D003182Chemicals & DrugsD12.776.124.486.274.45011140.989587Complement C5plugins:TwitterTwitterprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonYangLiYang Li41.7886000000000087.598699999999993543Li, YangAssociate ProfessorLi HuaBaoLi Hua Bao41.7886000000000087.598699999999993707Bao, Li HuaClinical Associate0.7661730.025426711research area of0.5743490.021983110subject area for27018802Jore MM, Johnson S, Sheppard D, Barber NM, Li YI, Nunn MA, Elmlund H, Lea SMNature structural & molecular biologyStructural basis for therapeutic inhibition of complement C5. Nat Struct Mol Biol. 2016 05; 23(5):378-86.Nat Struct Mol Biol2016-03-28T00:00:002016Structural basis for therapeutic inhibition of complement C5.Medicine-Genetic MedicineMedicine-Hospital MedicineObstetrics & Gynecology31545648Frid MG, McKeon BA, Thurman JM, Maron BA, Li M, Zhang H, Kumar S, Sullivan T, Laskowsky J, Fini MA, Hu S, Tuder RM, Gandjeva A, Wilkins MR, Rhodes CJ, Ghataorhe P, Leopold JA, Wang RS, Holers VM, Stenmark KRAmerican journal of respiratory and critical care medicineImmunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension. Am J Respir Crit Care Med. 2020 01 15; 201(2):224-239.Am J Respir Crit Care Med2020-01-15T00:00:002020Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.17533009Puri TS, Quigg RJSeminars in nephrologyThe many effects of complement C3- and C5-binding proteins in renal injury. Semin Nephrol. 2007 May; 27(3):321-37.Semin Nephrol2007-05-01T00:00:002007The many effects of complement C3- and C5-binding proteins in renal injury.21677637Bao L, Wang Y, Haas M, Quigg RJKidney internationalDistinct roles for C3a and C5a in complement-induced tubulointerstitial injury. Kidney Int. 2011 Sep; 80(5):524-34.Kidney Int2011-06-15T00:00:002011Distinct roles for C3a and C5a in complement-induced tubulointerstitial injury.22688254Qu XW, Jilling T, Neerhof MG, Luo K, Hirsch E, Thaete LGJournal of reproductive immunologyUnilateral uterine ischemia/reperfusion-induced bilateral fetal loss and fetal growth restriction in a murine model require intact complement component 5. J Reprod Immunol. 2012 Sep; 95(1-2):27-35.J Reprod Immunol2012-06-09T00:00:002012Unilateral uterine ischemia/reperfusion-induced bilateral fetal loss and fetal growth restriction in a murine model require intact complement component 5.https://thelilab.com/Li Labyang_i_liMedicineUniversity of ChicagoTipu S.PuriTipu S. Puri41.78927490000000-87.601250000000001602Puri, Tipu S.Associate ProfessorEmmetHirschEmmet Hirsch41.78927490000000-87.60125000000000509Hirsch, EmmetClinical ProfessorRichardQuiggRichard Quigg41.78927490000000-87.60125000000000527Quigg, RichardEmeritus/Emerita, Professortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1Associate ProfessorAssociate Professortrue1Clinical AssociateClinical Associatetrue1Associate ProfessorAssociate Professortrue1Clinical ProfessorClinical ProfessorMedicine-Nephrology