23060426Stein EA, Dufour R, Gagne C, Gaudet D, East C, Donovan JM, Chin W, Tribble DL, McGowan MCirculationApolipoproteins B; Coronary Artery Disease; Heterozygote; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; OligonucleotidesAlanine Transaminase; Anticholesteremic Agents; Bilirubin; Comorbidity; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Subcutaneous; Liver; Magnetic Resonance Imaging; Male; Middle Aged; Oligonucleotides, Antisense; Treatment OutcomeApolipoprotein B synthesis inhibition with mipomersen in heterozygous familial hypercholesterolemia: results of a randomized, double-blind, placebo-controlled trial to assess efficacy and safety as add-on therapy in patients with coronary artery disease. Circulation. 2012 Nov 06; 126(19):2283-92.Circulation2012-10-11T00:00:002012Apolipoprotein B synthesis inhibition with mipomersen in heterozygous familial hypercholesterolemia: results of a randomized, double-blind, placebo-controlled trial to assess efficacy and safety as add-on therapy in patients with coronary artery disease.prns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAuthorshipvivo:hasSubjectAreahas subject areaInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedInformationResourcelinked information resourcerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptD000410Chemicals & Drugs44730.977989Alanine TransaminaseD001055Chemicals & Drugs13380.987813Apolipoproteins BD001663Chemicals & Drugs541240.967103BilirubinD003324Disorders1163470.700518Coronary Artery DiseaseD004311Procedures33818220.708936Double-Blind MethodD004359Procedures2748930.819188Drug Therapy, CombinationAuthorship 1180660.2259280.2259281authors10.2521has subject areaD006938Disorders9180.979205Hyperlipoproteinemia Type IID008875Concepts & IdeasLiving Beings1473249570.258811Middle AgedD008099Anatomy34612290.672325LiverD005260Physiology1992444050.191167FemaleD006801Living Beings2262862810.130052HumansD008297Physiology1931408600.201617MaleD015897Concepts & Ideas3839430.744448ComorbidityD016896Concepts & Ideas101179490.402389Treatment OutcomeD019161Chemicals & Drugs893780.727233Hydroxymethylglutaryl-CoA Reductase InhibitorsD000924Chemicals & Drugs221370.887985Anticholesteremic AgentsD006579Living Beings1553650.903231HeterozygoteD007279Procedures741170.97305Injections, SubcutaneousD008279Concepts & IdeasProcedures53033470.417684Magnetic Resonance ImagingD009841Chemicals & Drugs58920.940206OligonucleotidesD016376Chemicals & Drugs47690.974047Oligonucleotides, Antisense