jin Chan41.78927490000000-87.60125000000000172Chan, Shu Jin19700239Kenig S, Alonso MB, Mueller MM, Lah TTCancer lettersGlioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9. Cancer Lett. 2010 Mar 01; 289(1):53-61.Cancer Lett2009-08-22T00:00:002009Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9.true1true1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professor1010James L.LaBelle3W5oCaQZFemIsW9naE/t8mL1sc65/A==James L. LaBelle0.000000000000000.000000000000002680LaBelle, James L.Associate Professor